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The map label for this gene is hflC [H]

Identifier: 119946423

GI number: 119946423

Start: 3442537

End: 3443535

Strand: Reverse

Name: hflC [H]

Synonym: Ping_2797

Alternate gene names: 119946423

Gene position: 3443535-3442537 (Counterclockwise)

Preceding gene: 119946424

Following gene: 119946421

Centisome position: 75.52

GC content: 45.45

Gene sequence:

>999_bases
ATGAAGAACATAACAACAGGATTTGCATTATTATTGATAGCACTGGTGGTTATGACATTAAAATCGACGCTTTACACTGT
GGGTGAAGTTGAGCAGGTTATTATTACACAGTTTGGAAAGCCGGTAGGTACCCCTGTTACCAATGCGGGTTTGAAGGCAA
AATTCCCCTTTATACAAGAGGTCAACAGCATAGATAAAAGAGTCTTAGAGTGGGATGGCGAACCATCGGATATGCCGACT
AAAGATAAGCTCTATATCTCTGTGGATCTTTTTGCCCGCTGGCGGATAACCGATCCTCTGCAATATTTTCTGCGCTTGCG
CGATGAGCGCAGCGCCCAATCAAGACTGGACGATATTCTTGGCAGTGAAACCCGTAATGCTGTGGCAAAACACGAATTAA
TCGAGATAATCCGCACCACAAAAGATCGGGAGCCGCTGCGTGATGATCTTCTGACCGATGCCGAGCGCGCGCTGAAAATG
GGTTCTCTGGTGCCCATTCAGAAAGGCCGTATGCTGGTGGAGCAAGAAATTTTTATTGCTGCAGCCGAAAAAGTGCAGGT
GTTTGGTATTGAGCTTCTGGATATCCGCTTTAAACGCATTAATTACAATGCGAGTGTGCGGCCCAAAATTTATGATCGTA
TGATCAGTGAGCGCAGGCAGATTGCCGAGCGTTTTCTGTCCGAGGGAAATGGTGAAGCCGCCAGAATTCGAGGGAATCGT
CTTCGGGATTTAAATAAAATACAGTCAGAAGCCTATCGGCAGGTAGAGGAGATTCAGGGCGTTGCTGATGCCAAAGCCTC
TGAAATTTATGCGCGGGCATACAATCAAAGCCCTCAATCTGTTGGTTTGTATGAGTTTACCCGCACGATGCAGGCATACC
GGAGTATTATTGCGCAGAATACAACTTTGGTCTTATCGACAGACAGTGACCTGTTTAAATTTCTTAAGGGAATTAATGTG
GATAAAATGCCATTGCCAAAAGAGGGGAATATTCCTTAA

Upstream 100 bases:

>100_bases
AGGCGGTGTTACCACAGATACGCTCCAAAATAATTATCGATTCAAACAGCCCGAGTATTTTGCCATGGTTAGATCTTAAT
GCGGCCCAGGGAGAAAAGCC

Downstream 100 bases:

>100_bases
GCATTATTGCCTTCGAGCTTCCTGCCTTACAGCTGACGGCTTACAGCCGTCAGCCCTTTTTAATCACGAAAAACGATATC
AAAGTTACCTGAGCGTACCC

Product: HflC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKNITTGFALLLIALVVMTLKSTLYTVGEVEQVIITQFGKPVGTPVTNAGLKAKFPFIQEVNSIDKRVLEWDGEPSDMPT
KDKLYISVDLFARWRITDPLQYFLRLRDERSAQSRLDDILGSETRNAVAKHELIEIIRTTKDREPLRDDLLTDAERALKM
GSLVPIQKGRMLVEQEIFIAAAEKVQVFGIELLDIRFKRINYNASVRPKIYDRMISERRQIAERFLSEGNGEAARIRGNR
LRDLNKIQSEAYRQVEEIQGVADAKASEIYARAYNQSPQSVGLYEFTRTMQAYRSIIAQNTTLVLSTDSDLFKFLKGINV
DKMPLPKEGNIP

Sequences:

>Translated_332_residues
MKNITTGFALLLIALVVMTLKSTLYTVGEVEQVIITQFGKPVGTPVTNAGLKAKFPFIQEVNSIDKRVLEWDGEPSDMPT
KDKLYISVDLFARWRITDPLQYFLRLRDERSAQSRLDDILGSETRNAVAKHELIEIIRTTKDREPLRDDLLTDAERALKM
GSLVPIQKGRMLVEQEIFIAAAEKVQVFGIELLDIRFKRINYNASVRPKIYDRMISERRQIAERFLSEGNGEAARIRGNR
LRDLNKIQSEAYRQVEEIQGVADAKASEIYARAYNQSPQSVGLYEFTRTMQAYRSIIAQNTTLVLSTDSDLFKFLKGINV
DKMPLPKEGNIP
>Mature_332_residues
MKNITTGFALLLIALVVMTLKSTLYTVGEVEQVIITQFGKPVGTPVTNAGLKAKFPFIQEVNSIDKRVLEWDGEPSDMPT
KDKLYISVDLFARWRITDPLQYFLRLRDERSAQSRLDDILGSETRNAVAKHELIEIIRTTKDREPLRDDLLTDAERALKM
GSLVPIQKGRMLVEQEIFIAAAEKVQVFGIELLDIRFKRINYNASVRPKIYDRMISERRQIAERFLSEGNGEAARIRGNR
LRDLNKIQSEAYRQVEEIQGVADAKASEIYARAYNQSPQSVGLYEFTRTMQAYRSIIAQNTTLVLSTDSDLFKFLKGINV
DKMPLPKEGNIP

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=312, Percent_Identity=29.1666666666667, Blast_Score=118, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 37846; Mature: 37846

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNITTGFALLLIALVVMTLKSTLYTVGEVEQVIITQFGKPVGTPVTNAGLKAKFPFIQE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
VNSIDKRVLEWDGEPSDMPTKDKLYISVDLFARWRITDPLQYFLRLRDERSAQSRLDDIL
HHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
GSETRNAVAKHELIEIIRTTKDREPLRDDLLTDAERALKMGSLVPIQKGRMLVEQEIFIA
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
AAEKVQVFGIELLDIRFKRINYNASVRPKIYDRMISERRQIAERFLSEGNGEAARIRGNR
HHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHH
LRDLNKIQSEAYRQVEEIQGVADAKASEIYARAYNQSPQSVGLYEFTRTMQAYRSIIAQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC
TTLVLSTDSDLFKFLKGINVDKMPLPKEGNIP
CEEEEECCHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKNITTGFALLLIALVVMTLKSTLYTVGEVEQVIITQFGKPVGTPVTNAGLKAKFPFIQE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
VNSIDKRVLEWDGEPSDMPTKDKLYISVDLFARWRITDPLQYFLRLRDERSAQSRLDDIL
HHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
GSETRNAVAKHELIEIIRTTKDREPLRDDLLTDAERALKMGSLVPIQKGRMLVEQEIFIA
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
AAEKVQVFGIELLDIRFKRINYNASVRPKIYDRMISERRQIAERFLSEGNGEAARIRGNR
HHHHHHHHCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHH
LRDLNKIQSEAYRQVEEIQGVADAKASEIYARAYNQSPQSVGLYEFTRTMQAYRSIIAQN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC
TTLVLSTDSDLFKFLKGINVDKMPLPKEGNIP
CEEEEECCHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]