Click here to switch to the map view.

The map label for this gene is ubiB [H]

Identifier: 119946477

GI number: 119946477

Start: 3529983

End: 3531662

Strand: Reverse

Name: ubiB [H]

Synonym: Ping_2852

Alternate gene names: 119946477

Gene position: 3531662-3529983 (Counterclockwise)

Preceding gene: 119946478

Following gene: 119946476

Centisome position: 77.46

GC content: 46.49

Gene sequence:

>1680_bases
ATGCTTTGGGAAACACTAGGTGCTGCCCGTGATATCAGGAGAATTAATGATATTGCCACTATATTGATCCGTTATGGTTT
TGGAAATATGGTGCACAGATTAGGATTAGCGGGTGTAATAGAGCGTGCGGGTAAGGTGCTACATCGGACACAAGCTACTG
AATTAGCGCTACTTGAGCCTCCGGTAAGGTTCCGACATGCCTTGGAGGAGATGGGGCCTACTTTTATTAAACTTGGGCAG
ATTTTCTCCACGCGTGTCGATCTTTTTTCTCCCGAATGGATTATTGAATTTGAGAAGCTGCAGGATCAGGCTCAGGCTGT
TCCATTCGCGGCAATCTGTCAGCAATTGCAGGAAGATTTTGGATGTGCGCCACAAGAGGTATTCGCTGAATTTAATCCCG
AACCCTTAGCCGCTGCATCGATAGCGCAAGTACATCGAGCACGTTTGCATGACGGTAGTGCAGTTGTTATTAAAGTGCGT
CGTCCGGGGATTCGGCCAATAATGGAAGCGGATCTGCGTCTGCTTGCACGTATAGCCGATCTTATTGAATCCGAATCCAC
AACGTTGAGCCGCTTCAAGCCCCGTGAGGTGGTGCATCAGTTTACACTTTCTCTGCGACGGGAACTGGATTTGCTGGCTG
AATGTCGTAATGCGGAAAGGATTGCGCTCAATTTTAGTGACCATCCTGAGATTATTGTTCCGAAAGTTTACTGGCCGTGG
TGTAGTGAACGGGTGAATGTCCAGGAATATATTGAGGGTATTCCAGGTCGCAATCTTGATGCCATAGATAAAGCTAATCT
TAACCGAAAAATTTTGGCTCAGCATGGCGGTGAAGCTGCCTTGAAAATGATCCTGATAGATGGTTTTTTTCATGCAGATC
CTCATCAGGGTAATATTTTTTATCTGCCGGGAAACCGCATTGCTTTTATTGACTTTGGTATGGTCGGACGCCTCTCTGAG
CGTCGCCGAAATCAAGTTGTGAATCTTTTGTATAGTATGGTGGAGCAGGACAGTGCAAGTGTCGTTGAAGTGCTGCTCGA
TTGGGCTGGAGATTCATCCATAGATACCGAAGGTCTGCTTCTTGAGGTTGAAGGTTTTATCGATCAATATTACAAGGTTT
CATTAAAAGATTTTAACCTTGGTTCGATGCTGATCGAGTTGACCACATTATTTCGTGAGCATGGTTTAAATTTACCGCCT
GATCTGGTTCTTTTGATTAAGCCACTTATCACTCTTGAGGGGGTCGCCAGACAACTGGATCCTGATTATAATATGGTGAT
ACAAGCATCTCCCTTTTTAGAGCATGTTATGCGCGAGCGTTATGCACCCAATGTTTTGGCGAAGAGAAGCTGGCAAGCTG
TGGTGGGTACCGTTGAGCTATTATCTGGACTGCCTCAGGATCTTCGCCAGTTTTTGCGCTCCGCCCGTAGTGGCCGGTTT
CAGTTACATGTCGATGTGACGCGGTTGAAGACATTTGGTAATCAACTCGATCGTGCTGCCAGCCGCATGGCGTTGGGAAA
TGTTGTCGCGTCATTAATTATCGGTTCTTCTATTGTGATGACAGTTGACGGGGGACCGACCCTATTTGGTTTTCCCTTGT
TTGGAATGCTCGGATTTATCGCAGCATTCCTTGGCGGGATTTGGCTGTTGGTCTCAATCTGGTCCAGTGGACAAGAATGA

Upstream 100 bases:

>100_bases
AGCTCTCTTATGCGGCGGCAGGTTTTCTTGACGGCATTGCACAAACATTGGAAAGCAAATTAAAAACGACTTCTTTGAAA
AACAAAAAATAGGAAGCGCT

Downstream 100 bases:

>100_bases
GTCTCTGTTTGTGATCTGCAGTATGTAAAAAGAGAGGGGGATTGCTAATTGAGGACGCTTTTAGATGAATTCGAAGGGTA
GTATTTGTGCGCACGATCGA

Product: ubiquinone biosynthesis protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MLWETLGAARDIRRINDIATILIRYGFGNMVHRLGLAGVIERAGKVLHRTQATELALLEPPVRFRHALEEMGPTFIKLGQ
IFSTRVDLFSPEWIIEFEKLQDQAQAVPFAAICQQLQEDFGCAPQEVFAEFNPEPLAAASIAQVHRARLHDGSAVVIKVR
RPGIRPIMEADLRLLARIADLIESESTTLSRFKPREVVHQFTLSLRRELDLLAECRNAERIALNFSDHPEIIVPKVYWPW
CSERVNVQEYIEGIPGRNLDAIDKANLNRKILAQHGGEAALKMILIDGFFHADPHQGNIFYLPGNRIAFIDFGMVGRLSE
RRRNQVVNLLYSMVEQDSASVVEVLLDWAGDSSIDTEGLLLEVEGFIDQYYKVSLKDFNLGSMLIELTTLFREHGLNLPP
DLVLLIKPLITLEGVARQLDPDYNMVIQASPFLEHVMRERYAPNVLAKRSWQAVVGTVELLSGLPQDLRQFLRSARSGRF
QLHVDVTRLKTFGNQLDRAASRMALGNVVASLIIGSSIVMTVDGGPTLFGFPLFGMLGFIAAFLGGIWLLVSIWSSGQE

Sequences:

>Translated_559_residues
MLWETLGAARDIRRINDIATILIRYGFGNMVHRLGLAGVIERAGKVLHRTQATELALLEPPVRFRHALEEMGPTFIKLGQ
IFSTRVDLFSPEWIIEFEKLQDQAQAVPFAAICQQLQEDFGCAPQEVFAEFNPEPLAAASIAQVHRARLHDGSAVVIKVR
RPGIRPIMEADLRLLARIADLIESESTTLSRFKPREVVHQFTLSLRRELDLLAECRNAERIALNFSDHPEIIVPKVYWPW
CSERVNVQEYIEGIPGRNLDAIDKANLNRKILAQHGGEAALKMILIDGFFHADPHQGNIFYLPGNRIAFIDFGMVGRLSE
RRRNQVVNLLYSMVEQDSASVVEVLLDWAGDSSIDTEGLLLEVEGFIDQYYKVSLKDFNLGSMLIELTTLFREHGLNLPP
DLVLLIKPLITLEGVARQLDPDYNMVIQASPFLEHVMRERYAPNVLAKRSWQAVVGTVELLSGLPQDLRQFLRSARSGRF
QLHVDVTRLKTFGNQLDRAASRMALGNVVASLIIGSSIVMTVDGGPTLFGFPLFGMLGFIAAFLGGIWLLVSIWSSGQE
>Mature_559_residues
MLWETLGAARDIRRINDIATILIRYGFGNMVHRLGLAGVIERAGKVLHRTQATELALLEPPVRFRHALEEMGPTFIKLGQ
IFSTRVDLFSPEWIIEFEKLQDQAQAVPFAAICQQLQEDFGCAPQEVFAEFNPEPLAAASIAQVHRARLHDGSAVVIKVR
RPGIRPIMEADLRLLARIADLIESESTTLSRFKPREVVHQFTLSLRRELDLLAECRNAERIALNFSDHPEIIVPKVYWPW
CSERVNVQEYIEGIPGRNLDAIDKANLNRKILAQHGGEAALKMILIDGFFHADPHQGNIFYLPGNRIAFIDFGMVGRLSE
RRRNQVVNLLYSMVEQDSASVVEVLLDWAGDSSIDTEGLLLEVEGFIDQYYKVSLKDFNLGSMLIELTTLFREHGLNLPP
DLVLLIKPLITLEGVARQLDPDYNMVIQASPFLEHVMRERYAPNVLAKRSWQAVVGTVELLSGLPQDLRQFLRSARSGRF
QLHVDVTRLKTFGNQLDRAASRMALGNVVASLIIGSSIVMTVDGGPTLFGFPLFGMLGFIAAFLGGIWLLVSIWSSGQE

Specific function: Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis [H]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC1 family. UbiB subfamily [H]

Homologues:

Organism=Homo sapiens, GI41393593, Length=270, Percent_Identity=32.2222222222222, Blast_Score=139, Evalue=9e-33,
Organism=Homo sapiens, GI40254938, Length=275, Percent_Identity=30.9090909090909, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI217035081, Length=224, Percent_Identity=30.8035714285714, Blast_Score=116, Evalue=6e-26,
Organism=Homo sapiens, GI32261307, Length=333, Percent_Identity=26.4264264264264, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI34147522, Length=276, Percent_Identity=26.0869565217391, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI27363457, Length=278, Percent_Identity=24.8201438848921, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI217416386, Length=283, Percent_Identity=24.0282685512367, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI2367309, Length=553, Percent_Identity=32.5497287522604, Blast_Score=239, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI17559152, Length=281, Percent_Identity=27.0462633451957, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI32565180, Length=345, Percent_Identity=26.0869565217391, Blast_Score=98, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6325148, Length=435, Percent_Identity=26.2068965517241, Blast_Score=137, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6323282, Length=242, Percent_Identity=28.099173553719, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6321319, Length=255, Percent_Identity=24.3137254901961, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI22024280, Length=271, Percent_Identity=32.4723247232472, Blast_Score=150, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24662575, Length=257, Percent_Identity=31.5175097276265, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI18859849, Length=248, Percent_Identity=29.0322580645161, Blast_Score=83, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719
- InterPro:   IPR010232 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 62736; Mature: 62736

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWETLGAARDIRRINDIATILIRYGFGNMVHRLGLAGVIERAGKVLHRTQATELALLEP
CCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
PVRFRHALEEMGPTFIKLGQIFSTRVDLFSPEWIIEFEKLQDQAQAVPFAAICQQLQEDF
CHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHEEHHHHHHHHHCCCHHHHHHHHHHHH
GCAPQEVFAEFNPEPLAAASIAQVHRARLHDGSAVVIKVRRPGIRPIMEADLRLLARIAD
CCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
LIESESTTLSRFKPREVVHQFTLSLRRELDLLAECRNAERIALNFSDHPEIIVPKVYWPW
HHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEECCEECCC
CSERVNVQEYIEGIPGRNLDAIDKANLNRKILAQHGGEAALKMILIDGFFHADPHQGNIF
CCCCCCHHHHHCCCCCCCCCCHHHCCCCHHHHHHCCCHHHHHHHHEECEECCCCCCCCEE
YLPGNRIAFIDFGMVGRLSERRRNQVVNLLYSMVEQDSASVVEVLLDWAGDSSIDTEGLL
EECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEE
LEVEGFIDQYYKVSLKDFNLGSMLIELTTLFREHGLNLPPDLVLLIKPLITLEGVARQLD
EEEHHHHHHHHEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
PDYNMVIQASPFLEHVMRERYAPNVLAKRSWQAVVGTVELLSGLPQDLRQFLRSARSGRF
CCCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCE
QLHVDVTRLKTFGNQLDRAASRMALGNVVASLIIGSSIVMTVDGGPTLFGFPLFGMLGFI
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEHHHHHHHHHHH
AAFLGGIWLLVSIWSSGQE
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLWETLGAARDIRRINDIATILIRYGFGNMVHRLGLAGVIERAGKVLHRTQATELALLEP
CCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCC
PVRFRHALEEMGPTFIKLGQIFSTRVDLFSPEWIIEFEKLQDQAQAVPFAAICQQLQEDF
CHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHEEHHHHHHHHHCCCHHHHHHHHHHHH
GCAPQEVFAEFNPEPLAAASIAQVHRARLHDGSAVVIKVRRPGIRPIMEADLRLLARIAD
CCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
LIESESTTLSRFKPREVVHQFTLSLRRELDLLAECRNAERIALNFSDHPEIIVPKVYWPW
HHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEECCEECCC
CSERVNVQEYIEGIPGRNLDAIDKANLNRKILAQHGGEAALKMILIDGFFHADPHQGNIF
CCCCCCHHHHHCCCCCCCCCCHHHCCCCHHHHHHCCCHHHHHHHHEECEECCCCCCCCEE
YLPGNRIAFIDFGMVGRLSERRRNQVVNLLYSMVEQDSASVVEVLLDWAGDSSIDTEGLL
EECCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEE
LEVEGFIDQYYKVSLKDFNLGSMLIELTTLFREHGLNLPPDLVLLIKPLITLEGVARQLD
EEEHHHHHHHHEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
PDYNMVIQASPFLEHVMRERYAPNVLAKRSWQAVVGTVELLSGLPQDLRQFLRSARSGRF
CCCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCE
QLHVDVTRLKTFGNQLDRAASRMALGNVVASLIIGSSIVMTVDGGPTLFGFPLFGMLGFI
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCEEHHHHHHHHHHH
AAFLGGIWLLVSIWSSGQE
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]