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The map label for this gene is ybiC [C]

Identifier: 119945780

GI number: 119945780

Start: 2575306

End: 2576325

Strand: Reverse

Name: ybiC [C]

Synonym: Ping_2116

Alternate gene names: 119945780

Gene position: 2576325-2575306 (Counterclockwise)

Preceding gene: 119945781

Following gene: 119945779

Centisome position: 56.5

GC content: 45.2

Gene sequence:

>1020_bases
ATGAGCCATTTGACTATTAACCTCACCCTTGAAGAAATATACGACCTAGCGAAAACAGCGTTGTTGAGTCAGGGCGCCAA
TGAGGAAAATGCAGCTGCGATCGCAAATACGGTCACTATTGCCGAGAGAGACGGAGCAATTTCTCACGGGCTTTTTCGAA
TTCCTGGCTATATTGTTGGGCTTCAAAGCAAAAAGGTTGTTGGCACAGCAACGCCTGAAATTGAAGAAGTCACACCTATT
ATATTTCGATGTGACGCTAAAAATGGTTATGCACCACTTACACACGAACATTGCTTACCACCATTGATTGATGCCGCTAA
AAAATTCGGACTTGCTGCGGTCGCAATTCAGAATTCACATCATTTTGCAGCACTTTGGCCTGAAGTTGAAAAAATGAGTG
AAGCGGGCTTAATTGGCCTTACTACTGTTTCTTATCTTCCATGGGTTGCACCAGCTGGTGGCAAAACGCCGATTTTTGGA
ACCAACCCGATGGCCTTTTCGTGGCCTCGTGCCGGTAAAAATCCGGTTGTGATCGATATGGCAACGTCGTCAATGGCTAT
GGGTGAAGTCATGATAGCCGCCCGAGATGGCTATGAAGTGCCACTGGGCACAGGATTATCTGAATCAGGTGAATTAACAA
CTGATGCCGCCGAAATTGTGAAAGGCGTTCTATTACCTTTTGGTGGACACAAAGGGTCTGCATTAGCATTAATGGTGGAA
TTACTCTCTGGTCCGCTAGTAGGGGAAACCTTTTCCTATGAAACTCAGGAACGTGACAAGGCAGAAGAAGGACCGGCAAG
AGGAGGTCAATTTATTCTAGCCATTTCACCAGATATTCTATCAGGAAAAAATACCAGCGAACAAACGGATCGTTTTTTTG
AAAAGTATGATGCAATAGAAGGTGCACGGACCCCCGGTGCCAGACGGCATAAAAATAGAGAAAATAGCGGTCCACGGTCA
GTTAACGCAGATCTGGTAAAGACTATTGAGCAGCTTCGAACGGATGGTTTAATAACCTAA

Upstream 100 bases:

>100_bases
ACAAGATAAAGGTAATAACTAACATGAAAAATCTTAATTTGTTCAACCCGTTTTTTGATACGTATAGTATCTTTTTACAT
TCAGCAATCGAGTTTACCTC

Downstream 100 bases:

>100_bases
TATTTGTTTAATAAAAGTGTTTAGACTTGGTTTTTTTGCTGGTTTCTGCGTTGAATTTACTTGCAGGTAATAAATAATGG
CCAGACCAAGTAAAGAAATG

Product: malate/L-lactate dehydrogenase

Products: oxaloacetate; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSHLTINLTLEEIYDLAKTALLSQGANEENAAAIANTVTIAERDGAISHGLFRIPGYIVGLQSKKVVGTATPEIEEVTPI
IFRCDAKNGYAPLTHEHCLPPLIDAAKKFGLAAVAIQNSHHFAALWPEVEKMSEAGLIGLTTVSYLPWVAPAGGKTPIFG
TNPMAFSWPRAGKNPVVIDMATSSMAMGEVMIAARDGYEVPLGTGLSESGELTTDAAEIVKGVLLPFGGHKGSALALMVE
LLSGPLVGETFSYETQERDKAEEGPARGGQFILAISPDILSGKNTSEQTDRFFEKYDAIEGARTPGARRHKNRENSGPRS
VNADLVKTIEQLRTDGLIT

Sequences:

>Translated_339_residues
MSHLTINLTLEEIYDLAKTALLSQGANEENAAAIANTVTIAERDGAISHGLFRIPGYIVGLQSKKVVGTATPEIEEVTPI
IFRCDAKNGYAPLTHEHCLPPLIDAAKKFGLAAVAIQNSHHFAALWPEVEKMSEAGLIGLTTVSYLPWVAPAGGKTPIFG
TNPMAFSWPRAGKNPVVIDMATSSMAMGEVMIAARDGYEVPLGTGLSESGELTTDAAEIVKGVLLPFGGHKGSALALMVE
LLSGPLVGETFSYETQERDKAEEGPARGGQFILAISPDILSGKNTSEQTDRFFEKYDAIEGARTPGARRHKNRENSGPRS
VNADLVKTIEQLRTDGLIT
>Mature_338_residues
SHLTINLTLEEIYDLAKTALLSQGANEENAAAIANTVTIAERDGAISHGLFRIPGYIVGLQSKKVVGTATPEIEEVTPII
FRCDAKNGYAPLTHEHCLPPLIDAAKKFGLAAVAIQNSHHFAALWPEVEKMSEAGLIGLTTVSYLPWVAPAGGKTPIFGT
NPMAFSWPRAGKNPVVIDMATSSMAMGEVMIAARDGYEVPLGTGLSESGELTTDAAEIVKGVLLPFGGHKGSALALMVEL
LSGPLVGETFSYETQERDKAEEGPARGGQFILAISPDILSGKNTSEQTDRFFEKYDAIEGARTPGARRHKNRENSGPRSV
NADLVKTIEQLRTDGLIT

Specific function: Unknown

COG id: COG2055

COG function: function code C; Malate/L-lactate dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LDH2/MDH2 oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787020, Length=294, Percent_Identity=28.5714285714286, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786727, Length=283, Percent_Identity=27.9151943462898, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790000, Length=310, Percent_Identity=24.8387096774194, Blast_Score=96, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17507179, Length=284, Percent_Identity=26.4084507042254, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17536633, Length=279, Percent_Identity=27.9569892473118, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24667904, Length=263, Percent_Identity=30.7984790874525, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI45553211, Length=263, Percent_Identity=30.7984790874525, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24667912, Length=263, Percent_Identity=30.7984790874525, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24667908, Length=263, Percent_Identity=30.7984790874525, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24648360, Length=257, Percent_Identity=27.6264591439689, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24658010, Length=313, Percent_Identity=24.9201277955272, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003767 [H]

Pfam domain/function: PF02615 Ldh_2 [H]

EC number: 1.1.1.37

Molecular weight: Translated: 36167; Mature: 36035

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHLTINLTLEEIYDLAKTALLSQGANEENAAAIANTVTIAERDGAISHGLFRIPGYIVG
CCEEEEEEEHHHHHHHHHHHHHHCCCCCCCHHHHHEEEEEEECCCCHHCCEEECCCEEEE
LQSKKVVGTATPEIEEVTPIIFRCDAKNGYAPLTHEHCLPPLIDAAKKFGLAAVAIQNSH
ECCCCEEECCCCCHHHCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCEEEEEEECCC
HFAALWPEVEKMSEAGLIGLTTVSYLPWVAPAGGKTPIFGTNPMAFSWPRAGKNPVVIDM
CEEEECHHHHHHHHCCEEEEHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEE
ATSSMAMGEVMIAARDGYEVPLGTGLSESGELTTDAAEIVKGVLLPFGGHKGSALALMVE
CCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHH
LLSGPLVGETFSYETQERDKAEEGPARGGQFILAISPDILSGKNTSEQTDRFFEKYDAIE
HHCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCHHCCCCCCHHHHHHHHHHHHHHC
GARTPGARRHKNRENSGPRSVNADLVKTIEQLRTDGLIT
CCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SHLTINLTLEEIYDLAKTALLSQGANEENAAAIANTVTIAERDGAISHGLFRIPGYIVG
CEEEEEEEHHHHHHHHHHHHHHCCCCCCCHHHHHEEEEEEECCCCHHCCEEECCCEEEE
LQSKKVVGTATPEIEEVTPIIFRCDAKNGYAPLTHEHCLPPLIDAAKKFGLAAVAIQNSH
ECCCCEEECCCCCHHHCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCEEEEEEECCC
HFAALWPEVEKMSEAGLIGLTTVSYLPWVAPAGGKTPIFGTNPMAFSWPRAGKNPVVIDM
CEEEECHHHHHHHHCCEEEEHHHHHCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEEEE
ATSSMAMGEVMIAARDGYEVPLGTGLSESGELTTDAAEIVKGVLLPFGGHKGSALALMVE
CCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHH
LLSGPLVGETFSYETQERDKAEEGPARGGQFILAISPDILSGKNTSEQTDRFFEKYDAIE
HHCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCHHCCCCCCHHHHHHHHHHHHHHC
GARTPGARRHKNRENSGPRSVNADLVKTIEQLRTDGLIT
CCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-malate; NAD+

Specific reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]