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The map label for this gene is corC [H]

Identifier: 119944305

GI number: 119944305

Start: 680746

End: 681606

Strand: Reverse

Name: corC [H]

Synonym: Ping_0532

Alternate gene names: 119944305

Gene position: 681606-680746 (Counterclockwise)

Preceding gene: 119944306

Following gene: 119944304

Centisome position: 14.95

GC content: 40.19

Gene sequence:

>861_bases
ATGCCCGACGATAAAGCACAAACATCATCAGATAAAATAGGACTATTCGATAAAATTAGTAATCTTTTCCAGGGCGAGCC
ACAAACTCAACAAGAATTACTGGATGTGATTCAAGGTGCTAAATCGCGCCAGATTATCGATCAACAAACCCGAGAGATGA
TTAAAGGCGTTTTAGATGTATCAAAATTACGTGTCCGTGACATTATGATCCCGCGTTCACAAATGACCACCTTAGGTCTG
CATCAAAGCGTCAATGAATTCCTGCCGAAAATTATCGATTCCGCACATTCTCGCTTTCCGGTGATAACCGAAGATAAAGA
CCATATAGTCGGTCTTTTGCTGGCCAAGGATTTGATTAGATTTGGTTTCAGCAGTGAAGCAAATGAGTTTAAAATTGAAG
ATATACTCAGGGAAGCCGTCGTTGTTCCTGAAAGTAAACGCTTAGGAACTTTATTAAAAGAGTTTCGCAGTCAACGCTAC
CACATGGCGATTGTCGTTGATGAGTACGGTGGCGTATCAGGGCTGGTGACCATCGAAGATATTTTAGAAGTGATAGTGGG
TGAAATTGAAGATGAATTTGACGATCAAGAAGAGGATGATATCCGTCAGATTGGTAAAAGAACTTATGTGGTTAATGCCA
TGACATCCATTGAGAAGTTTAATAACTTTTTTTCCACCTCATTTGATATTGAAGGACAAGATACCGTTGCTGGTTTTATT
ATCCATGAATTAGGCCACCTTCCCCGCCGCGGTGAAAGGATCACTATTGATGAGCATCAATTCAAAGTCACTATTAGTGA
AAAACGCCGCTTAATACAACTGCAGGTACTGATTCCTAAAGAATTAAGCAGTATTGAGTGA

Upstream 100 bases:

>100_bases
GCAAGCCGAAGCAGTTGAAATGGAAAGTTTAGAGACAAAACTGTTAACCGAACTTGGTTTTACAGACCCTTACTTAAGTG
AAAAAGAGTAAATAAAATTA

Downstream 100 bases:

>100_bases
TCCTGTTTTGATTAAAAAAATAGATAATTTAACCAAGCACCTTTATGGACAACTTTTTGTTGCCTGTATTTTAGGTGCCG
TTCAGGTTTTTGCTTTTGCC

Product: Mg2+/Co2+ transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MPDDKAQTSSDKIGLFDKISNLFQGEPQTQQELLDVIQGAKSRQIIDQQTREMIKGVLDVSKLRVRDIMIPRSQMTTLGL
HQSVNEFLPKIIDSAHSRFPVITEDKDHIVGLLLAKDLIRFGFSSEANEFKIEDILREAVVVPESKRLGTLLKEFRSQRY
HMAIVVDEYGGVSGLVTIEDILEVIVGEIEDEFDDQEEDDIRQIGKRTYVVNAMTSIEKFNNFFSTSFDIEGQDTVAGFI
IHELGHLPRRGERITIDEHQFKVTISEKRRLIQLQVLIPKELSSIE

Sequences:

>Translated_286_residues
MPDDKAQTSSDKIGLFDKISNLFQGEPQTQQELLDVIQGAKSRQIIDQQTREMIKGVLDVSKLRVRDIMIPRSQMTTLGL
HQSVNEFLPKIIDSAHSRFPVITEDKDHIVGLLLAKDLIRFGFSSEANEFKIEDILREAVVVPESKRLGTLLKEFRSQRY
HMAIVVDEYGGVSGLVTIEDILEVIVGEIEDEFDDQEEDDIRQIGKRTYVVNAMTSIEKFNNFFSTSFDIEGQDTVAGFI
IHELGHLPRRGERITIDEHQFKVTISEKRRLIQLQVLIPKELSSIE
>Mature_285_residues
PDDKAQTSSDKIGLFDKISNLFQGEPQTQQELLDVIQGAKSRQIIDQQTREMIKGVLDVSKLRVRDIMIPRSQMTTLGLH
QSVNEFLPKIIDSAHSRFPVITEDKDHIVGLLLAKDLIRFGFSSEANEFKIEDILREAVVVPESKRLGTLLKEFRSQRYH
MAIVVDEYGGVSGLVTIEDILEVIVGEIEDEFDDQEEDDIRQIGKRTYVVNAMTSIEKFNNFFSTSFDIEGQDTVAGFII
HELGHLPRRGERITIDEHQFKVTISEKRRLIQLQVLIPKELSSIE

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=219, Percent_Identity=31.9634703196347, Blast_Score=122, Evalue=3e-28,
Organism=Escherichia coli, GI1786879, Length=285, Percent_Identity=55.7894736842105, Blast_Score=295, Evalue=2e-81,
Organism=Escherichia coli, GI145693175, Length=257, Percent_Identity=28.0155642023346, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI87082033, Length=240, Percent_Identity=26.6666666666667, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790664, Length=250, Percent_Identity=23.2, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1788119, Length=223, Percent_Identity=31.390134529148, Blast_Score=89, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 32653; Mature: 32522

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDDKAQTSSDKIGLFDKISNLFQGEPQTQQELLDVIQGAKSRQIIDQQTREMIKGVLDV
CCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
SKLRVRDIMIPRSQMTTLGLHQSVNEFLPKIIDSAHSRFPVITEDKDHIVGLLLAKDLIR
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHH
FGFSSEANEFKIEDILREAVVVPESKRLGTLLKEFRSQRYHMAIVVDEYGGVSGLVTIED
HCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEHHH
ILEVIVGEIEDEFDDQEEDDIRQIGKRTYVVNAMTSIEKFNNFFSTSFDIEGQDTVAGFI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
IHELGHLPRRGERITIDEHQFKVTISEKRRLIQLQVLIPKELSSIE
HHHHCCCCCCCCEEEEECCEEEEEEHHCCCEEEEEEECCHHHCCCC
>Mature Secondary Structure 
PDDKAQTSSDKIGLFDKISNLFQGEPQTQQELLDVIQGAKSRQIIDQQTREMIKGVLDV
CCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
SKLRVRDIMIPRSQMTTLGLHQSVNEFLPKIIDSAHSRFPVITEDKDHIVGLLLAKDLIR
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHH
FGFSSEANEFKIEDILREAVVVPESKRLGTLLKEFRSQRYHMAIVVDEYGGVSGLVTIED
HCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEHHH
ILEVIVGEIEDEFDDQEEDDIRQIGKRTYVVNAMTSIEKFNNFFSTSFDIEGQDTVAGFI
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
IHELGHLPRRGERITIDEHQFKVTISEKRRLIQLQVLIPKELSSIE
HHHHCCCCCCCCEEEEECCEEEEEEHHCCCEEEEEEECCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]