Click here to switch to the map view.

The map label for this gene is paaK [H]

Identifier: 119944432

GI number: 119944432

Start: 845466

End: 846761

Strand: Direct

Name: paaK [H]

Synonym: Ping_0660

Alternate gene names: 119944432

Gene position: 845466-846761 (Clockwise)

Preceding gene: 119944431

Following gene: 119944433

Centisome position: 18.54

GC content: 40.97

Gene sequence:

>1296_bases
ATGACAATTTATAATAAATTAGAATCAATTGAAAAAGCATCATCTGAAGATCTGCGTGCTTTACAGTTTGAGCGTATGAA
ATGGACCATTGAACACGCTTATCAAAACTCTCCAATGTATAAGAAAAAATTTGATGATGCCGGCGTACAGCCTTCAGATT
TTCAATGCTTGGAAGACATTAATAAATTTCCTTACACCACCAAAGAAGATCTTCGTCAAAACTATCCCTTTGGTACGCTT
GCAGTCCCAATGAAAGATGTTGTCCGTGTCCATGCATCATCGGGCACAACCGGAAAACCGACCGTTGTCGGCTACACTCA
AAACGATATTGATACCTGGGCAACTATTGTGGCTCGTTCAATTCGAGCGGCAGGCGGTAGTTCAGAAGACATTATCCATA
TTGCTTATGGTTATGGCCTGTTTACCGGAGGGTTGGGGGCACATTATGGTGCTGAAAAACTGGGTGCGACTGTTATTCCA
ATGTCCGGCGGACAAACCGAAAAACAAATTCAATTAATTGAAGATTTTAAACCCACTATTATTATGGTGACGCCTTCTTA
TTGTTTAAATTTGATTGATGAACTTGAGAAAAAACACGGCGGTGATGCCTCAAATTGTTCACTGAAAATTGGTATCTTTG
GCGCCGAGCCTTGGACTGACTCTATGCGCAAAGAAATCGAAAACCGCTTAGGCATTAAAGCGTTAGACATCTACGGTTTA
ACCGAAGTGATGGGCCCTGGGGTTGCAATGGAATGTGCTGAAACAGCCGATGGTCCAACCATTTGGGAAGATCATTTTTA
CCCTGAAATTGTTAATCCTGTTAGTGGTGATGTTCTACCTGATAATGAACATGGTGAATTAGTCTTTACCTCGCTAACAA
AAGAAGCGATGCCTGTTATACGCTATAGAACGCGCGATTTAACCCGGCTTTTACCCGGTACAGCAAGAACAATGCGACGT
ATGGATAAAATAACCGGTCGCAGCGATGATATGTTGATTATCCGCGGCGTAAATGTATTTCCATCACAAGTAGAAGAACA
AATTCTCAGTGTTGCCGGATTCGATCCACATTATCAACTTGAAATTAATAAGCAGGGAAACCTTGATACATTGACAGTCA
AAGTTGAACTCAAAGGCACGATAGACAACCAAACAAGTATTAATATGGTGACTGAACTTAAGCATCGAATCAAAACAATG
ATTGGTGTATCTTCAAAAATATTGATTCAACCTAGTGGCGTTATTCCTCGCTCGGAAGGCAAAGCACAGCGTGTTTTTGA
TTTAAGAGCATCCTAA

Upstream 100 bases:

>100_bases
TCAAGGCATTGCCATGATCATTGAACGCGTTTAATTGCTTATTTAACTCTGTTGTTAGGGCTATAAAAACAGAGTGATAT
ATTAAAAAGGAAAGAGAACA

Downstream 100 bases:

>100_bases
ATATTTTATAAAAAAAAAGCTTCTCCTCTTTATTATTAGTTAATAAATAAAGAATAAAACTAAGTAATGTCTTTAATTTT
ATTCTTTATCATATGAAAGT

Product: phenylacetate-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MTIYNKLESIEKASSEDLRALQFERMKWTIEHAYQNSPMYKKKFDDAGVQPSDFQCLEDINKFPYTTKEDLRQNYPFGTL
AVPMKDVVRVHASSGTTGKPTVVGYTQNDIDTWATIVARSIRAAGGSSEDIIHIAYGYGLFTGGLGAHYGAEKLGATVIP
MSGGQTEKQIQLIEDFKPTIIMVTPSYCLNLIDELEKKHGGDASNCSLKIGIFGAEPWTDSMRKEIENRLGIKALDIYGL
TEVMGPGVAMECAETADGPTIWEDHFYPEIVNPVSGDVLPDNEHGELVFTSLTKEAMPVIRYRTRDLTRLLPGTARTMRR
MDKITGRSDDMLIIRGVNVFPSQVEEQILSVAGFDPHYQLEINKQGNLDTLTVKVELKGTIDNQTSINMVTELKHRIKTM
IGVSSKILIQPSGVIPRSEGKAQRVFDLRAS

Sequences:

>Translated_431_residues
MTIYNKLESIEKASSEDLRALQFERMKWTIEHAYQNSPMYKKKFDDAGVQPSDFQCLEDINKFPYTTKEDLRQNYPFGTL
AVPMKDVVRVHASSGTTGKPTVVGYTQNDIDTWATIVARSIRAAGGSSEDIIHIAYGYGLFTGGLGAHYGAEKLGATVIP
MSGGQTEKQIQLIEDFKPTIIMVTPSYCLNLIDELEKKHGGDASNCSLKIGIFGAEPWTDSMRKEIENRLGIKALDIYGL
TEVMGPGVAMECAETADGPTIWEDHFYPEIVNPVSGDVLPDNEHGELVFTSLTKEAMPVIRYRTRDLTRLLPGTARTMRR
MDKITGRSDDMLIIRGVNVFPSQVEEQILSVAGFDPHYQLEINKQGNLDTLTVKVELKGTIDNQTSINMVTELKHRIKTM
IGVSSKILIQPSGVIPRSEGKAQRVFDLRAS
>Mature_430_residues
TIYNKLESIEKASSEDLRALQFERMKWTIEHAYQNSPMYKKKFDDAGVQPSDFQCLEDINKFPYTTKEDLRQNYPFGTLA
VPMKDVVRVHASSGTTGKPTVVGYTQNDIDTWATIVARSIRAAGGSSEDIIHIAYGYGLFTGGLGAHYGAEKLGATVIPM
SGGQTEKQIQLIEDFKPTIIMVTPSYCLNLIDELEKKHGGDASNCSLKIGIFGAEPWTDSMRKEIENRLGIKALDIYGLT
EVMGPGVAMECAETADGPTIWEDHFYPEIVNPVSGDVLPDNEHGELVFTSLTKEAMPVIRYRTRDLTRLLPGTARTMRRM
DKITGRSDDMLIIRGVNVFPSQVEEQILSVAGFDPHYQLEINKQGNLDTLTVKVELKGTIDNQTSINMVTELKHRIKTMI
GVSSKILIQPSGVIPRSEGKAQRVFDLRAS

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=432, Percent_Identity=72.4537037037037, Blast_Score=672, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 47901; Mature: 47770

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIYNKLESIEKASSEDLRALQFERMKWTIEHAYQNSPMYKKKFDDAGVQPSDFQCLEDI
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCHHHHHHH
NKFPYTTKEDLRQNYPFGTLAVPMKDVVRVHASSGTTGKPTVVGYTQNDIDTWATIVARS
HHCCCCCHHHHHHCCCCCEEECCHHHHHEEECCCCCCCCCEEEEECCCCHHHHHHHHHHH
IRAAGGSSEDIIHIAYGYGLFTGGLGAHYGAEKLGATVIPMSGGQTEKQIQLIEDFKPTI
HHHCCCCCCCEEEEEECCHHHCCCCCCCCCHHHHCCEEEECCCCCCHHHHHHHHCCCCEE
IMVTPSYCLNLIDELEKKHGGDASNCSLKIGIFGAEPWTDSMRKEIENRLGIKALDIYGL
EEECHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCEEEECCCH
TEVMGPGVAMECAETADGPTIWEDHFYPEIVNPVSGDVLPDNEHGELVFTSLTKEAMPVI
HHHHCCCCEEEHHHCCCCCCEECCCCCHHHCCCCCCCCCCCCCCCCEEEEEHHHHHHHHH
RYRTRDLTRLLPGTARTMRRMDKITGRSDDMLIIRGVNVFPSQVEEQILSVAGFDPHYQL
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCEEE
EINKQGNLDTLTVKVELKGTIDNQTSINMVTELKHRIKTMIGVSSKILIQPSGVIPRSEG
EECCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCC
KAQRVFDLRAS
CCEEEEEECCC
>Mature Secondary Structure 
TIYNKLESIEKASSEDLRALQFERMKWTIEHAYQNSPMYKKKFDDAGVQPSDFQCLEDI
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCHHHHHHH
NKFPYTTKEDLRQNYPFGTLAVPMKDVVRVHASSGTTGKPTVVGYTQNDIDTWATIVARS
HHCCCCCHHHHHHCCCCCEEECCHHHHHEEECCCCCCCCCEEEEECCCCHHHHHHHHHHH
IRAAGGSSEDIIHIAYGYGLFTGGLGAHYGAEKLGATVIPMSGGQTEKQIQLIEDFKPTI
HHHCCCCCCCEEEEEECCHHHCCCCCCCCCHHHHCCEEEECCCCCCHHHHHHHHCCCCEE
IMVTPSYCLNLIDELEKKHGGDASNCSLKIGIFGAEPWTDSMRKEIENRLGIKALDIYGL
EEECHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCEEEECCCH
TEVMGPGVAMECAETADGPTIWEDHFYPEIVNPVSGDVLPDNEHGELVFTSLTKEAMPVI
HHHHCCCCEEEHHHCCCCCCEECCCCCHHHCCCCCCCCCCCCCCCCEEEEEHHHHHHHHH
RYRTRDLTRLLPGTARTMRRMDKITGRSDDMLIIRGVNVFPSQVEEQILSVAGFDPHYQL
HHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCEEE
EINKQGNLDTLTVKVELKGTIDNQTSINMVTELKHRIKTMIGVSSKILIQPSGVIPRSEG
EECCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCC
KAQRVFDLRAS
CCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]