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The map label for this gene is trpS [H]

Identifier: 119943955

GI number: 119943955

Start: 218355

End: 219356

Strand: Direct

Name: trpS [H]

Synonym: Ping_0168

Alternate gene names: 119943955

Gene position: 218355-219356 (Clockwise)

Preceding gene: 119943954

Following gene: 119943959

Centisome position: 4.79

GC content: 41.72

Gene sequence:

>1002_bases
ATGACTAAACCAATAGTTTTAAGCGGTTGCCAGCCTTCGGGATCGTTAACCATAGGCAACTATATGGGCGCGTTGCGTCA
ATGGGTTGAGATGCAGAAAACCCATGACTGCCTTTTTTGTCTGGTTGATTTACATGCGATTACTGTTCGCCAGGATCCAC
AAGCACTGCGCAAAGCAATTTATGATGGTTTAGCTATGTATCAGGCTGTGGGTATTGATCCACAAAAAAGTACTATGTTT
ATTCAGTCACAAGTGACGGAACATGCAGAACTTGCATGGATATTAAACTGTTATACGCAGATGGGTGAGTTAAACCGTAT
GACCCAGTTTAAGGATAAATCACAAAAGAATATTACTAATATTAATGTGGGATTATTCAGTTACCCGGTATTGATGGCTG
CCGATATTCTTATTTATGGGCCTAAACATGTGCCTGTGGGCAGTGATCAAAAACAGCATCTTGAATTAGCACGTGATATT
GCGATCCGTTTCAATAATGCCTATGGTGATACTTTTGTGGTGCCTGAGCCTGCTATTCCTGAACATGGAGCACGTATTAT
GAGCCTGCAGGAGCCAACTAAGAAAATGTCAAAGTCCGATGATAATGTTAAAAACTTTATTGGTTTGCTGGAAGATCCAA
AAAAGATTTTGAAGAAAATTAAAAGTGCGGAGACAGACTCTGATCAGCAGGCGCGTATCTATTTTGATCCTGTTGAAAAG
CCGGGTATTTCAAATTTACTCACCTTGCTTTCCTGCTCGACGGGTAAGTCTATTGAAAGCCTGATCCCTGAATATGAAGA
TAAAATGTATGGTCATCTAAAGAGCGATACTGCAGACGCCGTAGTGAATCTCTTAGAACCAATTCAAGCCCGCTTTAAAG
AGTTGCGGAAAGATGAGACTGCATTACAAGCGATTGCGCGTGCCGGTGCACAGAAGGCGCGTGTACGTGCTGCTGATACA
TTAGCGAAGGTTTACGATAAAGTCGGTTTTTTACCAAAATAG

Upstream 100 bases:

>100_bases
GATATGTTTGTGTCTGGCTCCGCCATTTTTAATCAGCCTGATTATAAGGTTGTCATTGATAAAATGCGCGGTGAGTTAGC
TAATATTTAAGGATAGAAAA

Downstream 100 bases:

>100_bases
CCTGTTTATTGAATAAAAATAAAAAGCGCAGTGTTTGTTAATAACAACCACTGCGTTTTTTTATGCAAAGTGCTTTATGA
CCCTGCACCCAAACCCTTGC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTKPIVLSGCQPSGSLTIGNYMGALRQWVEMQKTHDCLFCLVDLHAITVRQDPQALRKAIYDGLAMYQAVGIDPQKSTMF
IQSQVTEHAELAWILNCYTQMGELNRMTQFKDKSQKNITNINVGLFSYPVLMAADILIYGPKHVPVGSDQKQHLELARDI
AIRFNNAYGDTFVVPEPAIPEHGARIMSLQEPTKKMSKSDDNVKNFIGLLEDPKKILKKIKSAETDSDQQARIYFDPVEK
PGISNLLTLLSCSTGKSIESLIPEYEDKMYGHLKSDTADAVVNLLEPIQARFKELRKDETALQAIARAGAQKARVRAADT
LAKVYDKVGFLPK

Sequences:

>Translated_333_residues
MTKPIVLSGCQPSGSLTIGNYMGALRQWVEMQKTHDCLFCLVDLHAITVRQDPQALRKAIYDGLAMYQAVGIDPQKSTMF
IQSQVTEHAELAWILNCYTQMGELNRMTQFKDKSQKNITNINVGLFSYPVLMAADILIYGPKHVPVGSDQKQHLELARDI
AIRFNNAYGDTFVVPEPAIPEHGARIMSLQEPTKKMSKSDDNVKNFIGLLEDPKKILKKIKSAETDSDQQARIYFDPVEK
PGISNLLTLLSCSTGKSIESLIPEYEDKMYGHLKSDTADAVVNLLEPIQARFKELRKDETALQAIARAGAQKARVRAADT
LAKVYDKVGFLPK
>Mature_332_residues
TKPIVLSGCQPSGSLTIGNYMGALRQWVEMQKTHDCLFCLVDLHAITVRQDPQALRKAIYDGLAMYQAVGIDPQKSTMFI
QSQVTEHAELAWILNCYTQMGELNRMTQFKDKSQKNITNINVGLFSYPVLMAADILIYGPKHVPVGSDQKQHLELARDIA
IRFNNAYGDTFVVPEPAIPEHGARIMSLQEPTKKMSKSDDNVKNFIGLLEDPKKILKKIKSAETDSDQQARIYFDPVEKP
GISNLLTLLSCSTGKSIESLIPEYEDKMYGHLKSDTADAVVNLLEPIQARFKELRKDETALQAIARAGAQKARVRAADTL
AKVYDKVGFLPK

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=331, Percent_Identity=40.4833836858006, Blast_Score=256, Evalue=2e-68,
Organism=Homo sapiens, GI41352700, Length=176, Percent_Identity=51.1363636363636, Blast_Score=189, Evalue=4e-48,
Organism=Escherichia coli, GI1789786, Length=333, Percent_Identity=63.0630630630631, Blast_Score=437, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI71982800, Length=334, Percent_Identity=33.8323353293413, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI71982793, Length=334, Percent_Identity=33.8323353293413, Blast_Score=180, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6320474, Length=345, Percent_Identity=40.8695652173913, Blast_Score=249, Evalue=4e-67,
Organism=Drosophila melanogaster, GI24666151, Length=330, Percent_Identity=43.030303030303, Blast_Score=255, Evalue=4e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37187; Mature: 37056

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPIVLSGCQPSGSLTIGNYMGALRQWVEMQKTHDCLFCLVDLHAITVRQDPQALRKAI
CCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHH
YDGLAMYQAVGIDPQKSTMFIQSQVTEHAELAWILNCYTQMGELNRMTQFKDKSQKNITN
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
INVGLFSYPVLMAADILIYGPKHVPVGSDQKQHLELARDIAIRFNNAYGDTFVVPEPAIP
EECHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCC
EHGARIMSLQEPTKKMSKSDDNVKNFIGLLEDPKKILKKIKSAETDSDQQARIYFDPVEK
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEECCCCC
PGISNLLTLLSCSTGKSIESLIPEYEDKMYGHLKSDTADAVVNLLEPIQARFKELRKDET
CCHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ALQAIARAGAQKARVRAADTLAKVYDKVGFLPK
HHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TKPIVLSGCQPSGSLTIGNYMGALRQWVEMQKTHDCLFCLVDLHAITVRQDPQALRKAI
CCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHH
YDGLAMYQAVGIDPQKSTMFIQSQVTEHAELAWILNCYTQMGELNRMTQFKDKSQKNITN
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
INVGLFSYPVLMAADILIYGPKHVPVGSDQKQHLELARDIAIRFNNAYGDTFVVPEPAIP
EECHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCC
EHGARIMSLQEPTKKMSKSDDNVKNFIGLLEDPKKILKKIKSAETDSDQQARIYFDPVEK
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEECCCCC
PGISNLLTLLSCSTGKSIESLIPEYEDKMYGHLKSDTADAVVNLLEPIQARFKELRKDET
CCHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ALQAIARAGAQKARVRAADTLAKVYDKVGFLPK
HHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]