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The map label for this gene is crr [H]

Identifier: 119946091

GI number: 119946091

Start: 2990162

End: 2990671

Strand: Direct

Name: crr [H]

Synonym: Ping_2441

Alternate gene names: 119946091

Gene position: 2990162-2990671 (Clockwise)

Preceding gene: 119946090

Following gene: 119946092

Centisome position: 65.58

GC content: 36.27

Gene sequence:

>510_bases
ATGGGTTTTTTTGATTCATTAAAAAAAGCGGTTTCAGGTAACACTGCAACTGAAAACACAATCAATCTGATTGCGCCAAT
TTCTGGTGAAATTGTAGCGATTGAAGATGTGCCTGATGTTGTTTTTGCTGAAAAAATAGTGGGTGATGGTATTGCCATTC
GTCCTACCGGCAACAAAATGGTTGCTCCTTGTGACGGAACAATTGGTAAAATATTTGAAACAAATCATGCATTCTCGCTT
GAATCTGACACGGGTATTGAGCTTTTTGTGCATTTCGGTATTGATACTGTTGAGCTGAAAGGTAAAGGTTTTACACGTAT
TGCTGAAGAAGGCCAAAAAGTAAAAATGGGTGATACCATTATTGAGTTTGATCTTGCATTTCTGACTGAAAAAGCAAAAT
CAATCCTGACGCCTATTGTTATCTCAAACATGGATGAAATTAAAGAACTGCAAAAAATGTCTGGTACTGTTGTAGTTGGA
ATTGATCCTGTCCTTAAAATAGTTAAATAA

Upstream 100 bases:

>100_bases
AAAGGTATTAACTAAATATTTAAACGAACTACAATGTATATAAAAACAAAAATAGTTCATTTAAAAAATATAACTATTAA
CAATAATAGGGAGTTCGACT

Downstream 100 bases:

>100_bases
ACGAAATTTTTTTAACTTTTAAAAGAGTCGCTGATGCGACTCTTTTAGTTTCTGTGCTGATCTTATTATTATTAATTGTT
ACAATATTTTAACTATTATT

Product: PTS system glucose-specific transporter subunit

Products: protein histidine; sugar phosphate

Alternate protein names: EIIA-Glc; EIII-Glc; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MGFFDSLKKAVSGNTATENTINLIAPISGEIVAIEDVPDVVFAEKIVGDGIAIRPTGNKMVAPCDGTIGKIFETNHAFSL
ESDTGIELFVHFGIDTVELKGKGFTRIAEEGQKVKMGDTIIEFDLAFLTEKAKSILTPIVISNMDEIKELQKMSGTVVVG
IDPVLKIVK

Sequences:

>Translated_169_residues
MGFFDSLKKAVSGNTATENTINLIAPISGEIVAIEDVPDVVFAEKIVGDGIAIRPTGNKMVAPCDGTIGKIFETNHAFSL
ESDTGIELFVHFGIDTVELKGKGFTRIAEEGQKVKMGDTIIEFDLAFLTEKAKSILTPIVISNMDEIKELQKMSGTVVVG
IDPVLKIVK
>Mature_168_residues
GFFDSLKKAVSGNTATENTINLIAPISGEIVAIEDVPDVVFAEKIVGDGIAIRPTGNKMVAPCDGTIGKIFETNHAFSLE
SDTGIELFVHFGIDTVELKGKGFTRIAEEGQKVKMGDTIIEFDLAFLTEKAKSILTPIVISNMDEIKELQKMSGTVVVGI
DPVLKIVK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG2190

COG function: function code G; Phosphotransferase system IIA components

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788757, Length=169, Percent_Identity=76.9230769230769, Blast_Score=259, Evalue=9e-71,
Organism=Escherichia coli, GI1786894, Length=148, Percent_Identity=50, Blast_Score=152, Evalue=1e-38,
Organism=Escherichia coli, GI1790159, Length=147, Percent_Identity=37.4149659863946, Blast_Score=108, Evalue=1e-25,

Paralogues:

None

Copy number: 3540 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 140 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR001127 [H]

Pfam domain/function: PF00358 PTS_EIIA_1 [H]

EC number: 2.7.1.69

Molecular weight: Translated: 18155; Mature: 18024

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS00371 PTS_EIIA_TYPE_1_HIS ; PS51093 PTS_EIIA_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFFDSLKKAVSGNTATENTINLIAPISGEIVAIEDVPDVVFAEKIVGDGIAIRPTGNKM
CCHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHCCCEEEEECCCEE
VAPCDGTIGKIFETNHAFSLESDTGIELFVHFGIDTVELKGKGFTRIAEEGQKVKMGDTI
EECCCCCCHHEEECCCEEEECCCCCEEEEEEECCEEEEECCCCCHHHHHCCCEEECCCEE
IEFDLAFLTEKAKSILTPIVISNMDEIKELQKMSGTVVVGIDPVLKIVK
EEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEECHHHHHHCC
>Mature Secondary Structure 
GFFDSLKKAVSGNTATENTINLIAPISGEIVAIEDVPDVVFAEKIVGDGIAIRPTGNKM
CHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEECCCCHHHHHHHHCCCEEEEECCCEE
VAPCDGTIGKIFETNHAFSLESDTGIELFVHFGIDTVELKGKGFTRIAEEGQKVKMGDTI
EECCCCCCHHEEECCCEEEECCCCCEEEEEEECCEEEEECCCCCHHHHHCCCEEECCCEE
IEFDLAFLTEKAKSILTPIVISNMDEIKELQKMSGTVVVGIDPVLKIVK
EEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEECHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups; Phosphotransferases with an alcohol group as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]