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The map label for this gene is glpR [H]

Identifier: 119946783

GI number: 119946783

Start: 3910787

End: 3911599

Strand: Direct

Name: glpR [H]

Synonym: Ping_3176

Alternate gene names: 119946783

Gene position: 3910787-3911599 (Clockwise)

Preceding gene: 119946782

Following gene: 119946786

Centisome position: 85.77

GC content: 41.57

Gene sequence:

>813_bases
ATGAGGGAATTAAGTTCACAGTACCAGGAGCAGAGTTTCGTGAAGCAAACTACAAGACATCAGAAAATCATCGATCTCGT
CTATAAAAATGGATATGTCAGTACCGAGGACTTTGTTGAGCACTTTAAAGTAAGTCCTCAGACTATTCGCCGAGATTTAA
ATGAACTGGCCGATGCAAATAAAATACGCCGCCATCATGGTGGCGCAACGACCCCGCTGAGCTCTATCAATACCGCTTAT
AATACCCGTAAAGCCATGCAGCTAACCGAAAAAGACAGCATTGCAGAAGCCTTAGTAAAATATATTCCTAACGGTGCGAC
ACTGTTTATCGATATTGGTACGACGCCGGAATCCATTGCGCGAGAATTAGCAAAAACGCACAAAAATTTACAGATTGTGA
CCAATAATATCAATGCAGCCTTTATATTGATGGGCAATGAGGATTTTAAAGTTATCCTGGCCGGCGGTGAAGTGCGTAAT
AAAGACGGCGGTATCGTCGGTGAGGCGACGCTGGATTTCATTAAACAGTTCCGTTTAGATTTTGGTATTTTGGGTATCAG
CGGGATTGATTATGATGGTTCGTTATTAGATTTTGATTATCATGAAGTGCGGGTTAAAAAAGCCATTATAGAAAATAGCC
GCAGTGTCTATCTCGCGGTTGACCATACAAAATTCGGGCGTAATGCGATGGTTAAATTGGGTAATATAGCGGAAATAGAT
ATGCTGATAACAAATAGGCCGCCACCCAAAGAAATCACTACATTATTAAAAGCGCACAAGATTCCATTTGAAGTGGTTCC
AAAGGAGCGCTAA

Upstream 100 bases:

>100_bases
TTCGAAACTAATAACCATTCTATCACTCAGCAACCTTGTTATTTCATTGCTATTCATCACCGTCACGGTAAAATTATTTC
ATTAAACTTATTTCATTAAA

Downstream 100 bases:

>100_bases
AGTAGTAAGCACTTATCATTTTGATAAGTGCTTACTATTAATTAACGGTAAGACTCACTTTTTTTGTGCTTGTAAAAAGT
TAACCGCACGATCCGGGTAA

Product: transcriptional regulator of DeoR family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MRELSSQYQEQSFVKQTTRHQKIIDLVYKNGYVSTEDFVEHFKVSPQTIRRDLNELADANKIRRHHGGATTPLSSINTAY
NTRKAMQLTEKDSIAEALVKYIPNGATLFIDIGTTPESIARELAKTHKNLQIVTNNINAAFILMGNEDFKVILAGGEVRN
KDGGIVGEATLDFIKQFRLDFGILGISGIDYDGSLLDFDYHEVRVKKAIIENSRSVYLAVDHTKFGRNAMVKLGNIAEID
MLITNRPPPKEITTLLKAHKIPFEVVPKER

Sequences:

>Translated_270_residues
MRELSSQYQEQSFVKQTTRHQKIIDLVYKNGYVSTEDFVEHFKVSPQTIRRDLNELADANKIRRHHGGATTPLSSINTAY
NTRKAMQLTEKDSIAEALVKYIPNGATLFIDIGTTPESIARELAKTHKNLQIVTNNINAAFILMGNEDFKVILAGGEVRN
KDGGIVGEATLDFIKQFRLDFGILGISGIDYDGSLLDFDYHEVRVKKAIIENSRSVYLAVDHTKFGRNAMVKLGNIAEID
MLITNRPPPKEITTLLKAHKIPFEVVPKER
>Mature_270_residues
MRELSSQYQEQSFVKQTTRHQKIIDLVYKNGYVSTEDFVEHFKVSPQTIRRDLNELADANKIRRHHGGATTPLSSINTAY
NTRKAMQLTEKDSIAEALVKYIPNGATLFIDIGTTPESIARELAKTHKNLQIVTNNINAAFILMGNEDFKVILAGGEVRN
KDGGIVGEATLDFIKQFRLDFGILGISGIDYDGSLLDFDYHEVRVKKAIIENSRSVYLAVDHTKFGRNAMVKLGNIAEID
MLITNRPPPKEITTLLKAHKIPFEVVPKER

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=253, Percent_Identity=64.8221343873518, Blast_Score=343, Evalue=7e-96,
Organism=Escherichia coli, GI87082344, Length=251, Percent_Identity=38.2470119521912, Blast_Score=201, Evalue=4e-53,
Organism=Escherichia coli, GI1788069, Length=247, Percent_Identity=29.5546558704453, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789170, Length=233, Percent_Identity=28.755364806867, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789519, Length=262, Percent_Identity=27.4809160305344, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI226510968, Length=252, Percent_Identity=27.7777777777778, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787540, Length=228, Percent_Identity=30.2631578947368, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789059, Length=235, Percent_Identity=27.6595744680851, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790635, Length=252, Percent_Identity=27.7777777777778, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1790753, Length=238, Percent_Identity=23.109243697479, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 30386; Mature: 30386

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2 ; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRELSSQYQEQSFVKQTTRHQKIIDLVYKNGYVSTEDFVEHFKVSPQTIRRDLNELADAN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
KIRRHHGGATTPLSSINTAYNTRKAMQLTEKDSIAEALVKYIPNGATLFIDIGTTPESIA
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHH
RELAKTHKNLQIVTNNINAAFILMGNEDFKVILAGGEVRNKDGGIVGEATLDFIKQFRLD
HHHHHHCCCEEEEEECCCEEEEEECCCCEEEEEECCCEECCCCCEEHHHHHHHHHHHHHH
FGILGISGIDYDGSLLDFDYHEVRVKKAIIENSRSVYLAVDHTKFGRNAMVKLGNIAEID
HEEEEECCCCCCCCEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEECCEEEEE
MLITNRPPPKEITTLLKAHKIPFEVVPKER
EEECCCCCHHHHHHHHHHHCCCEEECCCCC
>Mature Secondary Structure
MRELSSQYQEQSFVKQTTRHQKIIDLVYKNGYVSTEDFVEHFKVSPQTIRRDLNELADAN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHH
KIRRHHGGATTPLSSINTAYNTRKAMQLTEKDSIAEALVKYIPNGATLFIDIGTTPESIA
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHH
RELAKTHKNLQIVTNNINAAFILMGNEDFKVILAGGEVRNKDGGIVGEATLDFIKQFRLD
HHHHHHCCCEEEEEECCCEEEEEECCCCEEEEEECCCEECCCCCEEHHHHHHHHHHHHHH
FGILGISGIDYDGSLLDFDYHEVRVKKAIIENSRSVYLAVDHTKFGRNAMVKLGNIAEID
HEEEEECCCCCCCCEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEECCEEEEE
MLITNRPPPKEITTLLKAHKIPFEVVPKER
EEECCCCCHHHHHHHHHHHCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]