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The map label for this gene is clpX

Identifier: 119945202

GI number: 119945202

Start: 1811054

End: 1812331

Strand: Direct

Name: clpX

Synonym: Ping_1466

Alternate gene names: 119945202

Gene position: 1811054-1812331 (Clockwise)

Preceding gene: 119945201

Following gene: 119945203

Centisome position: 39.72

GC content: 38.5

Gene sequence:

>1278_bases
ATGCCAAATAAAAATGATAGTTTACTTTATTGTTCTTTTTGTGGAAAAAGTCAGCACGAAGTAAAAAAACTGATTGCCGG
TCCTTCTGTTTATATTTGTAATGAATGTGTTGATCTTTGTGATGATATTATCAAAGAAGAAATTGCAGAAATAAACAGTG
CAAGTGAATCGACAACGAGCGATAAAAAATTACCAACACCACATGAAATTCGTGACAATCTGGACGATTATGTTATTGGT
CAAGACACAGCAAAAAAAGTCTTGTCAGTTGCGGTATATAACCATTATAAGCGTTTAAAGCATGGTGCTATTTCTGATGG
TGTTGAGCTCAGTAAAAGTAATATTCTTCTGATTGGTCCAACGGGCAGTGGTAAAACACTGCTGGCAGAAACCATGGCGC
GGTTATTAGATGTCCCCTTTGCGATGGCCGATGCAACCACACTTACTGAAGCGGGTTATGTGGGTGAAGATGTTGAAAAC
ATTATTCAGAAGCTGTTACAAAAATGTGATTATGATGCAGAAAAAGCGCAACACGGTATTATCTACATCGATGAAATTGA
TAAGATAACCCGTAAATCAGAAAATCCGTCTATTACACGTGATGTTTCAGGTGAAGGTGTACAACAGGCGTTATTAAAAC
TGATTGAAGGTACAGTTGCTTCTATTCCCCCTCAGGGTGGCCGGAAACATCCAAATCAAGAGTTTATCCAAGTAGATACT
TCCAAGATACTGTTTATTTGTGGCGGTGCATTCTCAGGTTTAGATAGCGTCATTGAACAACGTGTTGATACGGGCACGGG
CATTGGTTTTGGTGCAACCGTAAGAGATAAAGATTCAAAAGCGACGATCAGTGAAACTTTTCAAAAAGTGTTGCCTCAGG
ATTTAATTAAATACGGTCTGATTCCTGAGTTTATAGGGCGGTTACCTGTTGTTGCAACATTAACGGAATTAGATGAACAC
GCATTAGTTGAAATATTAACGGCACCGAAAAATGCAATCACGAAACAATATGCTGCGTTATTTGGATTAGAAAATGTCGA
GCTTGAGTTTAGAGAAAATGCATTAATCGCAATGGCACAAAAAGCGATGGGCCGGAAAACTGGTGCACGTGGGCTGCGTT
CAATTGTTGAAGAGGTATTGTTAGATACTATGTATGACTTACCCTCGGTAAAAAATGTCAGTAAAGTTGTTATTGATGAA
AATGTCATTGCTGGTAAGGCAAAACCTCTACTGATTTATTCGGAAGAGCAAGAACGATTAGCATCGTCTGATAAATAA

Upstream 100 bases:

>100_bases
AAGATACAGATCGTGATAATTTTATGCGCGCAAGTGAAGCAGTAGAATACGGCATTGTTGATTCAGTGTTAACGCATAGA
AAATAAGTAAAGGAAAAAAA

Downstream 100 bases:

>100_bases
CCAATTAAACCAATAATTATTAAGAAAGAGAGCCTTGTGCTCTCTTTTTTCATTTATTACCTTGAAAAAAAAACTCCAAT
CCCCAGTATAGTTTACTACG

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MPNKNDSLLYCSFCGKSQHEVKKLIAGPSVYICNECVDLCDDIIKEEIAEINSASESTTSDKKLPTPHEIRDNLDDYVIG
QDTAKKVLSVAVYNHYKRLKHGAISDGVELSKSNILLIGPTGSGKTLLAETMARLLDVPFAMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDAEKAQHGIIYIDEIDKITRKSENPSITRDVSGEGVQQALLKLIEGTVASIPPQGGRKHPNQEFIQVDT
SKILFICGGAFSGLDSVIEQRVDTGTGIGFGATVRDKDSKATISETFQKVLPQDLIKYGLIPEFIGRLPVVATLTELDEH
ALVEILTAPKNAITKQYAALFGLENVELEFRENALIAMAQKAMGRKTGARGLRSIVEEVLLDTMYDLPSVKNVSKVVIDE
NVIAGKAKPLLIYSEEQERLASSDK

Sequences:

>Translated_425_residues
MPNKNDSLLYCSFCGKSQHEVKKLIAGPSVYICNECVDLCDDIIKEEIAEINSASESTTSDKKLPTPHEIRDNLDDYVIG
QDTAKKVLSVAVYNHYKRLKHGAISDGVELSKSNILLIGPTGSGKTLLAETMARLLDVPFAMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDAEKAQHGIIYIDEIDKITRKSENPSITRDVSGEGVQQALLKLIEGTVASIPPQGGRKHPNQEFIQVDT
SKILFICGGAFSGLDSVIEQRVDTGTGIGFGATVRDKDSKATISETFQKVLPQDLIKYGLIPEFIGRLPVVATLTELDEH
ALVEILTAPKNAITKQYAALFGLENVELEFRENALIAMAQKAMGRKTGARGLRSIVEEVLLDTMYDLPSVKNVSKVVIDE
NVIAGKAKPLLIYSEEQERLASSDK
>Mature_424_residues
PNKNDSLLYCSFCGKSQHEVKKLIAGPSVYICNECVDLCDDIIKEEIAEINSASESTTSDKKLPTPHEIRDNLDDYVIGQ
DTAKKVLSVAVYNHYKRLKHGAISDGVELSKSNILLIGPTGSGKTLLAETMARLLDVPFAMADATTLTEAGYVGEDVENI
IQKLLQKCDYDAEKAQHGIIYIDEIDKITRKSENPSITRDVSGEGVQQALLKLIEGTVASIPPQGGRKHPNQEFIQVDTS
KILFICGGAFSGLDSVIEQRVDTGTGIGFGATVRDKDSKATISETFQKVLPQDLIKYGLIPEFIGRLPVVATLTELDEHA
LVEILTAPKNAITKQYAALFGLENVELEFRENALIAMAQKAMGRKTGARGLRSIVEEVLLDTMYDLPSVKNVSKVVIDEN
VIAGKAKPLLIYSEEQERLASSDK

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=336, Percent_Identity=49.1071428571429, Blast_Score=302, Evalue=4e-82,
Organism=Escherichia coli, GI1786642, Length=417, Percent_Identity=76.7386091127098, Blast_Score=661, Evalue=0.0,
Organism=Escherichia coli, GI1790366, Length=106, Percent_Identity=43.3962264150943, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=311, Percent_Identity=45.016077170418, Blast_Score=265, Evalue=5e-71,
Organism=Caenorhabditis elegans, GI71982905, Length=311, Percent_Identity=44.6945337620579, Blast_Score=264, Evalue=6e-71,
Organism=Caenorhabditis elegans, GI71988663, Length=390, Percent_Identity=38.4615384615385, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI71988660, Length=247, Percent_Identity=39.2712550607287, Blast_Score=169, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=424, Percent_Identity=39.1509433962264, Blast_Score=260, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24648291, Length=335, Percent_Identity=46.2686567164179, Blast_Score=288, Evalue=5e-78,
Organism=Drosophila melanogaster, GI24648289, Length=335, Percent_Identity=46.2686567164179, Blast_Score=288, Evalue=6e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_PSYIN (A1SUW8)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_942882.1
- ProteinModelPortal:   A1SUW8
- STRING:   A1SUW8
- GeneID:   4626025
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_1466
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- PhylomeDB:   A1SUW8
- ProtClustDB:   PRK05342
- BioCyc:   PING357804:PING_1466-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 46442; Mature: 46310

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNKNDSLLYCSFCGKSQHEVKKLIAGPSVYICNECVDLCDDIIKEEIAEINSASESTTS
CCCCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DKKLPTPHEIRDNLDDYVIGQDTAKKVLSVAVYNHYKRLKHGAISDGVELSKSNILLIGP
CCCCCCCHHHHCCCHHEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEEEC
TGSGKTLLAETMARLLDVPFAMADATTLTEAGYVGEDVENIIQKLLQKCDYDAEKAQHGI
CCCCCHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCE
IYIDEIDKITRKSENPSITRDVSGEGVQQALLKLIEGTVASIPPQGGRKHPNQEFIQVDT
EEEECHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCCCHHEEECC
SKILFICGGAFSGLDSVIEQRVDTGTGIGFGATVRDKDSKATISETFQKVLPQDLIKYGL
CEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCC
IPEFIGRLPVVATLTELDEHALVEILTAPKNAITKQYAALFGLENVELEFRENALIAMAQ
CHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHH
KAMGRKTGARGLRSIVEEVLLDTMYDLPSVKNVSKVVIDENVIAGKAKPLLIYSEEQERL
HHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEECCCCCEEEEECCHHHHH
ASSDK
CCCCC
>Mature Secondary Structure 
PNKNDSLLYCSFCGKSQHEVKKLIAGPSVYICNECVDLCDDIIKEEIAEINSASESTTS
CCCCCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DKKLPTPHEIRDNLDDYVIGQDTAKKVLSVAVYNHYKRLKHGAISDGVELSKSNILLIGP
CCCCCCCHHHHCCCHHEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEEEC
TGSGKTLLAETMARLLDVPFAMADATTLTEAGYVGEDVENIIQKLLQKCDYDAEKAQHGI
CCCCCHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCE
IYIDEIDKITRKSENPSITRDVSGEGVQQALLKLIEGTVASIPPQGGRKHPNQEFIQVDT
EEEECHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCCCHHEEECC
SKILFICGGAFSGLDSVIEQRVDTGTGIGFGATVRDKDSKATISETFQKVLPQDLIKYGL
CEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCC
IPEFIGRLPVVATLTELDEHALVEILTAPKNAITKQYAALFGLENVELEFRENALIAMAQ
CHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHH
KAMGRKTGARGLRSIVEEVLLDTMYDLPSVKNVSKVVIDENVIAGKAKPLLIYSEEQERL
HHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEECCCCCEEEEECCHHHHH
ASSDK
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA