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The map label for this gene is dnaX [H]

Identifier: 119945937

GI number: 119945937

Start: 2764117

End: 2766441

Strand: Reverse

Name: dnaX [H]

Synonym: Ping_2277

Alternate gene names: 119945937

Gene position: 2766441-2764117 (Counterclockwise)

Preceding gene: 119945938

Following gene: 119945936

Centisome position: 60.67

GC content: 42.37

Gene sequence:

>2325_bases
GTGAGTTATCAAGTTTTAGCACGAAAATGGCGACCAGGTAATTTCCAGGAAGTGGTTGGCCAGCAACATGTGTTGACCGC
TTTATCTAATAGTTTGGCGCAAAACAGATTACACCATGCTTATCTGTTCAGTGGTACCCGCGGTGTAGGTAAAACGACCA
TTGCACGTATTTTGGCAAAAAGCCTGAATTGTGAAAAGGGGGTGACGGCAACACCCTGTGGCGCATGTGTACATTGTCAG
GCTATTGATCAGGGGCGTTTTGTTGATTTATTAGAAATAGATGCCGCTTCCCGTACTAAGGTCGATGATACGCGTGAAAT
GCTTGATAATGTTCAATATAAACCTGCACAGGGGCGTTATAAAGTTTATCTTATTGACGAAGTGCATATGCTCTCCAAGC
ACAGCTTTAATGCTTTGCTAAAAACATTGGAAGAGCCGCCTGAATATGTGAAGTTTTTATTAGCCACGACAGACCCACAA
AAATTACCCATTACGGTATTATCTCGTTGTCTACAATTTCACTTAAAAGCGATTTTGCCGCAAGAAATTGAAACCCAATT
AGCTTATATTCTGAACCATGAGCAGGCGACGTTTGAGCATGCTGCGCTGACTGTTATTGCCACGGCAGCAGAGGGCAGTA
TGCGGGATGCGTTAAGTTTGACTGACCAGGCACTGGCTTTTGGCTCTGGCCACATTGCATACCAGTCTGTATTAAAGATG
CTTGGCTCTATTGACAACAATCATTTGCATTATTTATTACACTTTATTGCTTCCGGAAATGTTTCAAAAGTCTTCCTGAA
AATAGATGAATTTGTGCATCTTGGGGCAGATTTTGCCATGTTACACCAAACCTTAGCCAGTTTGTGTCATGAAATTGCAC
TATCACAGATGCAGCCTAAACAGAATGTAACCCAAAAATCTGCCGTACAATTATTAGCAGAACGTTTAACGCCCGAAGAG
GTGCAGCTTTATTATCAAATTGCTGTTCAGGGCTATAAAGATTACGCTTTTGCACCTAACGGTAAAATTGCTTTTGAGAT
GACGGTGATGCGTCTGCTTGCCTTTAAACCCGCAAATTATATCAGTTTGGATGAGCGGCAACTTGGTAATCCGAATAGCG
CGGAAGCAAGTGATGCGCAGCAGAGTAATATCGCAGCGGCTTCAGAATCGGTCGAATCTGTAGAAATAGCAGAAGCCCCT
GTGATAGAAAACTTGCAGCAAAACCCGGCAGCGTCGCAAATAGTGCAACAGGAGCCTAAAAGCGCAGATTCAGTTCAGTC
GACGTCTCCCTCTGTCGAGCCATTACAGAGATCAGCTGCGTCTTCGGTGCCGCCCCCAATTGAAAGACAACCAGAGCCGC
AGCAGAATCAGTCTGCACCGCCCAGTGAAAAAATAGCACCTGTTGCTGAGGTCTCTCATTCTCGAAATATGTTACGTAGT
CATAGATTAAAACGAGAAAGCGCAAAAAAGAACCAGGCGACAACTACTGAACAACCTGCCTCAGTTGTCGCATCCGGGGC
GGAAAATGTAACAGCAGAGTTTAAAGCTGATAAGTATCAGATGAGTGGCATTGATGAGGATATCAGCAGCACGCCAGATC
TTCAGGGAGTTAATCGAAACAATGCTATTGCTGATAATCTATCAGCAATACAAGATAATAGGGTCGATCAAGAGATAATC
CCCCTTGAATCTTATCAGCAGGATCAGTTTGTACCGGATAGTGACAATCAAGAACAGCCGGCAGACTATCTTAGTCAAAC
AATGAGTGCTGATTATGGTGAAAGCCGTGGACCGGAAAATATCCTGGAGAATAAGCGGGAGGAAAAAGAACCTGCTGTTG
CGGAGAATAAAGATAAAAGTAGCACTTTTCTATCAGATAATATCTTTGTTAATGATGATATTGAACGAGCGGAAATTGAT
CCCGGCAAATATGTGGCAGACAAATTAAGCGATCCCTGGGCATTAGCTATTCAGAAAATGCGCTTAGTCGGTTTAGTGAA
GTTATTAGCCAAAAATAGCGTCATGAAAATAGTTGAACAGCAAATTGTATTGACCTTAAAACCTGAACAACAACACTTAC
TCAATAACCATCAATTATGCACACAATTAGAGACAAAATTAAAAGTTCATTTTGGGGCGCAAATGAGCATGTATGTTGAA
GTGGGGCATGTCACTGGCAAGTTAACCGCATTTGAGTCGGAATTGGCTATTTATCAAACCTATTTGAATAATGCAAAAAC
GGCTATTAAAGAAGATCAAAACATTCTAACTTTTGTCAGTGAATACGGCGCAAAGGTCTACGAAAATAGCATCATACCGT
TATAA

Upstream 100 bases:

>100_bases
CTTTTGTTATTGAATTGCCGGCCTTAAAAGGGGCGCAAAAACTGCACGCACTTAATGTTCCGTATTTTTCCTTAATCAAA
TTTGAAGGTGAGTAATTTTT

Downstream 100 bases:

>100_bases
TCTGATACTATATTTTATATGTTAATCCATCAAAAAGAGAAGTGATATGTTTAGTAAAGAAGGCATGGGCGATTTAATGA
AAAAAGCCCAAGAGATGCAA

Product: DNA polymerase III, subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 774; Mature: 773

Protein sequence:

>774_residues
MSYQVLARKWRPGNFQEVVGQQHVLTALSNSLAQNRLHHAYLFSGTRGVGKTTIARILAKSLNCEKGVTATPCGACVHCQ
AIDQGRFVDLLEIDAASRTKVDDTREMLDNVQYKPAQGRYKVYLIDEVHMLSKHSFNALLKTLEEPPEYVKFLLATTDPQ
KLPITVLSRCLQFHLKAILPQEIETQLAYILNHEQATFEHAALTVIATAAEGSMRDALSLTDQALAFGSGHIAYQSVLKM
LGSIDNNHLHYLLHFIASGNVSKVFLKIDEFVHLGADFAMLHQTLASLCHEIALSQMQPKQNVTQKSAVQLLAERLTPEE
VQLYYQIAVQGYKDYAFAPNGKIAFEMTVMRLLAFKPANYISLDERQLGNPNSAEASDAQQSNIAAASESVESVEIAEAP
VIENLQQNPAASQIVQQEPKSADSVQSTSPSVEPLQRSAASSVPPPIERQPEPQQNQSAPPSEKIAPVAEVSHSRNMLRS
HRLKRESAKKNQATTTEQPASVVASGAENVTAEFKADKYQMSGIDEDISSTPDLQGVNRNNAIADNLSAIQDNRVDQEII
PLESYQQDQFVPDSDNQEQPADYLSQTMSADYGESRGPENILENKREEKEPAVAENKDKSSTFLSDNIFVNDDIERAEID
PGKYVADKLSDPWALAIQKMRLVGLVKLLAKNSVMKIVEQQIVLTLKPEQQHLLNNHQLCTQLETKLKVHFGAQMSMYVE
VGHVTGKLTAFESELAIYQTYLNNAKTAIKEDQNILTFVSEYGAKVYENSIIPL

Sequences:

>Translated_774_residues
MSYQVLARKWRPGNFQEVVGQQHVLTALSNSLAQNRLHHAYLFSGTRGVGKTTIARILAKSLNCEKGVTATPCGACVHCQ
AIDQGRFVDLLEIDAASRTKVDDTREMLDNVQYKPAQGRYKVYLIDEVHMLSKHSFNALLKTLEEPPEYVKFLLATTDPQ
KLPITVLSRCLQFHLKAILPQEIETQLAYILNHEQATFEHAALTVIATAAEGSMRDALSLTDQALAFGSGHIAYQSVLKM
LGSIDNNHLHYLLHFIASGNVSKVFLKIDEFVHLGADFAMLHQTLASLCHEIALSQMQPKQNVTQKSAVQLLAERLTPEE
VQLYYQIAVQGYKDYAFAPNGKIAFEMTVMRLLAFKPANYISLDERQLGNPNSAEASDAQQSNIAAASESVESVEIAEAP
VIENLQQNPAASQIVQQEPKSADSVQSTSPSVEPLQRSAASSVPPPIERQPEPQQNQSAPPSEKIAPVAEVSHSRNMLRS
HRLKRESAKKNQATTTEQPASVVASGAENVTAEFKADKYQMSGIDEDISSTPDLQGVNRNNAIADNLSAIQDNRVDQEII
PLESYQQDQFVPDSDNQEQPADYLSQTMSADYGESRGPENILENKREEKEPAVAENKDKSSTFLSDNIFVNDDIERAEID
PGKYVADKLSDPWALAIQKMRLVGLVKLLAKNSVMKIVEQQIVLTLKPEQQHLLNNHQLCTQLETKLKVHFGAQMSMYVE
VGHVTGKLTAFESELAIYQTYLNNAKTAIKEDQNILTFVSEYGAKVYENSIIPL
>Mature_773_residues
SYQVLARKWRPGNFQEVVGQQHVLTALSNSLAQNRLHHAYLFSGTRGVGKTTIARILAKSLNCEKGVTATPCGACVHCQA
IDQGRFVDLLEIDAASRTKVDDTREMLDNVQYKPAQGRYKVYLIDEVHMLSKHSFNALLKTLEEPPEYVKFLLATTDPQK
LPITVLSRCLQFHLKAILPQEIETQLAYILNHEQATFEHAALTVIATAAEGSMRDALSLTDQALAFGSGHIAYQSVLKML
GSIDNNHLHYLLHFIASGNVSKVFLKIDEFVHLGADFAMLHQTLASLCHEIALSQMQPKQNVTQKSAVQLLAERLTPEEV
QLYYQIAVQGYKDYAFAPNGKIAFEMTVMRLLAFKPANYISLDERQLGNPNSAEASDAQQSNIAAASESVESVEIAEAPV
IENLQQNPAASQIVQQEPKSADSVQSTSPSVEPLQRSAASSVPPPIERQPEPQQNQSAPPSEKIAPVAEVSHSRNMLRSH
RLKRESAKKNQATTTEQPASVVASGAENVTAEFKADKYQMSGIDEDISSTPDLQGVNRNNAIADNLSAIQDNRVDQEIIP
LESYQQDQFVPDSDNQEQPADYLSQTMSADYGESRGPENILENKREEKEPAVAENKDKSSTFLSDNIFVNDDIERAEIDP
GKYVADKLSDPWALAIQKMRLVGLVKLLAKNSVMKIVEQQIVLTLKPEQQHLLNNHQLCTQLETKLKVHFGAQMSMYVEV
GHVTGKLTAFESELAIYQTYLNNAKTAIKEDQNILTFVSEYGAKVYENSIIPL

Specific function: The gamma chain seems to interact with the delta subunit to transfer the beta subunit on the DNA [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=223, Percent_Identity=24.2152466367713, Blast_Score=67, Evalue=8e-11,
Organism=Homo sapiens, GI194306571, Length=226, Percent_Identity=23.8938053097345, Blast_Score=67, Evalue=1e-10,
Organism=Homo sapiens, GI194306567, Length=226, Percent_Identity=23.8938053097345, Blast_Score=67, Evalue=1e-10,
Organism=Escherichia coli, GI1786676, Length=361, Percent_Identity=59.2797783933518, Blast_Score=454, Evalue=1e-129,
Organism=Escherichia coli, GI1787119, Length=191, Percent_Identity=27.7486910994764, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1787341, Length=158, Percent_Identity=32.2784810126582, Blast_Score=66, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17541988, Length=291, Percent_Identity=23.0240549828179, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI17647857, Length=270, Percent_Identity=24.0740740740741, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022001
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12168 DNA_pol3_tau_4; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 85805; Mature: 85674

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQVLARKWRPGNFQEVVGQQHVLTALSNSLAQNRLHHAYLFSGTRGVGKTTIARILAK
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHH
SLNCEKGVTATPCGACVHCQAIDQGRFVDLLEIDAASRTKVDDTREMLDNVQYKPAQGRY
HCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCE
KVYLIDEVHMLSKHSFNALLKTLEEPPEYVKFLLATTDPQKLPITVLSRCLQFHLKAILP
EEEEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCC
QEIETQLAYILNHEQATFEHAALTVIATAAEGSMRDALSLTDQALAFGSGHIAYQSVLKM
HHHHHHHHHHHCCCHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
LGSIDNNHLHYLLHFIASGNVSKVFLKIDEFVHLGADFAMLHQTLASLCHEIALSQMQPK
HHCCCCCHHHHHHHHHHCCCHHEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCH
QNVTQKSAVQLLAERLTPEEVQLYYQIAVQGYKDYAFAPNGKIAFEMTVMRLLAFKPANY
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEECCCCCEEHHHHHHHHHHCCCCCC
ISLDERQLGNPNSAEASDAQQSNIAAASESVESVEIAEAPVIENLQQNPAASQIVQQEPK
EECCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHCCC
SADSVQSTSPSVEPLQRSAASSVPPPIERQPEPQQNQSAPPSEKIAPVAEVSHSRNMLRS
CCCHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHH
HRLKRESAKKNQATTTEQPASVVASGAENVTAEFKADKYQMSGIDEDISSTPDLQGVNRN
HHHHHHHHHCCCCCCCCCCHHHHHCCCCCCEEHHCCCHHHHCCCCCHHCCCCCCCCCCCC
NAIADNLSAIQDNRVDQEIIPLESYQQDQFVPDSDNQEQPADYLSQTMSADYGESRGPEN
CCHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHH
ILENKREEKEPAVAENKDKSSTFLSDNIFVNDDIERAEIDPGKYVADKLSDPWALAIQKM
HHHCCHHHCCCCCCCCCCCCCCEECCCCEECCCCCCCCCCCCHHHHHHCCCHHHHHHHHH
RLVGLVKLLAKNSVMKIVEQQIVLTLKPEQQHLLNNHQLCTQLETKLKVHFGAQMSMYVE
HHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHCCHHHHHHHHHHHEEEECCCEEEEEE
VGHVTGKLTAFESELAIYQTYLNNAKTAIKEDQNILTFVSEYGAKVYENSIIPL
EECCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SYQVLARKWRPGNFQEVVGQQHVLTALSNSLAQNRLHHAYLFSGTRGVGKTTIARILAK
CHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHH
SLNCEKGVTATPCGACVHCQAIDQGRFVDLLEIDAASRTKVDDTREMLDNVQYKPAQGRY
HCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCE
KVYLIDEVHMLSKHSFNALLKTLEEPPEYVKFLLATTDPQKLPITVLSRCLQFHLKAILP
EEEEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCC
QEIETQLAYILNHEQATFEHAALTVIATAAEGSMRDALSLTDQALAFGSGHIAYQSVLKM
HHHHHHHHHHHCCCHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHH
LGSIDNNHLHYLLHFIASGNVSKVFLKIDEFVHLGADFAMLHQTLASLCHEIALSQMQPK
HHCCCCCHHHHHHHHHHCCCHHEEEHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCH
QNVTQKSAVQLLAERLTPEEVQLYYQIAVQGYKDYAFAPNGKIAFEMTVMRLLAFKPANY
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEECCCCCEEHHHHHHHHHHCCCCCC
ISLDERQLGNPNSAEASDAQQSNIAAASESVESVEIAEAPVIENLQQNPAASQIVQQEPK
EECCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHCCC
SADSVQSTSPSVEPLQRSAASSVPPPIERQPEPQQNQSAPPSEKIAPVAEVSHSRNMLRS
CCCHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHH
HRLKRESAKKNQATTTEQPASVVASGAENVTAEFKADKYQMSGIDEDISSTPDLQGVNRN
HHHHHHHHHCCCCCCCCCCHHHHHCCCCCCEEHHCCCHHHHCCCCCHHCCCCCCCCCCCC
NAIADNLSAIQDNRVDQEIIPLESYQQDQFVPDSDNQEQPADYLSQTMSADYGESRGPEN
CCHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHH
ILENKREEKEPAVAENKDKSSTFLSDNIFVNDDIERAEIDPGKYVADKLSDPWALAIQKM
HHHCCHHHCCCCCCCCCCCCCCEECCCCEECCCCCCCCCCCCHHHHHHCCCHHHHHHHHH
RLVGLVKLLAKNSVMKIVEQQIVLTLKPEQQHLLNNHQLCTQLETKLKVHFGAQMSMYVE
HHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHCCHHHHHHHHHHHEEEECCCEEEEEE
VGHVTGKLTAFESELAIYQTYLNNAKTAIKEDQNILTFVSEYGAKVYENSIIPL
EECCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534795; 3018672; 9278503; 2186364; 2187190; 2181440; 1575709 [H]