| Definition | Psychromonas ingrahamii 37, complete genome. |
|---|---|
| Accession | NC_008709 |
| Length | 4,559,598 |
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The map label for this gene is cysG [H]
Identifier: 119946381
GI number: 119946381
Start: 3380283
End: 3381227
Strand: Direct
Name: cysG [H]
Synonym: Ping_2755
Alternate gene names: 119946381
Gene position: 3380283-3381227 (Clockwise)
Preceding gene: 119946377
Following gene: 119946384
Centisome position: 74.14
GC content: 40.63
Gene sequence:
>945_bases ATGATGGACTATTTCCCGATTTTTTTAGATGCTAAAAAGTTTAATGCCGTGGTTATTGGAGGCGGTAATGTTGCTGCGCG AAAGATTGAACTTTTGCTCAAGTCAAAAGTGCAGATTACCGTTGTCAGCCCGGCACTTAAAGAGAGTGTAAAAGGACTGT TAGCAAACCAGCAACTCACTTGGATTGAAGCTGAATATGCGCCTCATTTTCTGGACAACCATCAGTTAGTGATAGCAGCA ACAAATATCAGATCGGTCAACATTACAATCAGTATTGCGGCGAATCATCGCGGTATGCTGCTCAATGTGGTTGACGATCC TGATCTTTGCAATTACATCACACCCGCAATTATTGACAGGGATCCGATGATTATTGCTATGTCAAGCTCAGGTAATGCCC CTATATTATTACAAATGTTAAAATCTCAAATAGAACAGATGTTACCCGCAGGTTATGGCAGATTAGCGCGCTTTTGTGGC CGCTACCGTATTGAAGTACAGGCCAGAATCAAACAGTTTTCCGAACGTAAACTGTTCTGGAAAAAAATATTGACGGGTGA TGTCGCCAAACAGTTACTGGCGGGTGATGAAGAACAAGCTGTACAGCTGTTTAATCAGGCGCTGACCACTGACAAATTTA AAGAAAGCGGCAGTATAAGTGTTATCAGAATTTATGATCAGCAACCTGATAATTTAACCCTGCAGGCGTATCAAAAAATG CAGCAGGCCGATGCAATATTTTTAGACTCTGATATTACAGCGTTATTTTTTGATTATGGGCGGCGCGATGCAGCTAAATT CCAAAAAATTGATAAACATAGTATTGAAAAATTGGCCGATAATAACCAACAAGTTGTTATTATCGCGGCACATTCTGCTC AATTAGTGTCAGCGTTTAATACTGACTCTCCCGTCTCAGAAATTATTTGCGGACGTGTTATTTAA
Upstream 100 bases:
>100_bases CTCTTATTTTGAAGAATAAACAATAAGTTAAAAAATAATTTATCGGGGTGATACTTAACCGTATCTGCTTTAATCAATAT ATTTGTTAACTAAGGCCAAG
Downstream 100 bases:
>100_bases CAATCAGCAGTTAAAAACTGGCATCGATCATAATATCAGCCTTTCTGACGGTTAACATTTTTGCGGTTCGAAAACTAAAA AGGGACAGCGCGCCCTTTTT
Product: siroheme synthase
Products: NA
Alternate protein names: Uroporphyrinogen-III C-methyltransferase; Urogen III methylase; SUMT; Uroporphyrinogen III methylase; UROM; Precorrin-2 dehydrogenase; Sirohydrochlorin ferrochelatase [H]
Number of amino acids: Translated: 314; Mature: 314
Protein sequence:
>314_residues MMDYFPIFLDAKKFNAVVIGGGNVAARKIELLLKSKVQITVVSPALKESVKGLLANQQLTWIEAEYAPHFLDNHQLVIAA TNIRSVNITISIAANHRGMLLNVVDDPDLCNYITPAIIDRDPMIIAMSSSGNAPILLQMLKSQIEQMLPAGYGRLARFCG RYRIEVQARIKQFSERKLFWKKILTGDVAKQLLAGDEEQAVQLFNQALTTDKFKESGSISVIRIYDQQPDNLTLQAYQKM QQADAIFLDSDITALFFDYGRRDAAKFQKIDKHSIEKLADNNQQVVIIAAHSAQLVSAFNTDSPVSEIICGRVI
Sequences:
>Translated_314_residues MMDYFPIFLDAKKFNAVVIGGGNVAARKIELLLKSKVQITVVSPALKESVKGLLANQQLTWIEAEYAPHFLDNHQLVIAA TNIRSVNITISIAANHRGMLLNVVDDPDLCNYITPAIIDRDPMIIAMSSSGNAPILLQMLKSQIEQMLPAGYGRLARFCG RYRIEVQARIKQFSERKLFWKKILTGDVAKQLLAGDEEQAVQLFNQALTTDKFKESGSISVIRIYDQQPDNLTLQAYQKM QQADAIFLDSDITALFFDYGRRDAAKFQKIDKHSIEKLADNNQQVVIIAAHSAQLVSAFNTDSPVSEIICGRVI >Mature_314_residues MMDYFPIFLDAKKFNAVVIGGGNVAARKIELLLKSKVQITVVSPALKESVKGLLANQQLTWIEAEYAPHFLDNHQLVIAA TNIRSVNITISIAANHRGMLLNVVDDPDLCNYITPAIIDRDPMIIAMSSSGNAPILLQMLKSQIEQMLPAGYGRLARFCG RYRIEVQARIKQFSERKLFWKKILTGDVAKQLLAGDEEQAVQLFNQALTTDKFKESGSISVIRIYDQQPDNLTLQAYQKM QQADAIFLDSDITALFFDYGRRDAAKFQKIDKHSIEKLADNNQQVVIIAAHSAQLVSAFNTDSPVSEIICGRVI
Specific function: Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into si
COG id: COG1648
COG function: function code H; Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the precorrin methyltransferase family [H]
Homologues:
Organism=Escherichia coli, GI1789768, Length=265, Percent_Identity=32.0754716981132, Blast_Score=162, Evalue=2e-41,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000878 - InterPro: IPR014777 - InterPro: IPR014776 - InterPro: IPR006366 - InterPro: IPR016040 - InterPro: IPR019478 - InterPro: IPR006367 - InterPro: IPR003043 [H]
Pfam domain/function: PF10414 CysG_dimeriser; PF00590 TP_methylase [H]
EC number: =2.1.1.107; =1.3.1.76; =4.99.1.4 [H]
Molecular weight: Translated: 35057; Mature: 35057
Theoretical pI: Translated: 8.06; Mature: 8.06
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.0 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 1.0 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 3.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MMDYFPIFLDAKKFNAVVIGGGNVAARKIELLLKSKVQITVVSPALKESVKGLLANQQLT CCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHCCCEEE WIEAEYAPHFLDNHQLVIAATNIRSVNITISIAANHRGMLLNVVDDPDLCNYITPAIIDR EEEECCCCCCCCCCEEEEEEECEEEEEEEEEEEECCCCEEEEEECCCCHHHHCCHHHCCC DPMIIAMSSSGNAPILLQMLKSQIEQMLPAGYGRLARFCGRYRIEVQARIKQFSERKLFW CCEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEEHHHHHHHHHHHHHH KKILTGDVAKQLLAGDEEQAVQLFNQALTTDKFKESGSISVIRIYDQQPDNLTLQAYQKM HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHH QQADAIFLDSDITALFFDYGRRDAAKFQKIDKHSIEKLADNNQQVVIIAAHSAQLVSAFN HHCCEEEECCCCCEEHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHCC TDSPVSEIICGRVI CCCCHHHHHCCCCC >Mature Secondary Structure MMDYFPIFLDAKKFNAVVIGGGNVAARKIELLLKSKVQITVVSPALKESVKGLLANQQLT CCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCEEEEEECHHHHHHHHHHHCCCEEE WIEAEYAPHFLDNHQLVIAATNIRSVNITISIAANHRGMLLNVVDDPDLCNYITPAIIDR EEEECCCCCCCCCCEEEEEEECEEEEEEEEEEEECCCCEEEEEECCCCHHHHCCHHHCCC DPMIIAMSSSGNAPILLQMLKSQIEQMLPAGYGRLARFCGRYRIEVQARIKQFSERKLFW CCEEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEEHHHHHHHHHHHHHH KKILTGDVAKQLLAGDEEQAVQLFNQALTTDKFKESGSISVIRIYDQQPDNLTLQAYQKM HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHH QQADAIFLDSDITALFFDYGRRDAAKFQKIDKHSIEKLADNNQQVVIIAAHSAQLVSAFN HHCCEEEECCCCCEEHHHHCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHCC TDSPVSEIICGRVI CCCCHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 12700255 [H]