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The map label for this gene is murA

Identifier: 119946504

GI number: 119946504

Start: 3562049

End: 3563308

Strand: Reverse

Name: murA

Synonym: Ping_2881

Alternate gene names: 119946504

Gene position: 3563308-3562049 (Counterclockwise)

Preceding gene: 119946505

Following gene: 119946501

Centisome position: 78.15

GC content: 43.73

Gene sequence:

>1260_bases
ATGGGTCAGTTTTTAATTCAAGGTGGTTGCCAATTAAAAGGGGAGGTGACAATATCCGGTGCCAAAAATGCTGCATTACC
AATTCTATTTGCGAGCTTATTATCAAAAGGTAATGTGAATTTAACGAATGTCCCGCTGTTAAAAGATATCTCGACAACAC
TTGAGCTTTTAAAAGAATTAGGTGCAGAAGCATCACAAGATGGACATGAAGTACATATTAATGCTTCATCGGTGAAAAAC
TATACCGCTTCCTATGAGTTAGTACGCAGTATGCGTGCGTCTATTTTGGCGCTAGGCCCTTTAGTTGCCCGTTTTGGTGA
AGCCGATATCTCATTACCTGGGGGCTGTGCTATTGGCGCTCGCCCGGTTAATCTGCATATCCATGGTTTAGAGCAGATGG
GGGCAATCATTAAAGTGCAGAATGGCTTTATTAAAGCGCGTGTTAATGGGCGTTTAAAGGGTGCACATTTGTACATGGAT
ATGGTCAGTGTTACCGGCACGGGTAATTTAATGATGGCAGCGGCGCTTGCTGAGGGTGTTACGACCATCGAAAATGCAGC
GAAAGAACCTGAACTTGTTGATCTGGCTAACTTTATTAATGGTATGGGTGGCAAGATTTCAGGCGCAGGAACAGATACTT
TAACAATTGAAGGTGTTGAGTCTTTGGGTGATTGTAGCTATCAGGTGCAGCCGGATCGCATTGAGACGGGGACTTTTTTA
GTGGCAGGTGTGGTAAGTGGTGGTAAAGTTAAGTGTCTTAAAACCGCCCCGCATTTATTAACGGCTGTACTGTCTAAATT
AGAAGAAGCGGGTGCCGCAGTGACAACGGGCAGTGATTGGATTGAGGTTGATATGATTGATCGTCAATTGAAATCAGTGA
ATATCTCAACGGCTCCGCATCCTGCATTCCCAACGGATATGCAGGCACAATTTACGGTGTTAAATACCGTTGCTCCCGGC
ACGGGACGAATCAAAGAAAACATTTTTGAAAATCGTTTTATGCATGTGCCTGAATTACAACGAATGGGCGCAAATATTAT
ATTGGAAGGTAATCTTGCCATTTGTGGTGATCCTGATCCGCTGTGTGGCGCAGAAGTGATGGCGACAGATTTACGTGCAT
CGGCAAGTTTAGTGATTGCAGGCTTAATCGCCGAGGGTGAAACGATTGTTGATGAGATTTACCACATTGACCGGGGTTAT
GAAGCAATAGAAAATAAGTTGATTGCGCTGGGTGCAAAGATTAAGCGTATTGAAAATTAA

Upstream 100 bases:

>100_bases
ATAGCAAGTAATGCCATTCATGCTCTCAGCATTAAAGCCTTAACACCCGATGAGTGGCAAAAACAAAAGCATTTTATTTA
AAAGAGATAAGGACAATTTA

Downstream 100 bases:

>100_bases
CGTTAATTCATTTTTTACAGGCTGTTTTGATGCTGTGAATAACAAAAAAAGGGAAGCTTAGTGCTTCCCTTTTTTTTGTT
CTATTAAGGGTTAATTTCTT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MGQFLIQGGCQLKGEVTISGAKNAALPILFASLLSKGNVNLTNVPLLKDISTTLELLKELGAEASQDGHEVHINASSVKN
YTASYELVRSMRASILALGPLVARFGEADISLPGGCAIGARPVNLHIHGLEQMGAIIKVQNGFIKARVNGRLKGAHLYMD
MVSVTGTGNLMMAAALAEGVTTIENAAKEPELVDLANFINGMGGKISGAGTDTLTIEGVESLGDCSYQVQPDRIETGTFL
VAGVVSGGKVKCLKTAPHLLTAVLSKLEEAGAAVTTGSDWIEVDMIDRQLKSVNISTAPHPAFPTDMQAQFTVLNTVAPG
TGRIKENIFENRFMHVPELQRMGANIILEGNLAICGDPDPLCGAEVMATDLRASASLVIAGLIAEGETIVDEIYHIDRGY
EAIENKLIALGAKIKRIEN

Sequences:

>Translated_419_residues
MGQFLIQGGCQLKGEVTISGAKNAALPILFASLLSKGNVNLTNVPLLKDISTTLELLKELGAEASQDGHEVHINASSVKN
YTASYELVRSMRASILALGPLVARFGEADISLPGGCAIGARPVNLHIHGLEQMGAIIKVQNGFIKARVNGRLKGAHLYMD
MVSVTGTGNLMMAAALAEGVTTIENAAKEPELVDLANFINGMGGKISGAGTDTLTIEGVESLGDCSYQVQPDRIETGTFL
VAGVVSGGKVKCLKTAPHLLTAVLSKLEEAGAAVTTGSDWIEVDMIDRQLKSVNISTAPHPAFPTDMQAQFTVLNTVAPG
TGRIKENIFENRFMHVPELQRMGANIILEGNLAICGDPDPLCGAEVMATDLRASASLVIAGLIAEGETIVDEIYHIDRGY
EAIENKLIALGAKIKRIEN
>Mature_418_residues
GQFLIQGGCQLKGEVTISGAKNAALPILFASLLSKGNVNLTNVPLLKDISTTLELLKELGAEASQDGHEVHINASSVKNY
TASYELVRSMRASILALGPLVARFGEADISLPGGCAIGARPVNLHIHGLEQMGAIIKVQNGFIKARVNGRLKGAHLYMDM
VSVTGTGNLMMAAALAEGVTTIENAAKEPELVDLANFINGMGGKISGAGTDTLTIEGVESLGDCSYQVQPDRIETGTFLV
AGVVSGGKVKCLKTAPHLLTAVLSKLEEAGAAVTTGSDWIEVDMIDRQLKSVNISTAPHPAFPTDMQAQFTVLNTVAPGT
GRIKENIFENRFMHVPELQRMGANIILEGNLAICGDPDPLCGAEVMATDLRASASLVIAGLIAEGETIVDEIYHIDRGYE
AIENKLIALGAKIKRIEN

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=418, Percent_Identity=63.1578947368421, Blast_Score=535, Evalue=1e-153,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_PSYIN (A1SYM0)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_944184.1
- ProteinModelPortal:   A1SYM0
- SMR:   A1SYM0
- STRING:   A1SYM0
- GeneID:   4626217
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_2881
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   ICGDTDG
- PhylomeDB:   A1SYM0
- BioCyc:   PING357804:PING_2881-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44193; Mature: 44061

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: ACT_SITE 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQFLIQGGCQLKGEVTISGAKNAALPILFASLLSKGNVNLTNVPLLKDISTTLELLKEL
CCCEEEECCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHH
GAEASQDGHEVHINASSVKNYTASYELVRSMRASILALGPLVARFGEADISLPGGCAIGA
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECC
RPVNLHIHGLEQMGAIIKVQNGFIKARVNGRLKGAHLYMDMVSVTGTGNLMMAAALAEGV
EEEEEEEECHHHCCCEEEEECCEEEEEECCEEEEEEEEEEEEEECCCCCHHHHHHHHHHH
TTIENAAKEPELVDLANFINGMGGKISGAGTDTLTIEGVESLGDCSYQVQPDRIETGTFL
HHHHHHCCCCCHHHHHHHHCCCCCEECCCCCCEEEEECCCCCCCCCEEECCCCCCCCCEE
VAGVVSGGKVKCLKTAPHLLTAVLSKLEEAGAAVTTGSDWIEVDMIDRQLKSVNISTAPH
EEEECCCCEEEEEECCHHHHHHHHHHHHHCCCEEECCCCEEEEEHHHHHHHHCCCCCCCC
PAFPTDMQAQFTVLNTVAPGTGRIKENIFENRFMHVPELQRMGANIILEGNLAICGDPDP
CCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHCCCCEEEECCEEEECCCCC
LCGAEVMATDLRASASLVIAGLIAEGETIVDEIYHIDRGYEAIENKLIALGAKIKRIEN
CCCHHHHHHHHHCCCCEEEEEEHHCCHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHCCC
>Mature Secondary Structure 
GQFLIQGGCQLKGEVTISGAKNAALPILFASLLSKGNVNLTNVPLLKDISTTLELLKEL
CCEEEECCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHH
GAEASQDGHEVHINASSVKNYTASYELVRSMRASILALGPLVARFGEADISLPGGCAIGA
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECC
RPVNLHIHGLEQMGAIIKVQNGFIKARVNGRLKGAHLYMDMVSVTGTGNLMMAAALAEGV
EEEEEEEECHHHCCCEEEEECCEEEEEECCEEEEEEEEEEEEEECCCCCHHHHHHHHHHH
TTIENAAKEPELVDLANFINGMGGKISGAGTDTLTIEGVESLGDCSYQVQPDRIETGTFL
HHHHHHCCCCCHHHHHHHHCCCCCEECCCCCCEEEEECCCCCCCCCEEECCCCCCCCCEE
VAGVVSGGKVKCLKTAPHLLTAVLSKLEEAGAAVTTGSDWIEVDMIDRQLKSVNISTAPH
EEEECCCCEEEEEECCHHHHHHHHHHHHHCCCEEECCCCEEEEEHHHHHHHHCCCCCCCC
PAFPTDMQAQFTVLNTVAPGTGRIKENIFENRFMHVPELQRMGANIILEGNLAICGDPDP
CCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCHHHHCCCCEEEECCEEEECCCCC
LCGAEVMATDLRASASLVIAGLIAEGETIVDEIYHIDRGYEAIENKLIALGAKIKRIEN
CCCHHHHHHHHHCCCCEEEEEEHHCCHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA