Click here to switch to the map view.

The map label for this gene is treB [H]

Identifier: 119944295

GI number: 119944295

Start: 664871

End: 666331

Strand: Direct

Name: treB [H]

Synonym: Ping_0522

Alternate gene names: 119944295

Gene position: 664871-666331 (Clockwise)

Preceding gene: 119944294

Following gene: 119944296

Centisome position: 14.58

GC content: 43.6

Gene sequence:

>1461_bases
ATGAGTAAAATTGATCAGAAACAAGTTGAACGTTTAGTTGAGCTTATCGGGGGGAAGGGCAATATAGCCAGTGTTAGCCA
TTGTTTAACACGTTTACGTTTTGCCTTAGGTGATCCTGAATTAGCAAATATTAAAGAAATTGAAAAAATTCCGATGGTAA
AAGGGGCGTTTACTACTGCGGGGCAGTTTCAGATAGTGATTGGTACTGAAGTTGATGACGTATATAAAATATTAACCAAG
ATAACAGGTGGCGGTGGGGCTGATAAAGAAGCGACAAAAGCGGCTGCAAGGCAGAATATGAATTTTCTGGAGCGCGGTAT
CTCGCATATGGCGGAAATTTTTGTCCCGCTGCTCCCTGCTATTATTACTGGCGGTTTGATTCTCGGATTCCGAAATGTGA
TCGGTGATATCCCAATGTTCGATGGTAAAACCCTGGTTGAAACCAGTCAGTTTTGGACTGGAGTTCACTCTTTCCTATGG
TTACTTGGCGAGGCTATCTTCCACTTCCTGCCCGTTGGTGTGTGTTGGGCCACGGTAAAAAAACTGGGCGGTACACCGAT
TCTAGGTATTGTCTTAGGTATCACTCTGGTTTCACCACAATTAATGAATGCTTACGGCATTGGTTCTGGCACACCAGATG
TTTGGGACTTTGGTTTCTTTGTGATGGAAAAAGTGGGCTACCAAGCGCAAGTTATTCCCGCTATTTTAGCCGGTCTGGCT
TTAGCTATTATTGAAACGAATTTAAAACGTATTATTCCCGCCTATTTATACCTTGTTATTGTGCCTTTTGTTTCATTGCT
TGTTGCTGTTGTTTTGGCGCATTCGATTATAGGTCCGATCGGACGTGAAATTGGTAATGCCGTGGGTTATGCCGCTAAAG
TTGCCATGACGGGTGATTTTGCTGTGCTTGGTTCGATGATTTTTGGTTTCTTTTATGCACCCTTAGTGATTACCGGTATT
CACCATACAACCAATGCGGTTGATTTACAGTTAATGCAGGATATTGGCGGAACACCTATCTGGCCACTGATTGCCTTATC
TAATATTGCACAAGCGTCAGCTGTGGTGGGTATTATCTGGATCAGTAAAAAACATAATGAACGTGAGATTTCGATACCTG
CTGCTATCTCTGCATTTTTAGGGGTGACTGAACCCGCTATGTACGGGATCAACTTGAAATATAAATTTCCCATGTTATGC
GCCATGATTGGCTCTGCGGTTGCCGCTGGTATTTGTGGTATTGCAGGTGTGATGGCGAACGGGATTGGTGTCGGTGGATT
GCCGGGTATTCTATCCATTCAGCCGCAGTATTGGGGCGTCTATGCACTGGCGATGCTTACTGCAATAGTGGTACCTATTG
CTTTAACACTGATACTTTACAAACGTGCAGAGAAAAAGGGCAATCTTGACCAAGATGAGTTAATTGAAGACGAGGCAGAA
CCTGCATTAGCCACTCATTAA

Upstream 100 bases:

>100_bases
CGTAATCAAGCCGTCTCCATTTAATTATTTTTTGTTTGCGTTATTATGCCTGCAATTGGGAGCGCTCCCATAAAAGACTT
ATAACAGAAGGGATAATGAA

Downstream 100 bases:

>100_bases
CTGACTATCAAAAAAAGATACGCTGAAATTTTTTTAATGTTAATGAATTAAAACTGTCTGGCGTATTGAAAAAAGATATT
AGCCGTTGAGTGATCAACGG

Product: PTS system trehalose(maltose)-specific transporter subunits IIBC

Products: NA

Alternate protein names: EIIBC-Tre; EII-Tre; Trehalose-specific phosphotransferase enzyme IIB component; PTS system trehalose-specific EIIB component; Trehalose permease IIC component; PTS system trehalose-specific EIIC component [H]

Number of amino acids: Translated: 486; Mature: 485

Protein sequence:

>486_residues
MSKIDQKQVERLVELIGGKGNIASVSHCLTRLRFALGDPELANIKEIEKIPMVKGAFTTAGQFQIVIGTEVDDVYKILTK
ITGGGGADKEATKAAARQNMNFLERGISHMAEIFVPLLPAIITGGLILGFRNVIGDIPMFDGKTLVETSQFWTGVHSFLW
LLGEAIFHFLPVGVCWATVKKLGGTPILGIVLGITLVSPQLMNAYGIGSGTPDVWDFGFFVMEKVGYQAQVIPAILAGLA
LAIIETNLKRIIPAYLYLVIVPFVSLLVAVVLAHSIIGPIGREIGNAVGYAAKVAMTGDFAVLGSMIFGFFYAPLVITGI
HHTTNAVDLQLMQDIGGTPIWPLIALSNIAQASAVVGIIWISKKHNEREISIPAAISAFLGVTEPAMYGINLKYKFPMLC
AMIGSAVAAGICGIAGVMANGIGVGGLPGILSIQPQYWGVYALAMLTAIVVPIALTLILYKRAEKKGNLDQDELIEDEAE
PALATH

Sequences:

>Translated_486_residues
MSKIDQKQVERLVELIGGKGNIASVSHCLTRLRFALGDPELANIKEIEKIPMVKGAFTTAGQFQIVIGTEVDDVYKILTK
ITGGGGADKEATKAAARQNMNFLERGISHMAEIFVPLLPAIITGGLILGFRNVIGDIPMFDGKTLVETSQFWTGVHSFLW
LLGEAIFHFLPVGVCWATVKKLGGTPILGIVLGITLVSPQLMNAYGIGSGTPDVWDFGFFVMEKVGYQAQVIPAILAGLA
LAIIETNLKRIIPAYLYLVIVPFVSLLVAVVLAHSIIGPIGREIGNAVGYAAKVAMTGDFAVLGSMIFGFFYAPLVITGI
HHTTNAVDLQLMQDIGGTPIWPLIALSNIAQASAVVGIIWISKKHNEREISIPAAISAFLGVTEPAMYGINLKYKFPMLC
AMIGSAVAAGICGIAGVMANGIGVGGLPGILSIQPQYWGVYALAMLTAIVVPIALTLILYKRAEKKGNLDQDELIEDEAE
PALATH
>Mature_485_residues
SKIDQKQVERLVELIGGKGNIASVSHCLTRLRFALGDPELANIKEIEKIPMVKGAFTTAGQFQIVIGTEVDDVYKILTKI
TGGGGADKEATKAAARQNMNFLERGISHMAEIFVPLLPAIITGGLILGFRNVIGDIPMFDGKTLVETSQFWTGVHSFLWL
LGEAIFHFLPVGVCWATVKKLGGTPILGIVLGITLVSPQLMNAYGIGSGTPDVWDFGFFVMEKVGYQAQVIPAILAGLAL
AIIETNLKRIIPAYLYLVIVPFVSLLVAVVLAHSIIGPIGREIGNAVGYAAKVAMTGDFAVLGSMIFGFFYAPLVITGIH
HTTNAVDLQLMQDIGGTPIWPLIALSNIAQASAVVGIIWISKKHNEREISIPAAISAFLGVTEPAMYGINLKYKFPMLCA
MIGSAVAAGICGIAGVMANGIGVGGLPGILSIQPQYWGVYALAMLTAIVVPIALTLILYKRAEKKGNLDQDELIEDEAEP
ALATH

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI2367362, Length=470, Percent_Identity=67.2340425531915, Blast_Score=638, Evalue=0.0,
Organism=Escherichia coli, GI1790159, Length=427, Percent_Identity=27.4004683840749, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI48994906, Length=432, Percent_Identity=26.1574074074074, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1788769, Length=418, Percent_Identity=25.3588516746411, Blast_Score=115, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011296 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 51761; Mature: 51630

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIDQKQVERLVELIGGKGNIASVSHCLTRLRFALGDPELANIKEIEKIPMVKGAFTTA
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCC
GQFQIVIGTEVDDVYKILTKITGGGGADKEATKAAARQNMNFLERGISHMAEIFVPLLPA
CEEEEEEECCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
IITGGLILGFRNVIGDIPMFDGKTLVETSQFWTGVHSFLWLLGEAIFHFLPVGVCWATVK
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLGGTPILGIVLGITLVSPQLMNAYGIGSGTPDVWDFGFFVMEKVGYQAQVIPAILAGLA
HHCCCHHHHHHHHHHHHCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
LAIIETNLKRIIPAYLYLVIVPFVSLLVAVVLAHSIIGPIGREIGNAVGYAAKVAMTGDF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHH
AVLGSMIFGFFYAPLVITGIHHTTNAVDLQLMQDIGGTPIWPLIALSNIAQASAVVGIIW
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHEEEEE
ISKKHNEREISIPAAISAFLGVTEPAMYGINLKYKFPMLCAMIGSAVAAGICGIAGVMAN
EECCCCCCEEEHHHHHHHHHCCCCCHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHC
GIGVGGLPGILSIQPQYWGVYALAMLTAIVVPIALTLILYKRAEKKGNLDQDELIEDEAE
CCCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCC
PALATH
CCCCCC
>Mature Secondary Structure 
SKIDQKQVERLVELIGGKGNIASVSHCLTRLRFALGDPELANIKEIEKIPMVKGAFTTA
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCC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CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7608078; 7610040; 9278503 [H]