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The map label for this gene is yghU [H]

Identifier: 119946525

GI number: 119946525

Start: 3582771

End: 3583628

Strand: Direct

Name: yghU [H]

Synonym: Ping_2902

Alternate gene names: 119946525

Gene position: 3582771-3583628 (Clockwise)

Preceding gene: 119946524

Following gene: 119946533

Centisome position: 78.58

GC content: 43.36

Gene sequence:

>858_bases
ATGGAAAGGGAATACACTCCAGCAAAGGTTTGGACCCATAACAGTGAAAACGGGGGTACTTGGGCAAAGATAAACCGCCC
AATATCAGGGGCAACACATGATAAAGCCCTTCCTGTCGGCGTTCACCCTTTGCAGCTTTATTCTATGGGAACACCCAATG
GTCAGAAAGTCACTATTATGCTTGAAGAACTTCTGGCTTTAGGTATTTCAGAGGCTGAGTATGATGCTCATCTTATTGAC
ATTAGTGAAGGGCAACAATTCTCTTCCGGTTTTGTAGCAATTAATCCAAATTCTAAAATTCCAGCCTTATTGGATAGTTC
CACCGATAAACCCGTTCCCTTGTTCGAGTCTGGTTCAATCCTCCTGTATCTAGCTGAAAAGTTTGGGTGTCTTTTACCAG
AAAAACTTGAAGAACGCGCCAATGTATTCAACTGGTTATTTTGGTTACAAGGCGCTTCACCTTATTTAGGCGGTGGGTTT
GGTCATTTTTATGCTTATGCACCAGAGAAATTAGAGTATCCCATTGACCGTTTTACTATGGAAGTTAAACGTCAGCTTGA
TCTGCTCGACAAACAATTAGCTGAAAAGCATTTTATCGCAGGTGATCAATACAGTATTGCAGATATCGCTATCTGGCCAT
GGTATGGAAACTTAGTATTAGGCAAGCTCTATGGCGCAGCCGAATTTTTGGATGTTAATAGCTACAAAAATGTTCAGCGC
TGGGCAAAAGAAATAGCACAGCGCCCGGCAGTACAGCGCGGAAGAATAGTAAACCGCACCTGGGGAGAACCTTGGGAGCA
GGTTAGCGAACGCCACAATGCATCTGACATAAACGATGCGCTCAATCAAAAAAGCTAG

Upstream 100 bases:

>100_bases
TTGATCAATGAATTTTAACCAGTTAGCATGAAGGAATATGAACGAATGTTCAATTGATTCTTTACAATATAAAATACAAC
TAGTTGTATGAGGAGATACT

Downstream 100 bases:

>100_bases
AAAGTCAGCAGATCTTTACATGCTATTGTAAAGATCTGCTAAATTTTTCCCTATTTTGATTATTAAGAAGTATAAACATT
AGATAAGACTGCCCGTTTTA

Product: putative glutathione S-transferase YghU

Products: HX; R-S-glutathione

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MEREYTPAKVWTHNSENGGTWAKINRPISGATHDKALPVGVHPLQLYSMGTPNGQKVTIMLEELLALGISEAEYDAHLID
ISEGQQFSSGFVAINPNSKIPALLDSSTDKPVPLFESGSILLYLAEKFGCLLPEKLEERANVFNWLFWLQGASPYLGGGF
GHFYAYAPEKLEYPIDRFTMEVKRQLDLLDKQLAEKHFIAGDQYSIADIAIWPWYGNLVLGKLYGAAEFLDVNSYKNVQR
WAKEIAQRPAVQRGRIVNRTWGEPWEQVSERHNASDINDALNQKS

Sequences:

>Translated_285_residues
MEREYTPAKVWTHNSENGGTWAKINRPISGATHDKALPVGVHPLQLYSMGTPNGQKVTIMLEELLALGISEAEYDAHLID
ISEGQQFSSGFVAINPNSKIPALLDSSTDKPVPLFESGSILLYLAEKFGCLLPEKLEERANVFNWLFWLQGASPYLGGGF
GHFYAYAPEKLEYPIDRFTMEVKRQLDLLDKQLAEKHFIAGDQYSIADIAIWPWYGNLVLGKLYGAAEFLDVNSYKNVQR
WAKEIAQRPAVQRGRIVNRTWGEPWEQVSERHNASDINDALNQKS
>Mature_285_residues
MEREYTPAKVWTHNSENGGTWAKINRPISGATHDKALPVGVHPLQLYSMGTPNGQKVTIMLEELLALGISEAEYDAHLID
ISEGQQFSSGFVAINPNSKIPALLDSSTDKPVPLFESGSILLYLAEKFGCLLPEKLEERANVFNWLFWLQGASPYLGGGF
GHFYAYAPEKLEYPIDRFTMEVKRQLDLLDKQLAEKHFIAGDQYSIADIAIWPWYGNLVLGKLYGAAEFLDVNSYKNVQR
WAKEIAQRPAVQRGRIVNRTWGEPWEQVSERHNASDINDALNQKS

Specific function: Unknown

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI87082195, Length=283, Percent_Identity=68.1978798586572, Blast_Score=406, Evalue=1e-115,
Organism=Escherichia coli, GI1788640, Length=212, Percent_Identity=40.0943396226415, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI87081789, Length=175, Percent_Identity=30.2857142857143, Blast_Score=71, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6324100, Length=252, Percent_Identity=27.3809523809524, Blast_Score=93, Evalue=4e-20,
Organism=Drosophila melanogaster, GI28571670, Length=221, Percent_Identity=28.0542986425339, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI17864592, Length=234, Percent_Identity=28.6324786324786, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17864594, Length=217, Percent_Identity=27.6497695852535, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: 2.5.1.18

Molecular weight: Translated: 32112; Mature: 32112

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEREYTPAKVWTHNSENGGTWAKINRPISGATHDKALPVGVHPLQLYSMGTPNGQKVTIM
CCCCCCCCEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEE
LEELLALGISEAEYDAHLIDISEGQQFSSGFVAINPNSKIPALLDSSTDKPVPLFESGSI
HHHHHHCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCCEEECCCCCCCCCEECCCCE
LLYLAEKFGCLLPEKLEERANVFNWLFWLQGASPYLGGGFGHFYAYAPEKLEYPIDRFTM
EEEEEHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHEEECCHHHCCCHHHHHH
EVKRQLDLLDKQLAEKHFIAGDQYSIADIAIWPWYGNLVLGKLYGAAEFLDVNSYKNVQR
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHCCHHEEECCCHHHHHH
WAKEIAQRPAVQRGRIVNRTWGEPWEQVSERHNASDINDALNQKS
HHHHHHHCCCHHCCCEECCCCCCHHHHHHHHCCHHHHHHHHCCCC
>Mature Secondary Structure
MEREYTPAKVWTHNSENGGTWAKINRPISGATHDKALPVGVHPLQLYSMGTPNGQKVTIM
CCCCCCCCEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEE
LEELLALGISEAEYDAHLIDISEGQQFSSGFVAINPNSKIPALLDSSTDKPVPLFESGSI
HHHHHHCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCCEEECCCCCCCCCEECCCCE
LLYLAEKFGCLLPEKLEERANVFNWLFWLQGASPYLGGGFGHFYAYAPEKLEYPIDRFTM
EEEEEHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHEEECCHHHCCCHHHHHH
EVKRQLDLLDKQLAEKHFIAGDQYSIADIAIWPWYGNLVLGKLYGAAEFLDVNSYKNVQR
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHCCHHEEECCCHHHHHH
WAKEIAQRPAVQRGRIVNRTWGEPWEQVSERHNASDINDALNQKS
HHHHHHHCCCHHCCCEECCCCCCHHHHHHHHCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; glutathione

Specific reaction: RX + glutathione = HX + R-S-glutathione

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]