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The map label for this gene is grxD [H]

Identifier: 119946099

GI number: 119946099

Start: 2996199

End: 2996537

Strand: Direct

Name: grxD [H]

Synonym: Ping_2449

Alternate gene names: 119946099

Gene position: 2996199-2996537 (Clockwise)

Preceding gene: 119946097

Following gene: 119946102

Centisome position: 65.71

GC content: 40.71

Gene sequence:

>339_bases
ATGGAAACATTAGATAAAATCAAAAGCCAAATCAGTGAAAATACAGTATTGCTTTACATGAAAGGCTCGCCAAAATTACC
CAGCTGCGGCTTTTCATCACAGGCTTCTCAAGCACTAATGCAATGTGGTCACCCTTTTGCTTACGTAGATATTCTACAAA
ACCCAGATATTCGCGCAGAGCTACCAAAATATGCAAACTGGCCAACCTTCCCACAACTATGGATCGCTGGTGAGTTAGTA
GGTGGTTGCGATATTATCATGGAAATGTCACAACAAGGTGAATTAAAACCTATTGTTGAACAAGCAGTTGCTGCAACAGC
AACAGCTGAGTCAGAATAA

Upstream 100 bases:

>100_bases
GTTTATGATAAAGTAGATTTAATTAGTCCATATTTATAAAGCATTCTGACTGTGCTAGAGTATGGGCACGATCCCAATAA
CATAATTACCGGATATAAAA

Downstream 100 bases:

>100_bases
AGGCTGAATCACACCAGAAAAAAGGGATACTGAATGTATCCCTTTTTTATTGTCTAAGAATAAACGCGACGTCAGCACAA
TATTAAACTGAAAAGTCATA

Product: glutaredoxin-like protein

Products: NA

Alternate protein names: Grx4; Monothiol glutaredoxin [H]

Number of amino acids: Translated: 112; Mature: 112

Protein sequence:

>112_residues
METLDKIKSQISENTVLLYMKGSPKLPSCGFSSQASQALMQCGHPFAYVDILQNPDIRAELPKYANWPTFPQLWIAGELV
GGCDIIMEMSQQGELKPIVEQAVAATATAESE

Sequences:

>Translated_112_residues
METLDKIKSQISENTVLLYMKGSPKLPSCGFSSQASQALMQCGHPFAYVDILQNPDIRAELPKYANWPTFPQLWIAGELV
GGCDIIMEMSQQGELKPIVEQAVAATATAESE
>Mature_112_residues
METLDKIKSQISENTVLLYMKGSPKLPSCGFSSQASQALMQCGHPFAYVDILQNPDIRAELPKYANWPTFPQLWIAGELV
GGCDIIMEMSQQGELKPIVEQAVAATATAESE

Specific function: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters [H]

COG id: COG0278

COG function: function code O; Glutaredoxin-related protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI95113651, Length=95, Percent_Identity=42.1052631578947, Blast_Score=94, Evalue=2e-20,
Organism=Homo sapiens, GI42516576, Length=92, Percent_Identity=38.0434782608696, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1787943, Length=110, Percent_Identity=69.0909090909091, Blast_Score=170, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI71988153, Length=84, Percent_Identity=40.4761904761905, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17556042, Length=100, Percent_Identity=31, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71988159, Length=83, Percent_Identity=37.3493975903614, Blast_Score=77, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325198, Length=114, Percent_Identity=36.8421052631579, Blast_Score=89, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6321022, Length=73, Percent_Identity=50.6849315068493, Blast_Score=87, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6320303, Length=73, Percent_Identity=50.6849315068493, Blast_Score=84, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24642023, Length=93, Percent_Identity=43.010752688172, Blast_Score=95, Evalue=7e-21,
Organism=Drosophila melanogaster, GI19921242, Length=92, Percent_Identity=36.9565217391304, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002109
- InterPro:   IPR014434
- InterPro:   IPR004480
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 12247; Mature: 12247

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METLDKIKSQISENTVLLYMKGSPKLPSCGFSSQASQALMQCGHPFAYVDILQNPDIRAE
CCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCC
LPKYANWPTFPQLWIAGELVGGCDIIMEMSQQGELKPIVEQAVAATATAESE
CCCCCCCCCCCHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
METLDKIKSQISENTVLLYMKGSPKLPSCGFSSQASQALMQCGHPFAYVDILQNPDIRAE
CCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCC
LPKYANWPTFPQLWIAGELVGGCDIIMEMSQQGELKPIVEQAVAATATAESE
CCCCCCCCCCCHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]