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The map label for this gene is paaE [H]

Identifier: 119944426

GI number: 119944426

Start: 839586

End: 840641

Strand: Direct

Name: paaE [H]

Synonym: Ping_0654

Alternate gene names: 119944426

Gene position: 839586-840641 (Clockwise)

Preceding gene: 119944425

Following gene: 119944427

Centisome position: 18.41

GC content: 39.68

Gene sequence:

>1056_bases
ATGACAACATTTTACCCGCTTATGATAAAAGAAATACAACATGAAACGAATGATGCCGTCGTGCTTACATTTGCAATTCC
AGCGTCATTATCAGCAGAGTTTAAATTTAAGCCAGGGCAATACCTGACGCTGAAATCAACGCTTGATAATGAGGAGCTGC
GCCGTTGTTATTCAATATGCTCATCTGCTAACGACAGCGATCTTAGTATTGGCATTAAAGAAATCCCCGATGGGCGCTTT
TCACAATATGCAAATAAAGAATTAAAAGTGGGAGATTCGATTGATGTTATGTCTCCAAAAGGTCAGTTTGGCTTTGAACC
TGAAAAAAACACCAATAAAAAATATTTAGGTATTGCCGTTGGCTCAGGCATTACGCCTATTATTTCGATGTTAAAAAGCA
CCTTAGAAGCCGAGCCTGAAAGTCAATTTACGCTGCTTTATGGTAATAAAACACTGAATTCCACTATGTTCAAAAGAGAA
TTATCCGATTATAAAAATCGCTTTACGGACAGATTGCAGCTTGTTTATTTATTTTCCCGTGAAAGTCATGAGGCTGAACT
GCTAAACGGCCGGCTGGATGCGCAAAAACTTCAAGATTTAGGTCATTCCTTTTTTGATTGGAGTAAATTTAATGAGTGCT
ATCTGTGTGGTCCGGAGGAGATGTTAGAGCCTTCTTACAGCGTTTTAAATAAAGGCGGACTGCGCAAAGAGAACTTTCAT
GTTGAACGCTTTAATATTTCAAAAAGTCCACGACGAGCAATTGAGAGTCATGTTGAAAAAAGCGAGATAACAGTAAAACG
TGATGGCCGTATTATGTCAATTGAAATGACTGAAGATGACGATAGTATTTTAGATGCAGCGCTTCGACAAGGTGCTGATC
TTCCTCACGCATGTAAAGGGGGCGTCTGTGCAACCTGCATTTGTAAAGTGACATCGGGTACCGTTGAGATGTCGGTTAAT
TATAGTTTGGAAGATGAACAAGTTAATAAAGGTTTTGTTCTTAGCTGCCAGGCTGTACCGACTTCAAATGCAGTCACCGT
TGACTTTGATGCTTAG

Upstream 100 bases:

>100_bases
ATCAGTGAGTTTGGATCAACAGCCTGTAAAGCACATTATAAATGCCTTACTTGTTATGAACCTTTTGATTACTTTAAATG
TATTTAATCGAGAACTAATT

Downstream 100 bases:

>100_bases
GAGGCAGGGATATTGACTTTAAATAATGAATCAAATTTTCTTCAATGCTCTGAAAAAAAGGGTGTGCTGTTAATACAATT
TACGCATTACGAAAAACGTA

Product: phenylacetate-CoA oxygenase/reductase, PaaK subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MTTFYPLMIKEIQHETNDAVVLTFAIPASLSAEFKFKPGQYLTLKSTLDNEELRRCYSICSSANDSDLSIGIKEIPDGRF
SQYANKELKVGDSIDVMSPKGQFGFEPEKNTNKKYLGIAVGSGITPIISMLKSTLEAEPESQFTLLYGNKTLNSTMFKRE
LSDYKNRFTDRLQLVYLFSRESHEAELLNGRLDAQKLQDLGHSFFDWSKFNECYLCGPEEMLEPSYSVLNKGGLRKENFH
VERFNISKSPRRAIESHVEKSEITVKRDGRIMSIEMTEDDDSILDAALRQGADLPHACKGGVCATCICKVTSGTVEMSVN
YSLEDEQVNKGFVLSCQAVPTSNAVTVDFDA

Sequences:

>Translated_351_residues
MTTFYPLMIKEIQHETNDAVVLTFAIPASLSAEFKFKPGQYLTLKSTLDNEELRRCYSICSSANDSDLSIGIKEIPDGRF
SQYANKELKVGDSIDVMSPKGQFGFEPEKNTNKKYLGIAVGSGITPIISMLKSTLEAEPESQFTLLYGNKTLNSTMFKRE
LSDYKNRFTDRLQLVYLFSRESHEAELLNGRLDAQKLQDLGHSFFDWSKFNECYLCGPEEMLEPSYSVLNKGGLRKENFH
VERFNISKSPRRAIESHVEKSEITVKRDGRIMSIEMTEDDDSILDAALRQGADLPHACKGGVCATCICKVTSGTVEMSVN
YSLEDEQVNKGFVLSCQAVPTSNAVTVDFDA
>Mature_350_residues
TTFYPLMIKEIQHETNDAVVLTFAIPASLSAEFKFKPGQYLTLKSTLDNEELRRCYSICSSANDSDLSIGIKEIPDGRFS
QYANKELKVGDSIDVMSPKGQFGFEPEKNTNKKYLGIAVGSGITPIISMLKSTLEAEPESQFTLLYGNKTLNSTMFKREL
SDYKNRFTDRLQLVYLFSRESHEAELLNGRLDAQKLQDLGHSFFDWSKFNECYLCGPEEMLEPSYSVLNKGGLRKENFHV
ERFNISKSPRRAIESHVEKSEITVKRDGRIMSIEMTEDDDSILDAALRQGADLPHACKGGVCATCICKVTSGTVEMSVNY
SLEDEQVNKGFVLSCQAVPTSNAVTVDFDA

Specific function: May be part of a multicomponent oxygenase involved in phenylacetyl-CoA hydroxylation [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI284448553, Length=245, Percent_Identity=24.8979591836735, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI6552328, Length=245, Percent_Identity=24.8979591836735, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI193794826, Length=245, Percent_Identity=24.8979591836735, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI284448551, Length=245, Percent_Identity=24.8979591836735, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI4503327, Length=245, Percent_Identity=25.3061224489796, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1787658, Length=352, Percent_Identity=48.2954545454545, Blast_Score=386, Evalue=1e-108,
Organism=Escherichia coli, GI1787098, Length=345, Percent_Identity=23.4782608695652, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788903, Length=240, Percent_Identity=25.8333333333333, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788104, Length=320, Percent_Identity=22.5, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323510, Length=186, Percent_Identity=27.9569892473118, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322146, Length=183, Percent_Identity=24.5901639344262, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR011884
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39329; Mature: 39198

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFYPLMIKEIQHETNDAVVLTFAIPASLSAEFKFKPGQYLTLKSTLDNEELRRCYSIC
CCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHH
SSANDSDLSIGIKEIPDGRFSQYANKELKVGDSIDVMSPKGQFGFEPEKNTNKKYLGIAV
CCCCCCCEEEEHHHCCCCHHHHHCCCCEECCCCEECCCCCCCCCCCCCCCCCCEEEEEEE
GSGITPIISMLKSTLEAEPESQFTLLYGNKTLNSTMFKRELSDYKNRFTDRLQLVYLFSR
CCCHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECC
ESHEAELLNGRLDAQKLQDLGHSFFDWSKFNECYLCGPEEMLEPSYSVLNKGGLRKENFH
CCCHHHHHCCCCCHHHHHHCCCHHHCHHHCCCEEEECCHHHHCCCHHHHHCCCCCCCCEE
VERFNISKSPRRAIESHVEKSEITVKRDGRIMSIEMTEDDDSILDAALRQGADLPHACKG
EEEECCCCCHHHHHHHHCCHHCEEEEECCEEEEEEECCCCHHHHHHHHHCCCCCCCHHCC
GVCATCICKVTSGTVEMSVNYSLEDEQVNKGFVLSCQAVPTSNAVTVDFDA
CHHEEEEEEECCCEEEEEEEECCCCCCCCCCEEEEEEECCCCCCEEEEECC
>Mature Secondary Structure 
TTFYPLMIKEIQHETNDAVVLTFAIPASLSAEFKFKPGQYLTLKSTLDNEELRRCYSIC
CCCHHHHHHHHHCCCCCEEEEEEEECCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHH
SSANDSDLSIGIKEIPDGRFSQYANKELKVGDSIDVMSPKGQFGFEPEKNTNKKYLGIAV
CCCCCCCEEEEHHHCCCCHHHHHCCCCEECCCCEECCCCCCCCCCCCCCCCCCEEEEEEE
GSGITPIISMLKSTLEAEPESQFTLLYGNKTLNSTMFKRELSDYKNRFTDRLQLVYLFSR
CCCHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECC
ESHEAELLNGRLDAQKLQDLGHSFFDWSKFNECYLCGPEEMLEPSYSVLNKGGLRKENFH
CCCHHHHHCCCCCHHHHHHCCCHHHCHHHCCCEEEECCHHHHCCCHHHHHCCCCCCCCEE
VERFNISKSPRRAIESHVEKSEITVKRDGRIMSIEMTEDDDSILDAALRQGADLPHACKG
EEEECCCCCHHHHHHHHCCHHCEEEEECCEEEEEEECCCCHHHHHHHHHCCCCCCCHHCC
GVCATCICKVTSGTVEMSVNYSLEDEQVNKGFVLSCQAVPTSNAVTVDFDA
CHHEEEEEEECCCEEEEEEEECCCCCCCCCCEEEEEEECCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD [C]

Metal ions: Iron-Sulfur [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]