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The map label for this gene is fadD [C]

Identifier: 119944712

GI number: 119944712

Start: 1188796

End: 1191027

Strand: Reverse

Name: fadD [C]

Synonym: Ping_0952

Alternate gene names: 119944712

Gene position: 1191027-1188796 (Counterclockwise)

Preceding gene: 119944713

Following gene: 119944711

Centisome position: 26.12

GC content: 41.85

Gene sequence:

>2232_bases
ATGAAAAGGTTATTAAAAAAAATTGAATATTTCGCACATAACACGCCAAATAACATTGCATTACAAGGCAGTTCAGCACG
TAGCGCCGAATTGGTAGAGTTAACTTATCTGCAATTATGGCAGGAGATTAAAAGGACTGAGCAACAATTGATCGACAATG
ATTGCCAATGTATCGCATTACGCGCGGAAAACAGCATTGATTGGGCAATCATTGATTTAGCCACGCTATTAGCGAAGATC
CCGATTATTCCTATCCCAATGTTTTTTACTGAGCAGCAAGTCAGACATATTTTAAACTCGGTCGGCATTGATACTTTGAT
TGGCGATTGGCCACATATCAGCAACAGCGCATCAATCCCCTTCGCATACCTTAGCGGTTATAAAGTGATCCCCGCTAAAA
ATACTGCCCCCTTATTTACAGGGACAGCCAAAATAACCTTTACGTCTGGTTCAACCGGATCGCCAAAAGGTGTGTGCTTA
AGCCAGGCACATTTAGGGGAGGTGACGCAGTCATTAATCAACACCATCAACGGCGATAATAAACCATTACGTCACTTAGT
ATTATTACCTTTATCGACCTTACTGGAAAACCTGACGGGTATTTATGTGCCGTTACAAATGGGTCTTTGCAGTGTGATCC
ATCCAGGAGAAAAGGTCGGCTTAATGGGTTCAAGTCAATTTGATCCGGCTATTTTCTGCCAGGCGCTAATGACTCATCAA
CCGCACAGCTTAGTATTAACACCGGCTTTATTGCAGGCTTTGATTCAAATAAAAACACGACAACCACAACTGGTCAGTGG
GCTTAAATTTGTTGCGGTAGGCGGCGCCCAAGTTTCAGAAAAAATAATGCAGCGAGCTTTTGCACTTGGTATTCCTGCTT
ATGAAGGTTATGGCTTATCGGAGTGTGGTTCGGTGGTGAGCTTAAACTCTCACATAAATACTAAATTGGGTAGCTGTGGT
CAAGCATTAGGTCATTGCAAAGTAGAGGTTGCCAATGATGGAGAAATACGGGTAACGGGTGCATCTATGCTGGGTTATCT
TGGTCAGGCAGCCAGCGGCACGGTGATTAAAACCGGCGATATTGGTTATCTTGATGAGCACAATTATCTGCATATTACCG
GCCGTAAAAGTAACTTGTTGATCAGCAGTTATGGACGAAATATTTCCCCTGAATGGATTGAATCAGAAGCACGCGCTTAC
CCTGAATTACAGCAGATAGTAGTGATGGGTGATGCACAACAAGCACTAACAGCAGTAATTGATAACTCGCATATTGACCA
GCAAGAGATTATCGCTGCGGTTAAAAAACTAAATAATAGTTTACCCGATTATGCACAAATACACACTCTTATTATTACCC
GACCCTTTGCGGATTATGAGGGATTGGTCACTGCTAATGGCCGCCCTATTCGCGCTAATTTCAATAAAAAATTTACGCCT
GTTATACAACATTCAGAGTCTCAATCGACAACGAACGACCCGACTATGACTCTGATTTCAATTAAGGATAAGACAATGCA
GCAAACAAGTGATTTTTTCAGCGTATTGCAACAAGCAACCGCAAAAGAGCAGCAGGTGATGTACCAGTCACCTATTTTTG
CGGCTTGCCAGCGTGGTGAAATTTCACTGCAAACTTACCATGCCTTTTTAACCCAGGCTTACCATCATGTAAAACAGACG
GTGCCATTGTTAATGGCTTGCGGTTCACGTTTATGTGAAGATTACGAATGGTTACGTTATGCATTGGCACAATATATTGA
AGAAGAAAAAGGCCATCAAGAATGGATCTTAAACGATATCACAGCCTGTGGTTTTGATGCTGAAATAGTGCGTAATAACG
AAGGAGTCGGCAAGATTGGTACGGCTATGGAACTAATGGTGGCTTACCTTTACCATCAAATCGATCGCAAAAACCCATTG
GCATTTCTAGGGATGGTCTGGGTATTGGAAGGCACCAGTGTCAATGTCGGTGGAAAAATAGCTGAATTAGTACAACATAA
GTTGGATTTACCTGATACTGCAATGAGTTACCTCACGTCACACAGTACATTAGATCAAAAGCACATTAAGTTATTTGCTT
CCTTAATGAATAAGATTACCGACAAAAATGACCAACAGGCGATTATTGACGGTGCAAATATGGTCTTCAAACTTTACGGT
GAAATGTTAAACGATCTCTCATCGAATGCTATTGAACAGATTCAGCAAAGCGAGTTCTGCCATGAAGCTTAA

Upstream 100 bases:

>100_bases
CACAGCCCCGTGTATCGGCAGGTAATTTAAAAGCGGGCTTAGCACAATTAATCCAACGTTATGATGAAATCTCTAGCCGC
CAATCGCGAGTGAAAATCTC

Downstream 100 bases:

>100_bases
AGATAAACGCGTGTTATTAACGGGGGCAACAGGCGGTATTGGTCGCGCTCTTTCCCTGGCATTGGTTGAGGCTGGTTGCC
ACTTAATCTTAGTCGGCCGA

Product: long-chain-fatty-acid--CoA ligase

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase; LACS [H]

Number of amino acids: Translated: 743; Mature: 743

Protein sequence:

>743_residues
MKRLLKKIEYFAHNTPNNIALQGSSARSAELVELTYLQLWQEIKRTEQQLIDNDCQCIALRAENSIDWAIIDLATLLAKI
PIIPIPMFFTEQQVRHILNSVGIDTLIGDWPHISNSASIPFAYLSGYKVIPAKNTAPLFTGTAKITFTSGSTGSPKGVCL
SQAHLGEVTQSLINTINGDNKPLRHLVLLPLSTLLENLTGIYVPLQMGLCSVIHPGEKVGLMGSSQFDPAIFCQALMTHQ
PHSLVLTPALLQALIQIKTRQPQLVSGLKFVAVGGAQVSEKIMQRAFALGIPAYEGYGLSECGSVVSLNSHINTKLGSCG
QALGHCKVEVANDGEIRVTGASMLGYLGQAASGTVIKTGDIGYLDEHNYLHITGRKSNLLISSYGRNISPEWIESEARAY
PELQQIVVMGDAQQALTAVIDNSHIDQQEIIAAVKKLNNSLPDYAQIHTLIITRPFADYEGLVTANGRPIRANFNKKFTP
VIQHSESQSTTNDPTMTLISIKDKTMQQTSDFFSVLQQATAKEQQVMYQSPIFAACQRGEISLQTYHAFLTQAYHHVKQT
VPLLMACGSRLCEDYEWLRYALAQYIEEEKGHQEWILNDITACGFDAEIVRNNEGVGKIGTAMELMVAYLYHQIDRKNPL
AFLGMVWVLEGTSVNVGGKIAELVQHKLDLPDTAMSYLTSHSTLDQKHIKLFASLMNKITDKNDQQAIIDGANMVFKLYG
EMLNDLSSNAIEQIQQSEFCHEA

Sequences:

>Translated_743_residues
MKRLLKKIEYFAHNTPNNIALQGSSARSAELVELTYLQLWQEIKRTEQQLIDNDCQCIALRAENSIDWAIIDLATLLAKI
PIIPIPMFFTEQQVRHILNSVGIDTLIGDWPHISNSASIPFAYLSGYKVIPAKNTAPLFTGTAKITFTSGSTGSPKGVCL
SQAHLGEVTQSLINTINGDNKPLRHLVLLPLSTLLENLTGIYVPLQMGLCSVIHPGEKVGLMGSSQFDPAIFCQALMTHQ
PHSLVLTPALLQALIQIKTRQPQLVSGLKFVAVGGAQVSEKIMQRAFALGIPAYEGYGLSECGSVVSLNSHINTKLGSCG
QALGHCKVEVANDGEIRVTGASMLGYLGQAASGTVIKTGDIGYLDEHNYLHITGRKSNLLISSYGRNISPEWIESEARAY
PELQQIVVMGDAQQALTAVIDNSHIDQQEIIAAVKKLNNSLPDYAQIHTLIITRPFADYEGLVTANGRPIRANFNKKFTP
VIQHSESQSTTNDPTMTLISIKDKTMQQTSDFFSVLQQATAKEQQVMYQSPIFAACQRGEISLQTYHAFLTQAYHHVKQT
VPLLMACGSRLCEDYEWLRYALAQYIEEEKGHQEWILNDITACGFDAEIVRNNEGVGKIGTAMELMVAYLYHQIDRKNPL
AFLGMVWVLEGTSVNVGGKIAELVQHKLDLPDTAMSYLTSHSTLDQKHIKLFASLMNKITDKNDQQAIIDGANMVFKLYG
EMLNDLSSNAIEQIQQSEFCHEA
>Mature_743_residues
MKRLLKKIEYFAHNTPNNIALQGSSARSAELVELTYLQLWQEIKRTEQQLIDNDCQCIALRAENSIDWAIIDLATLLAKI
PIIPIPMFFTEQQVRHILNSVGIDTLIGDWPHISNSASIPFAYLSGYKVIPAKNTAPLFTGTAKITFTSGSTGSPKGVCL
SQAHLGEVTQSLINTINGDNKPLRHLVLLPLSTLLENLTGIYVPLQMGLCSVIHPGEKVGLMGSSQFDPAIFCQALMTHQ
PHSLVLTPALLQALIQIKTRQPQLVSGLKFVAVGGAQVSEKIMQRAFALGIPAYEGYGLSECGSVVSLNSHINTKLGSCG
QALGHCKVEVANDGEIRVTGASMLGYLGQAASGTVIKTGDIGYLDEHNYLHITGRKSNLLISSYGRNISPEWIESEARAY
PELQQIVVMGDAQQALTAVIDNSHIDQQEIIAAVKKLNNSLPDYAQIHTLIITRPFADYEGLVTANGRPIRANFNKKFTP
VIQHSESQSTTNDPTMTLISIKDKTMQQTSDFFSVLQQATAKEQQVMYQSPIFAACQRGEISLQTYHAFLTQAYHHVKQT
VPLLMACGSRLCEDYEWLRYALAQYIEEEKGHQEWILNDITACGFDAEIVRNNEGVGKIGTAMELMVAYLYHQIDRKNPL
AFLGMVWVLEGTSVNVGGKIAELVQHKLDLPDTAMSYLTSHSTLDQKHIKLFASLMNKITDKNDQQAIIDGANMVFKLYG
EMLNDLSSNAIEQIQQSEFCHEA

Specific function: Esterification, Concomitant With Transport, Of Exogenous Long-Chain Fatty Acids Into Metabolically Active CoA Thioesters For Subsequent Degradation Or Incorporation Into Phospholipids. [C]

COG id: COG1022

COG function: function code I; Long-chain acyl-CoA synthetases (AMP-forming)

Gene ontology:

Cell location: Partially Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI27477105, Length=335, Percent_Identity=25.3731343283582, Blast_Score=76, Evalue=1e-13,
Organism=Escherichia coli, GI1788107, Length=320, Percent_Identity=26.875, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI145693145, Length=295, Percent_Identity=25.0847457627119, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17558820, Length=361, Percent_Identity=25.4847645429363, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17559526, Length=344, Percent_Identity=25.8720930232558, Blast_Score=73, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI32563687, Length=326, Percent_Identity=23.3128834355828, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24653035, Length=322, Percent_Identity=25.4658385093168, Blast_Score=84, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21356947, Length=331, Percent_Identity=25.9818731117825, Blast_Score=84, Evalue=5e-16,
Organism=Drosophila melanogaster, GI161076582, Length=329, Percent_Identity=25.531914893617, Blast_Score=81, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21356441, Length=323, Percent_Identity=23.8390092879257, Blast_Score=73, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24648257, Length=323, Percent_Identity=23.8390092879257, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281365686, Length=324, Percent_Identity=23.7654320987654, Blast_Score=70, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24648255, Length=333, Percent_Identity=22.5225225225225, Blast_Score=70, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24648253, Length=333, Percent_Identity=22.5225225225225, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI19921316, Length=170, Percent_Identity=31.7647058823529, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 81944; Mature: 81944

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLLKKIEYFAHNTPNNIALQGSSARSAELVELTYLQLWQEIKRTEQQLIDNDCQCIAL
CHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
RAENSIDWAIIDLATLLAKIPIIPIPMFFTEQQVRHILNSVGIDTLIGDWPHISNSASIP
ECCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCC
FAYLSGYKVIPAKNTAPLFTGTAKITFTSGSTGSPKGVCLSQAHLGEVTQSLINTINGDN
CHHHCCEEEEECCCCCCEEECCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHCCCC
KPLRHLVLLPLSTLLENLTGIYVPLQMGLCSVIHPGEKVGLMGSSQFDPAIFCQALMTHQ
CHHHHHHHHHHHHHHHHHCCEEEEHHHCHHHHCCCCCCEECCCCCCCCHHHHHHHHHCCC
PHSLVLTPALLQALIQIKTRQPQLVSGLKFVAVGGAQVSEKIMQRAFALGIPAYEGYGLS
CCCEEECHHHHHHHHHHHCCCCHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCHH
ECGSVVSLNSHINTKLGSCGQALGHCKVEVANDGEIRVTGASMLGYLGQAASGTVIKTGD
HCCCEEEECCHHCCHHHHHHHHHCCEEEEEECCCCEEEEHHHHHHHHCCCCCCCEEECCC
IGYLDEHNYLHITGRKSNLLISSYGRNISPEWIESEARAYPELQQIVVMGDAQQALTAVI
CCEECCCCEEEEECCCCCEEEECCCCCCCHHHHHHHHHHCCCHHHEEEECCHHHHHHHHH
DNSHIDQQEIIAAVKKLNNSLPDYAQIHTLIITRPFADYEGLVTANGRPIRANFNKKFTP
CCCCCCHHHHHHHHHHHHCCCCCHHHHEEEEEECCCCCCCCEEECCCEEEECCCCCCCCH
VIQHSESQSTTNDPTMTLISIKDKTMQQTSDFFSVLQQATAKEQQVMYQSPIFAACQRGE
HHCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCC
ISLQTYHAFLTQAYHHVKQTVPLLMACGSRLCEDYEWLRYALAQYIEEEKGHQEWILNDI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TACGFDAEIVRNNEGVGKIGTAMELMVAYLYHQIDRKNPLAFLGMVWVLEGTSVNVGGKI
HHCCCCHHEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHEEEHHEEECCEECCCHHH
AELVQHKLDLPDTAMSYLTSHSTLDQKHIKLFASLMNKITDKNDQQAIIDGANMVFKLYG
HHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
EMLNDLSSNAIEQIQQSEFCHEA
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRLLKKIEYFAHNTPNNIALQGSSARSAELVELTYLQLWQEIKRTEQQLIDNDCQCIAL
CHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
RAENSIDWAIIDLATLLAKIPIIPIPMFFTEQQVRHILNSVGIDTLIGDWPHISNSASIP
ECCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCC
FAYLSGYKVIPAKNTAPLFTGTAKITFTSGSTGSPKGVCLSQAHLGEVTQSLINTINGDN
CHHHCCEEEEECCCCCCEEECCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHCCCC
KPLRHLVLLPLSTLLENLTGIYVPLQMGLCSVIHPGEKVGLMGSSQFDPAIFCQALMTHQ
CHHHHHHHHHHHHHHHHHCCEEEEHHHCHHHHCCCCCCEECCCCCCCCHHHHHHHHHCCC
PHSLVLTPALLQALIQIKTRQPQLVSGLKFVAVGGAQVSEKIMQRAFALGIPAYEGYGLS
CCCEEECHHHHHHHHHHHCCCCHHHCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCHH
ECGSVVSLNSHINTKLGSCGQALGHCKVEVANDGEIRVTGASMLGYLGQAASGTVIKTGD
HCCCEEEECCHHCCHHHHHHHHHCCEEEEEECCCCEEEEHHHHHHHHCCCCCCCEEECCC
IGYLDEHNYLHITGRKSNLLISSYGRNISPEWIESEARAYPELQQIVVMGDAQQALTAVI
CCEECCCCEEEEECCCCCEEEECCCCCCCHHHHHHHHHHCCCHHHEEEECCHHHHHHHHH
DNSHIDQQEIIAAVKKLNNSLPDYAQIHTLIITRPFADYEGLVTANGRPIRANFNKKFTP
CCCCCCHHHHHHHHHHHHCCCCCHHHHEEEEEECCCCCCCCEEECCCEEEECCCCCCCCH
VIQHSESQSTTNDPTMTLISIKDKTMQQTSDFFSVLQQATAKEQQVMYQSPIFAACQRGE
HHCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCC
ISLQTYHAFLTQAYHHVKQTVPLLMACGSRLCEDYEWLRYALAQYIEEEKGHQEWILNDI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
TACGFDAEIVRNNEGVGKIGTAMELMVAYLYHQIDRKNPLAFLGMVWVLEGTSVNVGGKI
HHCCCCHHEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHEEEHHEEECCEECCCHHH
AELVQHKLDLPDTAMSYLTSHSTLDQKHIKLFASLMNKITDKNDQQAIIDGANMVFKLYG
HHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
EMLNDLSSNAIEQIQQSEFCHEA
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]