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The map label for this gene is hflK [H]

Identifier: 119946424

GI number: 119946424

Start: 3443532

End: 3444605

Strand: Reverse

Name: hflK [H]

Synonym: Ping_2798

Alternate gene names: 119946424

Gene position: 3444605-3443532 (Counterclockwise)

Preceding gene: 119946425

Following gene: 119946423

Centisome position: 75.55

GC content: 44.04

Gene sequence:

>1074_bases
ATGTCGACAGAAAATGAGCAGGACCCCCGAACTCCTTGGGATAATAATCAAGGTTTTCCTCCGGAATATGGTTTATTAAT
GAAGAGAGGATATTCGCACTATAAAAGAAGGCTTCTGGGTAGACACTCAAGGGGAGCTGGCCGGTATGTTTTTTATATTT
TGTTTTTATTGCTGGCTGGAATAAGCCTCTGGTCCGCTATTTACACTATTCCCAGTGATTCTGTTGCGGTTGTACAGCGA
TTTGGAAAATATTTAAAAGAAGTGCCTGCCGGACTGCATATTAAAATGCCACTTGGTATTGACCGTGCCACTATTGTTCC
GGTTAAAAGACAATTAAAGCAAGAGTTTGGTTTTACCACACCGGATGCGACGGATCCTTATCAAAGTTCCGGTGTGAGAG
CGAGCGAACAGGAAACACAAATGGTCACCGGTGATTTAAATGCCGCCCTTGTGGAGTGGGTAGTTCAGTATCGTATTGCC
GATCCGGTTAAATTCTTATTTAAAGTGCGCCAGCCCAGTGAAACCCTGCGCTCAGTTTCAGAATCAGTGATGCGTGAAGT
GGTGGGGGATCGTACCGTTGATGAAGTGATCACTATTGGCCGTCAGGAGATTGAGTATGAAGCATTGACCAAAATGCAGG
CGCTTTCCAGTAAATATGAAATGGGGATCAGTATTGATCAGGTACAGCTAAAAAATATTAACCCGCCAAAGCCAGTTCAG
GCATCTTTTAACGAAGTAAACCAAGCGCAGCAGGAAAAAGAAAAGCTAATTAATGAAGCTCGGCGTGACTACAATAAAGT
TATTCCATTAGCGCTGGGTGAAAAAGATCAACGTATTCGTGAGGCTGATGGTTACCGGCTTAAACGCATTAACGAGGCTG
AAGGTGATGTTGCGCGATTTAATGCACTGTTCGCTGAATACCTTAAGGCGCCTGAAGTCACAAAGAGACGTATCTATCTT
GAGACAATGCAGGCGGTGTTACCACAGATACGCTCCAAAATAATTATCGATTCAAACAGCCCGAGTATTTTGCCATGGTT
AGATCTTAATGCGGCCCAGGGAGAAAAGCCATGA

Upstream 100 bases:

>100_bases
TTGATCAATAGAGTACTTTTAATCCTCACTTCTTGACAATCTTAGTGATCATTCCATAGTCAATATAGGGCATACTTTTG
TGCCGTTAATAGGGGTTATT

Downstream 100 bases:

>100_bases
AGAACATAACAACAGGATTTGCATTATTATTGATAGCACTGGTGGTTATGACATTAAAATCGACGCTTTACACTGTGGGT
GAAGTTGAGCAGGTTATTAT

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSTENEQDPRTPWDNNQGFPPEYGLLMKRGYSHYKRRLLGRHSRGAGRYVFYILFLLLAGISLWSAIYTIPSDSVAVVQR
FGKYLKEVPAGLHIKMPLGIDRATIVPVKRQLKQEFGFTTPDATDPYQSSGVRASEQETQMVTGDLNAALVEWVVQYRIA
DPVKFLFKVRQPSETLRSVSESVMREVVGDRTVDEVITIGRQEIEYEALTKMQALSSKYEMGISIDQVQLKNINPPKPVQ
ASFNEVNQAQQEKEKLINEARRDYNKVIPLALGEKDQRIREADGYRLKRINEAEGDVARFNALFAEYLKAPEVTKRRIYL
ETMQAVLPQIRSKIIIDSNSPSILPWLDLNAAQGEKP

Sequences:

>Translated_357_residues
MSTENEQDPRTPWDNNQGFPPEYGLLMKRGYSHYKRRLLGRHSRGAGRYVFYILFLLLAGISLWSAIYTIPSDSVAVVQR
FGKYLKEVPAGLHIKMPLGIDRATIVPVKRQLKQEFGFTTPDATDPYQSSGVRASEQETQMVTGDLNAALVEWVVQYRIA
DPVKFLFKVRQPSETLRSVSESVMREVVGDRTVDEVITIGRQEIEYEALTKMQALSSKYEMGISIDQVQLKNINPPKPVQ
ASFNEVNQAQQEKEKLINEARRDYNKVIPLALGEKDQRIREADGYRLKRINEAEGDVARFNALFAEYLKAPEVTKRRIYL
ETMQAVLPQIRSKIIIDSNSPSILPWLDLNAAQGEKP
>Mature_356_residues
STENEQDPRTPWDNNQGFPPEYGLLMKRGYSHYKRRLLGRHSRGAGRYVFYILFLLLAGISLWSAIYTIPSDSVAVVQRF
GKYLKEVPAGLHIKMPLGIDRATIVPVKRQLKQEFGFTTPDATDPYQSSGVRASEQETQMVTGDLNAALVEWVVQYRIAD
PVKFLFKVRQPSETLRSVSESVMREVVGDRTVDEVITIGRQEIEYEALTKMQALSSKYEMGISIDQVQLKNINPPKPVQA
SFNEVNQAQQEKEKLINEARRDYNKVIPLALGEKDQRIREADGYRLKRINEAEGDVARFNALFAEYLKAPEVTKRRIYLE
TMQAVLPQIRSKIIIDSNSPSILPWLDLNAAQGEKP

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=293, Percent_Identity=34.1296928327645, Blast_Score=155, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 40677; Mature: 40546

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTENEQDPRTPWDNNQGFPPEYGLLMKRGYSHYKRRLLGRHSRGAGRYVFYILFLLLAG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
ISLWSAIYTIPSDSVAVVQRFGKYLKEVPAGLHIKMPLGIDRATIVPVKRQLKQEFGFTT
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCC
PDATDPYQSSGVRASEQETQMVTGDLNAALVEWVVQYRIADPVKFLFKVRQPSETLRSVS
CCCCCCCHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ESVMREVVGDRTVDEVITIGRQEIEYEALTKMQALSSKYEMGISIDQVQLKNINPPKPVQ
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCH
ASFNEVNQAQQEKEKLINEARRDYNKVIPLALGEKDQRIREADGYRLKRINEAEGDVARF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHCCCCCCCHHHHH
NALFAEYLKAPEVTKRRIYLETMQAVLPQIRSKIIIDSNSPSILPWLDLNAAQGEKP
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure 
STENEQDPRTPWDNNQGFPPEYGLLMKRGYSHYKRRLLGRHSRGAGRYVFYILFLLLAG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
ISLWSAIYTIPSDSVAVVQRFGKYLKEVPAGLHIKMPLGIDRATIVPVKRQLKQEFGFTT
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCC
PDATDPYQSSGVRASEQETQMVTGDLNAALVEWVVQYRIADPVKFLFKVRQPSETLRSVS
CCCCCCCHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ESVMREVVGDRTVDEVITIGRQEIEYEALTKMQALSSKYEMGISIDQVQLKNINPPKPVQ
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCH
ASFNEVNQAQQEKEKLINEARRDYNKVIPLALGEKDQRIREADGYRLKRINEAEGDVARF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHCCCCCCCHHHHH
NALFAEYLKAPEVTKRRIYLETMQAVLPQIRSKIIIDSNSPSILPWLDLNAAQGEKP
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]