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The map label for this gene is intA [H]

Identifier: 119946114

GI number: 119946114

Start: 3015302

End: 3015952

Strand: Reverse

Name: intA [H]

Synonym: Ping_2464

Alternate gene names: 119946114

Gene position: 3015952-3015302 (Counterclockwise)

Preceding gene: 119946116

Following gene: 119946111

Centisome position: 66.15

GC content: 31.95

Gene sequence:

>651_bases
ATGTACAAAATAAGATTAATTAAAGGCGAAAAAATGAAAAAAACAGCTCCGCTAACTGAACAAGAGATTGAAGGGGCAAC
ACCAAAAGAAAAAGAATATAACCTTGGTGATGGTAATGGGCTTTATTTGTACGTTCGACCCAAAGGAACAAAATCTTGGA
AATATAATTACACCCATCCATATACTAAAAAAAGAGCAAATCTTGGATTAGGCGTTTATCCAAATGTTACTCTTGAGCAA
GCTAGAATGGTGAGGGATGAATTTAACTCTTTGTTAGCGAATAATATTGATCCTAAAAAACATCGAGATGCGAAGATAAA
AGAAGAAACTGAAGTTAATCAGTACCTTTTTGATAATGTAGTTAATGACTGGCTTAAAGTTAAAGCTTCTGAACTTAAAC
CGCTTGGCTTAAAAAGAATAACTAATTCATTAGATAATTTTATTTTACCGTTTGTGGCAAATTGTTCAGTTAAAGACATT
AACGCTAAGTTGGTAATGGAAGTGTTACAACCGATCAAGAAAAATGGTGATATACAAGTGTTGATGCAAAACCATCTCTA
TTTTTATCAAATAATGGATTATGCAAAATCAAGTGGGTTAATAGATCATAACCCACTCAATAAACTTAATGTTGCTATTA
GCGACATTTAA

Upstream 100 bases:

>100_bases
GGCACTAGAAATAATTCTATTTGCTTATTTATTGAATTTATAAAGAGGGCTTATTATCGAATAATTAATGATATTATTTA
TTTAGTTCTTGATCTGAAAT

Downstream 100 bases:

>100_bases
TAAGACTTACCATTATTTTTTGTATTGGTTAATTAACAATCTTTAGCGCTTTTAATCCGGTGATTGAGTTAGATCCTTTC
GATGCCTCTTCAATATGATC

Product: phage integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MYKIRLIKGEKMKKTAPLTEQEIEGATPKEKEYNLGDGNGLYLYVRPKGTKSWKYNYTHPYTKKRANLGLGVYPNVTLEQ
ARMVRDEFNSLLANNIDPKKHRDAKIKEETEVNQYLFDNVVNDWLKVKASELKPLGLKRITNSLDNFILPFVANCSVKDI
NAKLVMEVLQPIKKNGDIQVLMQNHLYFYQIMDYAKSSGLIDHNPLNKLNVAISDI

Sequences:

>Translated_216_residues
MYKIRLIKGEKMKKTAPLTEQEIEGATPKEKEYNLGDGNGLYLYVRPKGTKSWKYNYTHPYTKKRANLGLGVYPNVTLEQ
ARMVRDEFNSLLANNIDPKKHRDAKIKEETEVNQYLFDNVVNDWLKVKASELKPLGLKRITNSLDNFILPFVANCSVKDI
NAKLVMEVLQPIKKNGDIQVLMQNHLYFYQIMDYAKSSGLIDHNPLNKLNVAISDI
>Mature_216_residues
MYKIRLIKGEKMKKTAPLTEQEIEGATPKEKEYNLGDGNGLYLYVRPKGTKSWKYNYTHPYTKKRANLGLGVYPNVTLEQ
ARMVRDEFNSLLANNIDPKKHRDAKIKEETEVNQYLFDNVVNDWLKVKASELKPLGLKRITNSLDNFILPFVANCSVKDI
NAKLVMEVLQPIKKNGDIQVLMQNHLYFYQIMDYAKSSGLIDHNPLNKLNVAISDI

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=193, Percent_Identity=34.1968911917098, Blast_Score=134, Evalue=3e-33,
Organism=Escherichia coli, GI145693166, Length=206, Percent_Identity=31.0679611650485, Blast_Score=91, Evalue=4e-20,
Organism=Escherichia coli, GI1788690, Length=196, Percent_Identity=29.5918367346939, Blast_Score=80, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 24863; Mature: 24863

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKIRLIKGEKMKKTAPLTEQEIEGATPKEKEYNLGDGNGLYLYVRPKGTKSWKYNYTHP
CEEEEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEECCCCC
YTKKRANLGLGVYPNVTLEQARMVRDEFNSLLANNIDPKKHRDAKIKEETEVNQYLFDNV
CCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
VNDWLKVKASELKPLGLKRITNSLDNFILPFVANCSVKDINAKLVMEVLQPIKKNGDIQV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEE
LMQNHLYFYQIMDYAKSSGLIDHNPLNKLNVAISDI
EEECCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECC
>Mature Secondary Structure
MYKIRLIKGEKMKKTAPLTEQEIEGATPKEKEYNLGDGNGLYLYVRPKGTKSWKYNYTHP
CEEEEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEECCCCC
YTKKRANLGLGVYPNVTLEQARMVRDEFNSLLANNIDPKKHRDAKIKEETEVNQYLFDNV
CCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHH
VNDWLKVKASELKPLGLKRITNSLDNFILPFVANCSVKDINAKLVMEVLQPIKKNGDIQV
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCEEE
LMQNHLYFYQIMDYAKSSGLIDHNPLNKLNVAISDI
EEECCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]