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The map label for this gene is galM [H]

Identifier: 119945701

GI number: 119945701

Start: 2456322

End: 2457395

Strand: Direct

Name: galM [H]

Synonym: Ping_2018

Alternate gene names: 119945701

Gene position: 2456322-2457395 (Clockwise)

Preceding gene: 119945700

Following gene: 119945702

Centisome position: 53.87

GC content: 45.62

Gene sequence:

>1074_bases
ATGACCCTAAGTCGAGCAGAACAGTTACAGAAAAGCATGAGTATTGATCCCGCTTTTGATGGTCAACCCGCTAAAATTTT
TGTTTTAAAAAACAGGCTGGGTATGTGTATCACACTGATGGATATTGGTGCGACTTGGTTAAGCTGTGAAATTCCTGTTG
GCGATCAAATGCGCGACGTCATTCTTGGCGTCACGACTATGAATGATCATTTACGTCAGAAAGCTTATCTTGGCGCAACG
ATTGGCCGCTTTGCAAACCGACTTAGCGGCGGACAATTTAAGATTGCCGGGCAACATTATCAAGTTGATAAAAATCAAGG
GAATAATACCCTGCACGGTGGCGTGACAGGTTTTGATAAGTGCCGCTGGCACGCACAGCAGCTCAATAATCAGTGCGTTA
CTTTTACACTCTTATCCAAAGATGGCGACCAGGGTTTCCCAGGCAATTTAGACGTTAAAGTCACCTACCACTTAAGCGAT
GACAATGAACTGTCCATTGATTATTGGGCAGTGACGGATAAAGCGTGTCCCGTGAGCCTGACCAATCATGCTTATTTTAA
TTTGATGGGCGAGTCCGGGCAATGCTGTTTACAGCATCAGTTGTTTATTGCCGCCGAACACTATCTGCCGGTGAATAATA
CGGGCATTCCTATCGGGCATATAAAACCTGTTGCGGGCAGTCGTTTTGATTTTAGCGCGCTGAAAGAAATCAGTCAGGAC
TTCTTAAGTTGCCAGGATCAGAAGATAGTCGGCGGTTATGATCATTCATTTTTAATCAACAAGGCGCATCAGGATGGCAG
CAAAGTGGCGGCTAAATGTGTTTCACCGGATAAAAAAGTGACCCTTGAAATAAAAACCACGCAACCTGCTCTGCAGCTTT
ATACGGGAAATTATTTAGGCGGGACCCCGAACCGTTCTGGGGGGACCTATAAAAACCGGTCAGCATTGGCGCTGGAAACG
CAATTTTTACCCGACGCACCCAATCACCCTGAATGGGATCAGCCCAGCTCAATATTATTGCCTGGTGAGGTATACGCCCA
TCAAACATCTTATCGCTTTACTGTTGCCGATTAA

Upstream 100 bases:

>100_bases
GTTTGCAATGCAAGTGTGGGCGCGGGCATTGTCTTAGAAAAATGACAAATGAAGAGTGAAAAGTAATTTAACAAAAAAAG
TAATATGACAGAGAAACAAT

Downstream 100 bases:

>100_bases
CGAGTATCTCGTTGAGGTATAAAGAACATATTGAATTAATGCCGTGCGGTTAAGCCATTTCAGGCTTATGTCTCAACGGA
TATCTTAATAGTATATAAAG

Product: galactose mutarotase

Products: NA

Alternate protein names: Galactose mutarotase; Type-1 mutarotase [H]

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MTLSRAEQLQKSMSIDPAFDGQPAKIFVLKNRLGMCITLMDIGATWLSCEIPVGDQMRDVILGVTTMNDHLRQKAYLGAT
IGRFANRLSGGQFKIAGQHYQVDKNQGNNTLHGGVTGFDKCRWHAQQLNNQCVTFTLLSKDGDQGFPGNLDVKVTYHLSD
DNELSIDYWAVTDKACPVSLTNHAYFNLMGESGQCCLQHQLFIAAEHYLPVNNTGIPIGHIKPVAGSRFDFSALKEISQD
FLSCQDQKIVGGYDHSFLINKAHQDGSKVAAKCVSPDKKVTLEIKTTQPALQLYTGNYLGGTPNRSGGTYKNRSALALET
QFLPDAPNHPEWDQPSSILLPGEVYAHQTSYRFTVAD

Sequences:

>Translated_357_residues
MTLSRAEQLQKSMSIDPAFDGQPAKIFVLKNRLGMCITLMDIGATWLSCEIPVGDQMRDVILGVTTMNDHLRQKAYLGAT
IGRFANRLSGGQFKIAGQHYQVDKNQGNNTLHGGVTGFDKCRWHAQQLNNQCVTFTLLSKDGDQGFPGNLDVKVTYHLSD
DNELSIDYWAVTDKACPVSLTNHAYFNLMGESGQCCLQHQLFIAAEHYLPVNNTGIPIGHIKPVAGSRFDFSALKEISQD
FLSCQDQKIVGGYDHSFLINKAHQDGSKVAAKCVSPDKKVTLEIKTTQPALQLYTGNYLGGTPNRSGGTYKNRSALALET
QFLPDAPNHPEWDQPSSILLPGEVYAHQTSYRFTVAD
>Mature_356_residues
TLSRAEQLQKSMSIDPAFDGQPAKIFVLKNRLGMCITLMDIGATWLSCEIPVGDQMRDVILGVTTMNDHLRQKAYLGATI
GRFANRLSGGQFKIAGQHYQVDKNQGNNTLHGGVTGFDKCRWHAQQLNNQCVTFTLLSKDGDQGFPGNLDVKVTYHLSDD
NELSIDYWAVTDKACPVSLTNHAYFNLMGESGQCCLQHQLFIAAEHYLPVNNTGIPIGHIKPVAGSRFDFSALKEISQDF
LSCQDQKIVGGYDHSFLINKAHQDGSKVAAKCVSPDKKVTLEIKTTQPALQLYTGNYLGGTPNRSGGTYKNRSALALETQ
FLPDAPNHPEWDQPSSILLPGEVYAHQTSYRFTVAD

Specific function: Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose [H]

COG id: COG2017

COG function: function code G; Galactose mutarotase and related enzymes

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldose epimerase family [H]

Homologues:

Organism=Homo sapiens, GI20270355, Length=341, Percent_Identity=39.0029325513196, Blast_Score=225, Evalue=5e-59,
Organism=Escherichia coli, GI1786971, Length=337, Percent_Identity=50.4451038575668, Blast_Score=339, Evalue=2e-94,
Organism=Caenorhabditis elegans, GI17557428, Length=328, Percent_Identity=30.1829268292683, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI115533334, Length=328, Percent_Identity=30.1829268292683, Blast_Score=159, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6319493, Length=329, Percent_Identity=28.2674772036474, Blast_Score=119, Evalue=8e-28,
Organism=Saccharomyces cerevisiae, GI6322004, Length=341, Percent_Identity=30.791788856305, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6324399, Length=340, Percent_Identity=26.7647058823529, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24659048, Length=344, Percent_Identity=35.7558139534884, Blast_Score=205, Evalue=4e-53,
Organism=Drosophila melanogaster, GI24668278, Length=366, Percent_Identity=34.1530054644809, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24583720, Length=360, Percent_Identity=33.3333333333333, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24668282, Length=342, Percent_Identity=32.1637426900585, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24641876, Length=351, Percent_Identity=29.3447293447293, Blast_Score=148, Evalue=6e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018052
- InterPro:   IPR013458
- InterPro:   IPR008183
- InterPro:   IPR015443
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.3 [H]

Molecular weight: Translated: 39373; Mature: 39242

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS00545 ALDOSE_1_EPIMERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSRAEQLQKSMSIDPAFDGQPAKIFVLKNRLGMCITLMDIGATWLSCEIPVGDQMRDV
CCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCEEEEEECCCCCCCCEE
ILGVTTMNDHLRQKAYLGATIGRFANRLSGGQFKIAGQHYQVDKNQGNNTLHGGVTGFDK
EEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECCCCCCEEECCCCCHHH
CRWHAQQLNNQCVTFTLLSKDGDQGFPGNLDVKVTYHLSDDNELSIDYWAVTDKACPVSL
HHHHHHHHCCCEEEEEEEECCCCCCCCCCEEEEEEEEECCCCEEEEEEEEEECCCCCEEE
TNHAYFNLMGESGQCCLQHQLFIAAEHYLPVNNTGIPIGHIKPVAGSRFDFSALKEISQD
CCCEEEEEECCCCCEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
FLSCQDQKIVGGYDHSFLINKAHQDGSKVAAKCVSPDKKVTLEIKTTQPALQLYTGNYLG
HHCCCCCEEECCCCCEEEEECCCCCCHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCC
GTPNRSGGTYKNRSALALETQFLPDAPNHPEWDQPSSILLPGEVYAHQTSYRFTVAD
CCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEECCHHEEECCEEEEEECC
>Mature Secondary Structure 
TLSRAEQLQKSMSIDPAFDGQPAKIFVLKNRLGMCITLMDIGATWLSCEIPVGDQMRDV
CCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCEEEEEEECCCEEEEEECCCCCCCCEE
ILGVTTMNDHLRQKAYLGATIGRFANRLSGGQFKIAGQHYQVDKNQGNNTLHGGVTGFDK
EEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECCCCCCEEECCCCCHHH
CRWHAQQLNNQCVTFTLLSKDGDQGFPGNLDVKVTYHLSDDNELSIDYWAVTDKACPVSL
HHHHHHHHCCCEEEEEEEECCCCCCCCCCEEEEEEEEECCCCEEEEEEEEEECCCCCEEE
TNHAYFNLMGESGQCCLQHQLFIAAEHYLPVNNTGIPIGHIKPVAGSRFDFSALKEISQD
CCCEEEEEECCCCCEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
FLSCQDQKIVGGYDHSFLINKAHQDGSKVAAKCVSPDKKVTLEIKTTQPALQLYTGNYLG
HHCCCCCEEECCCCCEEEEECCCCCCHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCC
GTPNRSGGTYKNRSALALETQFLPDAPNHPEWDQPSSILLPGEVYAHQTSYRFTVAD
CCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEECCHHEEECCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7966338; 8905232; 9278503 [H]