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The map label for this gene is hadL [H]

Identifier: 119946524

GI number: 119946524

Start: 3581812

End: 3582489

Strand: Direct

Name: hadL [H]

Synonym: Ping_2901

Alternate gene names: 119946524

Gene position: 3581812-3582489 (Clockwise)

Preceding gene: 119946519

Following gene: 119946525

Centisome position: 78.56

GC content: 42.18

Gene sequence:

>678_bases
ATGTCAGTGATACTTGCTTTTGATGTCTATGGAACATTAATTAATACACATGGAATAGTGACTATTTTAGAAAAATGGTT
AGGTAAAAATGCACAGGCTTTCTCTCAGACTTGGCGAGATAAACAACTGGAATACTCTTTCCGCAGGGGATTAATGCAGA
ATTACCAAAGCTTTGCAGTTTGCACCCGTCATGCTTTGGACTATACCTGTAATTTCTATCGGGTTTCACTTTCAAAAGAG
CAGAAGCAAGCGTTGATGGACGGTTATAAAACCCTGCCAGCCTTTGATGATGCAGCAAATGCGTTAGCGCAATTAAAGGG
TGCCGGCTTTAAACTTTATGCCTTTTCTAATGGCACTAAAGAAGCCGTTGAAGAGCTGCTTACCGGTGCAGGAATAAGGG
CGTTTTTCGATGGAATTGTCAGTTGCGATGATCTTAAATCATTTAAACCTAATCCAGCTGTCTACTGCCATTTTTTACGA
GAATCAGGTGCTAAACACAACCAGGCATGGCTAATATCAAGCAATCCCTTTGATGTAATTGGCGCAATATCAACAGGGAT
GCTGTCTGCATGGGTACAGCGTTCTCAGGATGCCATTTTTGATCCCTGGGATGTTGATCCAACGGCGATTATTACAAGCC
TTAAAGAGCTTAAAGGCGTGCTACCCAAGCCGGACTAA

Upstream 100 bases:

>100_bases
ATAAGCGCTTATTAGCGTTAATCTTCCCCTAGACAGAACGCTCTTAATTCCTCAACAAGAGGTAATTCAAGACCACTAAT
CACAATTTCAGGAGATAAAA

Downstream 100 bases:

>100_bases
AACACAGAATCCAGCTTTTGATACTTGTGCCGGGCTCTGCCTCTAATACCATCTAATTTCACATTTATTGCCAAATAGGC
GAATTTTTAGCCTCTCGCAT

Product: L-2-haloalkanoic acid dehalogenase, HAD superfamily protein

Products: NA

Alternate protein names: 2-haloalkanoic acid dehalogenase; Halocarboxylic acid halidohydrolase; L-2-haloacid dehalogenase [H]

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MSVILAFDVYGTLINTHGIVTILEKWLGKNAQAFSQTWRDKQLEYSFRRGLMQNYQSFAVCTRHALDYTCNFYRVSLSKE
QKQALMDGYKTLPAFDDAANALAQLKGAGFKLYAFSNGTKEAVEELLTGAGIRAFFDGIVSCDDLKSFKPNPAVYCHFLR
ESGAKHNQAWLISSNPFDVIGAISTGMLSAWVQRSQDAIFDPWDVDPTAIITSLKELKGVLPKPD

Sequences:

>Translated_225_residues
MSVILAFDVYGTLINTHGIVTILEKWLGKNAQAFSQTWRDKQLEYSFRRGLMQNYQSFAVCTRHALDYTCNFYRVSLSKE
QKQALMDGYKTLPAFDDAANALAQLKGAGFKLYAFSNGTKEAVEELLTGAGIRAFFDGIVSCDDLKSFKPNPAVYCHFLR
ESGAKHNQAWLISSNPFDVIGAISTGMLSAWVQRSQDAIFDPWDVDPTAIITSLKELKGVLPKPD
>Mature_224_residues
SVILAFDVYGTLINTHGIVTILEKWLGKNAQAFSQTWRDKQLEYSFRRGLMQNYQSFAVCTRHALDYTCNFYRVSLSKEQ
KQALMDGYKTLPAFDDAANALAQLKGAGFKLYAFSNGTKEAVEELLTGAGIRAFFDGIVSCDDLKSFKPNPAVYCHFLRE
SGAKHNQAWLISSNPFDVIGAISTGMLSAWVQRSQDAIFDPWDVDPTAIITSLKELKGVLPKPD

Specific function: Catalyzes the hydrolytic dehalogenation of small (S)-2- haloalkanoic acids to yield the corresponding (R)-2- hydroxyalkanoic acids. Acts on acids of short chain lengths, C(2) to C(4), with inversion of configuration at C-2 [H]

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. S-2- haloalkanoic acid dehalogenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006388
- InterPro:   IPR006328
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.8.1.2 [H]

Molecular weight: Translated: 25080; Mature: 24949

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVILAFDVYGTLINTHGIVTILEKWLGKNAQAFSQTWRDKQLEYSFRRGLMQNYQSFAV
CEEEEEEHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CTRHALDYTCNFYRVSLSKEQKQALMDGYKTLPAFDDAANALAQLKGAGFKLYAFSNGTK
HHHHHHHHEEEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCCH
EAVEELLTGAGIRAFFDGIVSCDDLKSFKPNPAVYCHFLRESGAKHNQAWLISSNPFDVI
HHHHHHHHCCCHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCHHH
GAISTGMLSAWVQRSQDAIFDPWDVDPTAIITSLKELKGVLPKPD
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SVILAFDVYGTLINTHGIVTILEKWLGKNAQAFSQTWRDKQLEYSFRRGLMQNYQSFAV
EEEEEEHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CTRHALDYTCNFYRVSLSKEQKQALMDGYKTLPAFDDAANALAQLKGAGFKLYAFSNGTK
HHHHHHHHEEEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEEECCCCH
EAVEELLTGAGIRAFFDGIVSCDDLKSFKPNPAVYCHFLRESGAKHNQAWLISSNPFDVI
HHHHHHHHCCCHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCHHH
GAISTGMLSAWVQRSQDAIFDPWDVDPTAIITSLKELKGVLPKPD
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1588303; 1556080 [H]