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The map label for this gene is wecB [H]

Identifier: 119944210

GI number: 119944210

Start: 545606

End: 546790

Strand: Reverse

Name: wecB [H]

Synonym: Ping_0431

Alternate gene names: 119944210

Gene position: 546790-545606 (Counterclockwise)

Preceding gene: 119944212

Following gene: 119944209

Centisome position: 11.99

GC content: 40.76

Gene sequence:

>1185_bases
ATGGTTATGTCTATTAAAATATTAACTGTCTTTGGTACTCGACCTGAAGCAATCAAAATGGCTCCACTTGTCGATGCGCT
AAAAAAACAGCCGGGTATTGACGCTAAAGTTTGCGTTACAGCACAACATAGAGAGATGCTTGACCAGGTACTTAACCTGT
TTGCAATCACCCCCGACTATGATCTTAATATAATGAAGCCAGGGCAGTCTTTATCCGATGTAACCACTAATATTTTATTA
GGGCTTGAACCTATTCTAAAAGAATTTAAGCCCCACCTTATCTTAGTGCACGGTGATACCTCAACGACATTATCGACCAG
TTTAGCCGCATTTTATCAGCAGATTCCAATTGGCCATGTTGAAGCAGGTTTACGTACTGGCGATCTGAACTCTCCTTGGC
CAGAAGAAGGGAATCGCCGACTTACCAGCGCTATTACTAAACTTCATTTTGCCCCAACCGAAAGTGCGAAAGAAAATTTA
CTTAGAGAGTGGATCTCCGCTGATAGCATTGAAGTAACCGGCAATACCGTTATTGATGCTTTGATGCAGGTGATCTATAA
ATTAAAAAACAACACACAACTTTCAAATACATTAGCCAAGCAGTTCCCCCAATTAGATGCCAATAAAAAGCTCATCTTAG
TAACAGGTCATCGCAGAGAAAATTTTGGTAGTGGATTTGAGCGAATTTGTGAGGCGCTGGCAGAAATTGCAAGAAGACAT
TCAAATGTCCAGATAATCTACCCTGTGCATCTAAACCCCAATGTCCGTGAACCGGTTAATCGGATTTTACGCAATCTTGA
CAATATCCATTTAATAGAGCCGCAAGATTACCTTCCTTTTGTTTATTTAATGGATAAAGCGCACATTATTTTAACTGATT
CTGGTGGCATTCAAGAAGAAGCACCAAGTTTAGGCAAACCCGTACTGGTGATGCGAGATGTCACCGAGCGACCTGAAGCG
CTTTCCGCAGGAACGGTTCAACTGGTTGGTACGGACAAAAATAATATTATCAATGCCGTTGAAAAATTACTTCAAGATGA
AATAACTTATAACCGTATGAGTCGTGCACATAACCCCTATGGAGATGGGCAGTCTTGTCAGAAAATAATCAATAGAATCA
TGCATTATTTTGTTACACAAAAGGTGGAAGCAGTCACTGCGGCTTCAGAGCCTATTACAGTTTAG

Upstream 100 bases:

>100_bases
GAACTAACATAATTTATGTAGTTTTAATTTAGGTTAAACAATTTATTACATTTTTAAAATTATTTTTTCCATCTTTAGAT
TTTACAGCTCATACGGAAAT

Downstream 100 bases:

>100_bases
TTTAACAAAAACACTTAATAGATAAATACAAGGCTACAGGGAGTTATCATGGATTTTGAAAAAGTATCCGTCATCGGGCT
TGGCTATATCGGCCTGCCTA

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MVMSIKILTVFGTRPEAIKMAPLVDALKKQPGIDAKVCVTAQHREMLDQVLNLFAITPDYDLNIMKPGQSLSDVTTNILL
GLEPILKEFKPHLILVHGDTSTTLSTSLAAFYQQIPIGHVEAGLRTGDLNSPWPEEGNRRLTSAITKLHFAPTESAKENL
LREWISADSIEVTGNTVIDALMQVIYKLKNNTQLSNTLAKQFPQLDANKKLILVTGHRRENFGSGFERICEALAEIARRH
SNVQIIYPVHLNPNVREPVNRILRNLDNIHLIEPQDYLPFVYLMDKAHIILTDSGGIQEEAPSLGKPVLVMRDVTERPEA
LSAGTVQLVGTDKNNIINAVEKLLQDEITYNRMSRAHNPYGDGQSCQKIINRIMHYFVTQKVEAVTAASEPITV

Sequences:

>Translated_394_residues
MVMSIKILTVFGTRPEAIKMAPLVDALKKQPGIDAKVCVTAQHREMLDQVLNLFAITPDYDLNIMKPGQSLSDVTTNILL
GLEPILKEFKPHLILVHGDTSTTLSTSLAAFYQQIPIGHVEAGLRTGDLNSPWPEEGNRRLTSAITKLHFAPTESAKENL
LREWISADSIEVTGNTVIDALMQVIYKLKNNTQLSNTLAKQFPQLDANKKLILVTGHRRENFGSGFERICEALAEIARRH
SNVQIIYPVHLNPNVREPVNRILRNLDNIHLIEPQDYLPFVYLMDKAHIILTDSGGIQEEAPSLGKPVLVMRDVTERPEA
LSAGTVQLVGTDKNNIINAVEKLLQDEITYNRMSRAHNPYGDGQSCQKIINRIMHYFVTQKVEAVTAASEPITV
>Mature_394_residues
MVMSIKILTVFGTRPEAIKMAPLVDALKKQPGIDAKVCVTAQHREMLDQVLNLFAITPDYDLNIMKPGQSLSDVTTNILL
GLEPILKEFKPHLILVHGDTSTTLSTSLAAFYQQIPIGHVEAGLRTGDLNSPWPEEGNRRLTSAITKLHFAPTESAKENL
LREWISADSIEVTGNTVIDALMQVIYKLKNNTQLSNTLAKQFPQLDANKKLILVTGHRRENFGSGFERICEALAEIARRH
SNVQIIYPVHLNPNVREPVNRILRNLDNIHLIEPQDYLPFVYLMDKAHIILTDSGGIQEEAPSLGKPVLVMRDVTERPEA
LSAGTVQLVGTDKNNIINAVEKLLQDEITYNRMSRAHNPYGDGQSCQKIINRIMHYFVTQKVEAVTAASEPITV

Specific function: Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues [H]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=366, Percent_Identity=68.3060109289617, Blast_Score=516, Evalue=1e-147,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 43945; Mature: 43945

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMSIKILTVFGTRPEAIKMAPLVDALKKQPGIDAKVCVTAQHREMLDQVLNLFAITPDY
CEEEEEEEEEECCCCCCEEHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHEECCCCC
DLNIMKPGQSLSDVTTNILLGLEPILKEFKPHLILVHGDTSTTLSTSLAAFYQQIPIGHV
CCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCHH
EAGLRTGDLNSPWPEEGNRRLTSAITKLHFAPTESAKENLLREWISADSIEVTGNTVIDA
HCCCEECCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEECCHHHHHH
LMQVIYKLKNNTQLSNTLAKQFPQLDANKKLILVTGHRRENFGSGFERICEALAEIARRH
HHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHC
SNVQIIYPVHLNPNVREPVNRILRNLDNIHLIEPQDYLPFVYLMDKAHIILTDSGGIQEE
CCEEEEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCEEEEECCCCCCCC
APSLGKPVLVMRDVTERPEALSAGTVQLVGTDKNNIINAVEKLLQDEITYNRMSRAHNPY
CCCCCCCEEEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
GDGQSCQKIINRIMHYFVTQKVEAVTAASEPITV
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVMSIKILTVFGTRPEAIKMAPLVDALKKQPGIDAKVCVTAQHREMLDQVLNLFAITPDY
CEEEEEEEEEECCCCCCEEHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHEECCCCC
DLNIMKPGQSLSDVTTNILLGLEPILKEFKPHLILVHGDTSTTLSTSLAAFYQQIPIGHV
CCEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHCCCCHH
EAGLRTGDLNSPWPEEGNRRLTSAITKLHFAPTESAKENLLREWISADSIEVTGNTVIDA
HCCCEECCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEECCHHHHHH
LMQVIYKLKNNTQLSNTLAKQFPQLDANKKLILVTGHRRENFGSGFERICEALAEIARRH
HHHHHHHHHCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHC
SNVQIIYPVHLNPNVREPVNRILRNLDNIHLIEPQDYLPFVYLMDKAHIILTDSGGIQEE
CCEEEEEEEECCCCHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCEEEEECCCCCCCC
APSLGKPVLVMRDVTERPEALSAGTVQLVGTDKNNIINAVEKLLQDEITYNRMSRAHNPY
CCCCCCCEEEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
GDGQSCQKIINRIMHYFVTQKVEAVTAASEPITV
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]