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The map label for this gene is flp [H]

Identifier: 119945337

GI number: 119945337

Start: 1973864

End: 1975144

Strand: Direct

Name: flp [H]

Synonym: Ping_1621

Alternate gene names: 119945337

Gene position: 1973864-1975144 (Clockwise)

Preceding gene: 119945335

Following gene: 119945338

Centisome position: 43.29

GC content: 39.58

Gene sequence:

>1281_bases
ATGGCAGGCTTATATTTTGATAAACTGTTTTTTTTTGCAAAATCACCATTAGGGATGTTTTTGAAACATATAATAGTTTT
TTTTTTGACACTGCTTTTTTTAAGTACAATAGTACCTGTCTCCGCTAAATCAACCCCTCCTTCAAAAATAGAAATTGAGT
TCAATAAGCTGTTTAAGCGGGCTATGCGTGTGAATCACATTCCCGGTGCCACTTATGCCATTGTGCGAGGCGATCGCGTG
TCGACAATTAAAGCCTATGGAGTACGTGGACAAAAGAATAACAAAGCGATCGATAAAGATACCTCTTTTAGATTGGCCTC
GGTATCAAAAACATTTTCCGCTGAGTTGGCAGCGCTGATGATCGAAAAAAAATCATTTGCTTGGAACGATTCTATTGTCG
ATTATATTCCTGAATTTAAGCTTAAGCAGGCAGGTCAAGCCGAAGCTATTACCATCAAGCATGTGCTAAGCCACAGCAGC
GGATTAATGCCCAATGCCTTTGATGGTTATTTAAAAGGTGGTTTTCAATTTAGCCATATTATATCAAAATTTGAAGCTTT
AGAGCCTTATTGTTCACCTGGGGCATGTTACGGTTATCAGAATGTACTGTTTAGTTTTATAGCCGAAGTGTTTAAACGCA
GTACAGGTAAAGCATACGCTGAATTGATGCAACAGATGATTTTTTCCCCCTTAGCAATGAACAATGCCAGTGTCGGTTTT
GATGCTTATAAAAATACCACTAATAAAGCCTACCCTCATGTTAAAGTCAGCCGTAACGGGCCTTGGCATCAAGTAAAAAT
AAAACCAGATTTCTACAAAGTCGAGGCTGCAGCTGGTATCAATGCCAGCATTACGGATATGAGTAAATGGTTGCTTGCGC
AGTTGGGGCATACGCCAGAGGTAATTTCGGCGCATTTATTAGAGACAGTAAGGGAGCCTGTCGTTAGCACAGAGAAAGAT
GTAAAAAGTCGCACCTGGAAGGGCATCATTGATGATGCCCATTATGGTATTGGCTGGCGTGTTTACCAATATAATGAGGA
CATATTATATTTTCACAGTGGCTGGGTTGAAGGTTTTCGAGCGGTAATTGCCTATTCAAAAGATAAGCAGATAGGGTTAG
TTATATTGGCTAATGCTGAATCACGCAGTATTGATAAATTAACGGTGGATTTCTGGCGTTTGTTACTTAAAGAGCCTTCG
GTTAAGGAAACCCTATTAGTGAAGGATATTAAACCGGTTAAGGCAAACCGATCAGTGAAGGATATTAAATCGTCTTTCTA
A

Upstream 100 bases:

>100_bases
TAATAATTGTTTCATAATTAATACAATAAGTTGTGTCATTTAAGTTCTTTTATAGATAGATTTTGGTACCCAGATGCTGT
CTTTATTGGGTTATAGGGTG

Downstream 100 bases:

>100_bases
TAAAATACTGATGGCAGTCAACGCTTCAGGCTATCTCACCAACTAGTTATTTATTATATTTTTTTAAGATAGATCGGCTT
ATAAATATTTTATATGAAAT

Product: beta-lactamase

Products: A Substituted Beta- Amino Acid. [C]

Alternate protein names: FmtA-like protein [H]

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MAGLYFDKLFFFAKSPLGMFLKHIIVFFLTLLFLSTIVPVSAKSTPPSKIEIEFNKLFKRAMRVNHIPGATYAIVRGDRV
STIKAYGVRGQKNNKAIDKDTSFRLASVSKTFSAELAALMIEKKSFAWNDSIVDYIPEFKLKQAGQAEAITIKHVLSHSS
GLMPNAFDGYLKGGFQFSHIISKFEALEPYCSPGACYGYQNVLFSFIAEVFKRSTGKAYAELMQQMIFSPLAMNNASVGF
DAYKNTTNKAYPHVKVSRNGPWHQVKIKPDFYKVEAAAGINASITDMSKWLLAQLGHTPEVISAHLLETVREPVVSTEKD
VKSRTWKGIIDDAHYGIGWRVYQYNEDILYFHSGWVEGFRAVIAYSKDKQIGLVILANAESRSIDKLTVDFWRLLLKEPS
VKETLLVKDIKPVKANRSVKDIKSSF

Sequences:

>Translated_426_residues
MAGLYFDKLFFFAKSPLGMFLKHIIVFFLTLLFLSTIVPVSAKSTPPSKIEIEFNKLFKRAMRVNHIPGATYAIVRGDRV
STIKAYGVRGQKNNKAIDKDTSFRLASVSKTFSAELAALMIEKKSFAWNDSIVDYIPEFKLKQAGQAEAITIKHVLSHSS
GLMPNAFDGYLKGGFQFSHIISKFEALEPYCSPGACYGYQNVLFSFIAEVFKRSTGKAYAELMQQMIFSPLAMNNASVGF
DAYKNTTNKAYPHVKVSRNGPWHQVKIKPDFYKVEAAAGINASITDMSKWLLAQLGHTPEVISAHLLETVREPVVSTEKD
VKSRTWKGIIDDAHYGIGWRVYQYNEDILYFHSGWVEGFRAVIAYSKDKQIGLVILANAESRSIDKLTVDFWRLLLKEPS
VKETLLVKDIKPVKANRSVKDIKSSF
>Mature_425_residues
AGLYFDKLFFFAKSPLGMFLKHIIVFFLTLLFLSTIVPVSAKSTPPSKIEIEFNKLFKRAMRVNHIPGATYAIVRGDRVS
TIKAYGVRGQKNNKAIDKDTSFRLASVSKTFSAELAALMIEKKSFAWNDSIVDYIPEFKLKQAGQAEAITIKHVLSHSSG
LMPNAFDGYLKGGFQFSHIISKFEALEPYCSPGACYGYQNVLFSFIAEVFKRSTGKAYAELMQQMIFSPLAMNNASVGFD
AYKNTTNKAYPHVKVSRNGPWHQVKIKPDFYKVEAAAGINASITDMSKWLLAQLGHTPEVISAHLLETVREPVVSTEKDV
KSRTWKGIIDDAHYGIGWRVYQYNEDILYFHSGWVEGFRAVIAYSKDKQIGLVILANAESRSIDKLTVDFWRLLLKEPSV
KETLLVKDIKPVKANRSVKDIKSSF

Specific function: Its precise function is unknown. Has no penicillin- binding activity and is not involved in methicillin resistance [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790593, Length=383, Percent_Identity=21.9321148825065, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: 3.5.2.6 [C]

Molecular weight: Translated: 47932; Mature: 47801

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLYFDKLFFFAKSPLGMFLKHIIVFFLTLLFLSTIVPVSAKSTPPSKIEIEFNKLFKR
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHH
AMRVNHIPGATYAIVRGDRVSTIKAYGVRGQKNNKAIDKDTSFRLASVSKTFSAELAALM
HHHHCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHH
IEKKSFAWNDSIVDYIPEFKLKQAGQAEAITIKHVLSHSSGLMPNAFDGYLKGGFQFSHI
HHHCCCCCCCCHHHHCCCHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHH
ISKFEALEPYCSPGACYGYQNVLFSFIAEVFKRSTGKAYAELMQQMIFSPLAMNNASVGF
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHCCCCCCCC
DAYKNTTNKAYPHVKVSRNGPWHQVKIKPDFYKVEAAAGINASITDMSKWLLAQLGHTPE
HHHCCCCCCCCCEEEECCCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHCCCHH
VISAHLLETVREPVVSTEKDVKSRTWKGIIDDAHYGIGWRVYQYNEDILYFHSGWVEGFR
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEEEECCHHHHHH
AVIAYSKDKQIGLVILANAESRSIDKLTVDFWRLLLKEPSVKETLLVKDIKPVKANRSVK
HHHEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHH
DIKSSF
HHHHCC
>Mature Secondary Structure 
AGLYFDKLFFFAKSPLGMFLKHIIVFFLTLLFLSTIVPVSAKSTPPSKIEIEFNKLFKR
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEHHHHHHH
AMRVNHIPGATYAIVRGDRVSTIKAYGVRGQKNNKAIDKDTSFRLASVSKTFSAELAALM
HHHHCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHH
IEKKSFAWNDSIVDYIPEFKLKQAGQAEAITIKHVLSHSSGLMPNAFDGYLKGGFQFSHI
HHHCCCCCCCCHHHHCCCHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHH
ISKFEALEPYCSPGACYGYQNVLFSFIAEVFKRSTGKAYAELMQQMIFSPLAMNNASVGF
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHCCCCCCCC
DAYKNTTNKAYPHVKVSRNGPWHQVKIKPDFYKVEAAAGINASITDMSKWLLAQLGHTPE
HHHCCCCCCCCCEEEECCCCCEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHCCCHH
VISAHLLETVREPVVSTEKDVKSRTWKGIIDDAHYGIGWRVYQYNEDILYFHSGWVEGFR
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEEEECCHHHHHH
AVIAYSKDKQIGLVILANAESRSIDKLTVDFWRLLLKEPSVKETLLVKDIKPVKANRSVK
HHHEECCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHH
DIKSSF
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Beta-Lactam; H2O [C]

Specific reaction: A Beta-Lactam + H2O = A Substituted Beta- Amino Acid. [C]

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA