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The map label for this gene is gph [H]

Identifier: 119945866

GI number: 119945866

Start: 2685914

End: 2686597

Strand: Reverse

Name: gph [H]

Synonym: Ping_2206

Alternate gene names: 119945866

Gene position: 2686597-2685914 (Counterclockwise)

Preceding gene: 119945867

Following gene: 119945863

Centisome position: 58.92

GC content: 41.08

Gene sequence:

>684_bases
ATGCACTCGAATAAACAGTTGCTTGAAAATCCGGAAAATAATAAATATTCAGTGATTATTTTCGATTGGGATGGCACTTT
AATGGACTCCATCGATAAAATCATTAATTGTGTTATACAAGCGGCAAAGCTGAGCGATATACTGGCTCCCTCTCCCCAAG
CCATTCGTGATATTATTGGTCTCAGTTTAGATAAGGCAATGGAGATACTGTTCCCGATGTTATCTCCCGCTAAGCAGCAA
CAACTGATCGATGCATATCGTCATCAATACACCTATTTGAATAAACAGAACACCCCCTTTTATCCGGGTATTAAAGCCTG
GCTAAAGGTGTTAAAACAACAAGGTTACCTGCTCGCAGTTGCCACGGGGAAGGGGCGCAAAGGACTTGATCGACAGCTCT
TGCAATATGAAGTGACTGACTTATTTTCAATTACCTATTGCGCAGACGAAACGCTTTCTAAACCTGACCCTCTGATGCTA
AATAATATACTAGAAGCATTGTCTATCAATGCTGAACAAGCACTGATGATAGGTGACTCTTCTTTTGATCTGGAAATGGC
GAATAATGCTAATGTCGATTGTATTGGGGTGACTTATGGCGTGCACTCCGACGCTGTCTTATCTCAGTACAAGCCCATTG
CTATTTTAAGCGATTTACCCACGCAACTCTGGAAATATATTTAA

Upstream 100 bases:

>100_bases
TACCTTTAAGTACCTTGGGAGCAAAATTAAATGTTAATAGAACCCACTAATAATAGAACCCACTAATAATAGAACCGGTT
ACTAACAGAACGGAGCTTGT

Downstream 100 bases:

>100_bases
GATTCAATCGCTTTGGCGCTGTTGCCAAAGCGATTGACCAGGTTATTTATAAAAATTATTTCCCTTCAATTTTTCTTATT
TGTACAATAATTCCCATCAA

Product: HAD family hydrolase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MHSNKQLLENPENNKYSVIIFDWDGTLMDSIDKIINCVIQAAKLSDILAPSPQAIRDIIGLSLDKAMEILFPMLSPAKQQ
QLIDAYRHQYTYLNKQNTPFYPGIKAWLKVLKQQGYLLAVATGKGRKGLDRQLLQYEVTDLFSITYCADETLSKPDPLML
NNILEALSINAEQALMIGDSSFDLEMANNANVDCIGVTYGVHSDAVLSQYKPIAILSDLPTQLWKYI

Sequences:

>Translated_227_residues
MHSNKQLLENPENNKYSVIIFDWDGTLMDSIDKIINCVIQAAKLSDILAPSPQAIRDIIGLSLDKAMEILFPMLSPAKQQ
QLIDAYRHQYTYLNKQNTPFYPGIKAWLKVLKQQGYLLAVATGKGRKGLDRQLLQYEVTDLFSITYCADETLSKPDPLML
NNILEALSINAEQALMIGDSSFDLEMANNANVDCIGVTYGVHSDAVLSQYKPIAILSDLPTQLWKYI
>Mature_227_residues
MHSNKQLLENPENNKYSVIIFDWDGTLMDSIDKIINCVIQAAKLSDILAPSPQAIRDIIGLSLDKAMEILFPMLSPAKQQ
QLIDAYRHQYTYLNKQNTPFYPGIKAWLKVLKQQGYLLAVATGKGRKGLDRQLLQYEVTDLFSITYCADETLSKPDPLML
NNILEALSINAEQALMIGDSSFDLEMANNANVDCIGVTYGVHSDAVLSQYKPIAILSDLPTQLWKYI

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 25487; Mature: 25487

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHSNKQLLENPENNKYSVIIFDWDGTLMDSIDKIINCVIQAAKLSDILAPSPQAIRDIIG
CCCCCCHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
LSLDKAMEILFPMLSPAKQQQLIDAYRHQYTYLNKQNTPFYPGIKAWLKVLKQQGYLLAV
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHCCCEEEE
ATGKGRKGLDRQLLQYEVTDLFSITYCADETLSKPDPLMLNNILEALSINAEQALMIGDS
ECCCCCCCHHHHHHHHHHHHHHHHHEECHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCC
SFDLEMANNANVDCIGVTYGVHSDAVLSQYKPIAILSDLPTQLWKYI
CCCEEECCCCCEEEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MHSNKQLLENPENNKYSVIIFDWDGTLMDSIDKIINCVIQAAKLSDILAPSPQAIRDIIG
CCCCCCHHCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHC
LSLDKAMEILFPMLSPAKQQQLIDAYRHQYTYLNKQNTPFYPGIKAWLKVLKQQGYLLAV
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHCCCEEEE
ATGKGRKGLDRQLLQYEVTDLFSITYCADETLSKPDPLMLNNILEALSINAEQALMIGDS
ECCCCCCCHHHHHHHHHHHHHHHHHEECHHHCCCCCCHHHHHHHHHHHCCCCCEEEECCC
SFDLEMANNANVDCIGVTYGVHSDAVLSQYKPIAILSDLPTQLWKYI
CCCEEECCCCCEEEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]