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The map label for this gene is asnC

Identifier: 119945617

GI number: 119945617

Start: 2352694

End: 2354094

Strand: Direct

Name: asnC

Synonym: Ping_1926

Alternate gene names: 119945617

Gene position: 2352694-2354094 (Clockwise)

Preceding gene: 119945616

Following gene: 119945618

Centisome position: 51.6

GC content: 43.75

Gene sequence:

>1401_bases
ATGTCAAAAACAGCGATTGTTGAAATATTCAACAGTAAATTCCCGATCGGTACAGAAGTAACAGTTCAAGGCTGGATTCG
TACTCGTCGCGATTCAAAAGCCGGTATTTCTTTTTTAGCTATTTATGATGGTTCATGTTTTGACCCTATTCAGGCTGTTG
TTCCTGCCGCATTAGAAAATTACAGCGATGAAGTGCTCAATTTGACCGCAGGTTGTTCTGTGCAAGTCACGGGCGAGTTA
GTTGAAAGCCCGGGGAAAGGTCAACAATTTGAAATTCAGGCAACGCAGGTTGAGGTATTAGGTTTTGTTCAAGATCCAGA
TACCTATCCAATGTCGGCAAAACGTCATAGCATTGAATATATGCGCGAGCATGCACATCTGCGCGCACGTACTAATATGT
TTGGTGCGGTAACACGGGTTCGTAACTGCCTGTCACATGCGATGCACAACTTCTTTTATGAAAAAGGTTTTAACTGGATA
AGTACCCCCATCATTACCGGTAGTGATGCTGAAGGCGCTGGCGAAATGTTCCGCGTCAGCACGCTGGATTTAGAAAATTT
GCCGAGAAATGACACGGGTGCGATTGATTATAAAAAAGACTTTTTTGGTAAAGAAACGTTCTTAACGGTATCGGGTCAGC
TAAATGCAGAAACCTATGCCTGCGCCTTAAGCAAGGTATACACTTTTGGTCCAACTTTCCGGGCAGAAAATTCCCATACA
ACACGCCATCTGGCGGAGTTTTGGATGGTTGAACCTGAAATTGCCTTTGCAGATTTAGCCGATGCAGCACAACTCGCTGA
AGATATGCTTAAATATGTCTTTAATGCCGTATTAACTGAACGTGCCGATGACATGGCTTTCTTTGCACAACGTGTCGATA
AAGAAGCTATTACGCGTTTAGAAAAAATAGTCAGTTCAGAATTCGTGCGCATGGATTACACCGATGCGATTGAAATACTG
CAAAACTGCGGTAAAGAATTTGAATTCCCCGTTGCATGGGGTGTCGATTTACAATCTGAGCATGAACGTTACCTTGCTGA
AGTACATGTTGGTGCACCGGTTATTTTACAAAACTATCCGAAAGACATTAAAGCCTTCTACATGAAATTAAATGCAGATG
GTAAAACTGTTGCTGCAATGGATGTCTTAGCACCCGGGATTGGTGAAATCATTGGTGGCAGTCAGCGTGAAGAAGACTTA
GTCGCGCTGGATAAACGTTTTGACGAAATGGGCATCAACAAAGAAGATTATAGCTGGTATCGAGATCTGCGTAAATACGG
CACTGTGCCACATGCAGGTTTTGGTCTGGGTTTTGAACGCTTAGTGTCCTATGTGACCGGGGTGCAAAATATTCGTGATG
TGATCGCCTTCCCGCGTGCACCGGGCAGTGCAGATTTCTAA

Upstream 100 bases:

>100_bases
TAAGGATAGGCTTGTATCTAAGCCTAGCCTAGGTAATATATGCTCCTATTATTTTTAACGTTAAATCACTGCCAATGGTG
ATTATGGAGCACTAATTCTG

Downstream 100 bases:

>100_bases
ACTTAGCTCTTTATTTATAATAAAAAAAGCCAGCATTAATTGCTGGCTTTTTTTTGCTTAATTTATTTAATATAATAATA
AGCTAACTGTTTTTAGAAAT

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MSKTAIVEIFNSKFPIGTEVTVQGWIRTRRDSKAGISFLAIYDGSCFDPIQAVVPAALENYSDEVLNLTAGCSVQVTGEL
VESPGKGQQFEIQATQVEVLGFVQDPDTYPMSAKRHSIEYMREHAHLRARTNMFGAVTRVRNCLSHAMHNFFYEKGFNWI
STPIITGSDAEGAGEMFRVSTLDLENLPRNDTGAIDYKKDFFGKETFLTVSGQLNAETYACALSKVYTFGPTFRAENSHT
TRHLAEFWMVEPEIAFADLADAAQLAEDMLKYVFNAVLTERADDMAFFAQRVDKEAITRLEKIVSSEFVRMDYTDAIEIL
QNCGKEFEFPVAWGVDLQSEHERYLAEVHVGAPVILQNYPKDIKAFYMKLNADGKTVAAMDVLAPGIGEIIGGSQREEDL
VALDKRFDEMGINKEDYSWYRDLRKYGTVPHAGFGLGFERLVSYVTGVQNIRDVIAFPRAPGSADF

Sequences:

>Translated_466_residues
MSKTAIVEIFNSKFPIGTEVTVQGWIRTRRDSKAGISFLAIYDGSCFDPIQAVVPAALENYSDEVLNLTAGCSVQVTGEL
VESPGKGQQFEIQATQVEVLGFVQDPDTYPMSAKRHSIEYMREHAHLRARTNMFGAVTRVRNCLSHAMHNFFYEKGFNWI
STPIITGSDAEGAGEMFRVSTLDLENLPRNDTGAIDYKKDFFGKETFLTVSGQLNAETYACALSKVYTFGPTFRAENSHT
TRHLAEFWMVEPEIAFADLADAAQLAEDMLKYVFNAVLTERADDMAFFAQRVDKEAITRLEKIVSSEFVRMDYTDAIEIL
QNCGKEFEFPVAWGVDLQSEHERYLAEVHVGAPVILQNYPKDIKAFYMKLNADGKTVAAMDVLAPGIGEIIGGSQREEDL
VALDKRFDEMGINKEDYSWYRDLRKYGTVPHAGFGLGFERLVSYVTGVQNIRDVIAFPRAPGSADF
>Mature_465_residues
SKTAIVEIFNSKFPIGTEVTVQGWIRTRRDSKAGISFLAIYDGSCFDPIQAVVPAALENYSDEVLNLTAGCSVQVTGELV
ESPGKGQQFEIQATQVEVLGFVQDPDTYPMSAKRHSIEYMREHAHLRARTNMFGAVTRVRNCLSHAMHNFFYEKGFNWIS
TPIITGSDAEGAGEMFRVSTLDLENLPRNDTGAIDYKKDFFGKETFLTVSGQLNAETYACALSKVYTFGPTFRAENSHTT
RHLAEFWMVEPEIAFADLADAAQLAEDMLKYVFNAVLTERADDMAFFAQRVDKEAITRLEKIVSSEFVRMDYTDAIEILQ
NCGKEFEFPVAWGVDLQSEHERYLAEVHVGAPVILQNYPKDIKAFYMKLNADGKTVAAMDVLAPGIGEIIGGSQREEDLV
ALDKRFDEMGINKEDYSWYRDLRKYGTVPHAGFGLGFERLVSYVTGVQNIRDVIAFPRAPGSADF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI226491502, Length=467, Percent_Identity=41.3276231263383, Blast_Score=373, Evalue=1e-103,
Organism=Homo sapiens, GI4758762, Length=454, Percent_Identity=29.0748898678414, Blast_Score=195, Evalue=6e-50,
Organism=Homo sapiens, GI45439306, Length=349, Percent_Identity=29.2263610315186, Blast_Score=125, Evalue=7e-29,
Organism=Escherichia coli, GI1787161, Length=466, Percent_Identity=72.7467811158798, Blast_Score=743, Evalue=0.0,
Organism=Escherichia coli, GI1788173, Length=109, Percent_Identity=38.5321100917431, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790571, Length=467, Percent_Identity=22.2698072805139, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71984122, Length=474, Percent_Identity=30.5907172995781, Blast_Score=202, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI17556372, Length=427, Percent_Identity=30.6791569086651, Blast_Score=195, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17551876, Length=339, Percent_Identity=28.023598820059, Blast_Score=111, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319872, Length=473, Percent_Identity=34.6723044397463, Blast_Score=285, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6321807, Length=467, Percent_Identity=31.4775160599572, Blast_Score=204, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6323011, Length=477, Percent_Identity=26.4150943396226, Blast_Score=130, Evalue=6e-31,
Organism=Drosophila melanogaster, GI19922416, Length=462, Percent_Identity=38.0952380952381, Blast_Score=298, Evalue=4e-81,
Organism=Drosophila melanogaster, GI19921528, Length=449, Percent_Identity=30.0668151447661, Blast_Score=182, Evalue=5e-46,
Organism=Drosophila melanogaster, GI17136276, Length=343, Percent_Identity=28.2798833819242, Blast_Score=110, Evalue=3e-24,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYN_PSYIN (A1SW33)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_943297.1
- ProteinModelPortal:   A1SW33
- SMR:   A1SW33
- STRING:   A1SW33
- GeneID:   4626940
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_1926
- eggNOG:   COG0017
- HOGENOM:   HBG745843
- OMA:   EPEMAFC
- PhylomeDB:   A1SW33
- ProtClustDB:   PRK03932
- BioCyc:   PING357804:PING_1926-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00534
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00457

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.22

Molecular weight: Translated: 52189; Mature: 52058

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTAIVEIFNSKFPIGTEVTVQGWIRTRRDSKAGISFLAIYDGSCFDPIQAVVPAALEN
CCCCEEEEECCCCCCCCCCEEEHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHC
YSDEVLNLTAGCSVQVTGELVESPGKGQQFEIQATQVEVLGFVQDPDTYPMSAKRHSIEY
CCHHHHEEECCCEEEEEHHHHCCCCCCCEEEEEEEEEEEEEEEECCCCCCCCHHHHHHHH
MREHAHLRARTNMFGAVTRVRNCLSHAMHNFFYEKGFNWISTPIITGSDAEGAGEMFRVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEECCCCCCCCCEEEEE
TLDLENLPRNDTGAIDYKKDFFGKETFLTVSGQLNAETYACALSKVYTFGPTFRAENSHT
EECHHHCCCCCCCCCCCHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCH
TRHLAEFWMVEPEIAFADLADAAQLAEDMLKYVFNAVLTERADDMAFFAQRVDKEAITRL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHH
EKIVSSEFVRMDYTDAIEILQNCGKEFEFPVAWGVDLQSEHERYLAEVHVGAPVILQNYP
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCHHHHCCC
KDIKAFYMKLNADGKTVAAMDVLAPGIGEIIGGSQREEDLVALDKRFDEMGINKEDYSWY
HHHEEEEEEECCCCCEEEHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
RDLRKYGTVPHAGFGLGFERLVSYVTGVQNIRDVIAFPRAPGSADF
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SKTAIVEIFNSKFPIGTEVTVQGWIRTRRDSKAGISFLAIYDGSCFDPIQAVVPAALEN
CCCEEEEECCCCCCCCCCEEEHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHC
YSDEVLNLTAGCSVQVTGELVESPGKGQQFEIQATQVEVLGFVQDPDTYPMSAKRHSIEY
CCHHHHEEECCCEEEEEHHHHCCCCCCCEEEEEEEEEEEEEEEECCCCCCCCHHHHHHHH
MREHAHLRARTNMFGAVTRVRNCLSHAMHNFFYEKGFNWISTPIITGSDAEGAGEMFRVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEECCCCCCCCCEEEEE
TLDLENLPRNDTGAIDYKKDFFGKETFLTVSGQLNAETYACALSKVYTFGPTFRAENSHT
EECHHHCCCCCCCCCCCHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCH
TRHLAEFWMVEPEIAFADLADAAQLAEDMLKYVFNAVLTERADDMAFFAQRVDKEAITRL
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHH
EKIVSSEFVRMDYTDAIEILQNCGKEFEFPVAWGVDLQSEHERYLAEVHVGAPVILQNYP
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHCCCCHHHHCCC
KDIKAFYMKLNADGKTVAAMDVLAPGIGEIIGGSQREEDLVALDKRFDEMGINKEDYSWY
HHHEEEEEEECCCCCEEEHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHH
RDLRKYGTVPHAGFGLGFERLVSYVTGVQNIRDVIAFPRAPGSADF
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA