Click here to switch to the map view.

The map label for this gene is ptsG [H]

Identifier: 119946354

GI number: 119946354

Start: 3342223

End: 3343629

Strand: Direct

Name: ptsG [H]

Synonym: Ping_2725

Alternate gene names: 119946354

Gene position: 3342223-3343629 (Clockwise)

Preceding gene: 119946353

Following gene: 119946357

Centisome position: 73.3

GC content: 41.44

Gene sequence:

>1407_bases
ATGAACATTTTCGGAAATTTACAAAAAGTAGGGAAGTCATTAATGCTTCCTGTCTCTGTACTGCCTATAGCGGGTATTTT
ACTCGGTGTGGGTGCTGCAAAGTTCTCGATATTACCTGATGTTATTTCGCAACTGATGGAACAGGCTGGCGGTGCAGTAT
TTGGTAATATGGCACTTATTTTTGCAATTGGTGTTGCATTAGGATTTACAAAAAATGATGGTGTAGCGGGTCTTGCTGCT
GTTGTTGGTTATGTGATCATGATGAAAACAATTGAAGTACTTGCTCCTGGCGCAAATACAGGTGTACTGGGTGGTATCGT
CGCCGGTGGTATTGCTGCTGCCATGTTCAACCGCTTCTACAATATTAAGTTACCTGATTACTTAGGTTTCTTTGCCGGTA
AACGTGCCGTCCCTATTATGACTGGTTTTGTTGCTATCATTATAGGTGCAATTCTTTCTGTTGTTTGGCCTCCCGTTGGT
AATGGTATTGCTGCTTTCTCACATTGGGCTGCAGAACAAAATCCGACACTCGCATTTGGTATTTACGGTGTTGTTGAACG
TTCATTAATCCCCTTTGGTCTTCACCATATCTGGAATGTACCCTTCTTCTTTGAAGCAGGTAGTTGTGTAAACAATGCCG
GTGAGCAACTAAACGGTGTATTAACATGTTACCTGTCTGCCAATGATGCAACGCGTGCTGCAGGTAATGGTTTTGGTCAA
TTAGCGGGTGGTTACATGTTTAAAATGTACGGTCTACCTGCTGCTGCTATCGCGATTGCACATTCAGCTAAGCCTGAAAA
CCGCGCTAAAGTCATGGGTATCATGGTTTCTGCTGCGTTAACTTCATTCTTAACCGGTATTACTGAACCAATCGAATTTG
CATTCCTATTCGTAGCGCCAGTTTTATATGCAATCCATGCGCTATTAGCGGGTTCTGCATTTGTTGTTACTAATATGTTA
GGTATGGTACACGGTACTTCATTCTCACATGGTCTGATTGATTTCTTGGTACTCTCTGCTAATTCACAAAAATTCCTGTG
GTTCCCAGCAATAGGCCTTATTTACGCAGCAATCTACTACACTGTATTCCGTGTTCTTATTGCGAAGTTGGACCTTAAAA
CACCTGGCCGTGAAGATGAAGAACTTGAGCAAGAACTTGCACTTGATAGCACTGAAATGTCTATTCTTCTTGTTGCGGCA
TTCGGTGGTAAAGTGAATATTGATAGCTTGGATGCTTGTATTACACGTTTACGTATCAGTGTTAAAGATATATCACTAGT
AGATAAAGCTGAACTTAAGAGATTAGGTGCTGCCGGTGTGGTCGTATCAGGTAACGGAGTTCAAGCTATCTTCGGTACTA
AATCTGATAACTTAAAAACAGATATGGAAAATTACATGTCTAAATAG

Upstream 100 bases:

>100_bases
TCATCACTAACATCTTCTATATACTCCGCCTAAATAGAATTGAAATCTTTTAGGCTTATTGTTTATTTTAAGTCAAATTT
AACCTCTAGGAGAATTGTGT

Downstream 100 bases:

>100_bases
TAAGTTGTCGGGCAGCTGTTTCACCTGCCCGCGCTTTAAAGTAGAAGCTTAACAATTTATAACACTGTTTATTTGTTAAG
CTTCGACTTATTACTCTAAC

Product: PTS system glucose-specific transporter subunits IIBC

Products: NA

Alternate protein names: EIICB-Glc; EII-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component [H]

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MNIFGNLQKVGKSLMLPVSVLPIAGILLGVGAAKFSILPDVISQLMEQAGGAVFGNMALIFAIGVALGFTKNDGVAGLAA
VVGYVIMMKTIEVLAPGANTGVLGGIVAGGIAAAMFNRFYNIKLPDYLGFFAGKRAVPIMTGFVAIIIGAILSVVWPPVG
NGIAAFSHWAAEQNPTLAFGIYGVVERSLIPFGLHHIWNVPFFFEAGSCVNNAGEQLNGVLTCYLSANDATRAAGNGFGQ
LAGGYMFKMYGLPAAAIAIAHSAKPENRAKVMGIMVSAALTSFLTGITEPIEFAFLFVAPVLYAIHALLAGSAFVVTNML
GMVHGTSFSHGLIDFLVLSANSQKFLWFPAIGLIYAAIYYTVFRVLIAKLDLKTPGREDEELEQELALDSTEMSILLVAA
FGGKVNIDSLDACITRLRISVKDISLVDKAELKRLGAAGVVVSGNGVQAIFGTKSDNLKTDMENYMSK

Sequences:

>Translated_468_residues
MNIFGNLQKVGKSLMLPVSVLPIAGILLGVGAAKFSILPDVISQLMEQAGGAVFGNMALIFAIGVALGFTKNDGVAGLAA
VVGYVIMMKTIEVLAPGANTGVLGGIVAGGIAAAMFNRFYNIKLPDYLGFFAGKRAVPIMTGFVAIIIGAILSVVWPPVG
NGIAAFSHWAAEQNPTLAFGIYGVVERSLIPFGLHHIWNVPFFFEAGSCVNNAGEQLNGVLTCYLSANDATRAAGNGFGQ
LAGGYMFKMYGLPAAAIAIAHSAKPENRAKVMGIMVSAALTSFLTGITEPIEFAFLFVAPVLYAIHALLAGSAFVVTNML
GMVHGTSFSHGLIDFLVLSANSQKFLWFPAIGLIYAAIYYTVFRVLIAKLDLKTPGREDEELEQELALDSTEMSILLVAA
FGGKVNIDSLDACITRLRISVKDISLVDKAELKRLGAAGVVVSGNGVQAIFGTKSDNLKTDMENYMSK
>Mature_468_residues
MNIFGNLQKVGKSLMLPVSVLPIAGILLGVGAAKFSILPDVISQLMEQAGGAVFGNMALIFAIGVALGFTKNDGVAGLAA
VVGYVIMMKTIEVLAPGANTGVLGGIVAGGIAAAMFNRFYNIKLPDYLGFFAGKRAVPIMTGFVAIIIGAILSVVWPPVG
NGIAAFSHWAAEQNPTLAFGIYGVVERSLIPFGLHHIWNVPFFFEAGSCVNNAGEQLNGVLTCYLSANDATRAAGNGFGQ
LAGGYMFKMYGLPAAAIAIAHSAKPENRAKVMGIMVSAALTSFLTGITEPIEFAFLFVAPVLYAIHALLAGSAFVVTNML
GMVHGTSFSHGLIDFLVLSANSQKFLWFPAIGLIYAAIYYTVFRVLIAKLDLKTPGREDEELEQELALDSTEMSILLVAA
FGGKVNIDSLDACITRLRISVKDISLVDKAELKRLGAAGVVVSGNGVQAIFGTKSDNLKTDMENYMSK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=479, Percent_Identity=66.5970772442589, Blast_Score=620, Evalue=1e-179,
Organism=Escherichia coli, GI1786894, Length=481, Percent_Identity=40.956340956341, Blast_Score=312, Evalue=4e-86,
Organism=Escherichia coli, GI1787908, Length=519, Percent_Identity=35.8381502890173, Blast_Score=274, Evalue=1e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 49304; Mature: 49304

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIFGNLQKVGKSLMLPVSVLPIAGILLGVGAAKFSILPDVISQLMEQAGGAVFGNMALI
CCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
FAIGVALGFTKNDGVAGLAAVVGYVIMMKTIEVLAPGANTGVLGGIVAGGIAAAMFNRFY
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
NIKLPDYLGFFAGKRAVPIMTGFVAIIIGAILSVVWPPVGNGIAAFSHWAAEQNPTLAFG
CCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEH
IYGVVERSLIPFGLHHIWNVPFFFEAGSCVNNAGEQLNGVLTCYLSANDATRAAGNGFGQ
HHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCEEEEEEECCCCCHHCCCCCHH
LAGGYMFKMYGLPAAAIAIAHSAKPENRAKVMGIMVSAALTSFLTGITEPIEFAFLFVAP
HHCCCEEHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VLYAIHALLAGSAFVVTNMLGMVHGTSFSHGLIDFLVLSANSQKFLWFPAIGLIYAAIYY
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHEEECCCCEEEEHHHHHHHHHHHHH
TVFRVLIAKLDLKTPGREDEELEQELALDSTEMSILLVAAFGGKVNIDSLDACITRLRIS
HHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHH
VKDISLVDKAELKRLGAAGVVVSGNGVQAIFGTKSDNLKTDMENYMSK
HHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MNIFGNLQKVGKSLMLPVSVLPIAGILLGVGAAKFSILPDVISQLMEQAGGAVFGNMALI
CCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
FAIGVALGFTKNDGVAGLAAVVGYVIMMKTIEVLAPGANTGVLGGIVAGGIAAAMFNRFY
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
NIKLPDYLGFFAGKRAVPIMTGFVAIIIGAILSVVWPPVGNGIAAFSHWAAEQNPTLAFG
CCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCEEEH
IYGVVERSLIPFGLHHIWNVPFFFEAGSCVNNAGEQLNGVLTCYLSANDATRAAGNGFGQ
HHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCEEEEEEECCCCCHHCCCCCHH
LAGGYMFKMYGLPAAAIAIAHSAKPENRAKVMGIMVSAALTSFLTGITEPIEFAFLFVAP
HHCCCEEHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
VLYAIHALLAGSAFVVTNMLGMVHGTSFSHGLIDFLVLSANSQKFLWFPAIGLIYAAIYY
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHEEECCCCEEEEHHHHHHHHHHHHH
TVFRVLIAKLDLKTPGREDEELEQELALDSTEMSILLVAAFGGKVNIDSLDACITRLRIS
HHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHH
VKDISLVDKAELKRLGAAGVVVSGNGVQAIFGTKSDNLKTDMENYMSK
HHHHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]