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The map label for this gene is glnM [H]

Identifier: 119944193

GI number: 119944193

Start: 525055

End: 525708

Strand: Reverse

Name: glnM [H]

Synonym: Ping_0413

Alternate gene names: 119944193

Gene position: 525708-525055 (Counterclockwise)

Preceding gene: 119944194

Following gene: 119944192

Centisome position: 11.53

GC content: 42.81

Gene sequence:

>654_bases
ATGGACCAGTGGCAGATTATTTGGGAAGCTCGAGAGCTGATTTCTTCTGGACTAATGAATACCTTGTATCTGGTTCTGAT
TAGCATGGCTCTGAGCATCCCTCTGGGAGCTTTAGCCGCAATCGTAGTCATTGAATCTCCCGGATGGCGTAAAATTTTCC
AAGAATTTTTTGACCTACTACGTTGCGTGCCATTTTTATTGCTAGCCTATGTGATGTACTACGGTTTACCTTCTTTGGGA
GTGCGCCTGAGCCCTTGGGAATCAGGGATTGTTACACTGGTTCTGTATAATATGGCTTACTTCGTAGAAATATTCGTCAC
GGCTTATAAAGCTATCAGTCGTGCCGACGTAGAAGCAGCGGATGCCTATGGTTTTTCGTCATTGCAAAAATACAGGCACG
TTATTTTTCCTCAAATTGTGCTGATATCAGCTCCATTGGTTGGCAATCAGATCATTACAGCAATGCGCGACAGTGCCCTG
CTTATGATTATTACTGTTCAGGAACTCACTTTCGCTGCGAATTTTATTAGTGTTAATCACTTTATCCCCTTTCTACCTTT
TGTTGTCGCTGTTGCGCTTTATACGCTGATAACTTTAGTGGTTGAGAGGGGGGTTGCAAGTATATCTAATGTAAGGAAAC
GTTGTTATGGATGA

Upstream 100 bases:

>100_bases
TTATGGCAATGATTCTTTATACCTTGTTTGTTGTCATAATCGTAAAAAGTCAGCGTTTACTTGAGAAAAAAATGACGAAA
AAGTACAAAGGAGGTAAATA

Downstream 100 bases:

>100_bases
TCAATCTATTGTCATTTCGGTAAAAAACCTCAATAAAGACTTCGACGGCGTAGAAGTGCTCAGGGATATCAATATTGATA
TCCTCTCGGGTACGACAACC

Product: ABC polar amino acid transporter inner membrane protein

Products: ADP; phosphate; L-histidine [Cytoplasm]; ADP; L-ornithine [Cytoplasm]; L-arginine [Cytoplasm]; L-lysine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MDQWQIIWEARELISSGLMNTLYLVLISMALSIPLGALAAIVVIESPGWRKIFQEFFDLLRCVPFLLLAYVMYYGLPSLG
VRLSPWESGIVTLVLYNMAYFVEIFVTAYKAISRADVEAADAYGFSSLQKYRHVIFPQIVLISAPLVGNQIITAMRDSAL
LMIITVQELTFAANFISVNHFIPFLPFVVAVALYTLITLVVERGVASISNVRKRCYG

Sequences:

>Translated_217_residues
MDQWQIIWEARELISSGLMNTLYLVLISMALSIPLGALAAIVVIESPGWRKIFQEFFDLLRCVPFLLLAYVMYYGLPSLG
VRLSPWESGIVTLVLYNMAYFVEIFVTAYKAISRADVEAADAYGFSSLQKYRHVIFPQIVLISAPLVGNQIITAMRDSAL
LMIITVQELTFAANFISVNHFIPFLPFVVAVALYTLITLVVERGVASISNVRKRCYG
>Mature_217_residues
MDQWQIIWEARELISSGLMNTLYLVLISMALSIPLGALAAIVVIESPGWRKIFQEFFDLLRCVPFLLLAYVMYYGLPSLG
VRLSPWESGIVTLVLYNMAYFVEIFVTAYKAISRADVEAADAYGFSSLQKYRHVIFPQIVLISAPLVGNQIITAMRDSAL
LMIITVQELTFAANFISVNHFIPFLPFVVAVALYTLITLVVERGVASISNVRKRCYG

Specific function: Part of the ABC transporter complex glnHMPQ involved in glutamine transport. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788646, Length=200, Percent_Identity=28, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787030, Length=204, Percent_Identity=28.4313725490196, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788226, Length=199, Percent_Identity=27.6381909547739, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1788645, Length=202, Percent_Identity=29.2079207920792, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787087, Length=220, Percent_Identity=25, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24341; Mature: 24341

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQWQIIWEARELISSGLMNTLYLVLISMALSIPLGALAAIVVIESPGWRKIFQEFFDLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHH
RCVPFLLLAYVMYYGLPSLGVRLSPWESGIVTLVLYNMAYFVEIFVTAYKAISRADVEAA
HHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
DAYGFSSLQKYRHVIFPQIVLISAPLVGNQIITAMRDSALLMIITVQELTFAANFISVNH
HHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHH
FIPFLPFVVAVALYTLITLVVERGVASISNVRKRCYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDQWQIIWEARELISSGLMNTLYLVLISMALSIPLGALAAIVVIESPGWRKIFQEFFDLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHH
RCVPFLLLAYVMYYGLPSLGVRLSPWESGIVTLVLYNMAYFVEIFVTAYKAISRADVEAA
HHHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
DAYGFSSLQKYRHVIFPQIVLISAPLVGNQIITAMRDSALLMIITVQELTFAANFISVNH
HHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHH
FIPFLPFVVAVALYTLITLVVERGVASISNVRKRCYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-histidine [Periplasm]; H2O; ATP; L-ornithine [Periplasm]; L-arginine [Periplasm]; L-lysine [Periplasm] [C]

Specific reaction: ATP + L-histidine [Periplasm] + H2O = ADP + phosphate + L-histidine [Cytoplasm] ATP + L-ornithine [Periplasm] + H2O = ADP + phosphate + L-ornithine [Cytoplasm] ATP + L-arginine [Periplasm] + H2O = ADP + phosphate + L-arginine [Cytoplasm] ATP + L-lysine [P

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 9384377 [H]