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The map label for this gene is fabA [H]

Identifier: 119945669

GI number: 119945669

Start: 2412279

End: 2412818

Strand: Direct

Name: fabA [H]

Synonym: Ping_1982

Alternate gene names: 119945669

Gene position: 2412279-2412818 (Clockwise)

Preceding gene: 119945668

Following gene: 119945670

Centisome position: 52.91

GC content: 41.3

Gene sequence:

>540_bases
ATGACTAAAATCCTATCCCAAAAAGAGTTGGGTAAAAACTCTTATACAAAAGAAGAATTAATCAAATGTGGTCAAGGTGA
GTTATTTGGAAAAGGAAATTGCCAACTGCCTGTAGATAAAATGCTGATGCTAGATCGGATCATCTCCATTACCGAGAACG
GCGGCGAATTCGGTAAAGGTGAATTGATTGCAGAATTAGATATAGATGAAGCATTATGGTTTTTTGAATGCCATTTCCCG
GGTGACCCTGTTATGCCCGGTTGTTTAGGCCTTGATGCCATGTGGCAATTAGTCGGCTTCTTCCTTGGTTGGAGTGGCGG
CCCCGGAAAAGGTCGTGCACTCGGTGTAGGTAATGTAAAATTTACTGGGCAAATTTTGCCCACCTCCAAAAAAGTGACCT
ACCGTATCACCCTCAAACGTTTAATTATGCGTAAACTTGTTATGGGTATTGCTGATGGTGTTGTTGAAGTGGATGGGAAA
GTTATTTATACGGCAGAAGATCTGAAAGTGGGTCTATTTGTTGATACAACCAGTTTCTAA

Upstream 100 bases:

>100_bases
TATTTATCTGTCATATAAAGTGTGCTCAAAATTTTCCAGGGTATTTCTATTTTTATGGTGAAATACCTCACCACTTGCAA
TGATGACAGATAAGTGAATT

Downstream 100 bases:

>100_bases
TTTCACTAAAACCTACTAAAATCTACTAAAGCACTGTATATGCCAATATCAGTGCTTTATTTTTATCTTCCCCTCCTAAA
ATTTACAGGTTGAAAATGAA

Product: 3-hydroxydecanoyl-(acyl carrier protein) dehydratase

Products: NA

Alternate protein names: Beta-hydroxydecanoyl thioester dehydrase [H]

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MTKILSQKELGKNSYTKEELIKCGQGELFGKGNCQLPVDKMLMLDRIISITENGGEFGKGELIAELDIDEALWFFECHFP
GDPVMPGCLGLDAMWQLVGFFLGWSGGPGKGRALGVGNVKFTGQILPTSKKVTYRITLKRLIMRKLVMGIADGVVEVDGK
VIYTAEDLKVGLFVDTTSF

Sequences:

>Translated_179_residues
MTKILSQKELGKNSYTKEELIKCGQGELFGKGNCQLPVDKMLMLDRIISITENGGEFGKGELIAELDIDEALWFFECHFP
GDPVMPGCLGLDAMWQLVGFFLGWSGGPGKGRALGVGNVKFTGQILPTSKKVTYRITLKRLIMRKLVMGIADGVVEVDGK
VIYTAEDLKVGLFVDTTSF
>Mature_178_residues
TKILSQKELGKNSYTKEELIKCGQGELFGKGNCQLPVDKMLMLDRIISITENGGEFGKGELIAELDIDEALWFFECHFPG
DPVMPGCLGLDAMWQLVGFFLGWSGGPGKGRALGVGNVKFTGQILPTSKKVTYRITLKRLIMRKLVMGIADGVVEVDGKV
IYTAEDLKVGLFVDTTSF

Specific function: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzed the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787187, Length=168, Percent_Identity=69.0476190476191, Blast_Score=245, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR010083
- InterPro:   IPR013114 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: =4.2.1.60 [H]

Molecular weight: Translated: 19627; Mature: 19496

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKILSQKELGKNSYTKEELIKCGQGELFGKGNCQLPVDKMLMLDRIISITENGGEFGKG
CCCCCCHHHCCCCCCCHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
ELIAELDIDEALWFFECHFPGDPVMPGCLGLDAMWQLVGFFLGWSGGPGKGRALGVGNVK
CEEEEECCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCEE
FTGQILPTSKKVTYRITLKRLIMRKLVMGIADGVVEVDGKVIYTAEDLKVGLFVDTTSF
EEEEEECCCCEEEEEEHHHHHHHHHHHHHHHCCEEEECCEEEEEECCCEEEEEEEECCC
>Mature Secondary Structure 
TKILSQKELGKNSYTKEELIKCGQGELFGKGNCQLPVDKMLMLDRIISITENGGEFGKG
CCCCCHHHCCCCCCCHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
ELIAELDIDEALWFFECHFPGDPVMPGCLGLDAMWQLVGFFLGWSGGPGKGRALGVGNVK
CEEEEECCCCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEECCCEE
FTGQILPTSKKVTYRITLKRLIMRKLVMGIADGVVEVDGKVIYTAEDLKVGLFVDTTSF
EEEEEECCCCEEEEEEHHHHHHHHHHHHHHHCCEEEECCEEEEEECCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA