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The map label for this gene is hoxF [H]

Identifier: 119944968

GI number: 119944968

Start: 1519587

End: 1521353

Strand: Reverse

Name: hoxF [H]

Synonym: Ping_1217

Alternate gene names: 119944968

Gene position: 1521353-1519587 (Counterclockwise)

Preceding gene: 119944974

Following gene: 119944967

Centisome position: 33.37

GC content: 45.05

Gene sequence:

>1767_bases
ATGAATAAAGCTCTTGCCACACTGATTCAGGCACAAGTTAAAGTCTATCGGGGCGACCCTACTTATATATTACAAATACT
GCGGCATATTCAATTTTCCTGCTCACATATTCCCCAGCAGGCGATCCAGCAACTTGCCACTACATTGAGCATATCAATCC
CTAAAATCAGGGCGCTTATCGAGTTTTATCACTTTCTCCATTATCACCCTCGAGGCGATTATGATATCTACATCAGCGAT
AGCATCATCGACCATATGTCGGGTAAAAATGAAATCAGCAACTATCTCTGTGAAAAACTCAATGTTAAATTAAATCAGCC
CAGAGCGGACGGACGGGTAACTGTCTCTAACACTTCCTGTACAGGCATGAGTGATCAGGGACCTGCTGCATTGATTAATG
GTCTAGCATTGACCCGCCTGACCCGGAAAAAAGTCGATCAGATTGTTACGAAAATTGAAGGAAAGATTGCCATTGATAGG
TGGCCAAAGGCATGGTTTGAGGTAACTGATAATATCCAAAGTAAAGGCGTGTTATTAAATTCGGAAAGCAGACCCGGGGA
GGCGATTAAAAAAGCACTGGCAACAGCGCCTCACGACAGCCTTGCCGAAATTGACAAGTCCGGGCTGCGCGGCTGCGGTG
GTGCCGGTTTTAAAACTGCTGAAAAATGGAAGTCCTGTCTGTTAAGCGACGATAATCAACGTTATGTGGTATGTAATGCC
GATGAAGGTGAACCCGGTACTTTTAAAGATCGCGTTTTACTGAACAGTTATGCCGATCTGTTAATTGAAGGAATGACCCT
TTGTGCCTATGTTATTGGCGCTCAAAAAGGGTTTATTTATCTGCGTTATGAATATCAGCACCTCTATAAAAAGCTTCTGG
AAACATTACAGAGACGCCGCGCTGCCAACCTATTAGGCGCGCATATTTTAAACAGTGAGCTGAGTTTTGATATTGAAATA
TTTATGGGTGCCGGCTCCTATGTCTGCGGTGAAGAATCGGCTTTGCTCGAATCCCTTGAAGGCCGTCGTGCCATTCCACG
CATCCGCCCCCCTTTTCCCGTGACGCATGGTTACTTAGATAAACCAACAGTGGTCAACAATGTAGAAACCTTTTGTTATG
CCGCGCTTATTATAGAAAAAGGCGCTGAAAATTTTTCTGCTCAAGGGCTTGCCGGCTTTACTGGTTGTAAAATTTTAAGC
ATCAGCGGCGACGTGGAAAAAACGGGGATTTACGAGATCCCCTTGGGACTGCCAGTGAAAAATGTGCTCAATTTATGCGG
CGCACAATCTGTTCAAGCGGTGCAGGTTGGCGGCCCTTCCGGTACTTTGATTACCCCAGCTGAATTTAGCCGCGTAATTT
CATTTGATGATCTCCATACCGGCGGCTCTTTTATGGTGTTTAACCAAAGCCGCGATATCCTTGAAAATGCGCTTAACTTT
ACCCATTTTTTTATGCAGGAAAGCTGCGGCTTCTGTACGCCCTGCCGCGTAGGCACTAAGCTAATCTATGATTTGGCCGA
TAAAGTTGCCACCGGGCAAGGCGCCAGACTGGATCTGGACAGCATCAAGCAGCTTAACCATGTGATGAATGGAATGAGCC
ATTGCGGATTAGGACAAAGAGCGGCAGAGCCCCTATTAGAAACATTAGAAAAATTTCCCGAGTATTTTGTTAAACGCATG
ACAGATATTGAGTATCAGCCTTCCTTTGATGTGGAAAAATCAATTCAGCGGGCGATTGATATCGTCACCATAGAGAGTAA
TTCATAG

Upstream 100 bases:

>100_bases
AATGACACTTGTTAATTATCTGCGCCATTAAGCCGCAATAAAAGGTCTTAATAGTTAAATCAAGCATGCTGTGCTGAGCA
CTCATTAGGAGCATTTAATA

Downstream 100 bases:

>100_bases
GGTTATTAATGGTTATGAGCAATCACAGCAACACCTTCAGCATAGATGGCCGGGAGATCCCTTTTATAGCGGGAGAGACC
GTTATGCAGGCCGCGCTTAA

Product: hydrogenase, NADP-reducing subunit C

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MNKALATLIQAQVKVYRGDPTYILQILRHIQFSCSHIPQQAIQQLATTLSISIPKIRALIEFYHFLHYHPRGDYDIYISD
SIIDHMSGKNEISNYLCEKLNVKLNQPRADGRVTVSNTSCTGMSDQGPAALINGLALTRLTRKKVDQIVTKIEGKIAIDR
WPKAWFEVTDNIQSKGVLLNSESRPGEAIKKALATAPHDSLAEIDKSGLRGCGGAGFKTAEKWKSCLLSDDNQRYVVCNA
DEGEPGTFKDRVLLNSYADLLIEGMTLCAYVIGAQKGFIYLRYEYQHLYKKLLETLQRRRAANLLGAHILNSELSFDIEI
FMGAGSYVCGEESALLESLEGRRAIPRIRPPFPVTHGYLDKPTVVNNVETFCYAALIIEKGAENFSAQGLAGFTGCKILS
ISGDVEKTGIYEIPLGLPVKNVLNLCGAQSVQAVQVGGPSGTLITPAEFSRVISFDDLHTGGSFMVFNQSRDILENALNF
THFFMQESCGFCTPCRVGTKLIYDLADKVATGQGARLDLDSIKQLNHVMNGMSHCGLGQRAAEPLLETLEKFPEYFVKRM
TDIEYQPSFDVEKSIQRAIDIVTIESNS

Sequences:

>Translated_588_residues
MNKALATLIQAQVKVYRGDPTYILQILRHIQFSCSHIPQQAIQQLATTLSISIPKIRALIEFYHFLHYHPRGDYDIYISD
SIIDHMSGKNEISNYLCEKLNVKLNQPRADGRVTVSNTSCTGMSDQGPAALINGLALTRLTRKKVDQIVTKIEGKIAIDR
WPKAWFEVTDNIQSKGVLLNSESRPGEAIKKALATAPHDSLAEIDKSGLRGCGGAGFKTAEKWKSCLLSDDNQRYVVCNA
DEGEPGTFKDRVLLNSYADLLIEGMTLCAYVIGAQKGFIYLRYEYQHLYKKLLETLQRRRAANLLGAHILNSELSFDIEI
FMGAGSYVCGEESALLESLEGRRAIPRIRPPFPVTHGYLDKPTVVNNVETFCYAALIIEKGAENFSAQGLAGFTGCKILS
ISGDVEKTGIYEIPLGLPVKNVLNLCGAQSVQAVQVGGPSGTLITPAEFSRVISFDDLHTGGSFMVFNQSRDILENALNF
THFFMQESCGFCTPCRVGTKLIYDLADKVATGQGARLDLDSIKQLNHVMNGMSHCGLGQRAAEPLLETLEKFPEYFVKRM
TDIEYQPSFDVEKSIQRAIDIVTIESNS
>Mature_588_residues
MNKALATLIQAQVKVYRGDPTYILQILRHIQFSCSHIPQQAIQQLATTLSISIPKIRALIEFYHFLHYHPRGDYDIYISD
SIIDHMSGKNEISNYLCEKLNVKLNQPRADGRVTVSNTSCTGMSDQGPAALINGLALTRLTRKKVDQIVTKIEGKIAIDR
WPKAWFEVTDNIQSKGVLLNSESRPGEAIKKALATAPHDSLAEIDKSGLRGCGGAGFKTAEKWKSCLLSDDNQRYVVCNA
DEGEPGTFKDRVLLNSYADLLIEGMTLCAYVIGAQKGFIYLRYEYQHLYKKLLETLQRRRAANLLGAHILNSELSFDIEI
FMGAGSYVCGEESALLESLEGRRAIPRIRPPFPVTHGYLDKPTVVNNVETFCYAALIIEKGAENFSAQGLAGFTGCKILS
ISGDVEKTGIYEIPLGLPVKNVLNLCGAQSVQAVQVGGPSGTLITPAEFSRVISFDDLHTGGSFMVFNQSRDILENALNF
THFFMQESCGFCTPCRVGTKLIYDLADKVATGQGARLDLDSIKQLNHVMNGMSHCGLGQRAAEPLLETLEKFPEYFVKRM
TDIEYQPSFDVEKSIQRAIDIVTIESNS

Specific function: Subunits alpha and gamma of hoxS constitute an NADH-- oxidoreductase [H]

COG id: COG1894

COG function: function code C; NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 51 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI20149568, Length=385, Percent_Identity=35.0649350649351, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI260656005, Length=385, Percent_Identity=35.0649350649351, Blast_Score=219, Evalue=5e-57,
Organism=Escherichia coli, GI1788620, Length=385, Percent_Identity=36.1038961038961, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI1788621, Length=151, Percent_Identity=26.4900662251656, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17531727, Length=380, Percent_Identity=34.2105263157895, Blast_Score=214, Evalue=7e-56,
Organism=Drosophila melanogaster, GI19920794, Length=372, Percent_Identity=33.8709677419355, Blast_Score=213, Evalue=3e-55,
Organism=Drosophila melanogaster, GI45550452, Length=372, Percent_Identity=33.6021505376344, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24653819, Length=343, Percent_Identity=30.0291545189504, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24653817, Length=305, Percent_Identity=29.1803278688525, Blast_Score=136, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001949
- InterPro:   IPR019575
- InterPro:   IPR002023
- InterPro:   IPR011538
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa; PF01512 Complex1_51K; PF10589 NADH_4Fe-4S [H]

EC number: =1.12.1.2 [H]

Molecular weight: Translated: 65085; Mature: 65085

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS00645 COMPLEX1_51K_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKALATLIQAQVKVYRGDPTYILQILRHIQFSCSHIPQQAIQQLATTLSISIPKIRALI
CCHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHH
EFYHFLHYHPRGDYDIYISDSIIDHMSGKNEISNYLCEKLNVKLNQPRADGRVTVSNTSC
HHHHHHHCCCCCCEEEEECHHHHHHCCCHHHHHHHHHHHHCCEECCCCCCCEEEEECCCC
TGMSDQGPAALINGLALTRLTRKKVDQIVTKIEGKIAIDRWPKAWFEVTDNIQSKGVLLN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHCCCCCCEEEE
SESRPGEAIKKALATAPHDSLAEIDKSGLRGCGGAGFKTAEKWKSCLLSDDNQRYVVCNA
CCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEC
DEGEPGTFKDRVLLNSYADLLIEGMTLCAYVIGAQKGFIYLRYEYQHLYKKLLETLQRRR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHH
AANLLGAHILNSELSFDIEIFMGAGSYVCGEESALLESLEGRRAIPRIRPPFPVTHGYLD
HHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
KPTVVNNVETFCYAALIIEKGAENFSAQGLAGFTGCKILSISGDVEKTGIYEIPLGLPVK
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEECCCCCHH
NVLNLCGAQSVQAVQVGGPSGTLITPAEFSRVISFDDLHTGGSFMVFNQSRDILENALNF
HHHHHHCCCCEEEEEECCCCCCEECHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHH
THFFMQESCGFCTPCRVGTKLIYDLADKVATGQGARLDLDSIKQLNHVMNGMSHCGLGQR
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHCCCCHH
AAEPLLETLEKFPEYFVKRMTDIEYQPSFDVEKSIQRAIDIVTIESNS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHEEEEEEECCC
>Mature Secondary Structure
MNKALATLIQAQVKVYRGDPTYILQILRHIQFSCSHIPQQAIQQLATTLSISIPKIRALI
CCHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHH
EFYHFLHYHPRGDYDIYISDSIIDHMSGKNEISNYLCEKLNVKLNQPRADGRVTVSNTSC
HHHHHHHCCCCCCEEEEECHHHHHHCCCHHHHHHHHHHHHCCEECCCCCCCEEEEECCCC
TGMSDQGPAALINGLALTRLTRKKVDQIVTKIEGKIAIDRWPKAWFEVTDNIQSKGVLLN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHCCCCCCEEEE
SESRPGEAIKKALATAPHDSLAEIDKSGLRGCGGAGFKTAEKWKSCLLSDDNQRYVVCNA
CCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEC
DEGEPGTFKDRVLLNSYADLLIEGMTLCAYVIGAQKGFIYLRYEYQHLYKKLLETLQRRR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHH
AANLLGAHILNSELSFDIEIFMGAGSYVCGEESALLESLEGRRAIPRIRPPFPVTHGYLD
HHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
KPTVVNNVETFCYAALIIEKGAENFSAQGLAGFTGCKILSISGDVEKTGIYEIPLGLPVK
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEECCCCCHH
NVLNLCGAQSVQAVQVGGPSGTLITPAEFSRVISFDDLHTGGSFMVFNQSRDILENALNF
HHHHHHCCCCEEEEEECCCCCCEECHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHH
THFFMQESCGFCTPCRVGTKLIYDLADKVATGQGARLDLDSIKQLNHVMNGMSHCGLGQR
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHCCCCHH
AAEPLLETLEKFPEYFVKRMTDIEYQPSFDVEKSIQRAIDIVTIESNS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2188945; 12948488; 2496982 [H]