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The map label for this gene is gntR [H]

Identifier: 119946550

GI number: 119946550

Start: 3614222

End: 3615232

Strand: Direct

Name: gntR [H]

Synonym: Ping_2929

Alternate gene names: 119946550

Gene position: 3614222-3615232 (Clockwise)

Preceding gene: 119946541

Following gene: 119946554

Centisome position: 79.27

GC content: 45.1

Gene sequence:

>1011_bases
ATGGATAATATTATGAGCAAGAAAAAAAGACCCACCCTGCAGGATGTTGCCAATATTGTTGGCGTGACCAAAATGACCGT
CAGTCGATACCTTCGCGACCCGTCTCTGGTCTCTTCTGCAATACAGGCTAAAATTGCAGTCGCATTAGAAGAATTGGGTT
ACATTCCCAACCGGGCACCGGATCTGCTCTCTCATGCTAAAAGCCATGCGATAGGCATCCTTGTTCCCTCTTTAACCAAT
CAGGTATTCTCTGAGGTTATCCGCGGTATTGAAAAAGTGACCAAAGCCGCAGGATACCAGACCATGTTGGCTCATTACGG
CTATAGCGCTGAGCTTGAAGAAGAACGAATTAGCTTCCTGCTATCCTATCATATTGATGGTTTAATTCTTTCTGACAGTT
ACCATACGGCCCGCACTTTAAAAATGATCAAAACGGCGGGTATTCCCGTTATTGAAATGATGGATGCCGCATCACCAGCT
ATTGAACAGGCTGTGGGTGTTGATAATCTCGAAGCCGGTTATCAGATGGTTTCAGCCATGATTGGTCGAGGTTATAAAAA
TATTGTTTATCTGGGGGCTCGTTTAGATGCACGTACCCAGTTTCGACAACAGGGTTATGAAAAAGCGATGCAGGAGCACG
GTTTAGTCGCTAAAAGTGTGATGACTGAAGCGCCTTCTTCCTTTACCTTAGGCGCTGAATTATTAACCCGGGCAATGGCT
GAGCATCCACAAACAGATGGTTTATTTTGTACCAATGATGATCTCGCGGTTGGGGCTATTTTTGAAGCACAGCGTTGCGG
CATTAAAATCCCCGATCAGATTGCCGTTGCCGGCTTTCATGGCCATAATGTTGGCCAATCTATGGTGCCTAAATTAGCAA
CGGTGATCACTCCCCGCGAAAAAATTGGCCAAGTAACGGCAGAGCAGCTTATTGCCCGATTAAATGGTCAAGCGATTAAA
CATAAAGTTATCGATCTGGGTTTTAAAATCCAACTGGGTGAAAGTATCTGA

Upstream 100 bases:

>100_bases
TTGTTCTATTAAAAGTTATTATTTTCCCGTTTATGCTTAAGATAAATGTAAGAAAAGTGGAATACAATATTAATTGTTGT
TATGTTACAGGTAACATTTA

Downstream 100 bases:

>100_bases
TTTTTGTTATCAAGACAGGCATCAATCAATGATATCTGCCCTGTTGTAACATAAATAATCTTAATAGCACTGCACTGTTG
ATCAATTAAGCCTTTAAGTT

Product: transcriptional regulator, periplasmic binding protein of LacI family protein

Products: NA

Alternate protein names: Gluconate utilization system GNT-I transcriptional repressor [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MDNIMSKKKRPTLQDVANIVGVTKMTVSRYLRDPSLVSSAIQAKIAVALEELGYIPNRAPDLLSHAKSHAIGILVPSLTN
QVFSEVIRGIEKVTKAAGYQTMLAHYGYSAELEEERISFLLSYHIDGLILSDSYHTARTLKMIKTAGIPVIEMMDAASPA
IEQAVGVDNLEAGYQMVSAMIGRGYKNIVYLGARLDARTQFRQQGYEKAMQEHGLVAKSVMTEAPSSFTLGAELLTRAMA
EHPQTDGLFCTNDDLAVGAIFEAQRCGIKIPDQIAVAGFHGHNVGQSMVPKLATVITPREKIGQVTAEQLIARLNGQAIK
HKVIDLGFKIQLGESI

Sequences:

>Translated_336_residues
MDNIMSKKKRPTLQDVANIVGVTKMTVSRYLRDPSLVSSAIQAKIAVALEELGYIPNRAPDLLSHAKSHAIGILVPSLTN
QVFSEVIRGIEKVTKAAGYQTMLAHYGYSAELEEERISFLLSYHIDGLILSDSYHTARTLKMIKTAGIPVIEMMDAASPA
IEQAVGVDNLEAGYQMVSAMIGRGYKNIVYLGARLDARTQFRQQGYEKAMQEHGLVAKSVMTEAPSSFTLGAELLTRAMA
EHPQTDGLFCTNDDLAVGAIFEAQRCGIKIPDQIAVAGFHGHNVGQSMVPKLATVITPREKIGQVTAEQLIARLNGQAIK
HKVIDLGFKIQLGESI
>Mature_336_residues
MDNIMSKKKRPTLQDVANIVGVTKMTVSRYLRDPSLVSSAIQAKIAVALEELGYIPNRAPDLLSHAKSHAIGILVPSLTN
QVFSEVIRGIEKVTKAAGYQTMLAHYGYSAELEEERISFLLSYHIDGLILSDSYHTARTLKMIKTAGIPVIEMMDAASPA
IEQAVGVDNLEAGYQMVSAMIGRGYKNIVYLGARLDARTQFRQQGYEKAMQEHGLVAKSVMTEAPSSFTLGAELLTRAMA
EHPQTDGLFCTNDDLAVGAIFEAQRCGIKIPDQIAVAGFHGHNVGQSMVPKLATVITPREKIGQVTAEQLIARLNGQAIK
HKVIDLGFKIQLGESI

Specific function: Negative regulator for the gluconate utilization system GNT-I, the gntUKR operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994940, Length=330, Percent_Identity=62.7272727272727, Blast_Score=447, Evalue=1e-127,
Organism=Escherichia coli, GI1790715, Length=331, Percent_Identity=44.1087613293051, Blast_Score=315, Evalue=2e-87,
Organism=Escherichia coli, GI1790369, Length=311, Percent_Identity=27.9742765273312, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1790194, Length=324, Percent_Identity=28.0864197530864, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789068, Length=318, Percent_Identity=28.3018867924528, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787906, Length=266, Percent_Identity=29.3233082706767, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787948, Length=307, Percent_Identity=24.7557003257329, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787580, Length=316, Percent_Identity=25.9493670886076, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1788474, Length=303, Percent_Identity=24.7524752475248, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1789202, Length=297, Percent_Identity=23.9057239057239, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786540, Length=315, Percent_Identity=23.1746031746032, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786268, Length=283, Percent_Identity=25.0883392226148, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1790689, Length=322, Percent_Identity=24.5341614906832, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36562; Mature: 36562

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNIMSKKKRPTLQDVANIVGVTKMTVSRYLRDPSLVSSAIQAKIAVALEELGYIPNRAP
CCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCH
DLLSHAKSHAIGILVPSLTNQVFSEVIRGIEKVTKAAGYQTMLAHYGYSAELEEERISFL
HHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LSYHIDGLILSDSYHTARTLKMIKTAGIPVIEMMDAASPAIEQAVGVDNLEAGYQMVSAM
HHHCCCCEEEECCCHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHH
IGRGYKNIVYLGARLDARTQFRQQGYEKAMQEHGLVAKSVMTEAPSSFTLGAELLTRAMA
HCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHH
EHPQTDGLFCTNDDLAVGAIFEAQRCGIKIPDQIAVAGFHGHNVGQSMVPKLATVITPRE
HCCCCCCEEECCCCCEEHHHHHHHHCCCCCCCHHEEEECCCCCCCHHHHHHHHHHCCCHH
KIGQVTAEQLIARLNGQAIKHKVIDLGFKIQLGESI
HHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEECCCC
>Mature Secondary Structure
MDNIMSKKKRPTLQDVANIVGVTKMTVSRYLRDPSLVSSAIQAKIAVALEELGYIPNRAP
CCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCH
DLLSHAKSHAIGILVPSLTNQVFSEVIRGIEKVTKAAGYQTMLAHYGYSAELEEERISFL
HHHHHHHHHEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
LSYHIDGLILSDSYHTARTLKMIKTAGIPVIEMMDAASPAIEQAVGVDNLEAGYQMVSAM
HHHCCCCEEEECCCHHHHHHHHHHHCCCCHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHH
IGRGYKNIVYLGARLDARTQFRQQGYEKAMQEHGLVAKSVMTEAPSSFTLGAELLTRAMA
HCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHH
EHPQTDGLFCTNDDLAVGAIFEAQRCGIKIPDQIAVAGFHGHNVGQSMVPKLATVITPRE
HCCCCCCEEECCCCCEEHHHHHHHHCCCCCCCHHEEEECCCCCCCHHHHHHHHHHCCCHH
KIGQVTAEQLIARLNGQAIKHKVIDLGFKIQLGESI
HHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]