Click here to switch to the map view.

The map label for this gene is htpX [H]

Identifier: 119946523

GI number: 119946523

Start: 3580185

End: 3581036

Strand: Reverse

Name: htpX [H]

Synonym: Ping_2900

Alternate gene names: 119946523

Gene position: 3581036-3580185 (Counterclockwise)

Preceding gene: 119946526

Following gene: 119946522

Centisome position: 78.54

GC content: 44.13

Gene sequence:

>852_bases
ATGAAACGCATCTTGCTGTTTATTGCGACCAACTTTGCAATACTTATTGTACTCGGTATTGTTCTTAATATTGTATTACC
ATTGATGGGGATTCATCTGCAAGATACAGGCGGGCTGTTAATGATTTCTGCTGTATTTGGTTTGGGGGGCTCTTTTATTT
CTTTGGCGATATCCAAGTGGATTGCAAAACGAAGTGTGGGTGCTTATGTAATAGAGGAGCCGCGTAATGCACAGGAGGAG
TGGTTATTAAAGACCGTTAAAAGACAGGCTGTAAAAGCAGGTGTCGGCATGCCGGAAGTCGCTATCTATGACTCTCCTGA
CATTAATGCCTTTGCGACTGGTATGAATAAAAATAATGCCCTGGTGGCGGTGAGCAGCGGTTTATTGGGCAATATGACGG
CAGACGAAGCAGAAGCTGTGCTCGGACATGAAATGAGCCATATCGCTAACGGTGATATGGTTACTATGACCTTGCTTCAG
GGGGTAATGAATACCTTTGTATTTTTCTTTGCGCGGATAGTCGCACGGGCGGTAAGCAGGGGCAGTGACAATCAGTTTTT
CTACTTTATGACGGTTATGGCGTTTCAGATAATATTCGGTATGTTGGCCAGCATCATAGTGATGTGGTTTTCCCGTTATC
GTGAATTCCGTGCCGATGCTGGCGGTGCGAATTTAGCGGGTAGAGAAAAAATGATCAATGCCTTAAAGCGCTTACAAAGA
AATAAACTCGAAAGTCAGCTTAATGGTCAGTTAGTTGCCTTTGGTATCAGTGGTAAGCAAGCGTTTTCTGAGCTGCTGAT
GAGTCATCCCCCGCTTGAAAAAAGAATTAAGGCTTTACAAAGGCAAGCGTAG

Upstream 100 bases:

>100_bases
AAACTGTTTTGATAGCATTGCAGATTGCTCTAGATAGTGAAGCAATCTAAGCTTTGATGGTATCTGTTGTTGAACCTTTG
AAATATGACTGGGAGAGTTT

Downstream 100 bases:

>100_bases
GGCGGTCGCATCACTGCACAATCGCTGGTGTTATGTGCACCATAACAGGCAGAAGCAGATGATCTGATTGATGATTGCTT
ATCCGATACTCTCGTGTATT

Product: peptidase M48, Ste24p

Products: NA

Alternate protein names: Heat shock protein HtpX [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MKRILLFIATNFAILIVLGIVLNIVLPLMGIHLQDTGGLLMISAVFGLGGSFISLAISKWIAKRSVGAYVIEEPRNAQEE
WLLKTVKRQAVKAGVGMPEVAIYDSPDINAFATGMNKNNALVAVSSGLLGNMTADEAEAVLGHEMSHIANGDMVTMTLLQ
GVMNTFVFFFARIVARAVSRGSDNQFFYFMTVMAFQIIFGMLASIIVMWFSRYREFRADAGGANLAGREKMINALKRLQR
NKLESQLNGQLVAFGISGKQAFSELLMSHPPLEKRIKALQRQA

Sequences:

>Translated_283_residues
MKRILLFIATNFAILIVLGIVLNIVLPLMGIHLQDTGGLLMISAVFGLGGSFISLAISKWIAKRSVGAYVIEEPRNAQEE
WLLKTVKRQAVKAGVGMPEVAIYDSPDINAFATGMNKNNALVAVSSGLLGNMTADEAEAVLGHEMSHIANGDMVTMTLLQ
GVMNTFVFFFARIVARAVSRGSDNQFFYFMTVMAFQIIFGMLASIIVMWFSRYREFRADAGGANLAGREKMINALKRLQR
NKLESQLNGQLVAFGISGKQAFSELLMSHPPLEKRIKALQRQA
>Mature_283_residues
MKRILLFIATNFAILIVLGIVLNIVLPLMGIHLQDTGGLLMISAVFGLGGSFISLAISKWIAKRSVGAYVIEEPRNAQEE
WLLKTVKRQAVKAGVGMPEVAIYDSPDINAFATGMNKNNALVAVSSGLLGNMTADEAEAVLGHEMSHIANGDMVTMTLLQ
GVMNTFVFFFARIVARAVSRGSDNQFFYFMTVMAFQIIFGMLASIIVMWFSRYREFRADAGGANLAGREKMINALKRLQR
NKLESQLNGQLVAFGISGKQAFSELLMSHPPLEKRIKALQRQA

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=292, Percent_Identity=54.1095890410959, Blast_Score=313, Evalue=9e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 31078; Mature: 31078

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRILLFIATNFAILIVLGIVLNIVLPLMGIHLQDTGGLLMISAVFGLGGSFISLAISKW
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHCCHHHHHHHHHHH
IAKRSVGAYVIEEPRNAQEEWLLKTVKRQAVKAGVGMPEVAIYDSPDINAFATGMNKNNA
HHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEECCCCCCE
LVAVSSGLLGNMTADEAEAVLGHEMSHIANGDMVTMTLLQGVMNTFVFFFARIVARAVSR
EEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GSDNQFFYFMTVMAFQIIFGMLASIIVMWFSRYREFRADAGGANLAGREKMINALKRLQR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
NKLESQLNGQLVAFGISGKQAFSELLMSHPPLEKRIKALQRQA
HHHHHHHCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MKRILLFIATNFAILIVLGIVLNIVLPLMGIHLQDTGGLLMISAVFGLGGSFISLAISKW
CCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHCCHHHHHHHHHHH
IAKRSVGAYVIEEPRNAQEEWLLKTVKRQAVKAGVGMPEVAIYDSPDINAFATGMNKNNA
HHHHCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEEECCCCCCE
LVAVSSGLLGNMTADEAEAVLGHEMSHIANGDMVTMTLLQGVMNTFVFFFARIVARAVSR
EEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GSDNQFFYFMTVMAFQIIFGMLASIIVMWFSRYREFRADAGGANLAGREKMINALKRLQR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
NKLESQLNGQLVAFGISGKQAFSELLMSHPPLEKRIKALQRQA
HHHHHHHCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA