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The map label for this gene is galE [H]

Identifier: 119945698

GI number: 119945698

Start: 2452892

End: 2453911

Strand: Direct

Name: galE [H]

Synonym: Ping_2015

Alternate gene names: 119945698

Gene position: 2452892-2453911 (Clockwise)

Preceding gene: 119945697

Following gene: 119945699

Centisome position: 53.8

GC content: 46.76

Gene sequence:

>1020_bases
ATGAAAGTATTAGTGACAGGGGGAATGGGTTACATAGGGAGCTTGACCTGCATACAAATGATTGAAGCCGGTATCGAGCC
TATTATTGTCGATAATTTAAGCAACAGTAAATTGACTGTATTAGATCGTATTGAAGCGTTAACGCAGATTCGCCCTCTTT
TTTACCCAGGTGATGTTCGTGATCAGCATCTATTAGATCGTATTTTCAGCGAACACGATGTTGACTCGGTTATTCACTTT
GCCGGGCTCAAATCCGTCGGTGAATCGGTACAGAAACCACTCGAGTACTATGATAACAATGTGAATGGATCGCTGGTGCT
GGCTGGTGCGATGCGTAAAGCCTGTGTGAAAAGTTTAGTCTTTAGCTCATCAGCAACCGTTTATGGCGATCCGGCGGTCG
TGCCGATCACTGAAAGCTCACCAACGGGTGCGACCACAAATCCCTACGGCCGCAGTAAATATATTGTTGAACAGTGCCTG
TCTGACTTGTTTGCCGCAGAGCCCGATTGGAGCATTACCTTATTGCGTTATTTTAATCCTGTCGGCGCCCACCCATCGGG
CACTATGGGTGAAGATCCAGAAGGGATTCCAAATAACTTAATGCCCTTTATTGCACAAGTTGCCGTTGGACGTCGTAAAT
CCTTAGCCGTCTTTGGTGATGATTACCCAACAGCAGATGGTACGGGTGTACGCGATTATATCCACGTCATGGATCTGGCA
GACGGACATATTGCAGCACTTAAAGCCGTGGGCAAAAAAGCAGGCTTACATATTTACAATTTAGGCACAGGCAAAGGCAG
CAGTGTTCTAGAAATGATCGATGCCTTTTCTAAGGCCTGCGGTAAACCTGTCGCTTATAATATTTTCCCGCGACGCGCCG
GTGATATTGCGCAGTGCTGTGCTGATCCCCAAAAAGCACAAAAAGAGCTGGGCTGGAAGGCAAACCGCACAATCATGGAG
ATGACCAAAGATACCTGGCACTGGCAATCGAAGAATCCACAGGGTTACTCAAAAGCTTAA

Upstream 100 bases:

>100_bases
TTAATATGCAAGGAATAGTCACCACCCTTATGGTCAGTAAACGCAATAACAGCGGTTTTCCTGCCGTATTTATAACCACC
CACATTTGGGAGAATGTAGT

Downstream 100 bases:

>100_bases
CCCTTACTGGCCATTATTTTTACCTGCTATAAATATTCCCCACCCGCAATATTAGCGAGTGGTGCAGCATACAGAAGAGG
ACACTATGACAACCATCGCT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MKVLVTGGMGYIGSLTCIQMIEAGIEPIIVDNLSNSKLTVLDRIEALTQIRPLFYPGDVRDQHLLDRIFSEHDVDSVIHF
AGLKSVGESVQKPLEYYDNNVNGSLVLAGAMRKACVKSLVFSSSATVYGDPAVVPITESSPTGATTNPYGRSKYIVEQCL
SDLFAAEPDWSITLLRYFNPVGAHPSGTMGEDPEGIPNNLMPFIAQVAVGRRKSLAVFGDDYPTADGTGVRDYIHVMDLA
DGHIAALKAVGKKAGLHIYNLGTGKGSSVLEMIDAFSKACGKPVAYNIFPRRAGDIAQCCADPQKAQKELGWKANRTIME
MTKDTWHWQSKNPQGYSKA

Sequences:

>Translated_339_residues
MKVLVTGGMGYIGSLTCIQMIEAGIEPIIVDNLSNSKLTVLDRIEALTQIRPLFYPGDVRDQHLLDRIFSEHDVDSVIHF
AGLKSVGESVQKPLEYYDNNVNGSLVLAGAMRKACVKSLVFSSSATVYGDPAVVPITESSPTGATTNPYGRSKYIVEQCL
SDLFAAEPDWSITLLRYFNPVGAHPSGTMGEDPEGIPNNLMPFIAQVAVGRRKSLAVFGDDYPTADGTGVRDYIHVMDLA
DGHIAALKAVGKKAGLHIYNLGTGKGSSVLEMIDAFSKACGKPVAYNIFPRRAGDIAQCCADPQKAQKELGWKANRTIME
MTKDTWHWQSKNPQGYSKA
>Mature_339_residues
MKVLVTGGMGYIGSLTCIQMIEAGIEPIIVDNLSNSKLTVLDRIEALTQIRPLFYPGDVRDQHLLDRIFSEHDVDSVIHF
AGLKSVGESVQKPLEYYDNNVNGSLVLAGAMRKACVKSLVFSSSATVYGDPAVVPITESSPTGATTNPYGRSKYIVEQCL
SDLFAAEPDWSITLLRYFNPVGAHPSGTMGEDPEGIPNNLMPFIAQVAVGRRKSLAVFGDDYPTADGTGVRDYIHVMDLA
DGHIAALKAVGKKAGLHIYNLGTGKGSSVLEMIDAFSKACGKPVAYNIFPRRAGDIAQCCADPQKAQKELGWKANRTIME
MTKDTWHWQSKNPQGYSKA

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=341, Percent_Identity=54.2521994134897, Blast_Score=390, Evalue=1e-109,
Organism=Homo sapiens, GI56118217, Length=341, Percent_Identity=54.2521994134897, Blast_Score=390, Evalue=1e-109,
Organism=Homo sapiens, GI189083684, Length=341, Percent_Identity=54.2521994134897, Blast_Score=390, Evalue=1e-109,
Organism=Homo sapiens, GI7657641, Length=347, Percent_Identity=25.9365994236311, Blast_Score=96, Evalue=7e-20,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=65.4761904761905, Blast_Score=472, Evalue=1e-134,
Organism=Escherichia coli, GI1788353, Length=363, Percent_Identity=28.6501377410468, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI48994969, Length=365, Percent_Identity=25.2054794520548, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71982035, Length=347, Percent_Identity=50.4322766570605, Blast_Score=349, Evalue=1e-96,
Organism=Caenorhabditis elegans, GI71982038, Length=349, Percent_Identity=50.1432664756447, Blast_Score=348, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI17568069, Length=343, Percent_Identity=25.0728862973761, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=343, Percent_Identity=52.1865889212828, Blast_Score=360, Evalue=1e-100,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=54.8104956268222, Blast_Score=380, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36774; Mature: 36774

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVTGGMGYIGSLTCIQMIEAGIEPIIVDNLSNSKLTVLDRIEALTQIRPLFYPGDVR
CEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEHHHHHHHHHHHHCCCCCCCCCC
DQHLLDRIFSEHDVDSVIHFAGLKSVGESVQKPLEYYDNNVNGSLVLAGAMRKACVKSLV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHH
FSSSATVYGDPAVVPITESSPTGATTNPYGRSKYIVEQCLSDLFAAEPDWSITLLRYFNP
HCCCCEEECCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEHHHHCCC
VGAHPSGTMGEDPEGIPNNLMPFIAQVAVGRRKSLAVFGDDYPTADGTGVRDYIHVMDLA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHCC
DGHIAALKAVGKKAGLHIYNLGTGKGSSVLEMIDAFSKACGKPVAYNIFPRRAGDIAQCC
CCHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHH
ADPQKAQKELGWKANRTIMEMTKDTWHWQSKNPQGYSKA
CCHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MKVLVTGGMGYIGSLTCIQMIEAGIEPIIVDNLSNSKLTVLDRIEALTQIRPLFYPGDVR
CEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEHHHHHHHHHHHHCCCCCCCCCC
DQHLLDRIFSEHDVDSVIHFAGLKSVGESVQKPLEYYDNNVNGSLVLAGAMRKACVKSLV
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHH
FSSSATVYGDPAVVPITESSPTGATTNPYGRSKYIVEQCLSDLFAAEPDWSITLLRYFNP
HCCCCEEECCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEHHHHCCC
VGAHPSGTMGEDPEGIPNNLMPFIAQVAVGRRKSLAVFGDDYPTADGTGVRDYIHVMDLA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHCC
DGHIAALKAVGKKAGLHIYNLGTGKGSSVLEMIDAFSKACGKPVAYNIFPRRAGDIAQCC
CCHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHH
ADPQKAQKELGWKANRTIMEMTKDTWHWQSKNPQGYSKA
CCHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]