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The map label for this gene is ompR [H]

Identifier: 119946428

GI number: 119946428

Start: 3447708

End: 3448448

Strand: Reverse

Name: ompR [H]

Synonym: Ping_2802

Alternate gene names: 119946428

Gene position: 3448448-3447708 (Counterclockwise)

Preceding gene: 119946429

Following gene: 119946426

Centisome position: 75.63

GC content: 40.89

Gene sequence:

>741_bases
ATGGATGATCGTTCTAAAAAACCGATTCTGATAGTTGATGATGAAGTTGACGTGCGCATTCTGGTAAGCGATGTTTTAAA
TCAAGCAGGCTATCCCTGTGTTGCCGTTGCAGACGGAAATACCATGTTTGGCGAAATGAAAAAGGCGCTCTTTAGTTTAT
TAATCATTGATCTGCGGTTGAAAAATGAAGATGGTTTAGTACTTGCGCGTAGCGTAAGAGAAAACAGCAATATACCTATT
TTAATGTTGACTGGAAAAGGTTCTGAAACGGATAGAATTTTAAGTTTGGAAATTGCTGCCGATGATTTTCTGATGAAACC
TTTTAATATTAGAGAACTGGTTGCCAGAGTTAACGCATTGCAGCGCAGAGCCGTGATGACTATAAACAATGATCCTGCCG
ACTTATCTGATTCACATGAGTGTTTATCTTTTGGTCACTGGATTCTTGATTTATCCGCCCGTGAATTACGCAACAGCAGC
GGAGAAGTTACCCTGCTAACCTATGGCGAATTTACGCTGTTAGAAAGTCTGGCTACAAGACCTAAACGGGTCATATCCCG
AGAGCAGTTATTAGAATATCTTCGTGGTGCGGAGGGGGATACCTTTGACCGTACTGTTGATGTGTTAATATCTCGCTTAC
GCCAGAAGTTGGAAATCAATTCAAGAAGTCCCAGATACATACGCACAGAACGGGGCATAGGGTATAGTTTTTCTGAAAAT
GTAAGTAAAAGCATAAGATGA

Upstream 100 bases:

>100_bases
GTTGTAGTTTATAATTATGGAACATTTTTATTGTTATTTATTATGAAAAACGGCTAAATACAGAGAATAATATTTCCTAA
AATCAAGGTGTAAATTGTAG

Downstream 100 bases:

>100_bases
TTATCCTTTTTTATTGACCTCGTTTAATGTGAAGTCGATAAAACGCCTGTTGGCTATTGATAAATAACCGTCTTTTCGCC
ACGCAAATGCAAGGTCGAGA

Product: two component transcriptional regulator, winged helix family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MDDRSKKPILIVDDEVDVRILVSDVLNQAGYPCVAVADGNTMFGEMKKALFSLLIIDLRLKNEDGLVLARSVRENSNIPI
LMLTGKGSETDRILSLEIAADDFLMKPFNIRELVARVNALQRRAVMTINNDPADLSDSHECLSFGHWILDLSARELRNSS
GEVTLLTYGEFTLLESLATRPKRVISREQLLEYLRGAEGDTFDRTVDVLISRLRQKLEINSRSPRYIRTERGIGYSFSEN
VSKSIR

Sequences:

>Translated_246_residues
MDDRSKKPILIVDDEVDVRILVSDVLNQAGYPCVAVADGNTMFGEMKKALFSLLIIDLRLKNEDGLVLARSVRENSNIPI
LMLTGKGSETDRILSLEIAADDFLMKPFNIRELVARVNALQRRAVMTINNDPADLSDSHECLSFGHWILDLSARELRNSS
GEVTLLTYGEFTLLESLATRPKRVISREQLLEYLRGAEGDTFDRTVDVLISRLRQKLEINSRSPRYIRTERGIGYSFSEN
VSKSIR
>Mature_246_residues
MDDRSKKPILIVDDEVDVRILVSDVLNQAGYPCVAVADGNTMFGEMKKALFSLLIIDLRLKNEDGLVLARSVRENSNIPI
LMLTGKGSETDRILSLEIAADDFLMKPFNIRELVARVNALQRRAVMTINNDPADLSDSHECLSFGHWILDLSARELRNSS
GEVTLLTYGEFTLLESLATRPKRVISREQLLEYLRGAEGDTFDRTVDVLISRLRQKLEINSRSPRYIRTERGIGYSFSEN
VSKSIR

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=237, Percent_Identity=40.9282700421941, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=37.3913043478261, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1786599, Length=234, Percent_Identity=36.7521367521368, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1788394, Length=243, Percent_Identity=35.3909465020576, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1787229, Length=235, Percent_Identity=34.8936170212766, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=35.2173913043478, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1790860, Length=234, Percent_Identity=32.9059829059829, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=33.1877729257642, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787375, Length=231, Percent_Identity=34.1991341991342, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=32.0175438596491, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87082012, Length=235, Percent_Identity=32.3404255319149, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=31.063829787234, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790552, Length=235, Percent_Identity=33.1914893617021, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1789402, Length=233, Percent_Identity=30.4721030042918, Blast_Score=91, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27789; Mature: 27789

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDRSKKPILIVDDEVDVRILVSDVLNQAGYPCVAVADGNTMFGEMKKALFSLLIIDLRL
CCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHEEE
KNEDGLVLARSVRENSNIPILMLTGKGSETDRILSLEIAADDFLMKPFNIRELVARVNAL
CCCCCEEEEEECCCCCCCCEEEEECCCCCCCEEEEEEEECCCCEECCCCHHHHHHHHHHH
QRRAVMTINNDPADLSDSHECLSFGHWILDLSARELRNSSGEVTLLTYGEFTLLESLATR
HHHEEEEECCCCCCCCCCHHHHHHHHHHEECCHHHHCCCCCCEEEEECCHHHHHHHHHCC
PKRVISREQLLEYLRGAEGDTFDRTVDVLISRLRQKLEINSRSPRYIRTERGIGYSFSEN
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHH
VSKSIR
HHHHCC
>Mature Secondary Structure
MDDRSKKPILIVDDEVDVRILVSDVLNQAGYPCVAVADGNTMFGEMKKALFSLLIIDLRL
CCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHEEE
KNEDGLVLARSVRENSNIPILMLTGKGSETDRILSLEIAADDFLMKPFNIRELVARVNAL
CCCCCEEEEEECCCCCCCCEEEEECCCCCCCEEEEEEEECCCCEECCCCHHHHHHHHHHH
QRRAVMTINNDPADLSDSHECLSFGHWILDLSARELRNSSGEVTLLTYGEFTLLESLATR
HHHEEEEECCCCCCCCCCHHHHHHHHHHEECCHHHHCCCCCCEEEEECCHHHHHHHHHCC
PKRVISREQLLEYLRGAEGDTFDRTVDVLISRLRQKLEINSRSPRYIRTERGIGYSFSEN
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHH
VSKSIR
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]