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The map label for this gene is atoS [H]

Identifier: 119945449

GI number: 119945449

Start: 2128141

End: 2129661

Strand: Direct

Name: atoS [H]

Synonym: Ping_1746

Alternate gene names: 119945449

Gene position: 2128141-2129661 (Clockwise)

Preceding gene: 119945448

Following gene: 119945450

Centisome position: 46.67

GC content: 44.77

Gene sequence:

>1521_bases
ATGACTGATCATGATAATTTAAACCTCCATGCGACCAATGGATCCGTTTTGAAACAGTCTGTGTCGGAGAAAATGGGAGA
CAATCTACAATACCAGCAGCTCTACGATATGCTGCTTAATGCCACTCCTTCCTCCGTATTATTGATTGACAGCAATTTCC
GTATTACCTCGGCTAATCGTAATTTCCTCACTCGAAGTCAGCGCACTCTTTCAGCTACAATAGGTTGCCGGCTTAGGGAA
GTCTTCCCGATAGTTATTCTAGAACGAATGGATATCAAGCAACAGATCCAAGAAGTGTTCAATACTCACAAAGCTTCCGT
AGGACAACGTATGACCTATCGGGCCCCCGGCGTGCCGTTTAAAACTTATTATTATCGTATTTTGCCTATAGAATCCAGCG
AGCAGTGTGAACAAGTCATGTTGCTGATGGAAGATATTACCGATCAGATCCGCCTCAGTGAAGATATGCGTCGTGTGGAA
AGTCACCTCGGTAGCATTGTGGAAAGCGCTAGCGACTTGATGCTGTCTTTAGATACTGAAGGGCGTATCTTAACTTGGAA
CTCGGCGGCAGAAAAACTCTCAGGATTTACGTTTCTAAAGGTTCAAGGAAAGTTCTTTTTCGAGTTTTTCAAAGCCTCTG
AGCATTTAGAAATCAAGACGTTTTTTATCAATATATGTATTAATGTTTGCTCCCTGAACGCCGAGTGGGAGTTGATCTCT
AAGAAAGGTATTGAAATCTCCGTTGCCTGGATTTTCTCGCCAATGAAAGATGACGATGCCAAAACCGTAGGCATTGTTGC
TGTCGGGCGGGATCTGACCGAACAACGCAAGTTAGAGGTCGAGTTGCGGCAGTCACAAAAACTAGCCGCACTCGGGGTAA
TGGCTGGCGGTATCGCCCACGAAATTCGTAACCCCCTTGCAGTTTGTTCCTCGGCGGCGCAATTTCTGATGGAAGAGGGG
CTTCCACTTGAATTCAGAACCGAATGTGCGAAGAAAATCCAAGTCAGTCTTGAGAAGGCTTCCTGCATCATTGAAAATCT
GTTGCGCTTTTCCAGACCTTCCTGTGAGCAAAATATGGTGCCGATGGATCTGGATACTGTGCTATGCGAAACGATTATGT
TAATCGCAAACCAAGCCAAGGTATATAAAATTGAAATAGTCTATCTACCTATTGGAAAATGCAGTTTGGTGTCTGGAATA
TTTACTCTGCTACAGCAAGTCTTTATGAATTTTTTCCTGAATGCGATTAATGCGATGCCCGAGGGTGGTGAGCTAGGCAT
TATCCTGGAACAGCAAGGCGATGAAGCGCTAGTTTGTATCAGGGACACGGGGACAGGGATCTTGGAAGGCGCACTGGATA
ATATCTTCGATCCTTTTCATACTTCCTCCCCGGCAGGAAAAGGAGTTGGACTCGGACTCTCTCTCTGTTATTCGATTGTT
AAACAACATAGGGGGAGTATTAGCGTGGATAGCATGGTGGGTAAGGGAAGCACTTTCACAGTATTGCTACCAATATTATG
A

Upstream 100 bases:

>100_bases
GAAGTCGATGTAGGTTACCTATTTTTAAGCGGCCCATGGCCCTCTATTACTTTTTTCATAAAGAGAAAACAACTATGGAT
ACGCTACTGGGAGATATTTT

Downstream 100 bases:

>100_bases
AATCGTCATCACGGCTTACCATTGACTGCCTCATTGTAGATGATGAGCCCGGCATCGCTTGGGTTATGGAACATATATTG
CGGAGTCAGGGTTACACTGT

Product: sensor histidine kinase PAS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MTDHDNLNLHATNGSVLKQSVSEKMGDNLQYQQLYDMLLNATPSSVLLIDSNFRITSANRNFLTRSQRTLSATIGCRLRE
VFPIVILERMDIKQQIQEVFNTHKASVGQRMTYRAPGVPFKTYYYRILPIESSEQCEQVMLLMEDITDQIRLSEDMRRVE
SHLGSIVESASDLMLSLDTEGRILTWNSAAEKLSGFTFLKVQGKFFFEFFKASEHLEIKTFFINICINVCSLNAEWELIS
KKGIEISVAWIFSPMKDDDAKTVGIVAVGRDLTEQRKLEVELRQSQKLAALGVMAGGIAHEIRNPLAVCSSAAQFLMEEG
LPLEFRTECAKKIQVSLEKASCIIENLLRFSRPSCEQNMVPMDLDTVLCETIMLIANQAKVYKIEIVYLPIGKCSLVSGI
FTLLQQVFMNFFLNAINAMPEGGELGIILEQQGDEALVCIRDTGTGILEGALDNIFDPFHTSSPAGKGVGLGLSLCYSIV
KQHRGSISVDSMVGKGSTFTVLLPIL

Sequences:

>Translated_506_residues
MTDHDNLNLHATNGSVLKQSVSEKMGDNLQYQQLYDMLLNATPSSVLLIDSNFRITSANRNFLTRSQRTLSATIGCRLRE
VFPIVILERMDIKQQIQEVFNTHKASVGQRMTYRAPGVPFKTYYYRILPIESSEQCEQVMLLMEDITDQIRLSEDMRRVE
SHLGSIVESASDLMLSLDTEGRILTWNSAAEKLSGFTFLKVQGKFFFEFFKASEHLEIKTFFINICINVCSLNAEWELIS
KKGIEISVAWIFSPMKDDDAKTVGIVAVGRDLTEQRKLEVELRQSQKLAALGVMAGGIAHEIRNPLAVCSSAAQFLMEEG
LPLEFRTECAKKIQVSLEKASCIIENLLRFSRPSCEQNMVPMDLDTVLCETIMLIANQAKVYKIEIVYLPIGKCSLVSGI
FTLLQQVFMNFFLNAINAMPEGGELGIILEQQGDEALVCIRDTGTGILEGALDNIFDPFHTSSPAGKGVGLGLSLCYSIV
KQHRGSISVDSMVGKGSTFTVLLPIL
>Mature_505_residues
TDHDNLNLHATNGSVLKQSVSEKMGDNLQYQQLYDMLLNATPSSVLLIDSNFRITSANRNFLTRSQRTLSATIGCRLREV
FPIVILERMDIKQQIQEVFNTHKASVGQRMTYRAPGVPFKTYYYRILPIESSEQCEQVMLLMEDITDQIRLSEDMRRVES
HLGSIVESASDLMLSLDTEGRILTWNSAAEKLSGFTFLKVQGKFFFEFFKASEHLEIKTFFINICINVCSLNAEWELISK
KGIEISVAWIFSPMKDDDAKTVGIVAVGRDLTEQRKLEVELRQSQKLAALGVMAGGIAHEIRNPLAVCSSAAQFLMEEGL
PLEFRTECAKKIQVSLEKASCIIENLLRFSRPSCEQNMVPMDLDTVLCETIMLIANQAKVYKIEIVYLPIGKCSLVSGIF
TLLQQVFMNFFLNAINAMPEGGELGIILEQQGDEALVCIRDTGTGILEGALDNIFDPFHTSSPAGKGVGLGLSLCYSIVK
QHRGSISVDSMVGKGSTFTVLLPIL

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=365, Percent_Identity=28.2191780821918, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1790436, Length=236, Percent_Identity=31.3559322033898, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI48994928, Length=261, Percent_Identity=27.5862068965517, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1786600, Length=375, Percent_Identity=23.4666666666667, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI145693157, Length=287, Percent_Identity=23.6933797909408, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790300, Length=256, Percent_Identity=30.078125, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790861, Length=198, Percent_Identity=26.2626262626263, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87081816, Length=249, Percent_Identity=28.1124497991968, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56415; Mature: 56284

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDHDNLNLHATNGSVLKQSVSEKMGDNLQYQQLYDMLLNATPSSVLLIDSNFRITSANR
CCCCCCCEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEECCEEEEECCC
NFLTRSQRTLSATIGCRLREVFPIVILERMDIKQQIQEVFNTHKASVGQRMTYRAPGVPF
CHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEECCCCCCE
KTYYYRILPIESSEQCEQVMLLMEDITDQIRLSEDMRRVESHLGSIVESASDLMLSLDTE
EEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCC
GRILTWNSAAEKLSGFTFLKVQGKFFFEFFKASEHLEIKTFFINICINVCSLNAEWELIS
CCEEEECCHHHHHCCEEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEE
KKGIEISVAWIFSPMKDDDAKTVGIVAVGRDLTEQRKLEVELRQSQKLAALGVMAGGIAH
CCCCEEEEEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
EIRNPLAVCSSAAQFLMEEGLPLEFRTECAKKIQVSLEKASCIIENLLRFSRPSCEQNMV
HHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PMDLDTVLCETIMLIANQAKVYKIEIVYLPIGKCSLVSGIFTLLQQVFMNFFLNAINAMP
CCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EGGELGIILEQQGDEALVCIRDTGTGILEGALDNIFDPFHTSSPAGKGVGLGLSLCYSIV
CCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
KQHRGSISVDSMVGKGSTFTVLLPIL
HHHCCCEEHHHHCCCCCEEEEEEECC
>Mature Secondary Structure 
TDHDNLNLHATNGSVLKQSVSEKMGDNLQYQQLYDMLLNATPSSVLLIDSNFRITSANR
CCCCCCEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEEECCEEEEECCC
NFLTRSQRTLSATIGCRLREVFPIVILERMDIKQQIQEVFNTHKASVGQRMTYRAPGVPF
CHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEECCCCCCE
KTYYYRILPIESSEQCEQVMLLMEDITDQIRLSEDMRRVESHLGSIVESASDLMLSLDTE
EEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCC
GRILTWNSAAEKLSGFTFLKVQGKFFFEFFKASEHLEIKTFFINICINVCSLNAEWELIS
CCEEEECCHHHHHCCEEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEE
KKGIEISVAWIFSPMKDDDAKTVGIVAVGRDLTEQRKLEVELRQSQKLAALGVMAGGIAH
CCCCEEEEEEEECCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
EIRNPLAVCSSAAQFLMEEGLPLEFRTECAKKIQVSLEKASCIIENLLRFSRPSCEQNMV
HHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PMDLDTVLCETIMLIANQAKVYKIEIVYLPIGKCSLVSGIFTLLQQVFMNFFLNAINAMP
CCCHHHHHHHHHHHHHCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EGGELGIILEQQGDEALVCIRDTGTGILEGALDNIFDPFHTSSPAGKGVGLGLSLCYSIV
CCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
KQHRGSISVDSMVGKGSTFTVLLPIL
HHHCCCEEHHHHCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]