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The map label for this gene is hmp [H]

Identifier: 119946528

GI number: 119946528

Start: 3586192

End: 3587382

Strand: Reverse

Name: hmp [H]

Synonym: Ping_2905

Alternate gene names: 119946528

Gene position: 3587382-3586192 (Counterclockwise)

Preceding gene: 119946529

Following gene: 119946527

Centisome position: 78.68

GC content: 44.42

Gene sequence:

>1191_bases
ATGTTAACGCAAACTGAAATTAATATAATTAAAGACAGCGCACCGGCACTCGCACAATACGGAGAAGATATTACCGGGCG
GTTTTATCAGATTCTATTTCAGTCTCACCCGGAATTAAGTCATATATTCAATATGACCAATCAGAAAAGTGGTAGTCAGA
AAGCCGCGTTAGCAACGGCTGTTTATGCATTTGCAAAATATGTCGATAATCTTGAAGTGATCTTAGGCGATGTCGAGCGT
ATTGCGCAAAAGCACGCCAGCTTGGGCATTAAAAGTGAACATTATCCTTTAGTCGGCAGCGCATTATTACAGGCGATTGA
CGAAATTCTACAGCCTCCGCAGTCAGTAATTGATGCCTGGGCAAAAGGTTACGGTATTTTAGCTGATGTTTTCATTAATC
GAGAACAGGCACTCTACGATCAGAAATCAGAGCAGCAGGGCGGCTGGAGGGGCACGCGGGAATTTACTCTCGTGAATAAA
GTCATGGAAACGCCTTTGATCACCTCGTTTTACTTAAAACCGAATGACGGTTTGGCCATTTCTGACTTTGTTCCCGGTCA
GTATATCGCCGTTCATATGCAGCCAGCGGGGGCTGAAAACCATCAAATTCGTCAATACAGTCTGTCAAGTGCCTATAATA
AAAACAGCTACCGAATCTCGGTAAAAAAAGAGCAGAGTCCGCATGGTGAGGGACTGATTTCAAACTACCTGCATGACAGT
GTCAATGTTGGCGATACGCTGAATCTGAGTAATCCCTTTGGCGAGTTTTATTTACAGGAAAGCAGCAATCCAGTGGTGCT
GATAAGCGGCGGTGTGGGCATTACTCCGATGCAGGCGATGCTTGAAACCTTAGTATCGGGCGGCTCCCGGGAGGTTCATT
TTGTTCACGGCGCGCTGAACAGCGAACATCATGCTTATAAAGAGATGCACAATAATATAACTGATACGGAGCAGGTAACA
ACGCATGTTTTTTATGAGCAGGCACCCGCTGAGCCGGCAGATAATCATTATCAGGGGCTTATTAATCTGGAACTATTAAA
ATCAGATTTACCGCTGAACAGTGCCGAATTTTACCTTTGCGGCCCGCTTGCCATGATGAAAGCCGTCTATAAACAGTTAA
AAACGTTACAAGTAGCGGATGAAAATATCTTCTATGAAGTATTTGGTGCGTCTAAAGCACTGGCGGAATAA

Upstream 100 bases:

>100_bases
CAAAGGTTTTATTTGGGTTTTATTTGCATCTTTTTAAATATGCATTTAAGATGCCTCTTAAATAAAAAGAAGTATTTTAA
ATGCATATTAAGGAGTTGAC

Downstream 100 bases:

>100_bases
AGGCCCGCTCATTTTTCTGCATAGCCCTTTTGCATCGTACTTTTGTATAGAAGATGGGCGCATTTACTTAGCATGTGTCA
CTGCAGAAAATTAAAGTATT

Product: fused nitric oxide dioxygenase and dihydropteridine reductase

Products: NA

Alternate protein names: Flavohemoglobin; Hemoglobin-like protein; Nitric oxide dioxygenase; NO oxygenase; NOD [H]

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MLTQTEINIIKDSAPALAQYGEDITGRFYQILFQSHPELSHIFNMTNQKSGSQKAALATAVYAFAKYVDNLEVILGDVER
IAQKHASLGIKSEHYPLVGSALLQAIDEILQPPQSVIDAWAKGYGILADVFINREQALYDQKSEQQGGWRGTREFTLVNK
VMETPLITSFYLKPNDGLAISDFVPGQYIAVHMQPAGAENHQIRQYSLSSAYNKNSYRISVKKEQSPHGEGLISNYLHDS
VNVGDTLNLSNPFGEFYLQESSNPVVLISGGVGITPMQAMLETLVSGGSREVHFVHGALNSEHHAYKEMHNNITDTEQVT
THVFYEQAPAEPADNHYQGLINLELLKSDLPLNSAEFYLCGPLAMMKAVYKQLKTLQVADENIFYEVFGASKALAE

Sequences:

>Translated_396_residues
MLTQTEINIIKDSAPALAQYGEDITGRFYQILFQSHPELSHIFNMTNQKSGSQKAALATAVYAFAKYVDNLEVILGDVER
IAQKHASLGIKSEHYPLVGSALLQAIDEILQPPQSVIDAWAKGYGILADVFINREQALYDQKSEQQGGWRGTREFTLVNK
VMETPLITSFYLKPNDGLAISDFVPGQYIAVHMQPAGAENHQIRQYSLSSAYNKNSYRISVKKEQSPHGEGLISNYLHDS
VNVGDTLNLSNPFGEFYLQESSNPVVLISGGVGITPMQAMLETLVSGGSREVHFVHGALNSEHHAYKEMHNNITDTEQVT
THVFYEQAPAEPADNHYQGLINLELLKSDLPLNSAEFYLCGPLAMMKAVYKQLKTLQVADENIFYEVFGASKALAE
>Mature_396_residues
MLTQTEINIIKDSAPALAQYGEDITGRFYQILFQSHPELSHIFNMTNQKSGSQKAALATAVYAFAKYVDNLEVILGDVER
IAQKHASLGIKSEHYPLVGSALLQAIDEILQPPQSVIDAWAKGYGILADVFINREQALYDQKSEQQGGWRGTREFTLVNK
VMETPLITSFYLKPNDGLAISDFVPGQYIAVHMQPAGAENHQIRQYSLSSAYNKNSYRISVKKEQSPHGEGLISNYLHDS
VNVGDTLNLSNPFGEFYLQESSNPVVLISGGVGITPMQAMLETLVSGGSREVHFVHGALNSEHHAYKEMHNNITDTEQVT
THVFYEQAPAEPADNHYQGLINLELLKSDLPLNSAEFYLCGPLAMMKAVYKQLKTLQVADENIFYEVFGASKALAE

Specific function: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a centra

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1788903, Length=400, Percent_Identity=42.75, Blast_Score=330, Evalue=7e-92,
Organism=Escherichia coli, GI1788104, Length=230, Percent_Identity=29.1304347826087, Blast_Score=79, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6321673, Length=409, Percent_Identity=37.6528117359413, Blast_Score=229, Evalue=7e-61,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR012292
- InterPro:   IPR009050
- InterPro:   IPR000971
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00042 Globin; PF00175 NAD_binding_1 [H]

EC number: =1.14.12.17 [H]

Molecular weight: Translated: 43917; Mature: 43917

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS01033 GLOBIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTQTEINIIKDSAPALAQYGEDITGRFYQILFQSHPELSHIFNMTNQKSGSQKAALATA
CCCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHH
VYAFAKYVDNLEVILGDVERIAQKHASLGIKSEHYPLVGSALLQAIDEILQPPQSVIDAW
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHH
AKGYGILADVFINREQALYDQKSEQQGGWRGTREFTLVNKVMETPLITSFYLKPNDGLAI
HCCCCCHHHHHHCCHHHHHCCCHHCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCEEE
SDFVPGQYIAVHMQPAGAENHQIRQYSLSSAYNKNSYRISVKKEQSPHGEGLISNYLHDS
ECCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHCC
VNVGDTLNLSNPFGEFYLQESSNPVVLISGGVGITPMQAMLETLVSGGSREVHFVHGALN
CCCCCEECCCCCCCHHEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEECCCC
SEHHAYKEMHNNITDTEQVTTHVFYEQAPAEPADNHYQGLINLELLKSDLPLNSAEFYLC
CCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHCEEEEEEECCCCCCCCCCEEEE
GPLAMMKAVYKQLKTLQVADENIFYEVFGASKALAE
CHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHCC
>Mature Secondary Structure
MLTQTEINIIKDSAPALAQYGEDITGRFYQILFQSHPELSHIFNMTNQKSGSQKAALATA
CCCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHH
VYAFAKYVDNLEVILGDVERIAQKHASLGIKSEHYPLVGSALLQAIDEILQPPQSVIDAW
HHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHH
AKGYGILADVFINREQALYDQKSEQQGGWRGTREFTLVNKVMETPLITSFYLKPNDGLAI
HCCCCCHHHHHHCCHHHHHCCCHHCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCEEE
SDFVPGQYIAVHMQPAGAENHQIRQYSLSSAYNKNSYRISVKKEQSPHGEGLISNYLHDS
ECCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHCC
VNVGDTLNLSNPFGEFYLQESSNPVVLISGGVGITPMQAMLETLVSGGSREVHFVHGALN
CCCCCEECCCCCCCHHEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEEECCCC
SEHHAYKEMHNNITDTEQVTTHVFYEQAPAEPADNHYQGLINLELLKSDLPLNSAEFYLC
CCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHCEEEEEEECCCCCCCCCCEEEE
GPLAMMKAVYKQLKTLQVADENIFYEVFGASKALAE
CHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA