Click here to switch to the map view.

The map label for this gene is nfuA

Identifier: 119946808

GI number: 119946808

Start: 3955845

End: 3956426

Strand: Direct

Name: nfuA

Synonym: Ping_3202

Alternate gene names: 119946808

Gene position: 3955845-3956426 (Clockwise)

Preceding gene: 119946807

Following gene: 119946809

Centisome position: 86.76

GC content: 39.18

Gene sequence:

>582_bases
ATGATTGAAATCACTCCAATTGCACAAGCACATTTTAAAAAATTACTTGAACCACAAAAAGAAGGAACACACATTCGCGT
GTTTGTTATTAATCCCGGCACAGCTAAAGCTGAATGCGGTGTTTCATATTGCCCACCTGAAGCTGTCGAAAGCAGTGATA
CACGGTTAACTTTTGATGGGTTTGATGCATTGATTGATGAGGTTAGTGTACCCTTTTTAGAAGATGCCTTTGTAGATTTA
GTGGAAGAGGATGCGGGAACTCAGCTGACCCTTAAGGCACCCAATGCAAAAATGCGTAAAGTAAAAGACGATGCGCCACT
ACTTGAACGTGTTGAATATGTTATCCAGGTTCAAATAAATCCACAACTGGCAAGCCACGGTGGTTTTATCAAATTAATAG
AAATAACAGAGGATAATGTTGCTATTATTGAATTTGGTGGTGGTTGTAACGGTTGCTCTCAAGTTGATTTGACACTCAAA
CAAGGTGTTGAAAAAGAGCTGATAGACGAATTTTCTGGCGAGCTAAATGCTGTGAGAGATATCACCGAACATGAAAGTGG
CGATCACTCTTTTTATAAATAA

Upstream 100 bases:

>100_bases
CCATAAGTGCTTTTCCTGCAGGAAGTAAAATAATCACTATTATTTTACTTCTTATTATTTATAATGGTTGAGTAAATTAC
TCAAGAATAAAGGCCCGACT

Downstream 100 bases:

>100_bases
AAAGATTCTTTAACAAGGGCTAAAGCAAACTTAGCCCTTATTTAAAAGTACGAAATACTCCTCATAATGTATTCACTTCC
TCCAATTAATCCAGCCAATA

Product: putative DNA uptake protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MIEITPIAQAHFKKLLEPQKEGTHIRVFVINPGTAKAECGVSYCPPEAVESSDTRLTFDGFDALIDEVSVPFLEDAFVDL
VEEDAGTQLTLKAPNAKMRKVKDDAPLLERVEYVIQVQINPQLASHGGFIKLIEITEDNVAIIEFGGGCNGCSQVDLTLK
QGVEKELIDEFSGELNAVRDITEHESGDHSFYK

Sequences:

>Translated_193_residues
MIEITPIAQAHFKKLLEPQKEGTHIRVFVINPGTAKAECGVSYCPPEAVESSDTRLTFDGFDALIDEVSVPFLEDAFVDL
VEEDAGTQLTLKAPNAKMRKVKDDAPLLERVEYVIQVQINPQLASHGGFIKLIEITEDNVAIIEFGGGCNGCSQVDLTLK
QGVEKELIDEFSGELNAVRDITEHESGDHSFYK
>Mature_193_residues
MIEITPIAQAHFKKLLEPQKEGTHIRVFVINPGTAKAECGVSYCPPEAVESSDTRLTFDGFDALIDEVSVPFLEDAFVDL
VEEDAGTQLTLKAPNAKMRKVKDDAPLLERVEYVIQVQINPQLASHGGFIKLIEITEDNVAIIEFGGGCNGCSQVDLTLK
QGVEKELIDEFSGELNAVRDITEHESGDHSFYK

Specific function: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins

COG id: COG0694

COG function: function code O; Thioredoxin-like proteins and domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nfuA family

Homologues:

Organism=Escherichia coli, GI1789819, Length=192, Percent_Identity=67.7083333333333, Blast_Score=280, Evalue=4e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NFUA_PSYIN (A1SZH4)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_944488.1
- ProteinModelPortal:   A1SZH4
- STRING:   A1SZH4
- GeneID:   4624811
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_3202
- eggNOG:   COG0694
- HOGENOM:   HBG289644
- OMA:   CQGCSAV
- PhylomeDB:   A1SZH4
- ProtClustDB:   PRK11190
- BioCyc:   PING357804:PING_3202-MONOMER
- HAMAP:   MF_01637
- InterPro:   IPR017726
- InterPro:   IPR000361
- InterPro:   IPR001075
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- ProDom:   PD002830
- TIGRFAMs:   TIGR03341

Pfam domain/function: PF01521 Fe-S_biosyn; PF01106 NifU; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 21248; Mature: 21248

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEITPIAQAHFKKLLEPQKEGTHIRVFVINPGTAKAECGVSYCPPEAVESSDTRLTFDG
CEEECCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHCCCCCCEEEECH
FDALIDEVSVPFLEDAFVDLVEEDAGTQLTLKAPNAKMRKVKDDAPLLERVEYVIQVQIN
HHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHCCCCCHHHHHEEEEEEEEEC
PQLASHGGFIKLIEITEDNVAIIEFGGGCNGCSQVDLTLKQGVEKELIDEFSGELNAVRD
CCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCEEEEHHHCCCHHHHHHHHCCHHHHHHH
ITEHESGDHSFYK
HHHCCCCCCCCCC
>Mature Secondary Structure
MIEITPIAQAHFKKLLEPQKEGTHIRVFVINPGTAKAECGVSYCPPEAVESSDTRLTFDG
CEEECCCHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCHHHCCCCCCEEEECH
FDALIDEVSVPFLEDAFVDLVEEDAGTQLTLKAPNAKMRKVKDDAPLLERVEYVIQVQIN
HHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHCCCCCHHHHHEEEEEEEEEC
PQLASHGGFIKLIEITEDNVAIIEFGGGCNGCSQVDLTLKQGVEKELIDEFSGELNAVRD
CCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCEEEEHHHCCCHHHHHHHHCCHHHHHHH
ITEHESGDHSFYK
HHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA