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The map label for this gene is ycbL [H]

Identifier: 119944001

GI number: 119944001

Start: 269538

End: 270185

Strand: Reverse

Name: ycbL [H]

Synonym: Ping_0215

Alternate gene names: 119944001

Gene position: 270185-269538 (Counterclockwise)

Preceding gene: 119944002

Following gene: 119944000

Centisome position: 5.93

GC content: 41.2

Gene sequence:

>648_bases
ATGAGTAATAACAGCATGAAAATTATAGTTATACCCGTTACTCCCTATCAGCAAAACTGCAGTCTGATTATTTGTGAGGA
AACAAAAATTGCCGCCATCGTTGATCCCGGGGGCGATCCGTTGCGTATTTTAAATATTGTTGAAAAACAAGGTGTTAAAG
TTGATAAAATTATATTAACTCATGGTCATTTAGACCATGTCGGTGGCACTCAGGCCGTTGCTGGCAAATTGAATGTACCA
GTGATCGGCCCAGAAAAAGAAGATCTATTCTGGTTAGAGCAATTAGAAGCGCAAAGTCGGCGTTTTGGTTTACCCACAAC
GGAAAGTTTTTCTCCAAACCGATGGTTGACAGAAGGAGAAGTGCTGGAAGTCGGTAAAATAAAACTAAAAGTACTGCGTA
TACCAGGCCATACACCTGGCCATATTGCCCTGTATGATAAGCAAAGCAAACAGGTTATTGTTGGTGATATCTTATTCAAC
GGCGGCATTGGTCGTTTTGATTTCCCGCGTGGTAATCGCTCCTTACTTGTCAGTGGCATTAAAGAAAAATTATTAACACT
ACCGCCTGAAACAACGGTTTATCCGGGGCATGGACCCACTACTACTATTGGCAAAGAGAAAGCAAGCAATCCTTTTTTAC
GTTTGTAA

Upstream 100 bases:

>100_bases
TGAGAATGCCGTCATAAGAACCATTAAGTAGTTTGGGTATATAGTTTCAGATGATTTGCGAATTCATAAGGTAACCAATG
GGTTGCCTTTTTTTATTTCT

Downstream 100 bases:

>100_bases
ATGATGGTGATAATCTTTTAAGCCTGTCTCTTTATAAAATATTGGTTTGCAAAATATTTCTTTTTTAAATCAGGCAATTT
CTATTTTTCACTTCGTAAGT

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MSNNSMKIIVIPVTPYQQNCSLIICEETKIAAIVDPGGDPLRILNIVEKQGVKVDKIILTHGHLDHVGGTQAVAGKLNVP
VIGPEKEDLFWLEQLEAQSRRFGLPTTESFSPNRWLTEGEVLEVGKIKLKVLRIPGHTPGHIALYDKQSKQVIVGDILFN
GGIGRFDFPRGNRSLLVSGIKEKLLTLPPETTVYPGHGPTTTIGKEKASNPFLRL

Sequences:

>Translated_215_residues
MSNNSMKIIVIPVTPYQQNCSLIICEETKIAAIVDPGGDPLRILNIVEKQGVKVDKIILTHGHLDHVGGTQAVAGKLNVP
VIGPEKEDLFWLEQLEAQSRRFGLPTTESFSPNRWLTEGEVLEVGKIKLKVLRIPGHTPGHIALYDKQSKQVIVGDILFN
GGIGRFDFPRGNRSLLVSGIKEKLLTLPPETTVYPGHGPTTTIGKEKASNPFLRL
>Mature_214_residues
SNNSMKIIVIPVTPYQQNCSLIICEETKIAAIVDPGGDPLRILNIVEKQGVKVDKIILTHGHLDHVGGTQAVAGKLNVPV
IGPEKEDLFWLEQLEAQSRRFGLPTTESFSPNRWLTEGEVLEVGKIKLKVLRIPGHTPGHIALYDKQSKQVIVGDILFNG
GIGRFDFPRGNRSLLVSGIKEKLLTLPPETTVYPGHGPTTTIGKEKASNPFLRL

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI94538322, Length=205, Percent_Identity=31.7073170731707, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI94538320, Length=200, Percent_Identity=32.5, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI21703352, Length=253, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI116642887, Length=200, Percent_Identity=30.5, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI14150041, Length=252, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI46361987, Length=198, Percent_Identity=29.7979797979798, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI41327741, Length=195, Percent_Identity=26.1538461538462, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787158, Length=209, Percent_Identity=52.1531100478469, Blast_Score=242, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI17538952, Length=197, Percent_Identity=28.4263959390863, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21356335, Length=255, Percent_Identity=27.843137254902, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24667703, Length=255, Percent_Identity=27.843137254902, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24667711, Length=255, Percent_Identity=27.843137254902, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI221330176, Length=189, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23583; Mature: 23452

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNNSMKIIVIPVTPYQQNCSLIICEETKIAAIVDPGGDPLRILNIVEKQGVKVDKIILT
CCCCCEEEEEEECCCCCCCCCEEEECCCEEEEEECCCCCCEEEEEHHHHCCCEEEEEEEE
HGHLDHVGGTQAVAGKLNVPVIGPEKEDLFWLEQLEAQSRRFGLPTTESFSPNRWLTEGE
CCCCCCCCCCCEEECCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
VLEVGKIKLKVLRIPGHTPGHIALYDKQSKQVIVGDILFNGGIGRFDFPRGNRSLLVSGI
EEEECEEEEEEEECCCCCCCEEEEEECCCCEEEEEEEEECCCCCCCCCCCCCCEEEEECH
KEKLLTLPPETTVYPGHGPTTTIGKEKASNPFLRL
HHHHEECCCCCEEECCCCCCCCCCCCCCCCCCEEC
>Mature Secondary Structure 
SNNSMKIIVIPVTPYQQNCSLIICEETKIAAIVDPGGDPLRILNIVEKQGVKVDKIILT
CCCCEEEEEEECCCCCCCCCEEEECCCEEEEEECCCCCCEEEEEHHHHCCCEEEEEEEE
HGHLDHVGGTQAVAGKLNVPVIGPEKEDLFWLEQLEAQSRRFGLPTTESFSPNRWLTEGE
CCCCCCCCCCCEEECCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
VLEVGKIKLKVLRIPGHTPGHIALYDKQSKQVIVGDILFNGGIGRFDFPRGNRSLLVSGI
EEEECEEEEEEEECCCCCCCEEEEEECCCCEEEEEEEEECCCCCCCCCCCCCCEEEEECH
KEKLLTLPPETTVYPGHGPTTTIGKEKASNPFLRL
HHHHEECCCCCEEECCCCCCCCCCCCCCCCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]