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The map label for this gene is xseA [H]

Identifier: 119946572

GI number: 119946572

Start: 3637580

End: 3638923

Strand: Direct

Name: xseA [H]

Synonym: Ping_2951

Alternate gene names: 119946572

Gene position: 3637580-3638923 (Clockwise)

Preceding gene: 119946567

Following gene: 119946580

Centisome position: 79.78

GC content: 44.05

Gene sequence:

>1344_bases
ATGAACATTTCTGAAAATAAAAATATTTATAGCGTCAGTTCACTCAATCGCGCGGCAAAGGCCCTTCTGGAAACGGGATT
GGGCGTTATTTGGTTATCGGGCGAAATTTCTAATTTAACCATTGCTGTTTCCGGCCATTGGTACTTCACCCTAAAAGATC
ACAGTGCACAGGTACGTTGTGCCATGTTTAAAGGTAATAATCGGCGTAGCGGTTTTACGCCTAAACATGGCCAGCAGGTT
TTAGTGCGCGCCAAACTTAGCCTTTATGAGGCACGCGGTGACTATCAGCTAATTATTGAAAGCATGGCACCTGAAGGTGA
TGGTCTATTAAAACAACAATTTGAAGCATTAAAATTTAAATTGGCCGCTGAAGGTTTATTTTCTGAAAGTCACAAAAAAC
CCCTGCCGCAGTTAATTAAATGTATTGGTATTATTACCTCATCAACGGGGGCTGCACTGCATGATATTCTCAGTATTTTA
AAACGTCGCGATCCCCGCCTGAAGGTAATTATCTATCCGTCGTTAGTCCAGGGTGCGAGCAGTGCAGCCTCGGTTGCTGC
GCAAATTAAGTTAGCCAATGCCCGTCATGAATGTGATTTATTAATTGTCGGTCGCGGCGGTGGTTCTCTGGAAGATTTAT
GGTGTTTTAATGAAGCGCTGGTGGCTTATGCAATATATGACAGTCAGTTGCCTATTATCAGTGCCGTTGGCCATGAAATT
GATGTCACTATTGCAGATTTTGTCGCCGATGTTCGCGCGGCAACCCCGTCAGCAGCGGCTGAGCTTGTTAGTCAGAATAA
AGCCTTTCACCAAACTCAATTAGATACCTTAACAAATCGCATGAAGCAGGCAATTCTGGCGCGCTTGCAGCTAAAATCAC
ATCAACATGCTTTAATCAGAGAAAAATTACTTAATCTCCACCCGAAGCATAAGCTCCAGCAACAGACCTTACAGTTAGAT
GAACTCAGCCTGCGCTTACAGCATGCTTTTCAGGCAACCATGAATCAAGCCAAACGAGATCTGCAAAGACTGCAAAGTGG
TTTATTTCAACATAGCCCAGAAGGCATTATTTCCGTCGAACAACAAAAACAGAAACAACTTCAGCACCGTTTAGAACATG
CTGTGCAGGTAACACTCAATCAGAAAACGACTTTACTACAAAATAAAAGCAGTCGACTCAATACCGTCAGCCCGCTGGCA
ACGCTGGCACGCGGTTATGCGATTGTAAAAGATAAGAACGGGAAAATCACCACGGATACGGCCATGCTGCAACCTGGGGA
TAAAATAGAGGTGCGTTTAGATAAGGGAGAATTTGAAGCACAAGTGCTAGGTGGCGAGCTGTAA

Upstream 100 bases:

>100_bases
AGTACAATTAAAAAATCACCTTAAGGGCAACTCTTTTTATCATTCCACCTAACTGTTAGAATCTAAATTAATTTTTACGG
GTAACTCATAGCGAAAAACC

Downstream 100 bases:

>100_bases
GGCCGAGAGGCTGAAAGGCTATAAAGCTATAAGGCTGAAAGCTTTCCAGCTTCGAGCCTTCGAGCTGAAAGCCGACAGCC
GACAGCCGAAAACTGACGGC

Product: exodeoxyribonuclease VII, large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MNISENKNIYSVSSLNRAAKALLETGLGVIWLSGEISNLTIAVSGHWYFTLKDHSAQVRCAMFKGNNRRSGFTPKHGQQV
LVRAKLSLYEARGDYQLIIESMAPEGDGLLKQQFEALKFKLAAEGLFSESHKKPLPQLIKCIGIITSSTGAALHDILSIL
KRRDPRLKVIIYPSLVQGASSAASVAAQIKLANARHECDLLIVGRGGGSLEDLWCFNEALVAYAIYDSQLPIISAVGHEI
DVTIADFVADVRAATPSAAAELVSQNKAFHQTQLDTLTNRMKQAILARLQLKSHQHALIREKLLNLHPKHKLQQQTLQLD
ELSLRLQHAFQATMNQAKRDLQRLQSGLFQHSPEGIISVEQQKQKQLQHRLEHAVQVTLNQKTTLLQNKSSRLNTVSPLA
TLARGYAIVKDKNGKITTDTAMLQPGDKIEVRLDKGEFEAQVLGGEL

Sequences:

>Translated_447_residues
MNISENKNIYSVSSLNRAAKALLETGLGVIWLSGEISNLTIAVSGHWYFTLKDHSAQVRCAMFKGNNRRSGFTPKHGQQV
LVRAKLSLYEARGDYQLIIESMAPEGDGLLKQQFEALKFKLAAEGLFSESHKKPLPQLIKCIGIITSSTGAALHDILSIL
KRRDPRLKVIIYPSLVQGASSAASVAAQIKLANARHECDLLIVGRGGGSLEDLWCFNEALVAYAIYDSQLPIISAVGHEI
DVTIADFVADVRAATPSAAAELVSQNKAFHQTQLDTLTNRMKQAILARLQLKSHQHALIREKLLNLHPKHKLQQQTLQLD
ELSLRLQHAFQATMNQAKRDLQRLQSGLFQHSPEGIISVEQQKQKQLQHRLEHAVQVTLNQKTTLLQNKSSRLNTVSPLA
TLARGYAIVKDKNGKITTDTAMLQPGDKIEVRLDKGEFEAQVLGGEL
>Mature_447_residues
MNISENKNIYSVSSLNRAAKALLETGLGVIWLSGEISNLTIAVSGHWYFTLKDHSAQVRCAMFKGNNRRSGFTPKHGQQV
LVRAKLSLYEARGDYQLIIESMAPEGDGLLKQQFEALKFKLAAEGLFSESHKKPLPQLIKCIGIITSSTGAALHDILSIL
KRRDPRLKVIIYPSLVQGASSAASVAAQIKLANARHECDLLIVGRGGGSLEDLWCFNEALVAYAIYDSQLPIISAVGHEI
DVTIADFVADVRAATPSAAAELVSQNKAFHQTQLDTLTNRMKQAILARLQLKSHQHALIREKLLNLHPKHKLQQQTLQLD
ELSLRLQHAFQATMNQAKRDLQRLQSGLFQHSPEGIISVEQQKQKQLQHRLEHAVQVTLNQKTTLLQNKSSRLNTVSPLA
TLARGYAIVKDKNGKITTDTAMLQPGDKIEVRLDKGEFEAQVLGGEL

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=439, Percent_Identity=49.2027334851936, Blast_Score=436, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 49412; Mature: 49412

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNISENKNIYSVSSLNRAAKALLETGLGVIWLSGEISNLTIAVSGHWYFTLKDHSAQVRC
CCCCCCCCEEEHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEEECEEEEEEECCCCEEEE
AMFKGNNRRSGFTPKHGQQVLVRAKLSLYEARGDYQLIIESMAPEGDGLLKQQFEALKFK
EEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHCCCCCCHHHHHHHHHHHH
LAAEGLFSESHKKPLPQLIKCIGIITSSTGAALHDILSILKRRDPRLKVIIYPSLVQGAS
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEHHHHCCCC
SAASVAAQIKLANARHECDLLIVGRGGGSLEDLWCFNEALVAYAIYDSQLPIISAVGHEI
HHHHHHHHEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHEEEEECCCCCCHHHCCCEE
DVTIADFVADVRAATPSAAAELVSQNKAFHQTQLDTLTNRMKQAILARLQLKSHQHALIR
EEEHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKLLNLHPKHKLQQQTLQLDELSLRLQHAFQATMNQAKRDLQRLQSGLFQHSPEGIISVE
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHH
QQKQKQLQHRLEHAVQVTLNQKTTLLQNKSSRLNTVSPLATLARGYAIVKDKNGKITTDT
HHHHHHHHHHHHHHHEEEECCCHHHHHCCCCCCCHHHHHHHHHCCEEEEECCCCEEEECE
AMLQPGDKIEVRLDKGEFEAQVLGGEL
EEECCCCEEEEEECCCCCEEEECCCCC
>Mature Secondary Structure
MNISENKNIYSVSSLNRAAKALLETGLGVIWLSGEISNLTIAVSGHWYFTLKDHSAQVRC
CCCCCCCCEEEHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEEECEEEEEEECCCCEEEE
AMFKGNNRRSGFTPKHGQQVLVRAKLSLYEARGDYQLIIESMAPEGDGLLKQQFEALKFK
EEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEHHHHHCCCCCCHHHHHHHHHHHH
LAAEGLFSESHKKPLPQLIKCIGIITSSTGAALHDILSILKRRDPRLKVIIYPSLVQGAS
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEHHHHCCCC
SAASVAAQIKLANARHECDLLIVGRGGGSLEDLWCFNEALVAYAIYDSQLPIISAVGHEI
HHHHHHHHEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHEEEEECCCCCCHHHCCCEE
DVTIADFVADVRAATPSAAAELVSQNKAFHQTQLDTLTNRMKQAILARLQLKSHQHALIR
EEEHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKLLNLHPKHKLQQQTLQLDELSLRLQHAFQATMNQAKRDLQRLQSGLFQHSPEGIISVE
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHH
QQKQKQLQHRLEHAVQVTLNQKTTLLQNKSSRLNTVSPLATLARGYAIVKDKNGKITTDT
HHHHHHHHHHHHHHHEEEECCCHHHHHCCCCCCCHHHHHHHHHCCEEEEECCCCEEEECE
AMLQPGDKIEVRLDKGEFEAQVLGGEL
EEECCCCEEEEEECCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA