Click here to switch to the map view.

The map label for this gene is gapA [H]

Identifier: 119946023

GI number: 119946023

Start: 2883131

End: 2884123

Strand: Direct

Name: gapA [H]

Synonym: Ping_2367

Alternate gene names: 119946023

Gene position: 2883131-2884123 (Clockwise)

Preceding gene: 119946022

Following gene: 119946035

Centisome position: 63.23

GC content: 41.69

Gene sequence:

>993_bases
ATGACAATTAAAGTAGGTATTAACGGTTTCGGTCGTATCGGACGCTTCGTATTCCGTGCAGCATGTGAACGTACTGATAT
TGATGTTGTAGCAATCAATGACTTAATCGATGTTGATTATATGGCTTACATGCTTAAATATGACTCAACTCATGGTCGTT
TTAACGGTACTGTTGAAGTTCAAGACGGTAACCTAATTGTTAACGGTAAAACAGTTCGCGTAACTGCAGTCCGTAACCCT
GAAGAACTAAAATGGGATGAAGCTGGCGTTGATGTAGTTGCTGAAGCAACTGGTCTTTTCCTAACTGACGAAACAGCTCG
TAAGCACATTACTGCTGGCGCTAAAAAAGTTGTTTTAACAGGTCCTTCTGGCGATGTTCCAATGTTCGTTAACGGCGTAA
ACTTCTCTGCATACGCGGGTCAAGATATCGTTTCTAACGCTTCTTGTACTACTAACTGTCTTGCACCTATCGCTAAAGTA
CTTAACGATAAATGGGGCATTGAATCTGGTCTTATGACGACAGTTCATGCAACTACTGCAACGCAAAAAACCGTTGACGG
ACCTTCTGTTAAAGATTGGCGCGGTGGTCGTGGTGCTTCTCAAAACATCATCCCATCATCAACTGGTGCTGCTAAGGCAG
TAGGTAAAGTAATCCCAGCGCTTGATGGCAAACTAACGGGTATGGCTTTCCGTGTACCAACCGCAAACGTTTCTGTTGTT
GACTTAACTGTTAACCTTAAAACAGCTGCTACTTATGCTGAAATCTGTGCTGAAATGAAGCGTGCTTCTGAAAATGAATA
CGCTGGTGTTCTTGGTTACACAGCAGATGCTGTTGTTTCTCAAGATTTCATCGGTGAAACTCAAACTTCAGTATTTGATT
CTACTGCAGGCGTTTCACTCACTGACAAATTCGTTAAAGTTGTATCTTGGTACGACAACGAAATCGGTTACTCAAACAAA
GTTCTTGACCTAATCACACTTATTGCTAAATAA

Upstream 100 bases:

>100_bases
CTAACACCAAGTAACTTGACTAACATCAAGCCTTTGGTGTCAGTGGCATTTACAATAAACACAGTTTTTAAAATCAAACC
ATCCAAAAGGATCTATAAAA

Downstream 100 bases:

>100_bases
GTTTAATTAGTCGATATTTGTTTTAAGCCTGTACTTCGGTATGGGCTTTTTTGTGTCTGAAATTTGCCCAATATAAATTC
GTCATTAAATTCCGTATCTT

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH-A [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTIKVGINGFGRIGRFVFRAACERTDIDVVAINDLIDVDYMAYMLKYDSTHGRFNGTVEVQDGNLIVNGKTVRVTAVRNP
EELKWDEAGVDVVAEATGLFLTDETARKHITAGAKKVVLTGPSGDVPMFVNGVNFSAYAGQDIVSNASCTTNCLAPIAKV
LNDKWGIESGLMTTVHATTATQKTVDGPSVKDWRGGRGASQNIIPSSTGAAKAVGKVIPALDGKLTGMAFRVPTANVSVV
DLTVNLKTAATYAEICAEMKRASENEYAGVLGYTADAVVSQDFIGETQTSVFDSTAGVSLTDKFVKVVSWYDNEIGYSNK
VLDLITLIAK

Sequences:

>Translated_330_residues
MTIKVGINGFGRIGRFVFRAACERTDIDVVAINDLIDVDYMAYMLKYDSTHGRFNGTVEVQDGNLIVNGKTVRVTAVRNP
EELKWDEAGVDVVAEATGLFLTDETARKHITAGAKKVVLTGPSGDVPMFVNGVNFSAYAGQDIVSNASCTTNCLAPIAKV
LNDKWGIESGLMTTVHATTATQKTVDGPSVKDWRGGRGASQNIIPSSTGAAKAVGKVIPALDGKLTGMAFRVPTANVSVV
DLTVNLKTAATYAEICAEMKRASENEYAGVLGYTADAVVSQDFIGETQTSVFDSTAGVSLTDKFVKVVSWYDNEIGYSNK
VLDLITLIAK
>Mature_329_residues
TIKVGINGFGRIGRFVFRAACERTDIDVVAINDLIDVDYMAYMLKYDSTHGRFNGTVEVQDGNLIVNGKTVRVTAVRNPE
ELKWDEAGVDVVAEATGLFLTDETARKHITAGAKKVVLTGPSGDVPMFVNGVNFSAYAGQDIVSNASCTTNCLAPIAKVL
NDKWGIESGLMTTVHATTATQKTVDGPSVKDWRGGRGASQNIIPSSTGAAKAVGKVIPALDGKLTGMAFRVPTANVSVVD
LTVNLKTAATYAEICAEMKRASENEYAGVLGYTADAVVSQDFIGETQTSVFDSTAGVSLTDKFVKVVSWYDNEIGYSNKV
LDLITLIAK

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=329, Percent_Identity=60.4863221884498, Blast_Score=414, Evalue=1e-116,
Organism=Homo sapiens, GI7657116, Length=329, Percent_Identity=57.7507598784195, Blast_Score=396, Evalue=1e-110,
Organism=Escherichia coli, GI1788079, Length=331, Percent_Identity=79.7583081570997, Blast_Score=535, Evalue=1e-153,
Organism=Escherichia coli, GI1789295, Length=329, Percent_Identity=41.3373860182371, Blast_Score=247, Evalue=9e-67,
Organism=Caenorhabditis elegans, GI32566163, Length=333, Percent_Identity=60.0600600600601, Blast_Score=399, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17568413, Length=333, Percent_Identity=60.0600600600601, Blast_Score=399, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17534677, Length=334, Percent_Identity=58.3832335329341, Blast_Score=384, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17534679, Length=334, Percent_Identity=58.0838323353293, Blast_Score=384, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6322409, Length=330, Percent_Identity=63.030303030303, Blast_Score=424, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6321631, Length=330, Percent_Identity=62.4242424242424, Blast_Score=417, Evalue=1e-117,
Organism=Saccharomyces cerevisiae, GI6322468, Length=330, Percent_Identity=61.8181818181818, Blast_Score=414, Evalue=1e-116,
Organism=Drosophila melanogaster, GI85725000, Length=327, Percent_Identity=62.9969418960245, Blast_Score=417, Evalue=1e-117,
Organism=Drosophila melanogaster, GI22023983, Length=327, Percent_Identity=62.9969418960245, Blast_Score=417, Evalue=1e-117,
Organism=Drosophila melanogaster, GI17933600, Length=327, Percent_Identity=62.3853211009174, Blast_Score=416, Evalue=1e-116,
Organism=Drosophila melanogaster, GI18110149, Length=327, Percent_Identity=62.3853211009174, Blast_Score=416, Evalue=1e-116,
Organism=Drosophila melanogaster, GI19922412, Length=323, Percent_Identity=57.2755417956656, Blast_Score=372, Evalue=1e-103,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35137; Mature: 35006

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKVGINGFGRIGRFVFRAACERTDIDVVAINDLIDVDYMAYMLKYDSTHGRFNGTVEV
CEEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHEECCCCCEECCEEEE
QDGNLIVNGKTVRVTAVRNPEELKWDEAGVDVVAEATGLFLTDETARKHITAGAKKVVLT
ECCCEEECCCEEEEEEECCCHHCCCCCCCCEEEECCCCEEEECHHHHHHHCCCCCEEEEE
GPSGDVPMFVNGVNFSAYAGQDIVSNASCTTNCLAPIAKVLNDKWGIESGLMTTVHATTA
CCCCCCCEEEECCCCEEECCCHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCC
TQKTVDGPSVKDWRGGRGASQNIIPSSTGAAKAVGKVIPALDGKLTGMAFRVPTANVSVV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCEEEE
DLTVNLKTAATYAEICAEMKRASENEYAGVLGYTADAVVSQDFIGETQTSVFDSTAGVSL
EEEEEEHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHCCCCHHHHHCCCCCCCH
TDKFVKVVSWYDNEIGYSNKVLDLITLIAK
HHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
TIKVGINGFGRIGRFVFRAACERTDIDVVAINDLIDVDYMAYMLKYDSTHGRFNGTVEV
EEEEECCCHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHEECCCCCEECCEEEE
QDGNLIVNGKTVRVTAVRNPEELKWDEAGVDVVAEATGLFLTDETARKHITAGAKKVVLT
ECCCEEECCCEEEEEEECCCHHCCCCCCCCEEEECCCCEEEECHHHHHHHCCCCCEEEEE
GPSGDVPMFVNGVNFSAYAGQDIVSNASCTTNCLAPIAKVLNDKWGIESGLMTTVHATTA
CCCCCCCEEEECCCCEEECCCHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCC
TQKTVDGPSVKDWRGGRGASQNIIPSSTGAAKAVGKVIPALDGKLTGMAFRVPTANVSVV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCEEEE
DLTVNLKTAATYAEICAEMKRASENEYAGVLGYTADAVVSQDFIGETQTSVFDSTAGVSL
EEEEEEHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHCCCCHHHHHCCCCCCCH
TDKFVKVVSWYDNEIGYSNKVLDLITLIAK
HHHHHHHHHHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]