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The map label for this gene is zwf [H]

Identifier: 119946380

GI number: 119946380

Start: 3378214

End: 3379713

Strand: Reverse

Name: zwf [H]

Synonym: Ping_2754

Alternate gene names: 119946380

Gene position: 3379713-3378214 (Counterclockwise)

Preceding gene: 119946382

Following gene: 119946379

Centisome position: 74.12

GC content: 42.07

Gene sequence:

>1500_bases
ATGTCAGTCATCGATACCAGCTGTATTGTCATATTTGGCGCTTCAGGCGATCTTACGCAGCGTATGCTTATTCCTGCGCT
TTATCATCTTTATGTCGATCAGAAGCTGCCAAAATCCTTCGCTATTCTGGGGGTAAGTCGCAGTATTTACAGTGATCAGG
CATTTCGTAGTAAATTAATAAAAAACATTAAATCTGATAAAAAAATTAATGAAGAATTATTAAATAAATTTTGTGAACAT
CTGTTTTATCAGGCGATTAATACCAGTGATGTGAATGATTACACACTGCTGAAAAAACGCATTTCCCGTATTAATGCTGA
TCGAGAGCTTAAAAATAACACCCTTTTTTACCTTGCCACGCCGCCCAGTTTATATTCTGTTATTCCCGAGCATCTAGCCG
CTGTCGGTCTTAATGAAGAGACGGATGGCTGGAAACGGCTAGTGGTTGAAAAACCCTTTGGTTCTGATCTTAAATCTGCA
GTGAGTCTCGATGAATCTCTGTATCGGCATTTTCAGGAACAGCAAATTTATCGTATTGATCATTACCTCGGTAAAGAAAC
GGTACAGAATATGCTGGTATTACGTTTTGCTAACAGCATTTTTGAGCCATTATGGAATGGCCGGTATATTGATTATGTAG
AAGTCACCGGGGCTGAAGCATTGGGTGTAGAACAGCGTGGTGGTTATTATGATGGTTCTGGTGCCATGCGGGATATGCTG
CAAAACCATTTATTACAGGTGATTGCAATGGTTGCAATGGAGCCCCCAGCCGTTATTAATGCCAAGTCAATGCGCGATGA
GGTGGTCAAAGTTTTACAATGTTTAAAACCACTTTCTCAAGATGACCTGGAAAATAATCTGGTGTTAGGGCAATATATTC
AGTCGCAGGTAAGAGGGAAATGTCTGCCGGCTTATCGCGAAGAAGAGGGTGTGCCGAATAACTCGAGAACAGAAACCTAT
GTCGGTCTTAAGCTGTTTATTAATAATTGGCGCTGGGATGGGGTACCATTTTATCTGCGTACCGGAAAGCGGCTGCCAAC
CCGGGTCACTGAAGTGGTTATCCATTTTAAAAAAACGCCTCATCCGGTTTTTTCAGCCGATGCCCCCGAAAACAAATTAA
TTATTCGCATTCAGCCCGATGAAGGGATCATGTTAGGTTTTGGCTTAAAGGAGCCTGGCGCGGGTTTTGATGCCAAAGAA
GTTGCCATGGACTTTCATTACAGTGACTTGAAAGAGACTGAATTATTAACAGCCTATGAGCGTTTACTCCTGGATTTATT
AAAAGGTGACGCCACACTTTTTGCCCGAAGCGACGCAGTACGGGCCTGTTGGGATTTTGTTCAGCCCATTTTAGACTATC
AAAAAAAATCATTTCCTCTGCATGGATATGCGTCTGGCACGTGGGGGCCGATTGAAGCGGAAAAATTATTAAACCGAGAT
AACCATGAATGGCGCTTCCCCTGTAAAAATTTAACCGATACAGATTACTGTGAGTTATAA

Upstream 100 bases:

>100_bases
ATAAAATCTCAAGTTACAATAATCTGTTCAGGTATTCGCAACCTCAGATTAAACTGCACGTTACATTTGCGCTAAATATT
TTGTTATATAAGGACTCTCA

Downstream 100 bases:

>100_bases
AATGAATTATACAATTTTTTCTGCAACCCAATTACTGCTAGATAAACTGGCCGAGGATTTTTTGCTCTTAAGTCAAAAAG
AGACCGTAAGCCATATCTCT

Product: glucose-6-phosphate 1-dehydrogenase

Products: NA

Alternate protein names: G6PD [H]

Number of amino acids: Translated: 499; Mature: 498

Protein sequence:

>499_residues
MSVIDTSCIVIFGASGDLTQRMLIPALYHLYVDQKLPKSFAILGVSRSIYSDQAFRSKLIKNIKSDKKINEELLNKFCEH
LFYQAINTSDVNDYTLLKKRISRINADRELKNNTLFYLATPPSLYSVIPEHLAAVGLNEETDGWKRLVVEKPFGSDLKSA
VSLDESLYRHFQEQQIYRIDHYLGKETVQNMLVLRFANSIFEPLWNGRYIDYVEVTGAEALGVEQRGGYYDGSGAMRDML
QNHLLQVIAMVAMEPPAVINAKSMRDEVVKVLQCLKPLSQDDLENNLVLGQYIQSQVRGKCLPAYREEEGVPNNSRTETY
VGLKLFINNWRWDGVPFYLRTGKRLPTRVTEVVIHFKKTPHPVFSADAPENKLIIRIQPDEGIMLGFGLKEPGAGFDAKE
VAMDFHYSDLKETELLTAYERLLLDLLKGDATLFARSDAVRACWDFVQPILDYQKKSFPLHGYASGTWGPIEAEKLLNRD
NHEWRFPCKNLTDTDYCEL

Sequences:

>Translated_499_residues
MSVIDTSCIVIFGASGDLTQRMLIPALYHLYVDQKLPKSFAILGVSRSIYSDQAFRSKLIKNIKSDKKINEELLNKFCEH
LFYQAINTSDVNDYTLLKKRISRINADRELKNNTLFYLATPPSLYSVIPEHLAAVGLNEETDGWKRLVVEKPFGSDLKSA
VSLDESLYRHFQEQQIYRIDHYLGKETVQNMLVLRFANSIFEPLWNGRYIDYVEVTGAEALGVEQRGGYYDGSGAMRDML
QNHLLQVIAMVAMEPPAVINAKSMRDEVVKVLQCLKPLSQDDLENNLVLGQYIQSQVRGKCLPAYREEEGVPNNSRTETY
VGLKLFINNWRWDGVPFYLRTGKRLPTRVTEVVIHFKKTPHPVFSADAPENKLIIRIQPDEGIMLGFGLKEPGAGFDAKE
VAMDFHYSDLKETELLTAYERLLLDLLKGDATLFARSDAVRACWDFVQPILDYQKKSFPLHGYASGTWGPIEAEKLLNRD
NHEWRFPCKNLTDTDYCEL
>Mature_498_residues
SVIDTSCIVIFGASGDLTQRMLIPALYHLYVDQKLPKSFAILGVSRSIYSDQAFRSKLIKNIKSDKKINEELLNKFCEHL
FYQAINTSDVNDYTLLKKRISRINADRELKNNTLFYLATPPSLYSVIPEHLAAVGLNEETDGWKRLVVEKPFGSDLKSAV
SLDESLYRHFQEQQIYRIDHYLGKETVQNMLVLRFANSIFEPLWNGRYIDYVEVTGAEALGVEQRGGYYDGSGAMRDMLQ
NHLLQVIAMVAMEPPAVINAKSMRDEVVKVLQCLKPLSQDDLENNLVLGQYIQSQVRGKCLPAYREEEGVPNNSRTETYV
GLKLFINNWRWDGVPFYLRTGKRLPTRVTEVVIHFKKTPHPVFSADAPENKLIIRIQPDEGIMLGFGLKEPGAGFDAKEV
AMDFHYSDLKETELLTAYERLLLDLLKGDATLFARSDAVRACWDFVQPILDYQKKSFPLHGYASGTWGPIEAEKLLNRDN
HEWRFPCKNLTDTDYCEL

Specific function: Pentose phosphate pathway; first step. [C]

COG id: COG0364

COG function: function code G; Glucose-6-phosphate 1-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-6-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI108773793, Length=481, Percent_Identity=38.8773388773389, Blast_Score=331, Evalue=1e-90,
Organism=Homo sapiens, GI109389365, Length=481, Percent_Identity=38.8773388773389, Blast_Score=331, Evalue=1e-90,
Organism=Homo sapiens, GI52145310, Length=481, Percent_Identity=29.1060291060291, Blast_Score=168, Evalue=1e-41,
Organism=Escherichia coli, GI1788158, Length=499, Percent_Identity=41.8837675350701, Blast_Score=372, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17538218, Length=482, Percent_Identity=38.1742738589212, Blast_Score=322, Evalue=3e-88,
Organism=Saccharomyces cerevisiae, GI6324088, Length=501, Percent_Identity=34.1317365269461, Blast_Score=285, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24643352, Length=485, Percent_Identity=37.5257731958763, Blast_Score=313, Evalue=2e-85,
Organism=Drosophila melanogaster, GI24643350, Length=485, Percent_Identity=37.5257731958763, Blast_Score=312, Evalue=3e-85,
Organism=Drosophila melanogaster, GI221513548, Length=481, Percent_Identity=31.6008316008316, Blast_Score=226, Evalue=4e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001282
- InterPro:   IPR019796
- InterPro:   IPR022675
- InterPro:   IPR022674
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02781 G6PD_C; PF00479 G6PD_N [H]

EC number: =1.1.1.49 [H]

Molecular weight: Translated: 57042; Mature: 56911

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00069 G6P_DEHYDROGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVIDTSCIVIFGASGDLTQRMLIPALYHLYVDQKLPKSFAILGVSRSIYSDQAFRSKLI
CCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHEEEECHHHHHHHHHHHHHHH
KNIKSDKKINEELLNKFCEHLFYQAINTSDVNDYTLLKKRISRINADRELKNNTLFYLAT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHCCCEEEEEEC
PPSLYSVIPEHLAAVGLNEETDGWKRLVVEKPFGSDLKSAVSLDESLYRHFQEQQIYRID
CHHHHHHHHHHHHHCCCCCCCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HYLGKETVQNMLVLRFANSIFEPLWNGRYIDYVEVTGAEALGVEQRGGYYDGSGAMRDML
HHHCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHCCCCCCCCEECCCHHHHHHH
QNHLLQVIAMVAMEPPAVINAKSMRDEVVKVLQCLKPLSQDDLENNLVLGQYIQSQVRGK
HHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHCCCCCCHHCCCCCHHHHHHHHHCCC
CLPAYREEEGVPNNSRTETYVGLKLFINNWRWDGVPFYLRTGKRLPTRVTEVVIHFKKTP
CCCCHHHHCCCCCCCCCHHEEEEEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHCCCC
HPVFSADAPENKLIIRIQPDEGIMLGFGLKEPGAGFDAKEVAMDFHYSDLKETELLTAYE
CCCEECCCCCCEEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHH
RLLLDLLKGDATLFARSDAVRACWDFVQPILDYQKKSFPLHGYASGTWGPIEAEKLLNRD
HHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCC
NHEWRFPCKNLTDTDYCEL
CCCEECCCCCCCCCCCCCC
>Mature Secondary Structure 
SVIDTSCIVIFGASGDLTQRMLIPALYHLYVDQKLPKSFAILGVSRSIYSDQAFRSKLI
CCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHEEEECHHHHHHHHHHHHHHH
KNIKSDKKINEELLNKFCEHLFYQAINTSDVNDYTLLKKRISRINADRELKNNTLFYLAT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHCCCEEEEEEC
PPSLYSVIPEHLAAVGLNEETDGWKRLVVEKPFGSDLKSAVSLDESLYRHFQEQQIYRID
CHHHHHHHHHHHHHCCCCCCCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
HYLGKETVQNMLVLRFANSIFEPLWNGRYIDYVEVTGAEALGVEQRGGYYDGSGAMRDML
HHHCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHCCCCCCCCEECCCHHHHHHH
QNHLLQVIAMVAMEPPAVINAKSMRDEVVKVLQCLKPLSQDDLENNLVLGQYIQSQVRGK
HHHHHHHHHHHHCCCCCEECHHHHHHHHHHHHHHHCCCCCCHHCCCCCHHHHHHHHHCCC
CLPAYREEEGVPNNSRTETYVGLKLFINNWRWDGVPFYLRTGKRLPTRVTEVVIHFKKTP
CCCCHHHHCCCCCCCCCHHEEEEEEEEECCCCCCCCEEEECCCCCHHHHHHHHHHHCCCC
HPVFSADAPENKLIIRIQPDEGIMLGFGLKEPGAGFDAKEVAMDFHYSDLKETELLTAYE
CCCEECCCCCCEEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHH
RLLLDLLKGDATLFARSDAVRACWDFVQPILDYQKKSFPLHGYASGTWGPIEAEKLLNRD
HHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCC
NHEWRFPCKNLTDTDYCEL
CCCEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]