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The map label for this gene is ligA [H]

Identifier: 119944913

GI number: 119944913

Start: 1448076

End: 1448915

Strand: Reverse

Name: ligA [H]

Synonym: Ping_1157

Alternate gene names: 119944913

Gene position: 1448915-1448076 (Counterclockwise)

Preceding gene: 119944914

Following gene: 119944910

Centisome position: 31.78

GC content: 37.62

Gene sequence:

>840_bases
ATGTCATATAAGATATTATTTTTTCTACTTTGTCTTTTTTCACCTTTATCTCACTCAAACGAAACTTTATCACCTCCGAT
TCAACTTGCTACCCTTTATCATCAAGATATTAATATCCAGGCATATTGGGTAAGCGAGAAATTGGATGGCGTGCGTGCTT
ATTGGGACGGCAAACAACTCATTTCCAAGCAGGGTAATGTTTTTAATGCGCCGGGGTGGTTTATTAAAGATTTCCCACAA
CAGCGATTAGATGGTGAGTTGTGGATTAATCGTCATCAATTTGAACAAGTTTCAGGGATCACGCGAAAACTGCAGCCCAT
TGATCAAGAGTGGCAAAAAATATCTTTTATGATTTTTGACCTGCCTGGCTCTGATGCTGATTTCACATCCCGTTTACAAC
AAATACAAAAATTAATTCAGTCAAGTGACTCAGCCTATCTCAAAATGATTAAACAACAACGAGTTGAAAATAATCAGCAG
CTGCAATTATTATTAGAGCAGGTACTCAATAATGGGGGTGAAGGGTTAATGCTACATAAAGGGGAAGCTTACTATCAGGC
AAAACGCAGTAAAGATTTAATGAAATTAAAAAAATATGAAGATGCTGAGGCGGTTGTTATTCAGTATTTTCCCGGTAAAG
GGAGAAACGCTGGTAGGCTTGGATCATTACTTGTTGAAACAAAAGAGGGAATTAAATTCAAAATTGGTACTGGATTCTCC
GATCTAGAGCGTGAAAACCCACCGCCTATTGGCGCTACAATCACTTATAAATACACTGGAAAAACAAATAATAATGTTCC
CCGTTTTGCCAGCTTTATGCGTATTAGAGACGCTTATTAA

Upstream 100 bases:

>100_bases
GTTATACAAAATAGTTCCCTGCGTCTGATTAGTGACATTGCTATGATTTGTATTTATTAAAAACCGCCCTAAGCTTGTTG
GACTGTTTAGGGAGTTTTTT

Downstream 100 bases:

>100_bases
AGATTAAAGTATTAAAAATTAAACGGGTTACAGTTTTTTTATAATAGCCGCATTAGCATCGGGAAATGAATAAGTAAGTA
ATTCAGCTTTATTAACCCAT

Product: DNA ligase

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MSYKILFFLLCLFSPLSHSNETLSPPIQLATLYHQDINIQAYWVSEKLDGVRAYWDGKQLISKQGNVFNAPGWFIKDFPQ
QRLDGELWINRHQFEQVSGITRKLQPIDQEWQKISFMIFDLPGSDADFTSRLQQIQKLIQSSDSAYLKMIKQQRVENNQQ
LQLLLEQVLNNGGEGLMLHKGEAYYQAKRSKDLMKLKKYEDAEAVVIQYFPGKGRNAGRLGSLLVETKEGIKFKIGTGFS
DLERENPPPIGATITYKYTGKTNNNVPRFASFMRIRDAY

Sequences:

>Translated_279_residues
MSYKILFFLLCLFSPLSHSNETLSPPIQLATLYHQDINIQAYWVSEKLDGVRAYWDGKQLISKQGNVFNAPGWFIKDFPQ
QRLDGELWINRHQFEQVSGITRKLQPIDQEWQKISFMIFDLPGSDADFTSRLQQIQKLIQSSDSAYLKMIKQQRVENNQQ
LQLLLEQVLNNGGEGLMLHKGEAYYQAKRSKDLMKLKKYEDAEAVVIQYFPGKGRNAGRLGSLLVETKEGIKFKIGTGFS
DLERENPPPIGATITYKYTGKTNNNVPRFASFMRIRDAY
>Mature_278_residues
SYKILFFLLCLFSPLSHSNETLSPPIQLATLYHQDINIQAYWVSEKLDGVRAYWDGKQLISKQGNVFNAPGWFIKDFPQQ
RLDGELWINRHQFEQVSGITRKLQPIDQEWQKISFMIFDLPGSDADFTSRLQQIQKLIQSSDSAYLKMIKQQRVENNQQL
QLLLEQVLNNGGEGLMLHKGEAYYQAKRSKDLMKLKKYEDAEAVVIQYFPGKGRNAGRLGSLLVETKEGIKFKIGTGFSD
LERENPPPIGATITYKYTGKTNNNVPRFASFMRIRDAY

Specific function: Catalyzes efficient strand joining on a single nicked DNA [H]

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF01068 DNA_ligase_A_M [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 32154; Mature: 32023

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYKILFFLLCLFSPLSHSNETLSPPIQLATLYHQDINIQAYWVSEKLDGVRAYWDGKQL
CCHHHHHHHHHHHCCCCCCCCCCCCCHHEEEEEECCCCEEEEEECCCCCCHHHHCCHHHH
ISKQGNVFNAPGWFIKDFPQQRLDGELWINRHQFEQVSGITRKLQPIDQEWQKISFMIFD
HHCCCCEECCCCCHHHHCCHHHCCCCEEECHHHHHHHHHHHHHHCCHHHHHHEEEEEEEE
LPGSDADFTSRLQQIQKLIQSSDSAYLKMIKQQRVENNQQLQLLLEQVLNNGGEGLMLHK
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEC
GEAYYQAKRSKDLMKLKKYEDAEAVVIQYFPGKGRNAGRLGSLLVETKEGIKFKIGTGFS
CHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHEECCCCCEEEECCCHH
DLERENPPPIGATITYKYTGKTNNNVPRFASFMRIRDAY
HHHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SYKILFFLLCLFSPLSHSNETLSPPIQLATLYHQDINIQAYWVSEKLDGVRAYWDGKQL
CHHHHHHHHHHHCCCCCCCCCCCCCHHEEEEEECCCCEEEEEECCCCCCHHHHCCHHHH
ISKQGNVFNAPGWFIKDFPQQRLDGELWINRHQFEQVSGITRKLQPIDQEWQKISFMIFD
HHCCCCEECCCCCHHHHCCHHHCCCCEEECHHHHHHHHHHHHHHCCHHHHHHEEEEEEEE
LPGSDADFTSRLQQIQKLIQSSDSAYLKMIKQQRVENNQQLQLLLEQVLNNGGEGLMLHK
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEC
GEAYYQAKRSKDLMKLKKYEDAEAVVIQYFPGKGRNAGRLGSLLVETKEGIKFKIGTGFS
CHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHEECCCCCEEEECCCHH
DLERENPPPIGATITYKYTGKTNNNVPRFASFMRIRDAY
HHHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550458; 7542800; 9060431 [H]