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The map label for this gene is slyD [H]

Identifier: 119946805

GI number: 119946805

Start: 3953232

End: 3953750

Strand: Direct

Name: slyD [H]

Synonym: Ping_3199

Alternate gene names: 119946805

Gene position: 3953232-3953750 (Clockwise)

Preceding gene: 119946804

Following gene: 119946807

Centisome position: 86.7

GC content: 42.39

Gene sequence:

>519_bases
ATGAGAAATAATATGAAAATTACAAATGACTCAGTGGTTTCAATCCACTTCGGCGTTTCAGAAGTAGACGGTAACGCATT
AGACAGCACTGAAAATGGTGCTCCACTTGAATTCATTCAAGGTTCACATTATTTGGTCCCAGGCTTAGAAGCTGAATTAG
AAGGCAAACAGCTTGGTGATAAATTTGACGTTGAATTAGAAGCTAAAGATGCATATGGCCTTTTCCAGGACGAATTAGTA
CAACAAGTACCACGTTCTTTATTCGAAGGTGTTGATGAAATTGAAGTAGGCATGTCATTCCAAGCTGAAACAGATCAAGG
ACCACGCTCCGTTGAAGTCACCGAAGTCGGTGAAGAAAATGTCAGTATTGATGCAAATCATCCGCTAGCTGGTATGGCTT
TAAAATTTGTAGGTGAAGTTATTGGCGTTCGCGCCGCAACCGAAGAAGAATTAGCGCATGGTCATACTCACCCGGCGGCC
AGCGAAGAAAAAGAAGCCGTTGAAGCAGCTAACGCATAA

Upstream 100 bases:

>100_bases
ACACAAACACAAACACCGCAACAAGCAACATCGGCAACACGCCAATTTGAACAAATTATCGGTGTGTTTGATCCGAATGA
AATTGAATAAAACTTAAATA

Downstream 100 bases:

>100_bases
CGCGCAAGGTGATAGTTATTGCGCAGACCCTCATGAAACAAGTTATGAATGCTGCAATGGAGATCACTAAGATCTGATTG
ATTGAATGACAGTTTAATTT

Product: peptidylprolyl isomerase, FKBP-type

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MRNNMKITNDSVVSIHFGVSEVDGNALDSTENGAPLEFIQGSHYLVPGLEAELEGKQLGDKFDVELEAKDAYGLFQDELV
QQVPRSLFEGVDEIEVGMSFQAETDQGPRSVEVTEVGEENVSIDANHPLAGMALKFVGEVIGVRAATEEELAHGHTHPAA
SEEKEAVEAANA

Sequences:

>Translated_172_residues
MRNNMKITNDSVVSIHFGVSEVDGNALDSTENGAPLEFIQGSHYLVPGLEAELEGKQLGDKFDVELEAKDAYGLFQDELV
QQVPRSLFEGVDEIEVGMSFQAETDQGPRSVEVTEVGEENVSIDANHPLAGMALKFVGEVIGVRAATEEELAHGHTHPAA
SEEKEAVEAANA
>Mature_172_residues
MRNNMKITNDSVVSIHFGVSEVDGNALDSTENGAPLEFIQGSHYLVPGLEAELEGKQLGDKFDVELEAKDAYGLFQDELV
QQVPRSLFEGVDEIEVGMSFQAETDQGPRSVEVTEVGEENVSIDANHPLAGMALKFVGEVIGVRAATEEELAHGHTHPAA
SEEKEAVEAANA

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=148, Percent_Identity=52.027027027027, Blast_Score=150, Evalue=3e-38,
Organism=Escherichia coli, GI1786211, Length=146, Percent_Identity=34.2465753424658, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 18491; Mature: 18491

Theoretical pI: Translated: 3.98; Mature: 3.98

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNNMKITNDSVVSIHFGVSEVDGNALDSTENGAPLEFIQGSHYLVPGLEAELEGKQLGD
CCCCCEECCCCEEEEEECCEECCCCCCCCCCCCCCEEEECCCEEECCCCCCCCCCCCCCC
KFDVELEAKDAYGLFQDELVQQVPRSLFEGVDEIEVGMSFQAETDQGPRSVEVTEVGEEN
EECEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCEEECCCCCCCCEEEEEECCCCC
VSIDANHPLAGMALKFVGEVIGVRAATEEELAHGHTHPAASEEKEAVEAANA
EEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure
MRNNMKITNDSVVSIHFGVSEVDGNALDSTENGAPLEFIQGSHYLVPGLEAELEGKQLGD
CCCCCEECCCCEEEEEECCEECCCCCCCCCCCCCCEEEECCCEEECCCCCCCCCCCCCCC
KFDVELEAKDAYGLFQDELVQQVPRSLFEGVDEIEVGMSFQAETDQGPRSVEVTEVGEEN
EECEEEECCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCEEECCCCCCCCEEEEEECCCCC
VSIDANHPLAGMALKFVGEVIGVRAATEEELAHGHTHPAASEEKEAVEAANA
EEEECCCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]