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The map label for this gene is era [H]

Identifier: 119944413

GI number: 119944413

Start: 826093

End: 826995

Strand: Direct

Name: era [H]

Synonym: Ping_0641

Alternate gene names: 119944413

Gene position: 826093-826995 (Clockwise)

Preceding gene: 119944412

Following gene: 119944414

Centisome position: 18.12

GC content: 40.2

Gene sequence:

>903_bases
ATGACTCAAAAATGTGGATTAGTGGCAATAGTGGGTCGTCCTAACGTAGGTAAATCAACCCTTATTAATGCTCTTTTAGG
GCAAAAAGTAAGTATTACGTCGCGTAAAGCGCAAACCACCCGTCACCGTATTTTAGGTATTGATACCGAGGGGGATTACC
AAACTATCTTTGTTGATACGCCAGGGCTTCATATCGAAGAGAAACGTGCGATTAACCGCTTAATGAACCGCGCAGCATCA
AGCTCAATCAATGATGTTGAAATGGTCATTTTTGTTGTTGAAGGCACACATTGGAATGAAGATGACGACATGGTACTGAG
TAAGTTTAAGTACTTAAAATGTCCGGTTGTTTTAGCGGTTAATAAGATTGATAACGTCGAAGACAAAGAATTATTACTGC
CACATTTAGAAGCACTGGGTAAACGTTATAACTTTAAACATATTTTACCTATGTCGGCTAAAAAGGGCGATAATATAGAA
AAAATTCGGACCTGGGCAAAAGAAGTGCTGCCAGAATCGGAGCATTATTTTCCCGAAGACTACATCACGGACCGTTCCTC
ACGCTTTATGGCATCAGAAATGGTCCGTGAAAAATTAATGCGTTTTCTAGGTGATGAACTGCCTTATTCTGTCACGGTAG
AAATCGAGCAGTTTAAGCAGCAGGCCAATGGTGTTTTACACATTAATGCCTTGATCTTGGTCGAACGGGAAGGTCAAAAA
CGCATGGTTATCGGTAATAAAGGTGAAAAACTGAAAGCCATAGGTAAACAAGCGCGTATTGATATGGAAGAATTATTTGA
TTCAAAAGTCTTTCTGGAAATTTGGGTCAAAGTTAAATCAGGTTGGGCTGATGATGATCGCGCCCTGCGCAGTTTAGGTT
ATGGTGATGATTATTTAGGTTAG

Upstream 100 bases:

>100_bases
GCTAAATAATGATCCAGAAATGTGAATGTGCTGCACTGGCAGAACGTCTTGAAATATTAATAGAAATCAATGTTGAATTT
CTAATGTTGGGAGAAAAATA

Downstream 100 bases:

>100_bases
TCAGGTGAAAGGCTGTCAGCTTTTAGCCTTCTGCCGACAGCCGATAGCTGATAGCTGATAGCCGACAGCTGATAGCCGAC
AGCTGATAGCCGACAGCTGA

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTQKCGLVAIVGRPNVGKSTLINALLGQKVSITSRKAQTTRHRILGIDTEGDYQTIFVDTPGLHIEEKRAINRLMNRAAS
SSINDVEMVIFVVEGTHWNEDDDMVLSKFKYLKCPVVLAVNKIDNVEDKELLLPHLEALGKRYNFKHILPMSAKKGDNIE
KIRTWAKEVLPESEHYFPEDYITDRSSRFMASEMVREKLMRFLGDELPYSVTVEIEQFKQQANGVLHINALILVEREGQK
RMVIGNKGEKLKAIGKQARIDMEELFDSKVFLEIWVKVKSGWADDDRALRSLGYGDDYLG

Sequences:

>Translated_300_residues
MTQKCGLVAIVGRPNVGKSTLINALLGQKVSITSRKAQTTRHRILGIDTEGDYQTIFVDTPGLHIEEKRAINRLMNRAAS
SSINDVEMVIFVVEGTHWNEDDDMVLSKFKYLKCPVVLAVNKIDNVEDKELLLPHLEALGKRYNFKHILPMSAKKGDNIE
KIRTWAKEVLPESEHYFPEDYITDRSSRFMASEMVREKLMRFLGDELPYSVTVEIEQFKQQANGVLHINALILVEREGQK
RMVIGNKGEKLKAIGKQARIDMEELFDSKVFLEIWVKVKSGWADDDRALRSLGYGDDYLG
>Mature_299_residues
TQKCGLVAIVGRPNVGKSTLINALLGQKVSITSRKAQTTRHRILGIDTEGDYQTIFVDTPGLHIEEKRAINRLMNRAASS
SINDVEMVIFVVEGTHWNEDDDMVLSKFKYLKCPVVLAVNKIDNVEDKELLLPHLEALGKRYNFKHILPMSAKKGDNIEK
IRTWAKEVLPESEHYFPEDYITDRSSRFMASEMVREKLMRFLGDELPYSVTVEIEQFKQQANGVLHINALILVEREGQKR
MVIGNKGEKLKAIGKQARIDMEELFDSKVFLEIWVKVKSGWADDDRALRSLGYGDDYLG

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=320, Percent_Identity=27.1875, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI1788919, Length=293, Percent_Identity=70.6484641638225, Blast_Score=433, Evalue=1e-123,
Organism=Saccharomyces cerevisiae, GI6323665, Length=234, Percent_Identity=26.4957264957265, Blast_Score=62, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24646434, Length=307, Percent_Identity=28.0130293159609, Blast_Score=110, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34212; Mature: 34081

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKCGLVAIVGRPNVGKSTLINALLGQKVSITSRKAQTTRHRILGIDTEGDYQTIFVDT
CCCCCCEEEEECCCCCCHHHHHHHHHCCCEEECHHHHHHHHHEEEEECCCCCEEEEEEEC
PGLHIEEKRAINRLMNRAASSSINDVEMVIFVVEGTHWNEDDDMVLSKFKYLKCPVVLAV
CCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEE
NKIDNVEDKELLLPHLEALGKRYNFKHILPMSAKKGDNIEKIRTWAKEVLPESEHYFPED
CCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCHH
YITDRSSRFMASEMVREKLMRFLGDELPYSVTVEIEQFKQQANGVLHINALILVEREGQK
HHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHCCCEEEEEEEEEEEECCCE
RMVIGNKGEKLKAIGKQARIDMEELFDSKVFLEIWVKVKSGWADDDRALRSLGYGDDYLG
EEEECCCCCHHHHHHHHHCCCHHHHHCCCEEEEEEEEHHCCCCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TQKCGLVAIVGRPNVGKSTLINALLGQKVSITSRKAQTTRHRILGIDTEGDYQTIFVDT
CCCCCEEEEECCCCCCHHHHHHHHHCCCEEECHHHHHHHHHEEEEECCCCCEEEEEEEC
PGLHIEEKRAINRLMNRAASSSINDVEMVIFVVEGTHWNEDDDMVLSKFKYLKCPVVLAV
CCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEE
NKIDNVEDKELLLPHLEALGKRYNFKHILPMSAKKGDNIEKIRTWAKEVLPESEHYFPED
CCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCCCCHH
YITDRSSRFMASEMVREKLMRFLGDELPYSVTVEIEQFKQQANGVLHINALILVEREGQK
HHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHCCCEEEEEEEEEEEECCCE
RMVIGNKGEKLKAIGKQARIDMEELFDSKVFLEIWVKVKSGWADDDRALRSLGYGDDYLG
EEEECCCCCHHHHHHHHHCCCHHHHHCCCEEEEEEEEHHCCCCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA