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The map label for this gene is ung

Identifier: 119945029

GI number: 119945029

Start: 1589341

End: 1589991

Strand: Direct

Name: ung

Synonym: Ping_1283

Alternate gene names: 119945029

Gene position: 1589341-1589991 (Clockwise)

Preceding gene: 119945026

Following gene: 119945030

Centisome position: 34.86

GC content: 37.02

Gene sequence:

>651_bases
ATGAGCTGGAAGAAATTTATTACACAGCAAGAATCGATGGAATATTACAATGCTCTTCAGGCATTTTTAAAATCTCAAAA
AGAGTTAGGAAAAAATATTTATCCGCCTGAGCATCTTGTTTTTAATGCATTTAATTTAACTCCGTTAGAAAATATTAAAG
TGGTTATTCTAGGGCAGGATCCTTATCATCGCGAAGGGCAGTCCCATGGTCTTAGTTTTTCGGTGCCAGAAGGTATTAAA
ATTCCACCTTCACTGCGTAATATTTATAAAGAATTATCCACTTCTATCGAAGGCTATAAAATACCTGAATCAGGCAATTT
AGCGCATTGGGCAAAACAAGGTATTTTACTGTTAAATTCAGTGTTAACGGTGGAACAGGCAGATCCTGGCTGCCATGCAA
AAAAAGGATGGGAAACCTTCACTGATAATGCGATTAGTGAAATAAATAATGCGCGTAGTGGTGTGATATTTTTATTGTGG
GGAAGTTACGCCCATAAAAAGGGAAGTCTAATAGATAAAAATAAGCATACGGTTTTAACCTCAACACACCCCTCGCCTTT
GTCTGCATATCGAGGATTCTTAGGTTGTAAGCATTTTAGTCAAGTGAATGACATATTGGCTGAACGGCGGGAACAATTAA
TTATCTGGTAA

Upstream 100 bases:

>100_bases
CATTCTGTCACCAAAATATTGTATTGGATTCATTTTCGTTGTTAAATAACCAAATTTTCATCCATAATAATTTTTGTCAA
TATAAAATAAAGAGGAAAAT

Downstream 100 bases:

>100_bases
TGTGACATAGTTCTGCGCTTTATTCTCGTTTAGCTGATATAATTATGATCTTGAATTTATAAATTTATGAGTATCTATTA
TGCTGTCTACTATCCATAAA

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MSWKKFITQQESMEYYNALQAFLKSQKELGKNIYPPEHLVFNAFNLTPLENIKVVILGQDPYHREGQSHGLSFSVPEGIK
IPPSLRNIYKELSTSIEGYKIPESGNLAHWAKQGILLLNSVLTVEQADPGCHAKKGWETFTDNAISEINNARSGVIFLLW
GSYAHKKGSLIDKNKHTVLTSTHPSPLSAYRGFLGCKHFSQVNDILAERREQLIIW

Sequences:

>Translated_216_residues
MSWKKFITQQESMEYYNALQAFLKSQKELGKNIYPPEHLVFNAFNLTPLENIKVVILGQDPYHREGQSHGLSFSVPEGIK
IPPSLRNIYKELSTSIEGYKIPESGNLAHWAKQGILLLNSVLTVEQADPGCHAKKGWETFTDNAISEINNARSGVIFLLW
GSYAHKKGSLIDKNKHTVLTSTHPSPLSAYRGFLGCKHFSQVNDILAERREQLIIW
>Mature_215_residues
SWKKFITQQESMEYYNALQAFLKSQKELGKNIYPPEHLVFNAFNLTPLENIKVVILGQDPYHREGQSHGLSFSVPEGIKI
PPSLRNIYKELSTSIEGYKIPESGNLAHWAKQGILLLNSVLTVEQADPGCHAKKGWETFTDNAISEINNARSGVIFLLWG
SYAHKKGSLIDKNKHTVLTSTHPSPLSAYRGFLGCKHFSQVNDILAERREQLIIW

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family

Homologues:

Organism=Homo sapiens, GI19718751, Length=215, Percent_Identity=49.7674418604651, Blast_Score=226, Evalue=9e-60,
Organism=Homo sapiens, GI6224979, Length=215, Percent_Identity=49.7674418604651, Blast_Score=226, Evalue=1e-59,
Organism=Escherichia coli, GI1788934, Length=217, Percent_Identity=54.3778801843318, Blast_Score=242, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI17556304, Length=216, Percent_Identity=48.6111111111111, Blast_Score=219, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6323620, Length=234, Percent_Identity=39.7435897435897, Blast_Score=162, Evalue=6e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UNG_PSYIN (A1SUE5)

Other databases:

- EMBL:   CP000510
- RefSeq:   YP_942709.1
- ProteinModelPortal:   A1SUE5
- SMR:   A1SUE5
- STRING:   A1SUE5
- GeneID:   4626761
- GenomeReviews:   CP000510_GR
- KEGG:   pin:Ping_1283
- eggNOG:   COG0692
- HOGENOM:   HBG605450
- OMA:   GAHAQKK
- PhylomeDB:   A1SUE5
- BioCyc:   PING357804:PING_1283-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00148
- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122
- Gene3D:   G3DSA:3.40.470.10
- PANTHER:   PTHR11264
- TIGRFAMs:   TIGR00628

Pfam domain/function: PF03167 UDG; SSF52141 UDNA_glycsylseSF

EC number: =3.2.2.27

Molecular weight: Translated: 24435; Mature: 24304

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: ACT_SITE 60-60

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWKKFITQQESMEYYNALQAFLKSQKELGKNIYPPEHLVFNAFNLTPLENIKVVILGQD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEECCCCCCCCEEEEEECCC
PYHREGQSHGLSFSVPEGIKIPPSLRNIYKELSTSIEGYKIPESGNLAHWAKQGILLLNS
CCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHH
VLTVEQADPGCHAKKGWETFTDNAISEINNARSGVIFLLWGSYAHKKGSLIDKNKHTVLT
HHHEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEECCCCCEEEE
STHPSPLSAYRGFLGCKHFSQVNDILAERREQLIIW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure 
SWKKFITQQESMEYYNALQAFLKSQKELGKNIYPPEHLVFNAFNLTPLENIKVVILGQD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEECCCCCCCCEEEEEECCC
PYHREGQSHGLSFSVPEGIKIPPSLRNIYKELSTSIEGYKIPESGNLAHWAKQGILLLNS
CCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHH
VLTVEQADPGCHAKKGWETFTDNAISEINNARSGVIFLLWGSYAHKKGSLIDKNKHTVLT
HHHEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEECCCCCEEEE
STHPSPLSAYRGFLGCKHFSQVNDILAERREQLIIW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA