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The map label for this gene is atoS [H]

Identifier: 119944999

GI number: 119944999

Start: 1560575

End: 1562095

Strand: Direct

Name: atoS [H]

Synonym: Ping_1250

Alternate gene names: 119944999

Gene position: 1560575-1562095 (Clockwise)

Preceding gene: 119944998

Following gene: 119945000

Centisome position: 34.23

GC content: 45.69

Gene sequence:

>1521_bases
ATGACTAATCATTATAGTTTAAACCTCCTTGCGAGTAATCACTCCGTTGCGAAACAGCCGGCGTCAGAGAGCACGGGAGA
CAATGTACAATACCAGCAGCTCTACGATATGCTGCTTAATGCGACTCCCTCTTCCATATTATTAATCGACAGCAAGTTAC
GTATTACCTCGGCTAATCGCAATTTCCTCACTCGAAGTCAGCGCACTCTTTCCGCGACAATAGGTTGCCGGCTTACAGAA
GTCTTTCCGATGGTTATTCTGGAACGAACGGATATCAAGCAACAGATCTTAGAAGTATTTAATACTCACAAGGCTTCTGT
TGGACGACGTATGACCTATCGGGCCCCCGGCGTGCCATTTAAAACCTATTACTATCGTATCTTGCCCGTAGAATCCAGCG
AGCAGTGCGAACAAGTCATGTTACTGATGGAAGATGTTACCGATCAGATCCGCCTCAGTGAAGATATGCGCCGTATGGAA
AGTCACCTTGGTAGCATTGTGGAAAGTGCTAGCGACCTAATGCTGTCTTTAGATACCGAAGGGCGTATCTTAACCTGGAA
CTTGGCGGCAGAAAAACTCTCAGGTTTTACTTTTCTAAACGTTAAAGGGAAGTTGTTTTTCGAGTTTTTCAAAGCCTCTG
AGCATTTAGAGATCAAGACGCTTTTTATCAACATATGTATCCATGTTTACTCCTTGAACGCCGAGTTGGAGTTGATCTCC
GGGGAAGGCACTGAAATCCCAGTCGCCTGGGTTTTCTCGCCGATGAAAGATGACGATGCCAAAACCGTAGGCATTGTTGC
TGTCGGGCGGGATCTGACCGAACAACGCAAGTTGGAGGTCGAGTTACGGCAGTCACAAAAACTCGCTGCGCTGGGGGTAA
TGGCTGGCGGTATCGCTCATGAAATCCGTAACCCTCTTGCAGTTTGTTCCTCAGCGGCGCAATTTCTGATGGAAGAGGGG
CTTCCTCTTGAATTTAGAACCGAATGTGCGGAGAAAATCCAAGTCAGTCTTGAGAAGGCTTCCTGCATCATTGAAAACTT
GCTGCGATTTTCCAGACCTTCCAGCGAACAAAATATGGTGCCGGTAGATCTGGATACTGTGCTATGCGAAACAATTATGT
TGATCGCAAACCAAGCCAAGGTATATAAAATTGAAATAGTCTATCAGCCTATTGGAAAATGTGGGTCGGTGTCTGGAATA
TTCACCCTGCTACAGCAAGTCTTTATGAATTTTTTCCTTAATGCCATTAATGCTATGCCCCATGGTGGGAAGCTAAGTAT
CATTCTGGAGCAACAAAACGATGAAGCGCGTATTTGTATCAGGGACACGGGGACTGGGATTTTGGAAGGTGCGCTGGATA
ATATCTTTGATCCTTTTCATACTTCCTCTCCTGCAGGAAAAGGCGTTGGACTCGGACTTTCTCTCTGTTATTCGATTGTC
AAACAACATCGGGGTAGTATTAGCGTGGATAGCATGCTCGGTAAGGGAAGCACTTTCACAGTATTGTTACCAGCATTATG
A

Upstream 100 bases:

>100_bases
AACTCGATATAGGTTACCTATTTTTAAGCGGTCCATGGCCTCCCTATCACTTTGTACATAAAGAAAAATCAAGCATGGAT
ATGCTACTGGAAGATATTTT

Downstream 100 bases:

>100_bases
AATCGCCATCACAGCTTACCATCGACTGTCTCATCGTAGATGATGAACCCGGTATAGCTTGGGTCATGGAACATATATTG
CGGGGTCAGGGTTACACAGT

Product: sensor histidine kinase PAS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MTNHYSLNLLASNHSVAKQPASESTGDNVQYQQLYDMLLNATPSSILLIDSKLRITSANRNFLTRSQRTLSATIGCRLTE
VFPMVILERTDIKQQILEVFNTHKASVGRRMTYRAPGVPFKTYYYRILPVESSEQCEQVMLLMEDVTDQIRLSEDMRRME
SHLGSIVESASDLMLSLDTEGRILTWNLAAEKLSGFTFLNVKGKLFFEFFKASEHLEIKTLFINICIHVYSLNAELELIS
GEGTEIPVAWVFSPMKDDDAKTVGIVAVGRDLTEQRKLEVELRQSQKLAALGVMAGGIAHEIRNPLAVCSSAAQFLMEEG
LPLEFRTECAEKIQVSLEKASCIIENLLRFSRPSSEQNMVPVDLDTVLCETIMLIANQAKVYKIEIVYQPIGKCGSVSGI
FTLLQQVFMNFFLNAINAMPHGGKLSIILEQQNDEARICIRDTGTGILEGALDNIFDPFHTSSPAGKGVGLGLSLCYSIV
KQHRGSISVDSMLGKGSTFTVLLPAL

Sequences:

>Translated_506_residues
MTNHYSLNLLASNHSVAKQPASESTGDNVQYQQLYDMLLNATPSSILLIDSKLRITSANRNFLTRSQRTLSATIGCRLTE
VFPMVILERTDIKQQILEVFNTHKASVGRRMTYRAPGVPFKTYYYRILPVESSEQCEQVMLLMEDVTDQIRLSEDMRRME
SHLGSIVESASDLMLSLDTEGRILTWNLAAEKLSGFTFLNVKGKLFFEFFKASEHLEIKTLFINICIHVYSLNAELELIS
GEGTEIPVAWVFSPMKDDDAKTVGIVAVGRDLTEQRKLEVELRQSQKLAALGVMAGGIAHEIRNPLAVCSSAAQFLMEEG
LPLEFRTECAEKIQVSLEKASCIIENLLRFSRPSSEQNMVPVDLDTVLCETIMLIANQAKVYKIEIVYQPIGKCGSVSGI
FTLLQQVFMNFFLNAINAMPHGGKLSIILEQQNDEARICIRDTGTGILEGALDNIFDPFHTSSPAGKGVGLGLSLCYSIV
KQHRGSISVDSMLGKGSTFTVLLPAL
>Mature_505_residues
TNHYSLNLLASNHSVAKQPASESTGDNVQYQQLYDMLLNATPSSILLIDSKLRITSANRNFLTRSQRTLSATIGCRLTEV
FPMVILERTDIKQQILEVFNTHKASVGRRMTYRAPGVPFKTYYYRILPVESSEQCEQVMLLMEDVTDQIRLSEDMRRMES
HLGSIVESASDLMLSLDTEGRILTWNLAAEKLSGFTFLNVKGKLFFEFFKASEHLEIKTLFINICIHVYSLNAELELISG
EGTEIPVAWVFSPMKDDDAKTVGIVAVGRDLTEQRKLEVELRQSQKLAALGVMAGGIAHEIRNPLAVCSSAAQFLMEEGL
PLEFRTECAEKIQVSLEKASCIIENLLRFSRPSSEQNMVPVDLDTVLCETIMLIANQAKVYKIEIVYQPIGKCGSVSGIF
TLLQQVFMNFFLNAINAMPHGGKLSIILEQQNDEARICIRDTGTGILEGALDNIFDPFHTSSPAGKGVGLGLSLCYSIVK
QHRGSISVDSMLGKGSTFTVLLPAL

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=358, Percent_Identity=28.2122905027933, Blast_Score=148, Evalue=7e-37,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=32.3404255319149, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI48994928, Length=363, Percent_Identity=24.5179063360882, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786600, Length=374, Percent_Identity=22.7272727272727, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI145693157, Length=287, Percent_Identity=24.7386759581882, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1790861, Length=198, Percent_Identity=25.7575757575758, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790300, Length=246, Percent_Identity=28.4552845528455, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788393, Length=215, Percent_Identity=26.046511627907, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 56179; Mature: 56048

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNHYSLNLLASNHSVAKQPASESTGDNVQYQQLYDMLLNATPSSILLIDSKLRITSANR
CCCEEEEEEEECCCCHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECEEEEEECCC
NFLTRSQRTLSATIGCRLTEVFPMVILERTDIKQQILEVFNTHKASVGRRMTYRAPGVPF
CHHHCCCHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEECCCCCCE
KTYYYRILPVESSEQCEQVMLLMEDVTDQIRLSEDMRRMESHLGSIVESASDLMLSLDTE
EEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
GRILTWNLAAEKLSGFTFLNVKGKLFFEFFKASEHLEIKTLFINICIHVYSLNAELELIS
CEEEEEEEHHHHHCCEEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHEEEEECCEEEEEE
GEGTEIPVAWVFSPMKDDDAKTVGIVAVGRDLTEQRKLEVELRQSQKLAALGVMAGGIAH
CCCCEEEEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
EIRNPLAVCSSAAQFLMEEGLPLEFRTECAEKIQVSLEKASCIIENLLRFSRPSSEQNMV
HHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
PVDLDTVLCETIMLIANQAKVYKIEIVYQPIGKCGSVSGIFTLLQQVFMNFFLNAINAMP
EECHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
HGGKLSIILEQQNDEARICIRDTGTGILEGALDNIFDPFHTSSPAGKGVGLGLSLCYSIV
CCCEEEEEEEECCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
KQHRGSISVDSMLGKGSTFTVLLPAL
HHHCCCEEHHHHCCCCCEEEEEECCC
>Mature Secondary Structure 
TNHYSLNLLASNHSVAKQPASESTGDNVQYQQLYDMLLNATPSSILLIDSKLRITSANR
CCEEEEEEEECCCCHHCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECEEEEEECCC
NFLTRSQRTLSATIGCRLTEVFPMVILERTDIKQQILEVFNTHKASVGRRMTYRAPGVPF
CHHHCCCHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEECCCCCCE
KTYYYRILPVESSEQCEQVMLLMEDVTDQIRLSEDMRRMESHLGSIVESASDLMLSLDTE
EEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCC
GRILTWNLAAEKLSGFTFLNVKGKLFFEFFKASEHLEIKTLFINICIHVYSLNAELELIS
CEEEEEEEHHHHHCCEEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHEEEEECCEEEEEE
GEGTEIPVAWVFSPMKDDDAKTVGIVAVGRDLTEQRKLEVELRQSQKLAALGVMAGGIAH
CCCCEEEEEEEECCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
EIRNPLAVCSSAAQFLMEEGLPLEFRTECAEKIQVSLEKASCIIENLLRFSRPSSEQNMV
HHHCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
PVDLDTVLCETIMLIANQAKVYKIEIVYQPIGKCGSVSGIFTLLQQVFMNFFLNAINAMP
EECHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
HGGKLSIILEQQNDEARICIRDTGTGILEGALDNIFDPFHTSSPAGKGVGLGLSLCYSIV
CCCEEEEEEEECCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHH
KQHRGSISVDSMLGKGSTFTVLLPAL
HHHCCCEEHHHHCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]