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The map label for this gene is gcd [H]

Identifier: 119946704

GI number: 119946704

Start: 3788809

End: 3791136

Strand: Direct

Name: gcd [H]

Synonym: Ping_3086

Alternate gene names: 119946704

Gene position: 3788809-3791136 (Clockwise)

Preceding gene: 119946702

Following gene: 119946707

Centisome position: 83.1

GC content: 47.16

Gene sequence:

>2328_bases
ATGCGTTTTTTTTCCATATTAGGATGGATTGTAGGTCTTACCCTTACCCTTGGTGGAGGATATTTACTCTCTCTTGGTGG
CAGTGCTTACTACTTGATAGCGGGAATTGTGCTACTGATTACCAGTGGTTTAGCATTTAAACGCCAACCATCGTCTTTGT
ATCTTTATAGTATTTTTCTGCTTGGCACTTTTATCTGGGCGCTTAGCGAATCGGGTTATTATTGGTGGGGGTTAGCACCA
CGCCTTGGTCTCTTTTTAGCCATCGCTCTGCCACTCTTTTTTACACGCTCATGGTCCGTAAGCCGGAAAATACTTGTGGC
GGTATGGACAATTATTACGCTTGTGATGCTGGCAAGTTTAATAAATGCACCTTTCGATAAGCAAGGTGAATTACCTATGG
CAAGTATTAATGCAAATACCGAGGACAGTGTGCCTAAAGGGGACTGGAATGCGTATGGTCGTTCTAATCTCGGGCAGCGA
TATTCTCCACTTGAGGATATCACGCCAGATAATATCGCTAATCTCAAACAAGCTTGGGTATACCGAACCGGTGATATGAA
GGGGCCTAAAGACGTCGGTGAAACCACCTATGAGGCGACACCATTAAAAGTGGGTAATAGTTTATATCTTTGTACACCAC
ATAATTGGTTGGTGGCGTTAGATGCGGATAGTGGTGAGAAACGTTGGGTTTATGACTCTAAAGTCTTGCCTGAGATGCAA
CGTCAGCACCAAACCTGTCGGGGAGTTTCTTATCAACCCCCTGCATCAGGGACTATCCCAATGGCGATAAATCAAACTCA
GCCATCCGAAAATCTAGCTTCGGTTAGCTGTGACGCGAAGTTATTTTTACCAACATCAGATGCACGCCTGATTGCGTTGG
ATCCTGTTACTGGCGCTCGTTGCCAAGGATTTGGTGACGATGGCGTTATTGATTTAACCAAAAACATGCCCTTTAAGCAG
GCCGGTTACTATTACTCTACATCACCGCCTTTAGTTTCCAATGGTTTTGTGGTTGTCGGCGGTTCGGTTAACGATAACTA
TGATGTGAATGAGCCTTCGGGTGTTATTCGTGCCTACAATACCAGTACGGGTGAATTGGCATGGAACTGGGATTCGGGAA
ATCCAGATGAGACTGCCCCGATAGGCCCAAATGAAACCTACGCAGTTAGCTCACCCAATAGTTGGTCGATCGCGAGTGCA
GATGACAAACTCGGTCTTATCTATTTACCGATGGGCAACAGTACCCCCGATCAGTTAGGTATGTATCGCTCACCGGCCGA
AGAGAAATATGCAACATCGGTTGTTGCGCTGCATATCGAGACGGGTAAAGTTGCTTGGGTGCAACAGTTCATCCACCATG
ATTTGTGGGATATGGACACACCCGCTCAACCGTCGTTACTAGATCTTCAAACTAAAAGCGGCCTTCAGCCTGCATTGGTC
GTTCCGACCAAACAGGGTGACGTGTATGTACTGAATCGTAAGACAGGTGAACCGATTATACCGATCACCGAGCAACCAGC
CCCACAAGGAACCATTCCTGAAGATTATGCTTCGCCTACACAACCAAGCTCTGCGTTAAACTTTAAGCCAGAGAAAATGA
CCGGTGCGCAGATGTGGGGTGCAACACCTATTGATCAACTGATTTGCCGTATTCAGTTTAAAAAATTACGCTATGAAGGC
CAGTACACACCACCATCTATACAAGGTACTCTTGTTTACCCGGGTAACTTTGGCGTGTTCAACTGGGGCGGCGTTGCGGT
TGATCCTGAACGTCAGGTGATGTTTGCTATGCCACTGGATTTGGCCTTTGTATCGAAATTGATCCCCAATGATAATCAGC
AAGATCTTGGTCCGGTCAATACGGGTGAACAGGGTGTGAGCACTAATACTGGTAGCCCGTATTCTGTGTCACTATCGCCT
TTCTTATCGCCACTTGGCATACCCTGTCAGCAGCCACCTTGGGGTTCTGTTGCCGGTGTGAATTTAAGAACAGGTGAAAA
GGTATGGCAGCACAAAAATGGCACGACTCGAGATATGACTGCACTGCCACTGCCTATCCCATTGGGGATGCCGGGCATTG
GCGGGCCGATTATCACCAAAGGCGGTGTTGCATTCATGGCAGCATCACTGGATGACTATTTACGTGGGTACGATCTCAAA
ACCGGGCAAGTGTTATGGACGGCAAGATTACCTGCCGGTGGACAAGCCACACCCATGACCTACCTAAACAGCAAAGGTGA
ACAGATGGTGGTTCAGGTCGCGGGTGGACATGGTTCACTTGGCACTACCTTAGGTGACTATGTGGTGGCTTATAAACTAG
AAAAATAG

Upstream 100 bases:

>100_bases
TTTACTGTGATAACAAAATGTTACAAATAAACCTTAAAGCTTTGATGAATAATTTACGCCATATCCATTCAGCTCAGCTT
CTATTCAAATGGAGTCATCT

Downstream 100 bases:

>100_bases
AGCTGAATAAAATCTACTGGCAAGTCTGGTGGGTGAATATAGGCAGGATAAAAGGCTTTTATTCTTCCTATACTCAATTC
AGATTGATCTTAGCGACACA

Product: glucose dehydrogenase

Products: NA

Alternate protein names: Glucose dehydrogenase [pyrroloquinoline-quinone] [H]

Number of amino acids: Translated: 775; Mature: 775

Protein sequence:

>775_residues
MRFFSILGWIVGLTLTLGGGYLLSLGGSAYYLIAGIVLLITSGLAFKRQPSSLYLYSIFLLGTFIWALSESGYYWWGLAP
RLGLFLAIALPLFFTRSWSVSRKILVAVWTIITLVMLASLINAPFDKQGELPMASINANTEDSVPKGDWNAYGRSNLGQR
YSPLEDITPDNIANLKQAWVYRTGDMKGPKDVGETTYEATPLKVGNSLYLCTPHNWLVALDADSGEKRWVYDSKVLPEMQ
RQHQTCRGVSYQPPASGTIPMAINQTQPSENLASVSCDAKLFLPTSDARLIALDPVTGARCQGFGDDGVIDLTKNMPFKQ
AGYYYSTSPPLVSNGFVVVGGSVNDNYDVNEPSGVIRAYNTSTGELAWNWDSGNPDETAPIGPNETYAVSSPNSWSIASA
DDKLGLIYLPMGNSTPDQLGMYRSPAEEKYATSVVALHIETGKVAWVQQFIHHDLWDMDTPAQPSLLDLQTKSGLQPALV
VPTKQGDVYVLNRKTGEPIIPITEQPAPQGTIPEDYASPTQPSSALNFKPEKMTGAQMWGATPIDQLICRIQFKKLRYEG
QYTPPSIQGTLVYPGNFGVFNWGGVAVDPERQVMFAMPLDLAFVSKLIPNDNQQDLGPVNTGEQGVSTNTGSPYSVSLSP
FLSPLGIPCQQPPWGSVAGVNLRTGEKVWQHKNGTTRDMTALPLPIPLGMPGIGGPIITKGGVAFMAASLDDYLRGYDLK
TGQVLWTARLPAGGQATPMTYLNSKGEQMVVQVAGGHGSLGTTLGDYVVAYKLEK

Sequences:

>Translated_775_residues
MRFFSILGWIVGLTLTLGGGYLLSLGGSAYYLIAGIVLLITSGLAFKRQPSSLYLYSIFLLGTFIWALSESGYYWWGLAP
RLGLFLAIALPLFFTRSWSVSRKILVAVWTIITLVMLASLINAPFDKQGELPMASINANTEDSVPKGDWNAYGRSNLGQR
YSPLEDITPDNIANLKQAWVYRTGDMKGPKDVGETTYEATPLKVGNSLYLCTPHNWLVALDADSGEKRWVYDSKVLPEMQ
RQHQTCRGVSYQPPASGTIPMAINQTQPSENLASVSCDAKLFLPTSDARLIALDPVTGARCQGFGDDGVIDLTKNMPFKQ
AGYYYSTSPPLVSNGFVVVGGSVNDNYDVNEPSGVIRAYNTSTGELAWNWDSGNPDETAPIGPNETYAVSSPNSWSIASA
DDKLGLIYLPMGNSTPDQLGMYRSPAEEKYATSVVALHIETGKVAWVQQFIHHDLWDMDTPAQPSLLDLQTKSGLQPALV
VPTKQGDVYVLNRKTGEPIIPITEQPAPQGTIPEDYASPTQPSSALNFKPEKMTGAQMWGATPIDQLICRIQFKKLRYEG
QYTPPSIQGTLVYPGNFGVFNWGGVAVDPERQVMFAMPLDLAFVSKLIPNDNQQDLGPVNTGEQGVSTNTGSPYSVSLSP
FLSPLGIPCQQPPWGSVAGVNLRTGEKVWQHKNGTTRDMTALPLPIPLGMPGIGGPIITKGGVAFMAASLDDYLRGYDLK
TGQVLWTARLPAGGQATPMTYLNSKGEQMVVQVAGGHGSLGTTLGDYVVAYKLEK
>Mature_775_residues
MRFFSILGWIVGLTLTLGGGYLLSLGGSAYYLIAGIVLLITSGLAFKRQPSSLYLYSIFLLGTFIWALSESGYYWWGLAP
RLGLFLAIALPLFFTRSWSVSRKILVAVWTIITLVMLASLINAPFDKQGELPMASINANTEDSVPKGDWNAYGRSNLGQR
YSPLEDITPDNIANLKQAWVYRTGDMKGPKDVGETTYEATPLKVGNSLYLCTPHNWLVALDADSGEKRWVYDSKVLPEMQ
RQHQTCRGVSYQPPASGTIPMAINQTQPSENLASVSCDAKLFLPTSDARLIALDPVTGARCQGFGDDGVIDLTKNMPFKQ
AGYYYSTSPPLVSNGFVVVGGSVNDNYDVNEPSGVIRAYNTSTGELAWNWDSGNPDETAPIGPNETYAVSSPNSWSIASA
DDKLGLIYLPMGNSTPDQLGMYRSPAEEKYATSVVALHIETGKVAWVQQFIHHDLWDMDTPAQPSLLDLQTKSGLQPALV
VPTKQGDVYVLNRKTGEPIIPITEQPAPQGTIPEDYASPTQPSSALNFKPEKMTGAQMWGATPIDQLICRIQFKKLRYEG
QYTPPSIQGTLVYPGNFGVFNWGGVAVDPERQVMFAMPLDLAFVSKLIPNDNQQDLGPVNTGEQGVSTNTGSPYSVSLSP
FLSPLGIPCQQPPWGSVAGVNLRTGEKVWQHKNGTTRDMTALPLPIPLGMPGIGGPIITKGGVAFMAASLDDYLRGYDLK
TGQVLWTARLPAGGQATPMTYLNSKGEQMVVQVAGGHGSLGTTLGDYVVAYKLEK

Specific function: GDH is probably involved in energy conservation rather than in sugar metabolism [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial PQQ dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=789, Percent_Identity=45.7541191381496, Blast_Score=683, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017511
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.5.2 [H]

Molecular weight: Translated: 84071; Mature: 84071

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFFSILGWIVGLTLTLGGGYLLSLGGSAYYLIAGIVLLITSGLAFKRQPSSLYLYSIFL
CHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHH
LGTFIWALSESGYYWWGLAPRLGLFLAIALPLFFTRSWSVSRKILVAVWTIITLVMLASL
HHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
INAPFDKQGELPMASINANTEDSVPKGDWNAYGRSNLGQRYSPLEDITPDNIANLKQAWV
HCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHE
YRTGDMKGPKDVGETTYEATPLKVGNSLYLCTPHNWLVALDADSGEKRWVYDSKVLPEMQ
EECCCCCCCHHHCCCCCCCCCEEECCEEEEECCCCEEEEEECCCCCCEEEECCHHHHHHH
RQHQTCRGVSYQPPASGTIPMAINQTQPSENLASVSCDAKLFLPTSDARLIALDPVTGAR
HHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCEEEECCEEEEEECCCCEEEEECCCCCCC
CQGFGDDGVIDLTKNMPFKQAGYYYSTSPPLVSNGFVVVGGSVNDNYDVNEPSGVIRAYN
CCCCCCCCEEEECCCCCCHHCCEEEECCCCEEECCEEEECCCCCCCCCCCCCCCEEEEEE
TSTGELAWNWDSGNPDETAPIGPNETYAVSSPNSWSIASADDKLGLIYLPMGNSTPDQLG
CCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCCEEECCCCCEEEEEEECCCCCHHHHC
MYRSPAEEKYATSVVALHIETGKVAWVQQFIHHDLWDMDTPAQPSLLDLQTKSGLQPALV
CCCCCCHHHHCEEEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEEHHHCCCCCEEE
VPTKQGDVYVLNRKTGEPIIPITEQPAPQGTIPEDYASPTQPSSALNFKPEKMTGAQMWG
EECCCCCEEEEECCCCCCEEECCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCHHCC
ATPIDQLICRIQFKKLRYEGQYTPPSIQGTLVYPGNFGVFNWGGVAVDPERQVMFAMPLD
CCCHHHHHHHHHHHHHEECCCCCCCCCEEEEEECCCCCEEECCCEEECCCCCEEEECCHH
LAFVSKLIPNDNQQDLGPVNTGEQGVSTNTGSPYSVSLSPFLSPLGIPCQQPPWGSVAGV
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHCCCCCCCCCCCCCCCCEEEE
NLRTGEKVWQHKNGTTRDMTALPLPIPLGMPGIGGPIITKGGVAFMAASLDDYLRGYDLK
EECCCHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCEEECCCCEEEHHHHHHHHHCCCCC
TGQVLWTARLPAGGQATPMTYLNSKGEQMVVQVAGGHGSLGTTLGDYVVAYKLEK
CCCEEEEEECCCCCCCCCHHEECCCCCEEEEEEECCCCCCCCHHCCEEEEEEECC
>Mature Secondary Structure
MRFFSILGWIVGLTLTLGGGYLLSLGGSAYYLIAGIVLLITSGLAFKRQPSSLYLYSIFL
CHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHH
LGTFIWALSESGYYWWGLAPRLGLFLAIALPLFFTRSWSVSRKILVAVWTIITLVMLASL
HHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
INAPFDKQGELPMASINANTEDSVPKGDWNAYGRSNLGQRYSPLEDITPDNIANLKQAWV
HCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCHHHHHHHHHE
YRTGDMKGPKDVGETTYEATPLKVGNSLYLCTPHNWLVALDADSGEKRWVYDSKVLPEMQ
EECCCCCCCHHHCCCCCCCCCEEECCEEEEECCCCEEEEEECCCCCCEEEECCHHHHHHH
RQHQTCRGVSYQPPASGTIPMAINQTQPSENLASVSCDAKLFLPTSDARLIALDPVTGAR
HHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCEEEECCEEEEEECCCCEEEEECCCCCCC
CQGFGDDGVIDLTKNMPFKQAGYYYSTSPPLVSNGFVVVGGSVNDNYDVNEPSGVIRAYN
CCCCCCCCEEEECCCCCCHHCCEEEECCCCEEECCEEEECCCCCCCCCCCCCCCEEEEEE
TSTGELAWNWDSGNPDETAPIGPNETYAVSSPNSWSIASADDKLGLIYLPMGNSTPDQLG
CCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCCEEECCCCCEEEEEEECCCCCHHHHC
MYRSPAEEKYATSVVALHIETGKVAWVQQFIHHDLWDMDTPAQPSLLDLQTKSGLQPALV
CCCCCCHHHHCEEEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEEHHHCCCCCEEE
VPTKQGDVYVLNRKTGEPIIPITEQPAPQGTIPEDYASPTQPSSALNFKPEKMTGAQMWG
EECCCCCEEEEECCCCCCEEECCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCHHCC
ATPIDQLICRIQFKKLRYEGQYTPPSIQGTLVYPGNFGVFNWGGVAVDPERQVMFAMPLD
CCCHHHHHHHHHHHHHEECCCCCCCCCEEEEEECCCCCEEECCCEEECCCCCEEEECCHH
LAFVSKLIPNDNQQDLGPVNTGEQGVSTNTGSPYSVSLSPFLSPLGIPCQQPPWGSVAGV
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHCCCCCCCCCCCCCCCCEEEE
NLRTGEKVWQHKNGTTRDMTALPLPIPLGMPGIGGPIITKGGVAFMAASLDDYLRGYDLK
EECCCHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCEEECCCCEEEHHHHHHHHHCCCCC
TGQVLWTARLPAGGQATPMTYLNSKGEQMVVQVAGGHGSLGTTLGDYVVAYKLEK
CCCEEEEEECCCCCCCCCHHEECCCCCEEEEEEECCCCCCCCHHCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2228962; 8419307; 8202364; 9278503; 8509415; 8554505 [H]