Click here to switch to the map view.

The map label for this gene is pucG [H]

Identifier: 119946075

GI number: 119946075

Start: 2971803

End: 2973035

Strand: Reverse

Name: pucG [H]

Synonym: Ping_2424

Alternate gene names: 119946075

Gene position: 2973035-2971803 (Counterclockwise)

Preceding gene: 119946076

Following gene: 119946074

Centisome position: 65.2

GC content: 47.12

Gene sequence:

>1233_bases
ATGAGCACCAGCGACCTTTTTGAAACCCTTGATCCACCGCAGCGTTTACTAATGGGGCCTGGCCCAATTAATGCTTATCC
GCGTGTACATCAAGCTATTTCAGCGTCACTGATTGGTCAGTATGATCCGGTGATGACAGGTTATATGAATCAGGTGCAAT
CTTTGTATCGTGGTGTGTTTGAGACGAATAACCAGCAAACATTACTGGTTAATGGTACCGCGCGTTCGGGCATTGAAGCG
GTATTAGTGTCGGTATTACAACCGGGGGATAAAGTATTAATCCCGGTAATAGGACGTTTTGGCCATTTGCTGTGCGAAAT
AGCGAAACGTGTTGGTGCACAAGTAAAAACCATTGATATTGAATGGGGTGAAGTGTGCTCGCCGGAGCAAGTGGAAAAAG
CGATTAAAGCATTTCAACCAAAACTGTTCGCCACGGTGCAGGGTGATACTTCGACGACCATGAATCAACCTTTGGCGGAA
ATTGGCGAAATTTGTCAACGCCACGGCGTCTTATTCTACTGTGATGCCACCGCCTCTATTGCCGGCAATGAGCTGAAAAT
AGATGAATGGCATCTTGATGCTGTATCCGTGGGCCTGCAGAAATGTCTAGGAGGGCCATCGGGCAGCGCACCCATTACCT
TAAGTGATCGCTGTGCCGAGGTTATTAATCGCCGCAAACATATTGAGGCAGGTATTCGTGCCGCTCATCATGTTGAGGGC
TGTGATGCGATGATTCAATCTAACTATTTTGATCTGGCGATGATCATGGATTACTGGGGCCCTGAGCGTTTGAACCATCA
CACGGAATCAACCAGCATGTTATATGCAGCACGTGAATGTGCGCGTCTTTTTCTCGAAGAAGGGGTGGATAAAGTGATTG
CCCGTCATCAACAAGCGGGTGATGCAATGGCATCCGGCCTGCAGGCAATGGGCTTAACCTTATTTGGGAATCAGCAATAT
AAAATGAATAACGTGGTCGGTGTGTATATTCCACAGGGTATTGATGGCGATAAAGTGCGTCAGCAACTCCAGCAGCGTTT
TGGTATTGAAATTGGCACTTCGTTTGGGCCCTTACATGGCAAGGTTTGGCGTATTGGCACTATGGGTTATAACGCCCGGC
AGGATTGTGTTTTAACGACTTTGGTGGCGTTGGAATCTATTTTATTAAAATATAAAGTGAAGGTTAGTTCAGGTCAGGCG
GTGTTAGCTGCGATGGCGCACTACCGCGATTAA

Upstream 100 bases:

>100_bases
TAATGGGGCACGCCGGTGCAATTGTTATAGACTCGCAAGGTCTAGCCTGTGCAAGCAGCGATCCCCGCAGTGATGGAAGC
AGTTTACTTGGAGATGTTTT

Downstream 100 bases:

>100_bases
ATGAACAATGGTAAATATGGAAAAGGAGACGCTATGATAATGGAAGATGGCGCCAGAAAAATTATGCAACAATCTGATCA
GCTTGCTGTATTCAGCTCAA

Product: Serine--pyruvate transaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MSTSDLFETLDPPQRLLMGPGPINAYPRVHQAISASLIGQYDPVMTGYMNQVQSLYRGVFETNNQQTLLVNGTARSGIEA
VLVSVLQPGDKVLIPVIGRFGHLLCEIAKRVGAQVKTIDIEWGEVCSPEQVEKAIKAFQPKLFATVQGDTSTTMNQPLAE
IGEICQRHGVLFYCDATASIAGNELKIDEWHLDAVSVGLQKCLGGPSGSAPITLSDRCAEVINRRKHIEAGIRAAHHVEG
CDAMIQSNYFDLAMIMDYWGPERLNHHTESTSMLYAARECARLFLEEGVDKVIARHQQAGDAMASGLQAMGLTLFGNQQY
KMNNVVGVYIPQGIDGDKVRQQLQQRFGIEIGTSFGPLHGKVWRIGTMGYNARQDCVLTTLVALESILLKYKVKVSSGQA
VLAAMAHYRD

Sequences:

>Translated_410_residues
MSTSDLFETLDPPQRLLMGPGPINAYPRVHQAISASLIGQYDPVMTGYMNQVQSLYRGVFETNNQQTLLVNGTARSGIEA
VLVSVLQPGDKVLIPVIGRFGHLLCEIAKRVGAQVKTIDIEWGEVCSPEQVEKAIKAFQPKLFATVQGDTSTTMNQPLAE
IGEICQRHGVLFYCDATASIAGNELKIDEWHLDAVSVGLQKCLGGPSGSAPITLSDRCAEVINRRKHIEAGIRAAHHVEG
CDAMIQSNYFDLAMIMDYWGPERLNHHTESTSMLYAARECARLFLEEGVDKVIARHQQAGDAMASGLQAMGLTLFGNQQY
KMNNVVGVYIPQGIDGDKVRQQLQQRFGIEIGTSFGPLHGKVWRIGTMGYNARQDCVLTTLVALESILLKYKVKVSSGQA
VLAAMAHYRD
>Mature_409_residues
STSDLFETLDPPQRLLMGPGPINAYPRVHQAISASLIGQYDPVMTGYMNQVQSLYRGVFETNNQQTLLVNGTARSGIEAV
LVSVLQPGDKVLIPVIGRFGHLLCEIAKRVGAQVKTIDIEWGEVCSPEQVEKAIKAFQPKLFATVQGDTSTTMNQPLAEI
GEICQRHGVLFYCDATASIAGNELKIDEWHLDAVSVGLQKCLGGPSGSAPITLSDRCAEVINRRKHIEAGIRAAHHVEGC
DAMIQSNYFDLAMIMDYWGPERLNHHTESTSMLYAARECARLFLEEGVDKVIARHQQAGDAMASGLQAMGLTLFGNQQYK
MNNVVGVYIPQGIDGDKVRQQLQQRFGIEIGTSFGPLHGKVWRIGTMGYNARQDCVLTTLVALESILLKYKVKVSSGQAV
LAAMAHYRD

Specific function: Could encode ureidoglycolase or L-alanine:glyoxylate aminotransferase, or perhaps both activities [H]

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=387, Percent_Identity=32.0413436692506, Blast_Score=202, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI17536281, Length=371, Percent_Identity=34.5013477088949, Blast_Score=224, Evalue=6e-59,
Organism=Saccharomyces cerevisiae, GI6321079, Length=378, Percent_Identity=23.2804232804233, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI17530823, Length=393, Percent_Identity=34.0966921119593, Blast_Score=238, Evalue=7e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 44934; Mature: 44803

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSDLFETLDPPQRLLMGPGPINAYPRVHQAISASLIGQYDPVMTGYMNQVQSLYRGVF
CCCHHHHHHCCCHHHHEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ETNNQQTLLVNGTARSGIEAVLVSVLQPGDKVLIPVIGRFGHLLCEIAKRVGAQVKTIDI
CCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCEEEEEEE
EWGEVCSPEQVEKAIKAFQPKLFATVQGDTSTTMNQPLAEIGEICQRHGVLFYCDATASI
CCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHCCHHHHHHHHHHHCCEEEEECCCCCC
AGNELKIDEWHLDAVSVGLQKCLGGPSGSAPITLSDRCAEVINRRKHIEAGIRAAHHVEG
CCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
CDAMIQSNYFDLAMIMDYWGPERLNHHTESTSMLYAARECARLFLEEGVDKVIARHQQAG
HHHHHHCCCHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAMASGLQAMGLTLFGNQQYKMNNVVGVYIPQGIDGDKVRQQLQQRFGIEIGTSFGPLHG
HHHHHHHHHHCEEEECCCCEEECCEEEEEECCCCCHHHHHHHHHHHHCEEECCCCCCCCC
KVWRIGTMGYNARQDCVLTTLVALESILLKYKVKVSSGQAVLAAMAHYRD
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHCC
>Mature Secondary Structure 
STSDLFETLDPPQRLLMGPGPINAYPRVHQAISASLIGQYDPVMTGYMNQVQSLYRGVF
CCHHHHHHCCCHHHHEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ETNNQQTLLVNGTARSGIEAVLVSVLQPGDKVLIPVIGRFGHLLCEIAKRVGAQVKTIDI
CCCCCEEEEEECCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCEEEEEEE
EWGEVCSPEQVEKAIKAFQPKLFATVQGDTSTTMNQPLAEIGEICQRHGVLFYCDATASI
CCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCHHCCHHHHHHHHHHHCCEEEEECCCCCC
AGNELKIDEWHLDAVSVGLQKCLGGPSGSAPITLSDRCAEVINRRKHIEAGIRAAHHVEG
CCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
CDAMIQSNYFDLAMIMDYWGPERLNHHTESTSMLYAARECARLFLEEGVDKVIARHQQAG
HHHHHHCCCHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAMASGLQAMGLTLFGNQQYKMNNVVGVYIPQGIDGDKVRQQLQQRFGIEIGTSFGPLHG
HHHHHHHHHHCEEEECCCCEEECCEEEEEECCCCCHHHHHHHHHHHHCEEECCCCCCCCC
KVWRIGTMGYNARQDCVLTTLVALESILLKYKVKVSSGQAVLAAMAHYRD
CEEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11344136 [H]