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The map label for this gene is sdcS [H]

Identifier: 119945999

GI number: 119945999

Start: 2845598

End: 2847016

Strand: Reverse

Name: sdcS [H]

Synonym: Ping_2341

Alternate gene names: 119945999

Gene position: 2847016-2845598 (Counterclockwise)

Preceding gene: 119946000

Following gene: 119945998

Centisome position: 62.44

GC content: 40.1

Gene sequence:

>1419_bases
ATGTTAAAGCGGAATTTAAAGTATACTTTACCTATTTTACTGCCATTAATTGTGCTTTTATTACCTGCTGACAGTTTTGC
TCTTGACGGTTTAACATTGGTAGAGCAGCGGGTGATTGCTATTTTTGTTATGGCTACGCTATGTTGGGTTTTAGAGCCAA
TTCCTATCTACGCCACTTCCGTTTTAATTATTGTCTTAGAACTGTTACTTATCTCGGACAATGGATTATGGTTCGCAACT
AACAGTGCTCCTGAACAACAAGGGCAGTTGCTCAGTCAAACTGCCATTATGGCAACCTTTGCATCGCCTATTATTATGCT
CTTTTTAGGTGGTTTCTTTTTAGCGCTGGCGGCTACCAAATACCGTTTAGATATTAATTTAGCACGCGTATTATTACGTC
CTTTTGGCTACAATCCTAAGTATGTAATGCTTGGTATTATGCTTATTACCGCCGTGTTTTCTATGTTTATGAGTAATACA
GCAACCACCGCCATGATGCTGTCTATTTTAACACCGGTGCTGGCGTTATTTGCCGCTGAAGATTTGGGTAAGGTCGCATT
TGCTTTATCGGTCCCTGTCGCGGCTAATATAGGGGGTATAGCAACCCCGATTGGTACTCCACCTAATGCAGTCGCACTTA
AATATTTAGTGAATGAAAACAGTATTAGTTTTGCTGAATGGATGTCGATCGGTGTGCCTTTTGTGGTGGTGATGTTATTT
ATCGCCTGGTTATTATTAATAAAACTATTTCCAACATCAACTCAGCAAATCGATTTAAATATTGAAGGAATATTTTTAAA
AACACCTAAAGCCTGGTTAGTTTACGGCACCTTTTTGTTGACCATTTTATTGTGGTTGATGGGAAACCTGCATGGAATGA
GTTCCTATGTGGTCGCAATGCTCCCCGTTGCGATATTCTCCATCTTTAATATTATCAACAAAGAAGATTTAAAAAATATT
CCATGGGACGTCTTGTGGTTGGTCTCTGGTGGTATAGCATTAGGGTTGGCACTTGATAAAACAGGACTGGCTGCCCATGT
AGTTGATGCTATCCCCTTTAATAATTTCCATCCTCTGCTTTTGATTGTTGGGGCATCCATGCTGTGTTTACTGATGGCTA
ACTTTATGTCCAATACGGCCACCGCAAACCTTTTATTACCTTTGGTTGCTACATTGGGTGCTTCGATGCATTCATTACTA
CCCTATGGCGGGCAAGTGGTACTCATTCTTTCAGTAACGTTCTCCGCATCATTAGGTATGTCATTACCGGTCAGCACGCC
ACCGAATGCACTTGCTTATGCTTCAGGTCATATTGAAACCAAGCAGATGGCAAAAATCGGCATTATTATTGGTATTATTG
GTATATCAGTCGCCTTTGCTATGTTATTCATTATGAATAAAGCCCATTTTATTGGCTAA

Upstream 100 bases:

>100_bases
GCAATCACATCAATAATGAATAAAGCTATACTTTAACGGTAGGTGTTACAACTGATAACTCTACCCTGCCTGAAGTACCA
CTTTATTAAAGGATTATTGA

Downstream 100 bases:

>100_bases
GTCATTTTTTGTTAAGCAATTTAATTTGAGAAAGAAAAATGGAAAAAATTAATATTATTTGTGTTGATGATGAACGTGAC
GTCTTGGAATCGGTCAGCCG

Product: anion transporter

Products: NA

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MLKRNLKYTLPILLPLIVLLLPADSFALDGLTLVEQRVIAIFVMATLCWVLEPIPIYATSVLIIVLELLLISDNGLWFAT
NSAPEQQGQLLSQTAIMATFASPIIMLFLGGFFLALAATKYRLDINLARVLLRPFGYNPKYVMLGIMLITAVFSMFMSNT
ATTAMMLSILTPVLALFAAEDLGKVAFALSVPVAANIGGIATPIGTPPNAVALKYLVNENSISFAEWMSIGVPFVVVMLF
IAWLLLIKLFPTSTQQIDLNIEGIFLKTPKAWLVYGTFLLTILLWLMGNLHGMSSYVVAMLPVAIFSIFNIINKEDLKNI
PWDVLWLVSGGIALGLALDKTGLAAHVVDAIPFNNFHPLLLIVGASMLCLLMANFMSNTATANLLLPLVATLGASMHSLL
PYGGQVVLILSVTFSASLGMSLPVSTPPNALAYASGHIETKQMAKIGIIIGIIGISVAFAMLFIMNKAHFIG

Sequences:

>Translated_472_residues
MLKRNLKYTLPILLPLIVLLLPADSFALDGLTLVEQRVIAIFVMATLCWVLEPIPIYATSVLIIVLELLLISDNGLWFAT
NSAPEQQGQLLSQTAIMATFASPIIMLFLGGFFLALAATKYRLDINLARVLLRPFGYNPKYVMLGIMLITAVFSMFMSNT
ATTAMMLSILTPVLALFAAEDLGKVAFALSVPVAANIGGIATPIGTPPNAVALKYLVNENSISFAEWMSIGVPFVVVMLF
IAWLLLIKLFPTSTQQIDLNIEGIFLKTPKAWLVYGTFLLTILLWLMGNLHGMSSYVVAMLPVAIFSIFNIINKEDLKNI
PWDVLWLVSGGIALGLALDKTGLAAHVVDAIPFNNFHPLLLIVGASMLCLLMANFMSNTATANLLLPLVATLGASMHSLL
PYGGQVVLILSVTFSASLGMSLPVSTPPNALAYASGHIETKQMAKIGIIIGIIGISVAFAMLFIMNKAHFIG
>Mature_472_residues
MLKRNLKYTLPILLPLIVLLLPADSFALDGLTLVEQRVIAIFVMATLCWVLEPIPIYATSVLIIVLELLLISDNGLWFAT
NSAPEQQGQLLSQTAIMATFASPIIMLFLGGFFLALAATKYRLDINLARVLLRPFGYNPKYVMLGIMLITAVFSMFMSNT
ATTAMMLSILTPVLALFAAEDLGKVAFALSVPVAANIGGIATPIGTPPNAVALKYLVNENSISFAEWMSIGVPFVVVMLF
IAWLLLIKLFPTSTQQIDLNIEGIFLKTPKAWLVYGTFLLTILLWLMGNLHGMSSYVVAMLPVAIFSIFNIINKEDLKNI
PWDVLWLVSGGIALGLALDKTGLAAHVVDAIPFNNFHPLLLIVGASMLCLLMANFMSNTATANLLLPLVATLGASMHSLL
PYGGQVVLILSVTFSASLGMSLPVSTPPNALAYASGHIETKQMAKIGIIIGIIGISVAFAMLFIMNKAHFIG

Specific function: Mediates the transport of dicarboxylates across the cytoplasmic membrane via a Na(+)-electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=540, Percent_Identity=26.1111111111111, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI301069349, Length=295, Percent_Identity=25.7627118644068, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI301069353, Length=330, Percent_Identity=23.6363636363636, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI58761541, Length=330, Percent_Identity=23.6363636363636, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI31377715, Length=143, Percent_Identity=30.7692307692308, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI301069346, Length=143, Percent_Identity=30.7692307692308, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI219802232, Length=462, Percent_Identity=24.4588744588745, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI31795546, Length=334, Percent_Identity=24.8502994011976, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI19923838, Length=145, Percent_Identity=29.6551724137931, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1786829, Length=468, Percent_Identity=24.1452991452991, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32565804, Length=429, Percent_Identity=29.3706293706294, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71988385, Length=466, Percent_Identity=28.755364806867, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI71989118, Length=520, Percent_Identity=25.1923076923077, Blast_Score=101, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6324340, Length=421, Percent_Identity=29.6912114014252, Blast_Score=147, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6322263, Length=410, Percent_Identity=28.2926829268293, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6319885, Length=410, Percent_Identity=28.780487804878, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281362116, Length=527, Percent_Identity=22.9601518026565, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281362114, Length=527, Percent_Identity=22.9601518026565, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI281362112, Length=527, Percent_Identity=22.9601518026565, Blast_Score=86, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 50927; Mature: 50927

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRNLKYTLPILLPLIVLLLPADSFALDGLTLVEQRVIAIFVMATLCWVLEPIPIYATS
CCCCCCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
VLIIVLELLLISDNGLWFATNSAPEQQGQLLSQTAIMATFASPIIMLFLGGFFLALAATK
HHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRLDINLARVLLRPFGYNPKYVMLGIMLITAVFSMFMSNTATTAMMLSILTPVLALFAAE
HEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
DLGKVAFALSVPVAANIGGIATPIGTPPNAVALKYLVNENSISFAEWMSIGVPFVVVMLF
HHHHHHHHEECCHHCCCCCCCCCCCCCCCHHEEEEEECCCCCCHHHHHHCCHHHHHHHHH
IAWLLLIKLFPTSTQQIDLNIEGIFLKTPKAWLVYGTFLLTILLWLMGNLHGMSSYVVAM
HHHHHHHHHCCCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LPVAIFSIFNIINKEDLKNIPWDVLWLVSGGIALGLALDKTGLAAHVVDAIPFNNFHPLL
HHHHHHHHHHHHCHHHHCCCCHHHHHHHHCCEEEEEEECCCCHHHHHHHHCCCCCCCHHH
LIVGASMLCLLMANFMSNTATANLLLPLVATLGASMHSLLPYGGQVVLILSVTFSASLGM
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHCCCC
SLPVSTPPNALAYASGHIETKQMAKIGIIIGIIGISVAFAMLFIMNKAHFIG
CCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLKRNLKYTLPILLPLIVLLLPADSFALDGLTLVEQRVIAIFVMATLCWVLEPIPIYATS
CCCCCCCHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
VLIIVLELLLISDNGLWFATNSAPEQQGQLLSQTAIMATFASPIIMLFLGGFFLALAATK
HHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YRLDINLARVLLRPFGYNPKYVMLGIMLITAVFSMFMSNTATTAMMLSILTPVLALFAAE
HEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
DLGKVAFALSVPVAANIGGIATPIGTPPNAVALKYLVNENSISFAEWMSIGVPFVVVMLF
HHHHHHHHEECCHHCCCCCCCCCCCCCCCHHEEEEEECCCCCCHHHHHHCCHHHHHHHHH
IAWLLLIKLFPTSTQQIDLNIEGIFLKTPKAWLVYGTFLLTILLWLMGNLHGMSSYVVAM
HHHHHHHHHCCCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LPVAIFSIFNIINKEDLKNIPWDVLWLVSGGIALGLALDKTGLAAHVVDAIPFNNFHPLL
HHHHHHHHHHHHCHHHHCCCCHHHHHHHHCCEEEEEEECCCCHHHHHHHHCCCCCCCHHH
LIVGASMLCLLMANFMSNTATANLLLPLVATLGASMHSLLPYGGQVVLILSVTFSASLGM
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEHHHCCCC
SLPVSTPPNALAYASGHIETKQMAKIGIIIGIIGISVAFAMLFIMNKAHFIG
CCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA