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The map label for this gene is treA [H]

Identifier: 119944296

GI number: 119944296

Start: 666467

End: 668149

Strand: Direct

Name: treA [H]

Synonym: Ping_0523

Alternate gene names: 119944296

Gene position: 666467-668149 (Clockwise)

Preceding gene: 119944295

Following gene: 119944298

Centisome position: 14.62

GC content: 41.53

Gene sequence:

>1683_bases
ATGAATAAAATAGAAAGAGAATGGTGGCGCACAGCGACGGTGTATCAGATTTATCCTAAAAGCTTTTGTGACAGCGGCAG
TAAAGGTACGGGGGATCTTAAAGGTATTATCTCTAAACTGGATTATCTTAAAACTCTGGGTATTGATGCCATTTGGCTTA
CCCCGATTTATGCATCACCGATGATTGATAATGGTTATGATATCTCAGATTATTACACTATTAATCCTGATTTTGGTTGT
ATGGAGGATTTTGAGCAGCTCCTGGACAGTGCTCATCAGAAAGGTATCCGCATTATTTTAGATATTGTGGTTAATCATAC
TTCAACTGAGCATCAATGGTTCCAATCGGCTTTGGGTAATAAAGACAGTGAATATCGGGATTATTATATCTGGAAAGACC
CTGTAAATGGTCAGGCGCCGAACAATTGGGTATCAAAATTTGGCGGTAATGCCTGGCAGTTAGATGAAAAAACTCAGCAA
TACTACCTGCACCTTTTTGCCCCGGAGCAGGCTGATTTAAACTGGGAAAATCCCAAAGTGCGTGATCAAGTCAAAAACAT
CATCGAGTTTTGGGCTGAAAAAGGAGTTGATGGTTTTCGTCTTGATGTGATTAACTTAATCTCTAAACAGCAGGATTATG
CAAATGACTATCAGGGCGATGGTCGCCGTTTCTACACCGATGGACCACGCGTGCATCAATACCTGCGCGAGTTAAGTGAT
GCTGTGTTTAATCAATATGGTGCAGTCACGGTCGGCGAAATGTCTTCTACTTCACTCGATGAGTGCCAGCAATATTCAGC
ACTTGACGGAAAAGAGTTATCTATGGTGTTTAATTTTCACCATTTAAAAGTTGATTATATAAACGGTGAAAAATGGACGC
AGGCACCCTTTGATTTTATAGAGCTGAAAACTATTTTTAATCATTGGCAGCAGGGCATGTTCGGGAAAGGATGGTCTGCA
CTATTCTGGTGTAATCATGATCAGCCGCGAATAGTTAGCCGTTTAGGTAATGATCAAGAATATCGCGTTGAATCCGCGAA
GATGCTGGCAACATCACTGCATATGATGCAGGGCACACCTTATATTTATCAGGGTGAAGAGATTGCCATGACCAATCCTG
GTTATACATCAATTGAACAATACCGCGATCTTGAAAGCCTTAATATGTACGATATTATGCTCAATCATCAGGGGAAAAGT
GAGCAGCAGGTGCTGGCTATTCTTGCCCAGAAATCGCGAGATAATTCGCGCACACCCATTCAGTGGAACAGTGATCAGAA
TGCCGGTTTTACAAAAGGTGTTCCCTGGCTGGATGTGGCAAAGAATTATAAGCAGATTAATGTCGAGCGGGCGCTTAAGG
ATCAAAACTCGGTTTTTTATTATTACCAGCATTTAATCGCGCTGCGTAAAGAAGTGGAGGTAATAACAACCGGGGATTAT
ACGGATTTGGCAGCGGAGCATGCACAACTGTTTTGTTATCAACGGCGCAGTGACAAGCAAACGCTTATCTGTATCAATAA
CTATTACGGGAAGCCGCTTGAATATGAATTGCCAGCACATCTGGAACTGCACAACGGACAATATATTATTGGAAATTACC
CGGAATTATTAACCCTTCAACCAACGAGGACAGTAAAATTAAAACCCTATGAGAGTCGAGTATTGCTGATTAACCATCAT
TAA

Upstream 100 bases:

>100_bases
AATGTTAATGAATTAAAACTGTCTGGCGTATTGAAAAAAGATATTAGCCGTTGAGTGATCAACGGTTTTCTTAATTTAAG
AGAGCTAAGAGTTAATAGAT

Downstream 100 bases:

>100_bases
CTTAAGGTTTTACCGATAGTAAGAAAAAGCCTTTAATAGTTTGCTGTTAAAGGCTTTTTAAAATTTAAGATTTTCGATCC
GCAGCAATATAAGCTAAGGT

Product: trehalose-6-phosphate hydrolase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 560; Mature: 560

Protein sequence:

>560_residues
MNKIEREWWRTATVYQIYPKSFCDSGSKGTGDLKGIISKLDYLKTLGIDAIWLTPIYASPMIDNGYDISDYYTINPDFGC
MEDFEQLLDSAHQKGIRIILDIVVNHTSTEHQWFQSALGNKDSEYRDYYIWKDPVNGQAPNNWVSKFGGNAWQLDEKTQQ
YYLHLFAPEQADLNWENPKVRDQVKNIIEFWAEKGVDGFRLDVINLISKQQDYANDYQGDGRRFYTDGPRVHQYLRELSD
AVFNQYGAVTVGEMSSTSLDECQQYSALDGKELSMVFNFHHLKVDYINGEKWTQAPFDFIELKTIFNHWQQGMFGKGWSA
LFWCNHDQPRIVSRLGNDQEYRVESAKMLATSLHMMQGTPYIYQGEEIAMTNPGYTSIEQYRDLESLNMYDIMLNHQGKS
EQQVLAILAQKSRDNSRTPIQWNSDQNAGFTKGVPWLDVAKNYKQINVERALKDQNSVFYYYQHLIALRKEVEVITTGDY
TDLAAEHAQLFCYQRRSDKQTLICINNYYGKPLEYELPAHLELHNGQYIIGNYPELLTLQPTRTVKLKPYESRVLLINHH

Sequences:

>Translated_560_residues
MNKIEREWWRTATVYQIYPKSFCDSGSKGTGDLKGIISKLDYLKTLGIDAIWLTPIYASPMIDNGYDISDYYTINPDFGC
MEDFEQLLDSAHQKGIRIILDIVVNHTSTEHQWFQSALGNKDSEYRDYYIWKDPVNGQAPNNWVSKFGGNAWQLDEKTQQ
YYLHLFAPEQADLNWENPKVRDQVKNIIEFWAEKGVDGFRLDVINLISKQQDYANDYQGDGRRFYTDGPRVHQYLRELSD
AVFNQYGAVTVGEMSSTSLDECQQYSALDGKELSMVFNFHHLKVDYINGEKWTQAPFDFIELKTIFNHWQQGMFGKGWSA
LFWCNHDQPRIVSRLGNDQEYRVESAKMLATSLHMMQGTPYIYQGEEIAMTNPGYTSIEQYRDLESLNMYDIMLNHQGKS
EQQVLAILAQKSRDNSRTPIQWNSDQNAGFTKGVPWLDVAKNYKQINVERALKDQNSVFYYYQHLIALRKEVEVITTGDY
TDLAAEHAQLFCYQRRSDKQTLICINNYYGKPLEYELPAHLELHNGQYIIGNYPELLTLQPTRTVKLKPYESRVLLINHH
>Mature_560_residues
MNKIEREWWRTATVYQIYPKSFCDSGSKGTGDLKGIISKLDYLKTLGIDAIWLTPIYASPMIDNGYDISDYYTINPDFGC
MEDFEQLLDSAHQKGIRIILDIVVNHTSTEHQWFQSALGNKDSEYRDYYIWKDPVNGQAPNNWVSKFGGNAWQLDEKTQQ
YYLHLFAPEQADLNWENPKVRDQVKNIIEFWAEKGVDGFRLDVINLISKQQDYANDYQGDGRRFYTDGPRVHQYLRELSD
AVFNQYGAVTVGEMSSTSLDECQQYSALDGKELSMVFNFHHLKVDYINGEKWTQAPFDFIELKTIFNHWQQGMFGKGWSA
LFWCNHDQPRIVSRLGNDQEYRVESAKMLATSLHMMQGTPYIYQGEEIAMTNPGYTSIEQYRDLESLNMYDIMLNHQGKS
EQQVLAILAQKSRDNSRTPIQWNSDQNAGFTKGVPWLDVAKNYKQINVERALKDQNSVFYYYQHLIALRKEVEVITTGDY
TDLAAEHAQLFCYQRRSDKQTLICINNYYGKPLEYELPAHLELHNGQYIIGNYPELLTLQPTRTVKLKPYESRVLLINHH

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=545, Percent_Identity=30.0917431192661, Blast_Score=247, Evalue=3e-65,
Organism=Homo sapiens, GI61744481, Length=122, Percent_Identity=33.6065573770492, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI65506891, Length=123, Percent_Identity=34.1463414634146, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI61744479, Length=122, Percent_Identity=33.6065573770492, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI61744483, Length=122, Percent_Identity=33.6065573770492, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI61744475, Length=123, Percent_Identity=34.1463414634146, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI61744477, Length=123, Percent_Identity=34.1463414634146, Blast_Score=75, Evalue=2e-13,
Organism=Escherichia coli, GI1790687, Length=545, Percent_Identity=58.5321100917431, Blast_Score=666, Evalue=0.0,
Organism=Escherichia coli, GI1786604, Length=197, Percent_Identity=29.9492385786802, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1789995, Length=112, Percent_Identity=33.9285714285714, Blast_Score=70, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25147709, Length=550, Percent_Identity=22.5454545454545, Blast_Score=118, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI32565753, Length=208, Percent_Identity=28.3653846153846, Blast_Score=105, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6322245, Length=582, Percent_Identity=36.7697594501718, Blast_Score=374, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6321726, Length=583, Percent_Identity=35.6775300171527, Blast_Score=365, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6324416, Length=583, Percent_Identity=35.8490566037736, Blast_Score=360, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6322241, Length=583, Percent_Identity=35.8490566037736, Blast_Score=360, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6322021, Length=583, Percent_Identity=35.8490566037736, Blast_Score=360, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6321731, Length=586, Percent_Identity=36.8600682593857, Blast_Score=352, Evalue=1e-97,
Organism=Saccharomyces cerevisiae, GI6319776, Length=586, Percent_Identity=36.6894197952218, Blast_Score=351, Evalue=2e-97,
Organism=Drosophila melanogaster, GI24586593, Length=536, Percent_Identity=35.4477611940299, Blast_Score=293, Evalue=3e-79,
Organism=Drosophila melanogaster, GI24586597, Length=553, Percent_Identity=34.3580470162749, Blast_Score=284, Evalue=9e-77,
Organism=Drosophila melanogaster, GI24586599, Length=538, Percent_Identity=34.2007434944238, Blast_Score=284, Evalue=1e-76,
Organism=Drosophila melanogaster, GI221330053, Length=600, Percent_Identity=33.5, Blast_Score=282, Evalue=5e-76,
Organism=Drosophila melanogaster, GI24583749, Length=546, Percent_Identity=34.0659340659341, Blast_Score=276, Evalue=3e-74,
Organism=Drosophila melanogaster, GI24583747, Length=546, Percent_Identity=34.0659340659341, Blast_Score=276, Evalue=3e-74,
Organism=Drosophila melanogaster, GI24586591, Length=498, Percent_Identity=35.7429718875502, Blast_Score=271, Evalue=1e-72,
Organism=Drosophila melanogaster, GI24586589, Length=535, Percent_Identity=36.4485981308411, Blast_Score=270, Evalue=2e-72,
Organism=Drosophila melanogaster, GI45549022, Length=501, Percent_Identity=35.3293413173653, Blast_Score=269, Evalue=3e-72,
Organism=Drosophila melanogaster, GI24583745, Length=587, Percent_Identity=32.3679727427598, Blast_Score=268, Evalue=9e-72,
Organism=Drosophila melanogaster, GI24586587, Length=489, Percent_Identity=32.1063394683027, Blast_Score=251, Evalue=1e-66,
Organism=Drosophila melanogaster, GI281360393, Length=482, Percent_Identity=32.5726141078838, Blast_Score=221, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 65235; Mature: 65235

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIEREWWRTATVYQIYPKSFCDSGSKGTGDLKGIISKLDYLKTLGIDAIWLTPIYASP
CCCHHHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCEECCC
MIDNGYDISDYYTINPDFGCMEDFEQLLDSAHQKGIRIILDIVVNHTSTEHQWFQSALGN
CCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEHHCCCCHHHHHHHHHHCC
KDSEYRDYYIWKDPVNGQAPNNWVSKFGGNAWQLDEKTQQYYLHLFAPEQADLNWENPKV
CCCCCCCEEEEECCCCCCCCCHHHHHHCCCEEECCCCCCEEEEEEECCCCCCCCCCCCHH
RDQVKNIIEFWAEKGVDGFRLDVINLISKQQDYANDYQGDGRRFYTDGPRVHQYLRELSD
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHH
AVFNQYGAVTVGEMSSTSLDECQQYSALDGKELSMVFNFHHLKVDYINGEKWTQAPFDFI
HHHHHCCCEEECCCCCCCHHHHHHHHCCCCCEEEEEEEEEEEEEEEECCCCCCCCCHHHH
ELKTIFNHWQQGMFGKGWSALFWCNHDQPRIVSRLGNDQEYRVESAKMLATSLHMMQGTP
HHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
YIYQGEEIAMTNPGYTSIEQYRDLESLNMYDIMLNHQGKSEQQVLAILAQKSRDNSRTPI
EEEECCEEEECCCCCHHHHHHHCHHHCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCE
QWNSDQNAGFTKGVPWLDVAKNYKQINVERALKDQNSVFYYYQHLIALRKEVEVITTGDY
EECCCCCCCCCCCCCHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEECCCH
TDLAAEHAQLFCYQRRSDKQTLICINNYYGKPLEYELPAHLELHNGQYIIGNYPELLTLQ
HHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEECCCCEEEECCCEEEECCCCCEEEEC
PTRTVKLKPYESRVLLINHH
CCCEEEECCCCCEEEEEECC
>Mature Secondary Structure
MNKIEREWWRTATVYQIYPKSFCDSGSKGTGDLKGIISKLDYLKTLGIDAIWLTPIYASP
CCCHHHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCEECCC
MIDNGYDISDYYTINPDFGCMEDFEQLLDSAHQKGIRIILDIVVNHTSTEHQWFQSALGN
CCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEHHCCCCHHHHHHHHHHCC
KDSEYRDYYIWKDPVNGQAPNNWVSKFGGNAWQLDEKTQQYYLHLFAPEQADLNWENPKV
CCCCCCCEEEEECCCCCCCCCHHHHHHCCCEEECCCCCCEEEEEEECCCCCCCCCCCCHH
RDQVKNIIEFWAEKGVDGFRLDVINLISKQQDYANDYQGDGRRFYTDGPRVHQYLRELSD
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHHHHH
AVFNQYGAVTVGEMSSTSLDECQQYSALDGKELSMVFNFHHLKVDYINGEKWTQAPFDFI
HHHHHCCCEEECCCCCCCHHHHHHHHCCCCCEEEEEEEEEEEEEEEECCCCCCCCCHHHH
ELKTIFNHWQQGMFGKGWSALFWCNHDQPRIVSRLGNDQEYRVESAKMLATSLHMMQGTP
HHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
YIYQGEEIAMTNPGYTSIEQYRDLESLNMYDIMLNHQGKSEQQVLAILAQKSRDNSRTPI
EEEECCEEEECCCCCHHHHHHHCHHHCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCE
QWNSDQNAGFTKGVPWLDVAKNYKQINVERALKDQNSVFYYYQHLIALRKEVEVITTGDY
EECCCCCCCCCCCCCHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCEEEECCCH
TDLAAEHAQLFCYQRRSDKQTLICINNYYGKPLEYELPAHLELHNGQYIIGNYPELLTLQ
HHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEECCCCEEEECCCEEEECCCCCEEEEC
PTRTVKLKPYESRVLLINHH
CCCEEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7651129; 8969503; 9384377; 7751281 [H]