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The map label for this gene is ndh [H]

Identifier: 119945672

GI number: 119945672

Start: 2415454

End: 2416740

Strand: Reverse

Name: ndh [H]

Synonym: Ping_1985

Alternate gene names: 119945672

Gene position: 2416740-2415454 (Counterclockwise)

Preceding gene: 119945673

Following gene: 119945666

Centisome position: 53.0

GC content: 40.25

Gene sequence:

>1287_bases
ATGGACAAAATCGTGATCGTTGGAGGAGGGGCCGGAGGCCTTGAATTAGCGACGGAACTGGGTGATAAGCTTGGACGAAA
GAAAAAGGCGCATATTACGCTTGTTGATAAAAACAGCACACATTTGTGGAAACCTTTATTACATGAAGTTGCAGCCGGAT
CCCTTGATGATGGAATTGATGCCTTAAGTTATCGTGCGCATGCAAAAAATCATCATTTTAGTTTTCAACTTGGGGCATTG
TCGAATATTGAAAGAGAAAATAAAAAAATACAGATAGCTGAATTATTAGATAATGACGGTATAAAGATTTTACCTGAATG
TACCGTTAGTTATGACATTTTAGTGATCGCCCTTGGCAGTGTGAGTAATGATTTTAATACTAAAGGTGTGCGTGAGCATT
GCATCTTTCTGGATAGCCCGCAACAGGCAAAAAAATTCCATCACCGTATGTTGAATAAATATTTACAACTTGGCGTCCAC
CAAACTAAGAAAGTAAGTGTCGCTATTGTGGGGGCTGGGGCAACGGGCGTTGAATTGTCGGCTGAGCTTTATAATGCGTT
AGAACAAGTGACCAGATATGGTTTTGAAGATATTAAAACCACGGATCTCAACGTTAGTCTTGTTGAAGCGGGTGATAAAA
TTTTACCTGCACTGCCCGAGAGAATATCCAGTTCAGCACATCAGGAGCTTTTAAAACTGGGGGTTTCTGTTCGTACCAAT
ACCTTAGTTACCGAGGCGACTGCAGCAGGGTTGATGACTAAAGAAGGTGAATTAATAGAAGCTGATTTAATTGTTTGGGC
CGCAGGTATCAAAGCGCCTGATTTTATGAAGGAGATAGCAGGTTTAGAAACAAACAGGGTAAACCAACTGATTGTTAAAC
CAACATTGCAGACTACTTTAGATGATAGTATTTATGCAATAGGCGACTGTGCCAGCTGCGCTTTGCCTAATGGCGGTTTT
GTACCTCCTCGTGCTCAATCAGCCCATCAGATGGCATCTTTAGTGGCTAAAAATATCAGAGCGACACTTGATAATAAAGC
ATTATCTCCCTATAAATATACGGATTATGGCTCATTAGTTTCATTAAGTAATTACAGTGCTGTGGGCAGTTTAATGGGTA
ATTTAACCAAAGGTTCGATGAAGGTTGAAGGGACTGTGGCTCGTTTAGTGTATATTTCACTGTATCGTATGCACCAAGTT
GCGCTTCACGGATATGTTCGTACGGGATTAATTACCTTAGTCGAAAGCATTAATAAAATATTACGTCCTCGTTTAAAATT
ACACTAA

Upstream 100 bases:

>100_bases
GGGGCTAATTTAAAACCCCTTTTCATGAAGATCATGGCTATTGAGTAGTGTTTTAATGTAATAAAATTTAATAATTATTT
ACAAAAACTTGGAGTGAATT

Downstream 100 bases:

>100_bases
AAATATAATACAAAACGGAGGATTACATTTCCCGTTTAAACGACTTGGATCAGCCTATTCAAGTCGTTTGGGGTTAACTG
TTGCGCTTAAAACAGTCTTT

Product: fused respiratory FAD-dependent NADH dehydrogenase and cupric reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MDKIVIVGGGAGGLELATELGDKLGRKKKAHITLVDKNSTHLWKPLLHEVAAGSLDDGIDALSYRAHAKNHHFSFQLGAL
SNIERENKKIQIAELLDNDGIKILPECTVSYDILVIALGSVSNDFNTKGVREHCIFLDSPQQAKKFHHRMLNKYLQLGVH
QTKKVSVAIVGAGATGVELSAELYNALEQVTRYGFEDIKTTDLNVSLVEAGDKILPALPERISSSAHQELLKLGVSVRTN
TLVTEATAAGLMTKEGELIEADLIVWAAGIKAPDFMKEIAGLETNRVNQLIVKPTLQTTLDDSIYAIGDCASCALPNGGF
VPPRAQSAHQMASLVAKNIRATLDNKALSPYKYTDYGSLVSLSNYSAVGSLMGNLTKGSMKVEGTVARLVYISLYRMHQV
ALHGYVRTGLITLVESINKILRPRLKLH

Sequences:

>Translated_428_residues
MDKIVIVGGGAGGLELATELGDKLGRKKKAHITLVDKNSTHLWKPLLHEVAAGSLDDGIDALSYRAHAKNHHFSFQLGAL
SNIERENKKIQIAELLDNDGIKILPECTVSYDILVIALGSVSNDFNTKGVREHCIFLDSPQQAKKFHHRMLNKYLQLGVH
QTKKVSVAIVGAGATGVELSAELYNALEQVTRYGFEDIKTTDLNVSLVEAGDKILPALPERISSSAHQELLKLGVSVRTN
TLVTEATAAGLMTKEGELIEADLIVWAAGIKAPDFMKEIAGLETNRVNQLIVKPTLQTTLDDSIYAIGDCASCALPNGGF
VPPRAQSAHQMASLVAKNIRATLDNKALSPYKYTDYGSLVSLSNYSAVGSLMGNLTKGSMKVEGTVARLVYISLYRMHQV
ALHGYVRTGLITLVESINKILRPRLKLH
>Mature_428_residues
MDKIVIVGGGAGGLELATELGDKLGRKKKAHITLVDKNSTHLWKPLLHEVAAGSLDDGIDALSYRAHAKNHHFSFQLGAL
SNIERENKKIQIAELLDNDGIKILPECTVSYDILVIALGSVSNDFNTKGVREHCIFLDSPQQAKKFHHRMLNKYLQLGVH
QTKKVSVAIVGAGATGVELSAELYNALEQVTRYGFEDIKTTDLNVSLVEAGDKILPALPERISSSAHQELLKLGVSVRTN
TLVTEATAAGLMTKEGELIEADLIVWAAGIKAPDFMKEIAGLETNRVNQLIVKPTLQTTLDDSIYAIGDCASCALPNGGF
VPPRAQSAHQMASLVAKNIRATLDNKALSPYKYTDYGSLVSLSNYSAVGSLMGNLTKGSMKVEGTVARLVYISLYRMHQV
ALHGYVRTGLITLVESINKILRPRLKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=430, Percent_Identity=66.9767441860465, Blast_Score=588, Evalue=1e-169,
Organism=Saccharomyces cerevisiae, GI6320118, Length=439, Percent_Identity=24.6013667425968, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6323794, Length=358, Percent_Identity=25.6983240223464, Blast_Score=85, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323515, Length=443, Percent_Identity=24.1534988713318, Blast_Score=81, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 46467; Mature: 46467

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIVIVGGGAGGLELATELGDKLGRKKKAHITLVDKNSTHLWKPLLHEVAAGSLDDGID
CCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCHH
ALSYRAHAKNHHFSFQLGALSNIERENKKIQIAELLDNDGIKILPECTVSYDILVIALGS
HHHHHHHCCCCCEEEEECCHHCCHHCCCEEEEEHHHCCCCCEEEECCCCCEEEEEEEECC
VSNDFNTKGVREHCIFLDSPQQAKKFHHRMLNKYLQLGVHQTKKVSVAIVGAGATGVELS
CCCCCCCCCCHHHEEEECCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHH
AELYNALEQVTRYGFEDIKTTDLNVSLVEAGDKILPALPERISSSAHQELLKLGVSVRTN
HHHHHHHHHHHHCCCCCCEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEECC
TLVTEATAAGLMTKEGELIEADLIVWAAGIKAPDFMKEIAGLETNRVNQLIVKPTLQTTL
EEEEHHHHHCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHCCCCCCCCEEEECCCHHHHH
DDSIYAIGDCASCALPNGGFVPPRAQSAHQMASLVAKNIRATLDNKALSPYKYTDYGSLV
CCCEEEECCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCEE
SLSNYSAVGSLMGNLTKGSMKVEGTVARLVYISLYRMHQVALHGYVRTGLITLVESINKI
ECCCHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRPRLKLH
HCCHHCCC
>Mature Secondary Structure
MDKIVIVGGGAGGLELATELGDKLGRKKKAHITLVDKNSTHLWKPLLHEVAAGSLDDGID
CCEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCHH
ALSYRAHAKNHHFSFQLGALSNIERENKKIQIAELLDNDGIKILPECTVSYDILVIALGS
HHHHHHHCCCCCEEEEECCHHCCHHCCCEEEEEHHHCCCCCEEEECCCCCEEEEEEEECC
VSNDFNTKGVREHCIFLDSPQQAKKFHHRMLNKYLQLGVHQTKKVSVAIVGAGATGVELS
CCCCCCCCCCHHHEEEECCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHH
AELYNALEQVTRYGFEDIKTTDLNVSLVEAGDKILPALPERISSSAHQELLKLGVSVRTN
HHHHHHHHHHHHCCCCCCEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEECC
TLVTEATAAGLMTKEGELIEADLIVWAAGIKAPDFMKEIAGLETNRVNQLIVKPTLQTTL
EEEEHHHHHCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHCCCCCCCCEEEECCCHHHHH
DDSIYAIGDCASCALPNGGFVPPRAQSAHQMASLVAKNIRATLDNKALSPYKYTDYGSLV
CCCEEEECCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCEE
SLSNYSAVGSLMGNLTKGSMKVEGTVARLVYISLYRMHQVALHGYVRTGLITLVESINKI
ECCCHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRPRLKLH
HCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]